• Title/Summary/Keyword: sequence databases

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IMPLEMENTATION OF SUBSEQUENCE MAPPING METHOD FOR SEQUENTIAL PATTERN MINING

  • Trang, Nguyen Thu;Lee, Bum-Ju;Lee, Heon-Gyu;Ryu, Keun-Ho
    • Proceedings of the KSRS Conference
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    • v.2
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    • pp.627-630
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    • 2006
  • Sequential Pattern Mining is the mining approach which addresses the problem of discovering the existent maximal frequent sequences in a given databases. In the daily and scientific life, sequential data are available and used everywhere based on their representative forms as text, weather data, satellite data streams, business transactions, telecommunications records, experimental runs, DNA sequences, histories of medical records, etc. Discovering sequential patterns can assist user or scientist on predicting coming activities, interpreting recurring phenomena or extracting similarities. For the sake of that purpose, the core of sequential pattern mining is finding the frequent sequence which is contained frequently in all data sequences. Beside the discovery of frequent itemsets, sequential pattern mining requires the arrangement of those itemsets in sequences and the discovery of which of those are frequent. So before mining sequences, the main task is checking if one sequence is a subsequence of another sequence in the database. In this paper, we implement the subsequence matching method as the preprocessing step for sequential pattern mining. Matched sequences in our implementation are the normalized sequences as the form of number chain. The result which is given by this method is the review of matching information between input mapped sequences.

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Molecular Cloning and Characterization of the Gene encoding $\beta$-N-acetylhlucosaminidases Homologue from Bombyx mandarina (멧누에(Bombyx mandarina)로부터 $\beta$-N-Acetyglunosamicidase를 코딩하는 cDNA의 분리 및 염기서열 결정)

  • 구태원;황재삼;성규병;윤은영;방혜선;권오유
    • Journal of Sericultural and Entomological Science
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    • v.41 no.3
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    • pp.147-153
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    • 1999
  • Chitinolytic enzymes such as ${\beta}$-N-acetylglucosaminidase are major hydrolases involved in insect molting. We have isolated, sequenced a CDNA encoding ${\beta}$-N-acetylglucosaminidase from the silkworm, Bombyx mandarina, and compared its sequence with genes encoding chitinolytic enyzmes from other sources. The insert DNA in the clone is 3,284 nucleotides long with an open reading frame of 1,788 nucleotides that encodes a protein of 596 amino acids with a molecular weight of 68.2 kDa. There is a 3’-untranslated region composed with 1.479 nucleotides and are several potential polyadenylation signals. The predicted amino acid sequence apparently contains a leader peptide of 23 amino acids. A search of the amino acids sequence databases for sequences similarities to other ${\beta}$-N-acetylglucosaminidases or ${\beta}$-N-acetylhexosaminidases. The highest similarity matched with the enzyme from B. mori, which has a sequence identity of 95%. On the other hand, the identity between the B. mandarina enzyme and those from M. sexta and human are 70% and 24%, respectively.

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Clustering Technique for Sequence Data Sets in Multidimensional Data Space (다차원 데이타 공간에서 시뭔스 데이타 세트를 위한 클러스터링 기법)

  • Lee, Seok-Lyong;LiIm, Tong-Hyeok;Chung, Chin-Wan
    • Journal of KIISE:Databases
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    • v.28 no.4
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    • pp.655-664
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    • 2001
  • The continuous data such as video streams and voice analog signals can be modeled as multidimensional data sequences(MDS's) in the feature space, In this paper, we investigate the clustering technique for multidimensional data sequence, Each sequence is represented by a small number by hyper rectangular clusters for subsequent storage and similarity search processing. We present a linear clustering algorithm that guarantees a predefined level of clustering quality and show its effectiveness via experiments on various video data sets.

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Implementation of Subsequence Mapping Method for Sequential Pattern Mining

  • Trang Nguyen Thu;Lee Bum-Ju;Lee Heon-Gyu;Park Jeong-Seok;Ryu Keun-Ho
    • Korean Journal of Remote Sensing
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    • v.22 no.5
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    • pp.457-462
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    • 2006
  • Sequential Pattern Mining is the mining approach which addresses the problem of discovering the existent maximal frequent sequences in a given databases. In the daily and scientific life, sequential data are available and used everywhere based on their representative forms as text, weather data, satellite data streams, business transactions, telecommunications records, experimental runs, DNA sequences, histories of medical records, etc. Discovering sequential patterns can assist user or scientist on predicting coming activities, interpreting recurring phenomena or extracting similarities. For the sake of that purpose, the core of sequential pattern mining is finding the frequent sequence which is contained frequently in all data sequences. Beside the discovery of frequent itemsets, sequential pattern mining requires the arrangement of those itemsets in sequences and the discovery of which of those are frequent. So before mining sequences, the main task is checking if one sequence is a subsequence of another sequence in the database. In this paper, we implement the subsequence matching method as the preprocessing step for sequential pattern mining. Matched sequences in our implementation are the normalized sequences as the form of number chain. The result which is given by this method is the review of matching information between input mapped sequences.

