• Journal of Life Science
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• v.18 no.12
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• pp.1644-1650
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• 2008

The essential oil of tea tree (Melaleuca alternifolia) is widely used in traditional Australian medicine for skin lesions and infected injuries. In the present study, we investigated the chemical composition, cytotoxicity and its biological activities. The composition of the oil was analyzed by GC-MS. ${\beta}$-Terpinene (20.87%), ${\alpha}$-pinene (17.60%), p-cymene (11.23%), 3-carene (10.40%), trans-anethole (8.47%) and limonene (4.65%) were the major components in the oil. The results tested by MTT assay indicated that the oil showed no cytotoxic effect, at concentrations up to 5%, for less than 3h. The antiradical capacity was evaluated by measuring the scavenging activity of the essential oil on the 2,20-diphenylpicrylhydrazyl (DPPH) and 2,2'-azino-bis 3-ethyl benzothiazoline-6-sulfonic acid (ABTS) radicals. The oil was able to reduce the both radicals dose-dependently, and the concentration required for 50% reduction ($RC_{50}$) against ABTS radicals ($1.6{\pm}0.02%$) was slightly lower than DPPH radicals ($2.6{\pm}0.29%$). The direct contact and vapor-phase antibacterial activity of the oil were also evaluated using disc diffusion method against Staphylococcus aureus, Streptococcus mutans, Listeria monocytogenes, Acinetobacter baumannii, Escherichia coli, and Vibrio parahaemolyticus. All the Gram-negative bacterial strains tested showed more sensibility to the oil than the Gram-positive strains when compare to the effect of gentamycin. On the other hand, the vapor phase of the essential oil against S. aureus exhibited strongest inhibitory effect.

• Archives of Reconstructive Microsurgery
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• v.11 no.2
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• pp.153-161
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• 2002

Purpose : Plantar surfaces, calcaneal area, and region of Achilles insertion, which are extremely related with weight-bearing area and shoes application, must be reconstructed with glabrous and strong fibrous skin. Numerous methods of reconstructing defects of these regions have been advocated, but the transfer of similar local tissue as a cutaneous flap with preservation of sensory potential would best serve the functional needs of the weight-bearing and non-weight-bearing surfaces of this region. Therefore it is recommended to use the limited skin of medial surface of foot that is similar to plantar region and non-weight-bearing area. In this paper we performed the medial plantar flap transfered as a fasciocutaneous island as one alterative for moderate-sized defects of the plantar forefoot, plantar heel, and area around the ankle in 25 cases and report the result, availability and problem of medial plantar flap. Materials and methods : We performed proximally based medial plantar flap in 22 cases and reverse flow island flap in 3 cases. Average age was $36.5(4{\sim}70)$ years and female was 3 cases. The causes of soft tissue defect were crushing injury on foot 4 cases, small bony exposure at lower leg 1 case, posterior heel defect with exposure of calcaneus 8 cases, severe sore at heel 2 cases, skin necrosis after trauma on posterior foot 4 cases, and defect on insertion area of Achilles tendon 6cases. Average follow up duration was 1.8(7 months-9.5 years) years. Results: Medial plantar flaps was successful in 22 patients. 18 patients preserved cutaneous branches of medial plantar nerve had sensation on transfered flap but diminished sensation or dysesthesia. At the follow up, we found there were no skin ulceration, recurrence of defect or skin breakdown in all 18 patients. But there was one case which occurred skin ulceration postoperatively among another 4 cases not contained medial plantar nerve. At the last follow up, all patients complained diminished sensation and paresthesia at medial plantar area distally to donor site, expecially with 4 patients having severe pain and discomfort during long-time walking. Conclusion : Medial plantar island flap based on medial plantar neurovascualr pedicle have low failure rate with strong fibrous skin and preserve sensibility of flap, so that it is useful method to reconstruct the skin and soft tissue defect of foot. But it should be emphasized that there are some complications such like pain and paresthesia by neuropraxia or injury of medial plantar nerve at more distal area than donor site. We may consider that medial plantar flap have limited flap size and small arc of rotation, and require skin graft closure of the donor defect and must chose this flap deliberately.

