• The Plant Pathology Journal
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• 제25권4호
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• pp.317-321
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• 2009

Sensitivity to the new carboxylic acid amide fungicide, mandipropamid, of Phytophthora capsici causing pepper Phytophthora blight was determined on 187 isolates collected in Korea over 3 years, from 2005 to 2007. All isolates were sensitive to mandipropamid, with $EC_{30}$ values for growth of mycelia ranging from 0.001 to $0.037\;{\mu}g/ml$. Among the isolates, 147 (79.0%) isolates were sensitive to metalaxyl, whereas others were resistant to this fungicide. Mandipropamid had the same effect on mycelium growth of both metalaxyl-sensitive and metalaxyl-resistant isolates, indicating an absence of cross-resistance between these two fungicides. Comparison of the sensitivities of P. capsici isolates showed a positive correlation between sensitivity to mandipropamid and dimethomorph ($r^2$=0.8533). The results of this study indicate that there is no evidence for development of resistance to mandipropamid in this population of P. capsici isolates collected in Korea.

• 응용통계연구
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• 제8권1호
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• pp.27-38
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• 1995

본 논문에서는 사회적으로나 개인적으로 매우 민감한 조사에서 모집단이 양적속성을 갖는 여러 개의 층으로 구성되어 있을 때, 층의 크기를 모르는 경우 층화표본을 위하여 이중추출법을 이용하는 층화이중추출법에 의한 양적속성의 무관질문모형을 제안하였다. 그리고, 층화이중추출에 있어서 각 층의 표본배분에 관해 비례배분, 최적배분으로 나누어 각 층의 크기를 알고 있는 경우에 층화추출법에 의한 양적속성의 무관 질문모형과 그 효율성을 비교하였다.

• 한국건강관리협회지
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• 제1권1호
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• pp.7-8
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• 2003

The health screening and promotion is an emerging field of clinical preventiemedicine and is proved to be effective for reduction of diseaseprevalence, particularly life-style related diseases in aged population. However, the goal of perodic health screening can be achieved by a reliable health screening that largely depond on the quality of tests. Various tests including ultrasonography, endoscopy, CT and automated blood analyzers are used in health screening. Thesescreening tests are usually sensitive, but not specific to the presence of diseases. It meams the tests produce more false positive results, that demand eztra-expenses for the confirmation of disease. Promising screening tests should be sensitive as well as specific. However, it is not easy to maintain the quality of laboratory tests, because it is affected by various factors, such as instruments, reagents, laboratory methods and human factors. This review focuses on internal and external quality control of laboratory tests and quality management of health screening services to obtain reliable test results.

• Advances in environmental research
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• 제1권1호
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• pp.57-68
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• 2012

Recent studies showed that air pollution is a risk factor for hospitalization for chronic obstructive pulmonary disease (COPD). However, there is limited evidence to suggest which subpopulations are at higher risk from air pollution. This study was undertaken to examine the modifying effect of specific secondary diagnosis (including hypertension, diabetes, pneumonia, congestive heart failure) on the relationship between hospital admissions for COPD and ambient air pollutants concentrations. Hospital admissions for COPD and ambient air pollution data for Taipei were obtained for the period from 1999-2009. The relative risk of hospital admissions for COPD was estimated using a case-crossover approach. None of the secondary diagnosis we examined showed much evidence of effect modification.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2003년도 추계학술대회
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• pp.109-110
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• 2003

To validate a novel mouse model, gpt delta, for in vivo mutagenesis, the Mammalian Mutagenesis Society (MMS), a subgroup of the Environmental Mutagen Society of Japan (JEMS) (JEMS/MMS), performed a collaborative study as the third trial for transgenic animal assay. In this mouse model, point mutations and deletions re separately identified by gpt (6-thioguanine-resistant) and Spi- (sensitive to P2 interference) selections, respectively.(omitted)

• Structural Engineering and Mechanics
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• 제60권6호
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• pp.1093-1117
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• 2016

