• Journal of Adhesion and Interface
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• v.4 no.1
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• pp.43-50
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• 2003

점착제는 경피흡수제제(transdermal drug delivery system, TDDS)의 중요한 구성요소 중의 하나이다. TDDS용 점착제는 일반적인 점착제의 역할 외에도 부착되는 피부에 적합해야 하고, 이것에 포함되는 약물 및 첨가제들과 양립하면서 약물의 전달을 효과적으로 지속해야한다. 본 총설에서는 흔히 사용되는 TDDS용 점착제인 polyisobutylenes, polyacrylates, silicones와 최근에 개발된 제품들을 소개한다.

• Korean Journal of Agricultural and Forest Meteorology
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• v.7 no.3
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• pp.220-226
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• 2005

We investigated the effect of $O_3$ on the photosynthetic characteristics of oriental plane (Platanus orientalis L.) that is used as a side tree or ornamental tree in Korea. Two-year-old oriental plane seedlings were transplanted to pots and transferred into a closed $O_3$ chamber, Photosynthetic pigment content and photosynthetic characteristics of leaves were measured every three weeks during 100 ppb $O_3$ fumigation. There was no visible foliar injury by $O_3$ exposure and the content of photosynthetic pigments did not show significant differences between control and $O_3$-treated seedlings. But photosynthetic rate, stomatal conductance, and water use efficiency in leaves of $O_3$-treated seedlings were reduced after six weeks of ozone fumigation. In addition, reduction of carboxylation efficiency and photochemical efficiency was observed in leaves of $O_3$-treated seedlings after three weeks and six weeks. In accordance with our results, carboxylation efficiency, the most sensitive parameter to $O_3$ stress, was considered to be a suitable indicator of $O_3$ sensitivity.

• Proceedings of the Korea Water Resources Association Conference
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• 2019.05a
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• pp.153-153
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• 2019

Evapotranspiration (ET) is an important component of hydrological processes. Accurate estimates of ET variation are of vital importance for natural hazard adaptation and water resource management. This study first developed a soil water index (SWI)-based Priestley-Taylor algorithm (SWI-PT) based on the enhanced vegetation index (EVI), SWI, net radiation, and temperature. The algorithm was then compared with a modified satellite-based Priestley-Taylor ET model (MS-PT). After examining the performance of the two models at 10 flux tower sites in different land cover types over East Asia and Australia, the daily estimates from the SWI-PT model were closer to observations than those of the MS-PT model in each land cover type. The average correlation coefficient of the SWI-PT model was 0.81, compared with 0.66 in the original MS-PT model. The average value of the root mean square error decreased from $36.46W/m^2$ to $23.37W/m^2$ in the SWI-PT model, which used different variables of soil moisture and vegetation indices to capture soil evaporation and vegetative transpiration, respectively. By using the EVI and SWI, uncertainties involved in optimizing vegetation and water constraints were reduced. The estimated ET from the MS-PT model was most sensitive (to the normalized difference vegetation index (NDVI) in forests) to net radiation ($R_n$) in grassland and cropland. The estimated ET from the SWI-PT model was most sensitive to $R_n$, followed by SWI, air temperature ($T_a$), and the EVI in each land cover type. Overall, the results showed that the MS-PT model estimates of ET in forest and cropland were weak. By replacing the fraction of soil moisture ($f_{sm}$) with the SWI and the NDVI with the EVI, the newly developed SWI-PT model captured soil evaporation and vegetation transpiration more accurately than the MS-PT model.

• Proceedings of the Korea Water Resources Association Conference
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• 2005.05b
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• pp.578-582
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• 2005

In this study, the conceptual foundation and development process of the Antecedent soil Moisture Condition(AMC) in SCS runoff curve number method are reviewed. Although the runoff volume is very sensitive with AMC condition, the AMC class limits developed in SCS(1972) are used in rainfall-runoff analysis without careful consideration. Tn this study, following the SCS curve number development process, rainfall-runoff characteristics of the Jang-Pyung subbasin subject to the Pyung-Chang River basin are analyzed to evaluate the reasonability of the AMC class limits at present. The New AMC class limits are proposed by the sensitive analysis of the antecedent rainfall - curve number value. As a result, the classification value of AMC-I with II is 22mm of antecedent 5-day rainfall amount, and the classification of AMC-II with III is 117mm in growing season. When the New AMC class limits are applied to Jang-Pyung subbasin, AMC probability distribution shows that the AMC-II has increased remarkably even though the AMC-I has a little higher value. But the AMC-III has the smallest one. According to the conceptual basis of the curve number method, the AMC probability distribution, the New AMC class limits adopted, gives reasonable results.

• Food Science of Animal Resources
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• v.30 no.5
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• pp.795-803
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• 2010

A DF01 strain that inhibits tyramine-producing Lactobacillus curvatus KFRI 166 was isolated from Dongchimi, a traditional Korean fermented vegetable, and identified as Lactobacillus brevis by biochemical analysis and reverse transcriptase sequencing of 16S rRNA. The antimicrobial compound produced by L. brevis DF01 was secreted at a maximum level of 640 AU/mL in late exponential phase in MRS broth, and its activity remained constant during stationary phase. The activity of bacteriocin DF01 was totally inactivated by $\alpha$-chymotrypsin, pronase E, proteinase K, trypsin, and $\alpha$-amylase, but not by catalase, which indicates the compound was glycoprotein in nature. The activity was not affected by pH changes ranging from 2 to 12 or heat treatment (60, 80, and $100^{\circ}C$ for 30 min), but was reduced after autoclaving. Bacteriocin DF01 had bacteriolytic activity and a molecular weight of approximately 8.2 kDa, as shown by tricine-SDS-PAGE analysis. Therefore, bacteriocin DF01 can be used in the manufacture of fermented meat products due to its inhibition of tyramine-producing L. curvatus and non-inhibition of L. sake, which is used as a starter culture for meat fermentation.