• The Journal of Internal Korean Medicine
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• v.26 no.1
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• pp.74-92
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• 2005

Objectives/Methods : To analyze the effect of Injinchunggantang(IJCGT) to Interferon-${\alpha}/{\beta}$ signal transmission system in HepG2 cells, HepG2 Cell were treated with IJCGT. Also, revelation of MxA, 2'5'-OAS mRNA leaded by Interferon-${\alpha}/{\beta}$ and revelation and activation of Jak1, TYK1, and STAT 1, all main signal transmission factors, were analyzed. Results : The analysis resulted in the following 1. With interferon ${\alpha}/{\beta}$ there was no affect cell propagation of Hep G2 cells. With IJCGT alone, cell propagation of HepG2 was promoted, and cell propagation control function was recovered. 2. With interferon ${\alpha}/{\beta}$ cell death was unaffected. With IJCGT apoptosis of HepG2 cell was restrained, and the cell's reaction to interferon was unaffected. 3. With interferon ${\alpha}/{\beta}$ treatment mRNA revelation of MxA and 2'5'-OAS was induced. When HepG2 cells were injected with IJCGT without interferon ${\alpha}/{\beta}$ treatment, mRNA revelation of MxA and 2'5'-OAS increased in proportion to the treatment density. With pre-treatment of IJCGT, leaded with interferon ${\alpha}/{\beta}$, promoted revelation of MxA, 2'5' -OAS mRNA. 4. Though mRNA revelation of lakl, TYK1 and STAT1 was unaffected with IJCGT, activation of STAT1 was promoted with an increase of phosphorylation of STAT1 protein. With pre-treatment of IJCGT, Jak1, TYK2, STAT1 phosphorylation, leaded with interferon, strengthened. 5. TNF-a, IL-1b and LPS present, revelation of MxA and 2'5'-OAS mRNA leaded by interferon was restrained when HepG2 cells were treated with IJCGT, and the interferon signal transmission system restraint action leaded by inflammatory cytokines was moderated. Conclusion : These results support a role for IJGCT in promotion of anti-virus action through maintainance of the liver's sensibility toward interferon. A clinical study of an interferon treated patient treated also with IJGCT is needed to determine its efficacy.

• Magazine of the Korean Society of Agricultural Engineers
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• v.16 no.2
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• pp.3420-3429
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• 1974

This study was performed to estimate the daily water consumption for watering livestock and home use, and to organize the water systems in the rural districts of Korea. For these purposes, 560 farms and other 40 urban families were randomly chosen and investigated about their water systems and daily water consumption seasonally from July 20 to August 31, 1973, and other 82 livestock raisers' useful data for watering livestock helped the study to assess the consumption of livestock water and compare it to that of general farms which bred some domestic animals as their sidelines. The results of data showed that the daily consumption of water was varied with the difference of districts and seasons in which the investigations were conducted. The results were summarized as follows. 1. The mean consumption of water for home use was varied with the range of 30.2-48.7 lit./day in summer and 22.4-45.2 lit./day per a person, respectively, in the rural districts, which showed that the water consumption in summer was more than in autumn. 2. The mean consumption of livestock water in the general farms approached to about 15.8-37.1 lit./day per cattle, 3.87-16.45 lit./day per a pig, and 0.19-1.03 lit./day per chicken, but it was slightly reduced in autumn; 10.89-37.09 lit./day per cattle, 3.87-12.63 lit./day per a pig, and 0.06-0.94 lit./day per chicken. The ratio of livestock water consumption to home use amounted to the range of 10-25%. 3. The mean consumption of livestock water used at the livestock raisers amounted to 134 lit./day per dairy cow, 67.4 lit./day per cattle, 43.29 lit./day per a horse, 13.24 lit./day per a pig, 0.438 lit./day per a layer, and 0.177 lit./day per a broiler, which showed that the daily water consumption for larger livestock was about two times as much as the farms, but it was approximately of the same for small ones. 4. The factors affecting the amount of water consumption for home use were statistically analyzed to find the kind of water sources and the class of water systems by the factorial arrangement method to the fundamental experimental unit, Suwon area of 100 of families, in which the former was very significant while the latter was significant. However, the standard of living and their interactions were not significant. 5. Almost 83.24% of the sampled farms used some kinds of wells as their water sources, of which 32.06% was of hard water, and of which 11.l% or 2.6% contained much of iron or organice materials, respectively, examining them by a simple technique of sensibility, 6. The resulting chart of the farm water systems was summarized as Fig. IV-6. Observating the safe distance from contamination sources, the ratio of 42.4% of sampled farms whose water sources were wells, confronted highly to the danger of contamination to their water sources. And other dangerous sources of contamination such as toilets, stalls, and compost heaps were situated nearly to the water sources, and most of them were able to make their spoiled water infiltrated into the ground. Thereafter, it was recommended to develop some protecting methods and to install some suitable faculties to clean water.

