• 한국동물번식학회:학술대회논문집
• /
• 한국동물번식학회 2003년도 학술발표대회 발표논문초록집
• /
• pp.80-80
• /
• 2003

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor, cognitive, and psychiatric symptoms, accompanied by marked cell death in the striatum and cortex. Stereotaxic injection of quinolinic acid (QA) into striatum results in a degeneration of GABAergic neurons and exhibits abnormal motor behaviors typical of the illness. The objective of this study was carried out to obtain basic information about whether parthenogenetic mouse embryonic stem (PmES) cells are suitable for cell replacement therapy of HD. To establish PmES cell lines, hybrid F1 (C57BL/6xCBA/N) mouse oocytes were treated with 7% ethanol for 5 min and cytochalasin-B for 4 hr to initiate spontaneous cleavage. Thus established PmES cells were induced to differentiate using bFGF (20ng/ml) followed by selection of neuronal precursor cells for 8 days in N2 medium. After selection, cells were expanded at the presence of bFGF (20 ng/ml) for another 6 days, then a final differentiation step in N2 medium for 7 days. To establish recipient animal models of HD, young adult mice (7 weeks age ICR mice) were lesioned unilaterally with a stereotaxic injection of QA (60 nM) into the striatum and the rotational behavior of the animals was tested using apomorphine (0.1mg/kg, IP) 7 days after the induction of lesion. Animals rotating more than 120 turns per hour were selected and the differentiated PmES cells (1$\times$10$^4$cells/ul) were implanted into striatum. Four weeks after the graft, immunohistochemical studies revealed the presence of cells reactive to anti-NeuN antibody. However, only a slight improvement of motor behavior was observed. By Nissl staining, cell mass resembling tumor was found at the graft site and near cortex which may explain the slight behavioral improvement. Detailed experiment on cell viability, differentiation and migration explanted in vivo is currently being studied.

• 동아시아식생활학회지
• /
• 제24권1호
• /
• pp.12-19
• /
• 2014

The purpose of this research was to study the affects of atmosphere and convenience attributes on restaurant selection of customers aged between 50 to 60, referred to as new seniors. A survey was conducted with questions including convenience and atmosphere attributes (5 factors, 24 questions), respondents' dining-out behavior (6 questions), and general characteristics. For the analysis, SPSS 20.0 was used for the frequency analysis, factor analysis and ANOVA. The findings of this research are as follows : First, new seniors considered cleanliness (4.23) as the most important factor when choosing a restaurant. Convenient facility (3.89), ease of use (3.68), atmosphere (3.33) and children amenities (3.18) followed. Second, the importance of factors were compared according to the general characteristics. Based on gender, cleanliness and convenient facility showed a significant difference (p<0.05). Depending on whether they help raise their grandchildren and household type, the difference of ease of use and children amenities showed significance (p<0.05). Third, the importance of factors were compared based on their dining-out behavior. According to the average visits made to restaurants and the average payment per person, the difference of cleanliness and ease of use factors showed a significant difference (p<0.05). In addition, there were significant differences (p<0.05) on convenient facility and atmosphere factor depending on the average payment per person. The results of this research hopes to provide useful information to marketers targeting new seniors.

• 한국의류산업학회지
• /
• 제19권4호
• /
• pp.468-478
• /
• 2017

The purpose of this study is to examine the differences in appearance management behaviors and demographic variables among groups classified by the appearance management motives. The questionaries are administerd to 493 female and male adults above 20 years old in Seoul, Kyeonggi-do, Daegu and Kyungpook regions. For analysis of data from 478 respondents, descriptive statistics, factor analysis, cluster analysis, Cronbach's ${\alpha}$, ANOVA, Duncan test and ${\chi}^2$ test were applied. We show the following results: First, factor analysis for appearance management motives extracted three factors such as self-development, emphasis on the trendy appearance, and sexual appealing motive. Factor analysis for appearance management behaviors extracted four factors such as weight training, surgery/skin care, hair care and clothing selection. Second, three groups of the appearance management motives were classified into such as the social self-management type, the sexual appealing self-management type, the passive appearance management type. The social self-management groups are more interested in self-development, emphasis on the trendy appearance, and sexual appealing motive. And they are also more involved in appearance management behaviors: clothing selection is the most pursuing appearance management behavior. Third, among the demographic variables, the single and female in 20s and 30s with higher level of education belonged to the social self-management group. In this contribution, we find significant differences in the appearance management behavior and demographic variables classified by the appearance management motives.

• 한국정보과학회논문지:정보통신
• /
• 제33권2호
• /
• pp.183-192
• /
• 2006

이 논문은 QoS (Quality of Service) 네트워크 서비스를 위한 우선순위 방식의 스케줄링에서, 각 서비스 레벨의 가격을 정하는 문제를 분석한다. 특히 본 논문에서는 균형 분석 (equilibrium analysis)에 근거한 가격정책의 문제점을 파악하는 것에 중점을 둔다. 균형분석은 다음과 같은 두 가정하에 이루어진다. 첫째, 각각의 사용자들이 시스템 전체에 미치는 영향은 극히 미약하여 무시할 수 있다. 둘째, 사용자들은 전체 시스템 상태에 대한 최신의 정보를 알고 있다. 그러나 이러한 가정들은 실제 상황을 정확하게 반영하지 못하는 경우가 종종 있고, 따라서 균형분석에 의한 가격의 결정은 문제점이 있다고 본다. 본 논문에서는 시스템 작동상황을 분석하기 위해 '동적모델'을 개발하고, 이를 이용하여 현존하는 균형분석 방법의 정확성을 평가하였다. 연구결과에 의하면 균형분석은 실제적인 환경에서의 시스템의 작동 현황을 정확하게 반영하지 못하는 경우가 많은 것으로 나타났다.