• Journal of Korea Water Resources Association
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• v.37 no.8
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• pp.687-693
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• 2004

The MODFLOW simulated results with varying input parameter values were compared and analyzed. To understand the relative importance of the input parameters, sensitivity analysis was carried out. The amount of sustainable yield was analyzed with respect to the hydraulic conductivity, specific yield, specific storage, aquifer thickness and the distance of the wells from the river. The results of sensitivity analysis showed that inflow from the river and the aquifer storage were sensitive to the specific yield and aquifer thickness. Sustainable yield was sensitive to the hydraulic conductivity and aquifer thickness. The results of this study can be used as a basic information for groundwater development and management plannings considering regional characteristics.

• Food Science of Animal Resources
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• v.33 no.2
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• pp.229-238
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• 2013

Lactic acid bacteria (LAB) are added to different food products for a long time due to health beneficial effects on human host. LAB is applied in dairy products, such as yoghurt, cheese, and various fermented products, and also in non-dairy products, such as sausages. However, reaching the human gut alive as well as in a sufficient cell amount to exert positive health effects is still a big challenge, due to LAB sensitive character and vulnerability against harsh and detrimental conditions in human digestive system. Keeping physiological activity of sensitive LAB strains alive is for the formulation of novel food products with a probiotic health claim of utmost interest, thus microencapsulation has been applied and investigated as a promising technique for a good and reliable protection. Microencapsulation allows reduced cell injury or cell loss by retaining cells within the encapsulating membrane and can be enforced by spray-drying, emulsion, extrusion, and a range of other technologies in combination with an appropriate coating material, such as alginate, chitosan, and mixture of these two polymers. In this review, established and well-studied microencapsulation techniques with their favored coating materials, as well as the recent applications of microencapsulated LAB into dairy products will be discussed.

• Food Science of Animal Resources
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• v.43 no.4
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• pp.625-638
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• 2023

Among various biological agents, bacteriocins are important candidates to control Listeria monocytogenes which is a foodborne pathogen. In this study, a novel bacteriocin, named agilicin C7, was isolated from Ligilactobacillus agilis C7 showing inhibitory activity against L. monocytogenes. Agilicin C7 biosynthesis gene was characterized by bioinformatics analyses and heterologously expressed in Escherichia coli for further study. The anti-listeria activity of recombinant agilicin C7 (r-agilicin C7) was lost by proteases and α-amylase, suggesting that agilicin C7 is a glycoprotein. r-Agilicin C7 has wide pH and thermal stability and is also stable in various organic solvents. It destroyed L. monocytogenes by damaging the integrity of the cell envelope. These properties of r-agilicin C7 indicate that agilicin C7 is a novel amylase-sensitive anti-listerial Class IId bacteriocin. Physicochemical stability and inhibitory activity against L. monocytogenes of r-agilicin C7 suggest that it can be applied to control L. monocytogenes in the food industry, including dairy and meat products.

• Food Science of Animal Resources
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• v.43 no.6
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• pp.989-1001
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• 2023

Processed foods containing pork fat tissue to improve flavor and gain economic benefit may cause severe issues for Muslims, Jews, and vegetarians. This study aimed to develop an indirect enzyme-linked immunosorbent assay (iELISA) based on a monoclonal antibody specific to thermal stable-soluble protein in pork fat tissue and apply it to detect pork fat tissue in heat-processed (autoclave, steam, roast, and fry) beef meatballs. To develop a sensitive iELISA, the optimal sample pre-cooking time, coating conditions, primary and secondary dilution time, and various buffer systems were tested. The change in the iELISA sensitivity with different 96-well microtiter microplates was confirmed. The detection limit of iELISA performed with an appropriate microplate was 0.015% (w/w) pork fat in raw and heat-treated beef. No cross-reactions to other meats or fats were shown. These results mean that the iELISA can be used as an analytical method to detect trace amounts of pork fat mixed in beef.

• Health Policy and Management
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• v.26 no.1
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• pp.4-11
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• 2016

Background: Hospital admissions for ambulatory care sensitive conditions (ACSCs), which are widely used as an indicator of poor access to primary care, can be used as an efficiency indicator of healthcare use in countries providing good access to health care. Korea, which has a national health insurance (NHI) system and a good supply of health care resources, is one such country. To quantify admission rates of ACSC and identify characteristics influencing variation in Korean health care institutions. Methods: By using NHI claims data, we computed the mean ACSC admission rate for all institutions with ACSC admissions. Results: The average ACSC admission rate for 4,461 institutions was 1.45%. Hospitals and clinics with inpatient beds showed larger variations in the ACSC admission rate (0%-87.9% and 0%-99.6%, respectively) and a higher coefficient of variation (7.96 and 2.29) than general/tertiary care hospitals (0%-19.1%, 0.85). The regression analysis results indicate that the ACSC admission rate was significantly higher for hospitals than for clinics (${\beta}=0.986$, p<0.05), and for private corporate institutions than public institutions (${\beta}=0.271$, p<0.05). Conclusion: Substantial variations in ACSC admission rates could suggest the potential problem of inefficient use of healthcare resources. Since hospitals and private corporate institutions tend to increase ACSC admission rates, future health policy should focus on these types of institutions.