• Title/Summary/Keyword: sensitivity term

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Elevation of heart-femoral pulse wave velocity by short-term low sodium diet followed by high sodium diet in hypertensive patients with sodium sensitivity

  • Rhee, Moo-Yong;Kim, Ji-Hyun;Na, Sang-Hoon;Chung, Jin-Wook;Bae, Jun-Ho;Nah, Deuk-Young;Gu, Namyi;Kim, Hae-Young
    • Nutrition Research and Practice
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    • v.10 no.3
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    • pp.288-293
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    • 2016
  • BACKGROUND/OBJECTIVES: We compared changes in heart-femoral pulse wave velocity (hfPWV) in response to low sodium and high sodium diet between individuals with sodium sensitivity (SS) and resistance (SR) to evaluate the influence of sodium intake on arterial stiffness. SUBJECTS/METHODS: Thirty-one hypertensive and 70 normotensive individuals were given 7 days of low sodium dietary approach to stop hypertension (DASH) diet (LSD, 100 mmol NaCl/day) followed by 7 days of high sodium DASH diet (HSD, 300 mmol NaCl/day) during 2 weeks of hospitalization. The hfPWV was measured and compared after the LSD and HSD. RESULTS: The hfPWV was significantly elevated from LSD to HSD in individuals with SS (P = 0.001) independently of changes in mean arterial pressure (P = 0.037). Conversely, there was no significant elevation of hfPWV from LSD to HSD in individuals with SR. The percent change in hfPWV from the LSD to the HSD in individuals with SS was higher than that in individuals with SR. Subgroup analysis revealed that individuals with both SS and hypertension showed significant elevation of hfPWV from LSD to HSD upon adjusted analysis using changes of the means arterial pressure (P = 0.040). However, there was no significant elevation of hfPWV in individuals with SS and normotension. CONCLUSION: High sodium intake elevated hfPWV in hypertensive individuals with SS, suggesting that high sodium intake increases aortic stiffness, and may contribute to enhanced cardiovascular risk in hypertensive individuals with SS.

Corporate Social Responsibility and Executive Performance -Impact on Compensation Sensitivity (기업의 사회적 책임이 경영자 성과-보상민감도에 미치는 영향)

  • Hwang, Seong-Jun;Kim, Dong-Il
    • Journal of the Korea Convergence Society
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    • v.10 no.9
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    • pp.221-228
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    • 2019
  • Companies are making great efforts to integrate CSR into various aspects of their management strategies. A lot of research has been conducted on what management intends to do indirectly and indirectly. Was performed. In this study, we conducted additional research considering executive compensation as an indicator of the motivation for management to participate in CSR. The main purpose of this study was to analyze whether accounting performance measures or market performance measures are given more weight when providing rewards for performance to corporate managers conducting CSR activities. The analysis of the relationship between CSR and executive performance-reward sensitivity showed that corporate executives who actively implement CSR pay more weight to market performance measures rather than accounting performance measures. Considering the long-term performance of CSR when paying executives' compensation, the company pays more for market performance than accounting performance. This study is expected to be useful for executives to design compensation contracts to actively induce CSR implementation.

Fabrication of Pt/Carbon Nanotube Composite Based Electrochemical Hydrogen Sulfide Gas Sensor using 3D Printing (3D 프린팅을 이용한 Pt/Carbon Nanotube composite 기반 전기화학식 황화수소 가스 센서 제작)

  • Yuntae Ha;JinBeom Kwon;Suji Choi;Daewoong Jung
    • Journal of Sensor Science and Technology
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    • v.32 no.5
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    • pp.290-294
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    • 2023
  • Among various types of harmful gases, hydrogen sulfide is a strong toxic gas that is mainly generated during spillage and wastewater treatment at industrial sites. Hydrogen sulfide can irritate the conjunctiva even at low concentrations of less than 10 ppm, cause coughing, paralysis of smell and respiratory failure at a concentration of 100 ppm, and coma and permanent brain loss at concentrations above 1000 ppm. Therefore, rapid detection of hydrogen sulfide among harmful gases is extremely important for our safety, health, and comfortable living environment. Most hydrogen sulfide gas sensors that have been reported are electrical resistive metal oxide-based semiconductor gas sensors that are easy to manufacture and mass-produce and have the advantage of high sensitivity; however, they have low gas selectivity. In contrast, the electrochemical sensor measures the concentration of hydrogen sulfide using an electrochemical reaction between hydrogen sulfide, an electrode, and an electrolyte. Electrochemical sensors have various advantages, including sensitivity, selectivity, fast response time, and the ability to measure room temperature. However, most electrochemical hydrogen sulfide gas sensors depend on imports. Although domestic technologies and products exist, more research is required on their long-term stability and reliability. Therefore, this study includes the processes from electrode material synthesis to sensor fabrication and characteristic evaluation, and introduces the sensor structure design and material selection to improve the sensitivity and selectivity of the sensor. A sensor case was fabricated using a 3D printer, and an Ag reference electrode, and a Pt counter electrode were deposited and applied to a Polytetrafluoroethylene (PTFE) filter using PVD. The working electrode was also deposited on a PTFE filter using vacuum filtration, and an electrochemical hydrogen sulfide gas sensor capable of measuring concentrations as low as 0.6 ppm was developed.

