• Title/Summary/Keyword: separated optimization

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Optimization and validation of HPLC/DAD method for the determination of adenosine and cordycepin in cordyceps products

  • Sasikarn Panpraneecharoen;Tisorn Chatrakoon;Sompong Sansenya;Saowapa Chumanee
    • Analytical Science and Technology
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    • v.36 no.4
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    • pp.152-160
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    • 2023
  • Adenosine and cordycepin are bioactive compounds with health benefits. Therefore, both substances are often used to assess the quality of Cordyceps products. Optimization and validation of the HPLC/DAD method for determining two nucleosides were studied. The samples were prepared using an ultrasound-assisted extraction (ultrasonic bath). The result was optimal conditions for aqueous extraction, an extraction time of 35 min, and an extraction temperature of 40 ℃. The Chromatographic separation was achieved using a reverse phase column (InfinityLab Poroshell 120 EC-C18, 4.6 × 250 mm, 2.7 ㎛) at 30 ℃ with a mobile phase gradient elution of water and methanol at a flow rate of 0.7 mL/min. The eluents were monitored via a diode array detector at 260 nm. Two nucleosides were separated by less than 12 min after injection. The developed method was found to be excellent linear (r2 > 0.9999), accurate (% recovery 95.34-98.51), and precise (% relative standard deviation < 2.0). The limit of detection (LOD) and quantification (LOQ) were 0.45 and 1.38 mg/mL for adenosine and 0.47 and 1.43 mg/mL for cordycepin, respectively. This method was satisfactory for simultaneously quantitating two nucleoside contents, which were used to evaluate Cordyceps products.

Modeling, Simulation and Optimization of Hydrogen Production Process from Glycerol using Steam Reforming (글리세롤로부터 수증기 개질에 의한 수소 생산공정의 모델링, 시뮬레이션 및 최적화)

  • Park, Jeongpil;Cho, Sunghyun;Lee, Seunghwan;Moon, Dong Ju;Kim, Tae-Ok;Shin, Dongil
    • Korean Chemical Engineering Research
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    • v.52 no.6
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    • pp.727-735
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    • 2014
  • For improved sustainability of the biorefinery industry, biorefinery-byproduct glycerol is being investigated as an alternate source for hydrogen production. This research designs and optimizes a hydrogen-production process for small hydrogen stations using steam reforming of purified glycerol as the main reaction, replacing existing processes relying on steam methane reforming. Modeling, simulation and optimization using a commercial process simulator are performed for the proposed hydrogen production process from glycerol. The mixture of glycerol and steam are used for making syngas in the reforming process. Then hydrogen are produced from carbon monoxide and steam through the water-gas shift reaction. Finally, hydrogen is separated from carbon dioxide using PSA. This study shows higher yield than former U.S. DOE and Linde studies. Economic evaluations are performed for optimal planning of constructing domestic hydrogen energy infrastructure based on the proposed glycerol-based hydrogen station.

A Backtracking Search Framework for Constraint Satisfaction Optimization Problems (제약만족 최적화 문제를 위한 백트래킹 탐색의 구조화)

  • Sohn, Surg-Won
    • The KIPS Transactions:PartA
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    • v.18A no.3
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    • pp.115-122
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    • 2011
  • It is very hard to obtain a general algorithm for solution of all the constraint satisfaction optimization problems. However, if the whole problem is separated into subproblems by characteristics of decision variables, we can assume that an algorithm to obtain solutions of these subproblems is easier. Under the assumption, we propose a problem classifying rule which subdivide the whole problem, and develop backtracking algorithms fit for these subproblems. One of the methods of finding a quick solution is efficiently arrange for any order of the search tree nodes. We choose the cluster head positioning problem in wireless sensor networks in which static characteristics is dominant and interference minimization problem of RFID readers that has hybrid mixture of static and dynamic characteristics. For these problems, we develop optimal variable ordering algorithms, and compare with the conventional methods. As a result of classifying the problem into subproblems, we can realize a backtracking framework for systematic search. We also have shown that developed backtracking algorithms have good performance in their quality.

A Study on Static Type Assignment for Static Single Assignment Form (정적 단일 배정 형태를 위한 정적 타입 배정에 관한 연구)

  • Kim, Ki-Tae;Yoo, Weon-Hee
    • The Journal of the Korea Contents Association
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    • v.6 no.2
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    • pp.117-126
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    • 2006
  • Although the Java bytecode has numerous advantages, there are also shortcomings such as slow execution speed and difficulty in analysis. In order to overcome such disadvantages, bytecode analysis and optimization must be performed. First control flow of the bytecode should be analyzed, after which information is required regarding where the variables are defined and used to conduct data flow analysis and optimization. There may be cases where variables with an identical name contain different values at a different location during the execution according to the value assigned to a variable in each location. Therefore, in order to statically determine the value and type, the variables must be separated according to allocation. In order to do so, the variables can be expressed using a static single assignment form. After the transformation into a static single assignment form, the type information of each node expressed by each variable and expression must be configured to perform static analysis and optimization. Based on the basic type information, this paper proposes a method for finding related equivalent nodes, setting the nodes with strongly connection components and efficiently assigning each node the type.

