• Journal of the Korean Mathematical Society
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• v.59 no.6
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• pp.1153-1170
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• 2022

In this paper, we investigate the portfolio optimization problem under the SVCEV model, which is a hybrid model of constant elasticity of variance (CEV) and stochastic volatility, by taking into account of minimum-entropy robustness. The Hamilton-Jacobi-Bellman (HJB) equation is derived and the first two orders of optimal strategies are obtained by utilizing an asymptotic approximation approach. We also derive the first two orders of practical optimal strategies by knowing that the underlying Ornstein-Uhlenbeck process is not observable. Finally, we conduct numerical experiments and sensitivity analysis on the leading optimal strategy and the first correction term with respect to various values of the model parameters.

• Journal of Ginseng Research
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• v.48 no.3
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• pp.276-285
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• 2024

Diabetes mellitus (DM) is a systemic disorder of energy metabolism characterized by a sustained elevation of blood glucose in conjunction with impaired insulin action in multiple peripheral tissues (i.e., insulin resistance). Although extensive research has been conducted to identify therapeutic targets for the treatment of DM, its global prevalence and associated mortailty rates are still increasing, possibly because of challenges related to long-term adherence, limited efficacy, and undesirable side effects of currently available medications, implying an urgent need to develop effective and safe pharmacotherapies for DM. Phytochemicals have recently drawn attention as novel pharmacotherapies for DM based on their clinical relevance, therapeutic efficacy, and safety. Ginsenosides, pharmacologically active ingredients primarily found in ginseng, have long been used as adjuvants to traditional medications in Asian countries and have been reported to exert promising therapeutic efficacy in various metabolic diseases, including hyperglycemia and diabetes. This review summarizes the current pharmacological effects of ginsenosides and their mechanistic insights for the treatment of insulin resistance and DM, providing comprehensive perspectives for the development of novel strategies to treat DM and related metabolic complications.

• Journal of Environmental Health Sciences
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• v.46 no.5
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• pp.576-587
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• 2020

Objectives: This study calculated local residents exposures to VOCs (Volatile Organic Compounds) released into the atmosphere using the CalTOX model and carried out uncertainty analysis and sensitivity analysis. The model validity was analyzed by comparing the predicted and the actual atmospheric concentrations. Methods: Uncertainty was parsed by conducting a Monte Carlo simulation. Sensitivity was dissected with the regression (coefficients) method. The model validity was analyzed by applying r² (coefficient of determination), RMSE (root mean square error), and the Nash-Sutcliffe EI (efficiency index) formula. Results: Among the concentrations in the atmosphere in this study, benzene was the highest and the lifetime average daily dose of benzene and the average daily dose of xylene were high. In terms of the sensitivity analysis outcome, the source term to air, exposure time, indoors resting (ETri), exposure time, outdoors at home (ETao), yearly average wind speed (v_w), contaminated area in ㎡ (Area), active breathing rate (BRa), resting breathing rate (BRr), exposure time, and active indoors (ETai) were elicited as input variables having great influence upon this model. In consequence of inspecting the validity of the model, r² appeared to be a value close to 1 and RMSE appeared to be a value close to 0, but EI indicated unacceptable model efficiency. To supplement this value, the regression formula was derived for benzene with y=0.002+15.48x, ethylbenzene with y ≡ 0.001+57.240x, styrene with y=0.000+42.249x, toluene with y=0.004+91.588x, and xylene with y=0.000+0.007x. Conclusions: In consequence of inspecting the validity of the model, r² appeared to be a value close to 1 and RMSE appeared to be a value close to 0, but EI indicated unacceptable model efficiency. This will be able to be used as base data for securing the accuracy and reliability of the model.