Metal Oxide Thin Film Transistor with Porous Silver Nanowire Top Gate Electrode for Label-Free Bio-Relevant Molecules Detection

  • Yu, Tae-Hui;Kim, Jeong-Hyeok;Sang, Byeong-In;Choe, Won-Guk;Hwang, Do-Gyeong
    • Proceedings of the Korean Vacuum Society Conference
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    • 2016.02a
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    • pp.268-268
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    • 2016
  • Chemical sensors have attracted much attention due to their various applications such as agriculture product, cosmetic and pharmaceutical components and clinical control. A conventional chemical and biological sensor is consists of fluorescent dye, optical light sources, and photodetector to quantify the extent of concentration. Such complicated system leads to rising cost and slow response time. Until now, the most contemporary thin film transistors (TFTs) are used in the field of flat panel display technology for switching device. Some papers have reported that an interesting alternative to flat panel display technology is chemical sensor technology. Recent advances in chemical detection study for using TFTs, benefits from overwhelming progress made in organic thin film transistors (OTFTs) electronic, have been studied alternative to current optical detection system. However numerous problems still remain especially the long-term stability and lack of reliability. On the other hand, the utilization of metal oxide transistor technology in chemical sensors is substantially promising owing to many advantages such as outstanding electrical performance, flexible device, and transparency. The top-gate structure transistor indicated long-term atmosphere stability and reliability because insulator layer is deposited on the top of semiconductor layer, as an effective mechanical and chemical protection. We report on the fabrication of InGaZnO TFTs with silver nanowire as the top gate electrode for the aim of chemical materials detection by monitoring change of electrical properties. We demonstrated that the improved sensitivity characteristics are related to the employment of a unique combination of nano materials. The silver nanowire top-gate InGaZnO TFTs used in this study features the following advantages: i) high sensitivity, ii) long-term stability in atmosphere and buffer solution iii) no necessary additional electrode and iv) simple fabrication process by spray.

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Factors Affecting the Compliance of Standard Precautions in Long Term care Hospital nurses (요양병원 간호사의 표준주의지침 수행도에 미치는 영향요인)

  • Jang, Mi Ok;Lee, Jin Hee
    • Journal of the Korean Applied Science and Technology
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    • v.38 no.3
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    • pp.813-823
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    • 2021
  • This study was conducted to identify the factors affecting the compliance of standard precautions for nurses working in long term care hospitals. As a result of the analysis, 8.50 points in perception of the standard precautions, 3.76 points in health beliefs(subcategories- 4.03 points in perceived sensitivity, 4.04 points in perceived seriousness, 3.91 points in perceived benefits, 3.54 points in perceived barrier, 2.92 points in cues to action), 37.90 points in compliance status of the standard precautions. The performance of the standard precautions was positively correlated with perception of the standard precautions(r=0.419, p=.001) and health beliefs (r=0.443, p<.001), perceived sensitivity (r=0.169, p=.044), perceived barrier(r=0.486, p<.001), perceived benefits (r=0.207, p=.013), cues to action (r=0.204, p=.014). The compliance status of the standard precautions was influenced by the perceived barrier(β=0.373, p<.001), cues to action (β=0.271, p<.001), perception of the standard precautions(β=0.245, p=.004)explanatory power was 32.5%.

Factors to Predict a Remission after Short-Term Pharmacotherapy in Korean Panic Disorder Patients (한국인 공황장애 환자에서 단기간 약물치료 후 관해 예측인자 연구)

  • Sim, Hyun-Bo;Kang, Eun-Ho;Yu, Bum-Hee
    • Anxiety and mood
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    • v.3 no.2
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    • pp.110-115
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    • 2007
  • Objective : The authors examined the treatment response and remission rates in patients with panic disorder after short-term pharmacotherapy in an effort to determine the factors that can be used to predict remission in Korean patients with panic disorder. Methods : Sixty-one patients with panic disorder were recruited for participation in this study. The psychological symptoms of the patients were measured using the HAMA, HAMD, STAIS, STAIT, ASI and API at baseline and after 3 months of pharmacotherapy. Results : Patients with panic disorder showed significantly lower scores on all psychological measures after 3 months of pharmacotherapy with paroxetine. The remission rate was 44.3%, and the response rate was 54.1%. The remitters showed significantly lower HAMD, HAMA, STAIS, STAIT, and ASI scores than the non-remitters. Linear regression analysis revealed that the baseline HAMA, HAMD, and ASI scores could be used to predict the remission rate after controlling for age, sex and agoraphobia. Conclusion : Compared with previous reports, our study showed a similar remission rate in Korean patients with panic disorder. Lower baseline levels of anxiety, depression, and anxiety sensitivity were found to be predictors of treatment remission in panic disorder.