Development of Combined Architecture of Multiple Deep Convolutional Neural Networks for Improving Video Face Identification (비디오 얼굴 식별 성능개선을 위한 다중 심층합성곱신경망 결합 구조 개발)

  • Kim, Kyeong Tae;Choi, Jae Young
    • Journal of Korea Multimedia Society
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    • v.22 no.6
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    • pp.655-664
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    • 2019
  • In this paper, we propose a novel way of combining multiple deep convolutional neural network (DCNN) architectures which work well for accurate video face identification by adopting a serial combination of 3D and 2D DCNNs. The proposed method first divides an input video sequence (to be recognized) into a number of sub-video sequences. The resulting sub-video sequences are used as input to the 3D DCNN so as to obtain the class-confidence scores for a given input video sequence by considering both temporal and spatial face feature characteristics of input video sequence. The class-confidence scores obtained from corresponding sub-video sequences is combined by forming our proposed class-confidence matrix. The resulting class-confidence matrix is then used as an input for learning 2D DCNN learning which is serially linked to 3D DCNN. Finally, fine-tuned, serially combined DCNN framework is applied for recognizing the identity present in a given test video sequence. To verify the effectiveness of our proposed method, extensive and comparative experiments have been conducted to evaluate our method on COX face databases with their standard face identification protocols. Experimental results showed that our method can achieve better or comparable identification rate compared to other state-of-the-art video FR methods.

Sequence Stream Indexing Method using DFT and Bitmap in Sequence Data Warehouse (시퀀스 데이터웨어하우스에서 이산푸리에변환과 비트맵을 이용한 시퀀스 스트림 색인 기법)

  • Son, Dong-Won;Hong, Dong-Kweon
    • Journal of the Korean Institute of Intelligent Systems
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    • v.22 no.2
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    • pp.181-186
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    • 2012
  • Recently there has been many active researches on searching similar sequences from data generated with the passage of time. Those data are classified as time series data or sequence data and have different semantics from scalar data of traditional databases. In this paper similar sequence search retrieves sequences that have a similar trend of value changes. At first we have transformed the original sequences by applying DFT. The converted data are more suitable for trend analysis and they require less number of attributes for sequence comparisons. In addition we have developed a region-based query and we applied bitmap indexes which could show better performance in data warehouse. We have built bitmap indexes with varying number of attributes and we have found the least cost query plans for efficient similar sequence searches.

Global Sequence Homology Detection Using Word Conservation Probability

  • Yang, Jae-Seong;Kim, Dae-Kyum;Kim, Jin-Ho;Kim, Sang-Uk
    • Interdisciplinary Bio Central
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    • v.3 no.4
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    • pp.14.1-14.9
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    • 2011
  • Protein homology detection is an important issue in comparative genomics. Because of the exponential growth of sequence databases, fast and efficient homology detection tools are urgently needed. Currently, for homology detection, sequence comparison methods using local alignment such as BLAST are generally used as they give a reasonable measure for sequence similarity. However, these methods have drawbacks in offering overall sequence similarity, especially in dealing with eukaryotic genomes that often contain many insertions and duplications on sequences. Also these methods do not provide the explicit models for speciation, thus it is difficult to interpret their similarity measure into homology detection. Here, we present a novel method based on Word Conservation Score (WCS) to address the current limitations of homology detection. Instead of counting each amino acid, we adopted the concept of 'Word' to compare sequences. WCS measures overall sequence similarity by comparing word contents, which is much faster than BLAST comparisons. Furthermore, evolutionary distance between homologous sequences could be measured by WCS. Therefore, we expect that sequence comparison with WCS is useful for the multiple-species-comparisons of large genomes. In the performance comparisons on protein structural classifications, our method showed a considerable improvement over BLAST. Our method found bigger micro-syntenic blocks which consist of orthologs with conserved gene order. By testing on various datasets, we showed that WCS gives faster and better overall similarity measure compared to BLAST.