• The Korean Journal of Nuclear Medicine Technology
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• v.14 no.2
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• pp.181-185
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• 2010

Purpose: Several studies report that detection of thyroglobulin (Tg) in fine-needle aspiration (FNA) biopsy washout fluid from lymph nodes identifies recurrences or metastases of differentiated papillary thyroid cancer (DPTC) in the neck with higher sensitivity and specificity than fine-needle aspiration cytology (FNAC). We evaluate the diagnostic efficacy and usefulness of Tg measurement in FNA washout fluid (FNA-Tg) and compare with FNAC. Materials and Methods: Forty-eight FNA samples of 37 patients who undergone ultrasonography to detect cervical lymph node metastasis of DPTC, were included for this study. Lymph node metastasis was confirmed by histopathologic examination or long-term imaging follow-up. Sensitivity, specificity and accuracy of FNA-Tg and FNAC were calculated. In 34 patients, we evaluated diagnostic accuracy of FNA-Tg according to the presence or absence of Tg antibody. Results: Sensitivity, specificity and accuracy of FNAC were 75.0%, 97.2% and 91.7%, respectively, and those of FNA-Tg were 100%, 88.9% and 91.7%, respectively. The presence of Tg antibody was not relevant to the diagnostic accuracy of FNA-Tg. Conclusion: FNA-Tg is a as accurate as FNAC with higher sensitivity. FNA-Tg and FNAC are complement techniques for diagnosing lymph node metastasis of DTPC.

• The Korean Journal of Pesticide Science
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• v.4 no.2
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• pp.1-10
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• 2000

Fungicide resistance study in Korea is still in its infancy, and most of those resistance studies are largely limited to newness of the detected resistant strains. In future, detection of fungicide-resistant strains has to be based on sensitivity distribution of pathogen populations to certain fungicides, and standard levels of certain fungicides for resistance should be determined under the basis of this data. Most of the early research on fungicide resistance in Korea has overlooked this point, and resulted in inconsistency and confusion for monitoring sensitivity shift of pathogen population among individual researchers. Fungicide resistance detected in vitro tests has to be documented in field trials by examining control efficacy against resistant and wild-type pathogen populations. Resistance detection in wife has to be correlated with lower activity in practice. Using this process, fungicide resistance will have a practical meaning. Fitness evaluation of resistant strains for survival is, in particular, of importance to determine the future stability of the resistance in the pathogen population. In fields, sensitivity change of pathogen populations should be carefully monitored with and without fungicide selection pressures to establish long-term management strategies against fungicide resistance. It is becoming an urgent task to provide information through research for designing and implementing successful counter-measures against fungicide resistance problems in Korea.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.11 no.6
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• pp.11-26
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• 2016

Businesses have to survive and thrive in both domestic and international environments. In order to resolve these problems, new alternatives have been presented. These include the importance of women's resources and entrepreneurship of female CEOs. The sensibility, delicacy, creativity as well as the intuitive power of female CEOs, actively enables them to cope with the ever-changing environment. Because of the rapidly changing circumstances, the above mentions women's attributes are highlighted thus, causing women's roles in society to shift from their traditional tendencies to finding careers and their own identities. Due to this change in social roles, social interest and the values of female CEOs are being reevaluated. Accordingly, the conceptual consideration of female entrepreneurship (innovation, enterprise, risk sensitivity) as well as the factors to be considered for the entrepreneurship of female CEOs in order to promote knowledge management performance was derived in this research. The deducted implication of this research is that generally, the enterprise and risk sensitivity of entrepreneurship affect the knowledge management performance of female CEOs. It is therefore proved that in the case of female CEOs, entrepreneurship and self-efficacy are linked, allowing them to achieve the desired outcome for a specific task performance. Female CEOs are capable of company management through the mediating process of their enterprise, risk sensitivity, and self-efficacy and with faith in their knowledge management, will be able to achieve high performance. Therefore, using strengths and nature peculiar to women, women's economic activities derived from knowledge management based on entrepreneurship will not only help overcome the long-term economy crisis but also lead to high economic growth and development. This will be a dynamic force for the nation's new growth with financial means. The comparative study of existing results will also contribute in suggesting the direction of policies that will enable the success of female CEOs in entrepreneurship.