Global sensitivity analysis (GSA) has been widely used to investigate the sensitivity of the model output with respect to its input parameters. In this paper a new single-solution search optimization algorithm is developed based on the GSA, and applied to the size optimization of truss structures. In this method the search space of the optimization is determined using the sensitivity indicator of variables. Unlike the common meta-heuristic algorithms, where all the variables are simultaneously changed in the optimization process, in this approach the sensitive variables of solution are iteratively changed more rapidly than the less sensitive ones in the search space. Comparisons of the present results with those of some previous population-based meta-heuristic algorithms demonstrate its capability, especially for decreasing the number of fitness functions evaluations, in solving the presented benchmark problems.

• Journal of applied mathematics & informatics
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• 제32권5_6호
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• pp.555-566
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• 2014

In this paper, we formulate two chemostat type models of phytoplankton and zooplankton population dynamics with instant nutrient recycling to study the role of viral infection on phytoplankton. The infection is transmitted only among phytoplankton population and it makes them more vulnerable to predation by zooplankton. It is observe that the chemostat system is very stable in the absence of viral infection but the presence of viral infection make the chemostat system sensitive with respect to the grazing rate of infected-phytoplankton by zooplankton. Further, if the grazing rate is less than certain threshold the system remain stable and exhibits Hopf-bifurcation after crossing it.

• 미생물학회지
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• 제16권4호
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• pp.161-169
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• 1978

Escherichiae-like organisms were isolated from rectal specimens of 56 children who were either in preschool age or in elementary school. The isolated strains were subjected to tests to screen enteropathogens producing heat-labile enterotoxin and susceptibility test to various antibiotics by disc diffusion method on agar plates. Production of heat-labile enterotoxin by the strains was assyed in the sensitive and reproducible cultured adrenal tumor cell system. The assay was sterodogenesis of the cell in the presence of heat-labile enterotoxin. Among 56 strains, gave positive reaction in the test of toxin production. This meant that about 10% of the children population objected to the study harbored the toxigenic strain of enteropathogenes. Some of these toxigenic strains were resistant to the antibiotics employed in the test. This study suggested that considerable population in Korea may harbor entertoxigenic E. coli as a part of intestinal normal flora. The toxigenic strains which are resistant to antibiotics may bring issue of public health in the future.

• 수면정신생리
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• 제8권1호
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• pp.11-17
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• 2001

In 2000, the number of people aged 65 and over increased to 3.37 million, accounting for 7.1% of the total population of South Korea. The elderly population will increase up to 19.3% in 2030. Sleep disordered breathing (SDB) seems to increase with age. More than 50-60% of old people complain of SDB-related signs and symptoms including awakening headache, excessive daytime sleepiness, fatigue, cognitive dysfunction, memory loss, personality changes, and depression. The influence of a mild degree of SDB upon the elderly is unclear, but moderate to severe SDB is well known to be associated with many diseases including hypertension, arrhythmia, myocardial infarction, stroke, dementia, and sudden death. Therefore, physicians should pay attention to elderly patients who complain of SDB related symptoms and signs that may not be normal signs of aging. Physicians need to become more sensitive to treat SDB in the elderly.

• Journal of Preventive Medicine and Public Health
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• 제40권2호
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• pp.122-129
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• 2007

During the last decade, genomic cohort study has been developed in many countries by linking health data and genetic data in stored samples. Genomic cohort study is expected to find key genetic components that contribute to common diseases, thereby promising great advance in genome medicine. While many countries endeavor to build biobank systems, biobank-based genome research has raised important ethical concerns including genetic privacy, confidentiality, discrimination, and informed consent. Informed consent for biobank poses an important question: whether true informed consent is possible in population-based genomic cohort research where the nature of future studies is unforeseeable when consent is obtained. Due to the sensitive character of genetic information, protecting privacy and keeping confidentiality become important topics. To minimize ethical problems and achieve scientific goals to its maximum degree, each country strives to build population-based genomic cohort research project, by organizing public consultation, trying public and expert consensus in research, and providing safeguards to protect privacy and confidentiality.