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Optimal deployment of bistatic sonar using particle swarm optimization algorithm (입자 군집 최적화 알고리즘을 이용한 양상태 소나 최적 배치 연구)

  • Ji Seop Kim;Dae Hyeok Lee;Wonjun Yang;Young Seung Kim;Jee Woong Choi;Hyuckjong Kwon;Jungyong Park;Su-Uk Son;Ho Seuk Bae;Joung-Soo Park
    • The Journal of the Acoustical Society of Korea
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    • v.43 no.4
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    • pp.437-444
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    • 2024
  • Bistatic sonar performance varies significantly depending on the ocean environment, the location (latitude, longitude) and water depth of the source and receiver. Therefore, research on optimal deployment of bistatic sonar considering ocean environment is necessary. In this study, we suggest an algorithm to optimize the location and water depth of source and receiver when operating monostatic and bistatic sonar on two spatially separated surface ships in the Ulleung Basin in the East Sea. A particle swarm optimization algorithm was used to search the location and water depth of the source and receiver to maximize the detectable area within the search area. As a result of performing bistatic sonar deployment using the algorithm proposed in this study, the detectable area increased as the number of model iterations increased. Additionally, it was confirmed that the source and receiver on the two surface ships converged to the optimal location and water depth.

Evaluation of Optimal Transfer Capability in Power System interconnection (연계된 계통간의 최적 송전용량 산정)

  • Son, Hyun-Il;Choi, Ah-Reum;Lee, Sung-Hoon;Kim, Jin-O;Jeon, Dong-Hoon
    • Proceedings of the KIEE Conference
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    • 2009.07a
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    • pp.195_196
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    • 2009
  • As the electrical power industry is restructured, the electrical power exchange is becoming extended. One of the key information used to determine how much power can be transferred through the network is known as available transfer capability (ATC). To calculate ATC, traditional deterministic approach is based on the severest case, but the approach has the complexity of procedure. Therefore, novel approach for ATC calculation is proposed using cost-optimization method in this paper, and is compared with well-being method and risk-benefit method. This paper proposes the optimal transfer capability of HVDC system between mainland and a separated island in Korea through these three methods. These methods will consider production cost, wheeling charge through HVDC system and outage cost with one depth (N-1 contingency).

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A Method for Optimal Location of Feeder Tie Switches for Improving Equal Load of Electric Power Equipment in Distribution Automation System (배전자동화 시스템에서 전력설비 부하균등화를 고려한 피더간 연계점 최적위치선정)

  • Lim, Il-Hyung;Lim, Seong-Il;Choi, Myeon-Song;Lee, Seung-Jae;Shin, Chang-Hoon;Ha, Bok-Nam
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.5
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    • pp.821-828
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    • 2007
  • This paper proposes a new algorithm to find optimal location of open switches connecting feeders in distribuion system. In order to enhance power system reliability by minimizing outage area in case of fault, the load balance among the facilities such as transformers and feeders is considered to optimize. The combination of optimal position of normal open switches can be found by moving tie along the direct path connecting two feeders related to the open switch while the whole optimization problem is separated into many small problems. The proposed algorithm is shown by case study results that, it is simple and takes short calculation time to apply to the DAS (Distribution Automation System) in KEPCO (Korea Electric Power Cooperation).

Characteristics of Spatial Coded Binary Phase Only Filter Applied by Simulated Annealing Algorithm (Simulated Annealing 알고리즘을 적용한 이진공간부호필터 특성)

  • 박성균;정창규;전석희;박한규
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.31A no.9
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    • pp.64-71
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    • 1994
  • In this study, optimizing BPOFs are encoded by Simulated Annealing algorithm that is widely used among the optimization algorithms. Two BPOFs are trained by digit patterns, 0~9, and the digits each having 4 intraclass patterns are multiplexed. When each digit is encoded by four bit binary code, from the results of computer simulation, the correlation pezk is shown at binary value 1 position among the spatially separated four positions at the correlation plane And then, the designed BPOFs are implemented by CGH technique. Through the optical correlation experiment, satisactory results are achieved, inspite of some experimental errors and information loss owing to the amplitude type CGH filter.

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Co-Production of Dextran and Mannitol by Leuconostoc mesenteroides

  • YOO, SUN KYUN;DOMAN KIM;DONAL F. DAY
    • Journal of Microbiology and Biotechnology
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    • v.11 no.5
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    • pp.880-883
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    • 2001
  • To optimize co-production of dextran and mannitol from sucrose by Leuconostoc mesenterides ATCC 13146, a batch culture fermentation was conducted by using various concentrations of sucrose and initial culture pHs. The production of dextran and mannitol showed a growth-associated pattern. The highest yields of both dextran and mannitol were obtained at pH 6.0 and $10\%$ (w/v) sucrose. They could be easily separated by using alcohol fractionation. Maximum yields of dexran and mannitol were 0.45 and 0.35 of the consumed sucrose, respectively. Overall productivities of dextran and mannitol were 1.47 and 0.37 g/l/h, respectively.

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Particle Imaging Velocimetry using Genetic Algorithm (유전적 알고리듬에 의한 PIV계측법)

  • Doh, Deog-Hee;Cho, Yong-Beom;Hong, Seong-Dae
    • Proceedings of the KSME Conference
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    • 2000.04b
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    • pp.650-654
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    • 2000
  • Particle Imaging Velocimetry (PIV) is becoming one of essential methods to measure velocity fields of fluid flows. In this paper, a genetic algorithm capable of tracking same particle pairs on two separated images is introduced. The fundamental of the developed technique is based on that on-to-one correspondence is found between two tracer particles selected in two image planes by taking advantage of combinatorial optimization of the genetic algorithm. The fitness function controlling reproductive success in the genetic algorithm is expressed by physical distances between the selected tracer particles. The capability of the developed genetic algorithm is verified by a computer simulation on a farced vortex flow.

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