• Korean Journal of Environment and Ecology
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• v.38 no.1
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• pp.67-78
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• 2024

The term ecosystem services refers to natural ecosystems' benefits to humans. Various models have been developed and applied to quantify ecosystem services. Habitat quality assessment is a widely used leading InVEST ecosystem service model. In Korea, habitat quality assessment is conducted for national parks. For habitat quality assessment, the initial value of habitat quality must be used to assess the sensitivity to threats, which varies depending on the country and application field. Therefore, an expert survey (AHP) was conducted based on previous habitat quality assessments in national parks to adjust the sensitivity, the initial value for the habit quality assessment. As a result of the AHP, 18 items were adjusted, including 10 items, such as natural grassland and unarranged fields, upward and 8 items, such as rivers and ponds, downward. Based on the adjusted sensitivity results, the habitat quality of Bukhansan National Park and Gyeryongsan National Park (urban type), Gyeongju National Park (historic type), Hallyeohaesang National Park (ocean type), and Jirisan National Park and Seoraksan National Park (mountain type) were adjusted. The results of the analysis showed that the habitat quality of urban dry areas and water bodies distributed in the national parks was reflected in the habitat quality assessment. In the future, it will be possible to evaluate the habitat quality of natural parks using this standard.

• Journal of the Korea Concrete Institute
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• v.21 no.5
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• pp.629-638
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• 2009

In this paper, the existing formulas of the step-by-step method were generalized for effective estimation of responses of complicated composite sections due to long-term deformation of concrete. The initial transformed section properties of the composite section were derived from material and section properties of concrete section and sections which confine the longterm deformation of concrete. The transformed section properties at each step were derived from the effective modulus of elasticity considered the creep coefficient variation. Improved formulas of the step-by-step method for generalized responses were derived by introducing 5 generalized parameters. The formulas can be more simplified by applying constant increment of creep coefficient at each step. The constant increment of creep coefficient at each step can also reduce computing time and make equal computing error of each step. The generalized responses for axial elastic strain of concrete section were most sensitive to the area rate of concrete section, and the ratio of the second moment of the confining section area was more sensitive than that of the concrete section. Those for elastic curvature of concrete section were most sensitive to the ratio of the second moment of concrete section area.

• Transactions of the KSME C: Technology and Education
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• v.2 no.2
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• pp.89-97
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• 2014

The diesel driven power generation facility provides most of electricity of island region where is isolated from the main land power supply system. It is possible to extend the life of diesel driven power generation facility by periodic maintenance. However, the long-term use of diesel driven power generation facility increases the operating cost due to aging hardware and reduced plant efficiency. In other words, on-time replacement of aging diesel driven power generation facility reduces plant operation cost. The purpose of this study presents major indicators to represent the characteristics of the diesel generator and conducts sensitivity analysis using Monte Carlo analysis. In addition, status core which indicates quantitatively the state of the diesel driven power generation facility is defined and prepare the replacement criteria based on the state score.

• Journal of Korea Water Resources Association
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• v.30 no.6
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• pp.597-610
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• 1997

One-dimensional numerical models using finite difference methods for unsteady sediment transport on alluvial river channel are developed. The Preissmann implicit scheme and the Lax-Wendroff two-step explicit scheme with the Method of Characteristics for water motion and a forward time centered space explicit scheme for sediment motion are developed to simulate the sediment transport rate and the variation of channel bed level. The program correctness of each model is successfully verified using volume conservation tests. The sensitivity studies show that higher peak stage level, steeper channel slope and longer flooding duration produce more channel bed erosion. and median grain size, $D_{50}=0.4mm$ give maximum volume loss in this study. Finally, the numerical models are found to produce reasonable results from the various sensitivity tests which reveal that the numerical models have properly responded to the changes of each model parameter.