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AUTONOMIC MECHANISMS OF AN ACUTE STRESS RESPONSE DURING WORD RECOGNITION TASK PERFORMANCE WITH INTENSE NOISE BACKGROUND (백색소음하의 단어재인검사 수행에 따른 자율신경계 스트레스 반응)

  • ;;;Estate Sokhadze
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • 1999.03a
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    • pp.127-132
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    • 1999
  • Cardiovascular, respiratory and electrodermal responses to acute stress episodes modeled by combined presentation of intense white noise and performance of word recognition task with noise background were studied in 15 college students. Experimental procedure consisted in sessions with white noise, word recognition task presentation with noise background and test with noise background. Recorded physiological variables were analyzed in terms of their sensitivity to detect activation of sympathetic and parasympathetic branches of autonomic nervous system and thus reflect autonomic arousal level during shout-term stress-inducing experimental manipulations. It was shown that performance of effortful mental task with noise background elicited significant physiological responses typical for active coping behavior, namely electrodermal arousal and increased cardiovascular activity. this response profile was more profound as compared to white noise only or attending task in noise background. However, all physiological responses were mostly phasic, without long-term tonic changes, since almost all variables recovered to their initial baseline levels, suggesting that dominant autonomic mechanisms in transient acute stress episodes were of parasympathetic nature (withdrawal in stress with subsequent activation in restoration period), while sympathetic contribution was not long-lasting. Nevertheless, increased number of stressors and their longer exposure may result in higher profile of tonic sympathetic arousal and reduced functional role of vagal mechanisms in autonomic balance regulation.

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Rapid prediction of long-term deflections in composite frames

  • Pendharkar, Umesh;Patel, K.A.;Chaudhary, Sandeep;Nagpal, A.K.
    • Steel and Composite Structures
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    • v.18 no.3
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    • pp.547-563
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    • 2015
  • Deflection in a beam of a composite frame is a serviceability design criterion. This paper presents a methodology for rapid prediction of long-term mid-span deflections of beams in composite frames subjected to service load. Neural networks have been developed to predict the inelastic mid-span deflections in beams of frames (typically for 20 years, considering cracking, and time effects, i.e., creep and shrinkage in concrete) from the elastic moments and elastic mid-span deflections (neglecting cracking, and time effects). These models can be used for frames with any number of bays and stories. The training, validating, and testing data sets for the neural networks are generated using a hybrid analytical-numerical procedure of analysis. Multilayered feed-forward networks have been developed using sigmoid function as an activation function and the back propagation-learning algorithm for training. The proposed neural networks are validated for an example frame of different number of spans and stories and the errors are shown to be small. Sensitivity studies are carried out using the developed neural networks. These studies show the influence of variations of input parameters on the output parameter. The neural networks can be used in every day design as they enable rapid prediction of inelastic mid-span deflections with reasonable accuracy for practical purposes and require computational effort which is a fraction of that required for the available methods.

A Conservative Safety Study on Low-Level Radioactive Waste Repository Using Radionuclide Release Source Term Model (선원항 모델을 사용한 저준위 방사성폐기물 처분장의 보수적인 안전성고찰)

  • Kim, Chang-Lak;Lee, Myung-Chan;Cho, Chan-Hee
    • Nuclear Engineering and Technology
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    • v.25 no.1
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    • pp.63-70
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    • 1993
  • A simplified safety assessment is carried out on rock-cavern type disposal of LLW using the analytical repository source term (REPS) model. For reliable prediction of the leach rates for various radionuclides, degradation of concrete structures, corrosion rate of waste container, degree of corrosion on the container surface, and the characteristics of radionuclides are considered in the REPS model. The results of preliminary assessment show that Cs-137, Ni-63, and Sr-90 are dominant. For the parametric uncertainty and sensitivity analysis, Latin hypercube sampling technique and rank correlation technique are applied. The results of the potential public health impacts show that radiological dose to intruder in the worst case scenario will be negligible and that more attention should be given to near-field performance.

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Prediction of Significant Wave Height in Korea Strait Using Machine Learning

  • Park, Sung Boo;Shin, Seong Yun;Jung, Kwang Hyo;Lee, Byung Gook
    • Journal of Ocean Engineering and Technology
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    • v.35 no.5
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    • pp.336-346
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    • 2021
  • The prediction of wave conditions is crucial in the field of marine and ocean engineering. Hence, this study aims to predict the significant wave height through machine learning (ML), a soft computing method. The adopted metocean data, collected from 2012 to 2020, were obtained from the Korea Institute of Ocean Science and Technology. We adopted the feedforward neural network (FNN) and long-short term memory (LSTM) models to predict significant wave height. Input parameters for the input layer were selected by Pearson correlation coefficients. To obtain the optimized hyperparameter, we conducted a sensitivity study on the window size, node, layer, and activation function. Finally, the significant wave height was predicted using the FNN and LSTM models, by varying the three input parameters and three window sizes. Accordingly, FNN (W48) (i.e., FNN with window size 48) and LSTM (W48) (i.e., LSTM with window size 48) were superior outcomes. The most suitable model for predicting the significant wave height was FNN(W48) owing to its accuracy and calculation time. If the metocean data were further accumulated, the accuracy of the ML model would have improved, and it will be beneficial to predict added resistance by waves when conducting a sea trial test.