• Journal of the Korean association of regional geographers
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• v.19 no.4
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• pp.615-626
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• 2013

In this study, spatial patterns of the urban flood vulnerability index in Seoul are examined by considering climate exposure, sensitivity, and adaptability associated with floodings for recent 5 year (2006~2010) period by the smallest administrative unit called Dong. According to the results of correlation analyses based on the IPCC(Intergovernmental Panel on Climate Change)'s vulnerability model, among many variables associated with urban flooding, rainwater tank capacity, 1-day maximum precipitation and flood pumping station capacity have statistically-significant, and relatively-high correlations with the number of flood damage in Seoul. The flood vulnerability map demonstrates that the extensive areas along Anyang and Joongnang streams show relatively high flood vulnerability in Seoul due to high sensitivity. Especially in case of Joongnang stream areas, climatic factors also contribute to the increase of flood vulnerability. At local scales, several Dong areas in Gangdong-gu and Songpa-gu also show high flood vulnerability due to low adaptability, while those in Gangnam-gu do due to high sensibility and climate factor such as extreme rainfall events. These results derived from the flood vulnerability map by Dong unit can be utilized as primary data in establishing the adaptation, management and proactive policies for flooding prevention within the urban areas in more detail.

• The Journal of the Korea Contents Association
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• v.13 no.10
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• pp.480-494
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• 2013

Globally branded culture festival in the region as a key component to the originality and distinction and with local residents and visitors to share experience and has succeeded in branding through Mind. Than mimics festivals in competitive and differentiated cultures containing festivals create a unique festival brand, and through the cultural and economic competitiveness, as well as the phase of the World Festival and preserve local culture and identity. Developing The best areas will be an asset. In order to build this world-class festival brand differentiation strategy above all, must be a top priority, Discrimination discovery and development of the local culture and sensibility in the age of the most powerful marketing tool that is being presented through storytelling brand assets to be passed on to visitors should. Thus the creation of storytelling festivals. Sensitivity of the festival right direction and in an era of paradigm key drivers of the local economy, such as image enhancement, and building long-term regional development and differentiation based on quality of life by creating a local culture can improve will Region's cultural and economic areas, the most important resource for the success of the festival is uniformly short-term planning and configuration, tube-driven operating as a one-sided non-participation. Sharing. Communication with an emphasis on the application of storytelling that is essential is considered.

• The Journal of the Korea Contents Association
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• v.20 no.3
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• pp.356-369
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• 2020

Farm village business performance may be influenced by village leader's leadership and conflict management between villagers, so the objective of this study is to analyze the relationships among farm village leader's leadership, conflict management between villagers and farm village business performance. The questionnaire was performed for 376 villagers in Jeollabuk-do Province. The collected data was analyzed by structural equation model and Sobel test. The result shows that farm village leader's leadership such as human-relationship ability, management ability, communication skills, and industrial knowledge ability have statistically significant positive effects on the conflict management between villagers. The conflict management between villagers also showed a statistically significant positive effects on the social and economic performance. The farm village leader's leadership such as human-relationship ability, sensibility·awareness ability, management ability, communication skills, industrial knowledge ability showed no statistically significant effects on the social and economic performance. But, they showed a statistically significant effects on the farm village business performance in indirect manner with the mediating effect of the conflict management between villagers. It is worthwhile that in this study, the effect of village leader's leadership on the conflict management between villagers and farm village business performance was verified, and then, it is meaningful to present the role and importance of farm village leader's leadership.