An Index-Based Approach for Subsequence Matching Under Time Warping in Sequence Databases (시퀀스 데이터베이스에서 타임 워핑을 지원하는 효과적인 인덱스 기반 서브시퀀스 매칭)

  • Park, Sang-Hyeon;Kim, Sang-Uk;Jo, Jun-Seo;Lee, Heon-Gil
    • The KIPS Transactions:PartD
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    • v.9D no.2
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    • pp.173-184
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    • 2002
  • This paper discuss an index-based subsequence matching that supports time warping in large sequence databases. Time warping enables finding sequences with similar patterns even when they are of different lengths. In earlier work, Kim et al. suggested an efficient method for whole matching under time warping. This method constructs a multidimensional index on a set of feature vectors, which are invariant to time warping, from data sequences. For filtering at feature space, it also applies a lower-bound function, which consistently underestimates the time warping distance as well as satisfies the triangular inequality. In this paper, we incorporate the prefix-querying approach based on sliding windows into the earlier approach. For indexing, we extract a feature vector from every subsequence inside a sliding window and construct a multidimensional index using a feature vector as indexing attributes. For query processing, we perform a series of index searches using the feature vectors of qualifying query prefixes. Our approach provides effective and scalable subsequence matching even with a large volume of a database. We also prove that our approach does not incur false dismissal. To verify the superiority of our approach, we perform extensive experiments. The results reveal that our approach achieves significant speedup with real-world S&P 500 stock data and with very large synthetic data.

An Approach for a Substitution Matrix Based on Protein Blocks and Physicochemical Properties of Amino Acids through PCA

  • You, Youngki;Jang, Inhwan;Lee, Kyungro;Kim, Heonjoo;Lee, Kwanhee
    • Interdisciplinary Bio Central
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    • v.6 no.4
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    • pp.3.1-3.10
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    • 2014
  • Amino acid substitution matrices are essential tools for protein sequence analysis, homology sequence search in protein databases and multiple sequence alignment. The PAM matrix was the first widely used amino acid substitution matrix. The BLOSUM series then succeeded the PAM matrix. Most substitution matrixes were developed by using the statistical frequency of substitution between each amino acid at blocks representing groups of protein families or related proteins. However, substitution of amino acids is based on the similarity of physiochemical properties of each amino acid. In this study, a new approach was used to obtain major physiochemical properties in multiple sequence alignment. Frequency of amino acid substitution in multiple sequence alignment database and selected attributes of amino acids in physiochemical properties database were merged. This merged data showed the major physiochemical properties through principle components analysis. Using factor analysis, these four principle components were interpreted as flexibility of electronic movement, polarity, negative charge and structural flexibility. Applying these four components, BAPS was constructed and validated for accuracy. When comparing receiver operated characteristic ($ROC_{50}$) values, BAPS scored slightly lower than BLOSUM and PAM. However, when evaluating for accuracy by comparing results from multiple sequence alignment with the structural alignment results of two test data sets with known three-dimensional structure in the homologous structure alignment database, the result of the test for BAPS was comparatively equivalent or better than results for prior matrices including PAM, Gonnet, Identity and Genetic code matrix.

Hybrid Lower-Dimensional Transformation for Similar Sequence Matching (유사 시퀀스 매칭을 위한 하이브리드 저차원 변환)

  • Moon, Yang-Sae;Kim, Jin-Ho
    • The KIPS Transactions:PartD
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    • v.15D no.1
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    • pp.31-40
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    • 2008
  • We generally use lower-dimensional transformations to convert high-dimensional sequences into low-dimensional points in similar sequence matching. These traditional transformations, however, show different characteristics in indexing performance by the type of time-series data. It means that the selection of lower-dimensional transformations makes a significant influence on the indexing performance in similar sequence matching. To solve this problem, in this paper we propose a hybrid approach that integrates multiple transformations and uses them in a single multidimensional index. We first propose a new notion of hybrid lower-dimensional transformation that exploits different lower-dimensional transformations for a sequence. We next define the hybrid distance to compute the distance between the transformed sequences. We then formally prove that the hybrid approach performs the similar sequence matching correctly. We also present the index building and the similar sequence matching algorithms that use the hybrid approach. Experimental results for various time-series data sets show that our hybrid approach outperforms the single transformation-based approach. These results indicate that the hybrid approach can be widely used for various time-series data with different characteristics.