• Journal of Gifted/Talented Education
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• v.26 no.1
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• pp.77-99
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• 2016

The purpose of this study was to examine the effect of GI-STEAM program on leadership, creative personality, and learning flow of elementary Gifted Students. GI-STEAM program was the convergence model of Group Investigation that belongs to Co-learning and STEAM framework of learning criterion. The participants were 16 gifted students in a Korean elementary school located in Gyeong-gi province. The experimental design was one group pretest-posttest design. After a pretest on leadership, creative personality, and learning flow was conducted, classes were carried out as GI-STEAM program for the gifted student and a post-test was conducted. The study results of the class that was conducted twelve times for two weeks are as follows. First, Individual area of leadership is meaningfully developed in statistics after GI-STEAM program. The sub-domains of leadership, such as the communication, organization management, society commitment and teamwork showed a statistically significant improvement. Second, the domain of creative personality didn't show meaningful difference after GI-STEAM program. However, the aesthetic in the sub-domains of the creative personality showed a statistically significant improvement. Third, learning flow was meaningfully developed in statistics after GI-STEAM program. The sub-domains of the leadership, such as the balance between challenge and ability, integration with behavior and consciousness, concrete feedback and Autotelic experience showed a statistically significant improvement. In conclusion, GI-STEAM is an effective program for improving ability of communication, aesthetic sensibility, which are core competency of 'creative-convergence' gifted students. For this reason, it is highly considered that various programs applying GI-STEAM should be developed.

• Journal of Digital Convergence
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• v.16 no.7
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• pp.223-229
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• 2018

Recently, the necessity of safety diagnosis of electrical devices has been increasing as the fire caused by electric devices has increased rapidly. This study is concerned with the safety diagnosis of electric equipment using intelligent Fuzzy technology. It is used as a diagnostic input for the multiple electrical safety factors such as the use current, cumulative use time, deterioration and arc characteristics inherent to the equipment. In order to extract these information in real time, a device composed of various sensor circuits, DSP signal processing, and communication circuit is implemented. The fuzzy logic algorithm using the Gaussian function for each information is designed and compiled to be implemented on a small DSP board. The fuzzy logic receives the four diagnostic information, deduces it by the fuzzy engine, and outputs the overall safety status of the device as a 100-step analog fuzzy value familiar to human sensibility. By experiments of a device that combines hardware and fuzzy algorithm implemented in this study, it is verified that it can be implemented in a small DSP board with human-friendly fuzzy value, diagnosing real-time safety conditions during operation of electric equipment. In the future, we expect to be able to study more intelligent diagnostic systems based on artificial intelligent with AI dedicated Micom.

• The Journal of the Convergence on Culture Technology
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• v.6 no.1
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• pp.31-36
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• 2020

Corporate Culture Marketing is a marketing tool that enhances a company's cultural image or conveys its image through culture. Culture Consumer value analysis is important predictive data in identifying the value and pursuit of life in individual consumption behavior, explaining the choice behavior of culture consumers, and serves as the basis for decision making. The research method was linked to the text mining and opinion mining techniques of big data, and extracted positive, negative and neutral words. The analysis targets culture consumers participating in concerts at Hyundai Card's 'Super Concert', which is subject to domestic consumers, and CJ ENM's 'KCON', which is subject to foreign consumers. The culture consumer value elements of corporate culture marketing are the basic conditions, and they were derived as 'Consensus Communication (Expression of Sensibility)', 'Participation Sharing(VIP Belonging)', 'Social Change Issue', 'Differentiating Services', 'Price Discount Benefit' and 'Location Quality'. In the future, we will need to foster 'Culture Technology Marketers' and apply them in areas such as arts management planning, cultural investment, cultural distribution, cultural space, Corporate Culture, CSR and K-pop marketing to enhance corporate interests and brand value and enhance brand value.