• 대한지역사회영양학회지
• /
• 제6권5호
• /
• pp.755-764
• /
• 2001

This study was carried out to evaluate meal management behavior of housewives and to improve their behavior by determining what problems exist. The survey was conducted using a questionnaire in Jinju from October to November in 1999. It was shown that 29.1% of housewives didn't plan food budget, whereas only 5.6% of them did. The reasons for not planning food budget were mostly due to not forming a habit(38.8%), irregularity of prices(19.9%) or irregularity of income(13.8%). The characters of planning food budget and the reasons for not planning were not affected by age, education, monthly income, family size or monthly flood cost. Only 17.8% of meal managers recorded their housekeeping in detail and 47.4% of them wrote only the important things. Recording housekeeping records was affected by age and education. It was found that most meal managers(90.8%) didn't set menu planning and they didn't fuel the need for menu planning. The frequency of food shopping was every two days(36.2%), twice a week(20.9%) or randomly(27.4%), and the places for food shopping were supermarket(49.0%) and traditional market(41.3%). Both were affected by education or age. The quality of food was the main reason(54.6%) far the selection of food shopping place. Important consideration for selection of food and meals was preference of family(47.4%) and this character was affected by education. It was shown that the score of nutrition knowledge was 7.36, and it was affected by education. The results of this study suggest that the government, educators and scientists in nutrition make efforts to develop various levels of practical education programs for meal management and nutrition depending on age, education and community using mass media.

• 한국의류학회지
• /
• 제39권2호
• /
• pp.294-306
• /
• 2015

This study investigated how the travel motivation of Korean overseas tourists influenced shopping behavior. We first identified factors of the travel motivation and then categorized types and attributes of shopping products and shopping stores. We then examined the relationship between the travel motivation and shopping products and shopping channels. A questionnaire method was applied for this survey, while factor analysis and regression analysis were used to analyze data. The results are listed below. First, nature & leisure, rest, family, pleasure, hobby & fitness, and discovery were identified as 6 factors of travel motivation. Second, shopping products of overseas tourists were categorized into three types: fashion & luxury, daily goods, and memento. There were four attributes of products, namely, design, utility, economy, and prestige. Major types of shopping stores were souvenir shops, fashion channels and local markets; the shopping store attributes identified were location & salesperson, assortment & atmosphere, and display. Third, overseas tourists' motivation was shown to influence the selection of product types and attributes. Those who traveled for rest, family, pleasure, hobby & fitness orientation were inclined to purchase fashion & luxury goods, and daily goods; however, those who traveled for rest and hobby & fitness orientation also tended to buy memento. The effect of the travel motivation was shown to be different according to product attributes. Fourth, tourists' motivation was shown to affect store type selection and attributes. Those whose traveled for rest, family, pleasure, hobby & fitness preferred souvenir shops while those seeking nature & leisure and pleasure tended to visit fashion channels and local markets more often. Travelers seeking nature & leisure and discovery cared for all three store attributes while family oriented and pleasure seeking tourists considered shopping store location, salesperson and display attributes as important.

• 한국조리학회지
• /
• 제22권5호
• /
• pp.106-116
• /
• 2016

본 연구에서는 노년층의 라이프스타일이 프랜차이즈 레스토랑의 선택속성이 얼마나 영향을 끼치는지 측정하였다. 그리고 구전의도가 노년층의 라이프스타일과 프랜차이즈 레스토랑의 선택속성 사이에서 어떤 영향을 끼치는지 측정하였다. 연구 결과, 첫째, 노년층들의 라이프스타일의 하위변수인 외향적, 개방형, 진보형, 미래 지향형 활동 4가지를 변수로 설정하였다. 그 결과, 외향적(${\beta}=.463$, p<.001), 개방형(${\beta}=.132$, p<.001), 진보형(${\beta}=.150$, p<.001), 미래지향적(${\beta}=.320$, p<.001)로 종속변수인 프랜차이즈 레스토랑의 선택속성에 대하여 모두 유의한 정(+)의 영향관계가 있는 것으로 분석되었다. 둘째, 조절변수인 구전의도가 추가된 2단계 모형에서는 구전의도의 추가로 인한 설명력의 증가는 0.1%이고, 이에 대한 F=147.556(p<0.01)로 설명력의 증가로 2단계 역시 유의적으로 나왔다. 조절효과를 검증하는 상호작용항들이 추가로 들어간 3단계에서는 '노년의 라이프스타일${\times}$구전의도'의 추가적인 투입으로 인한 설명력의 증가는 0.5%이고, 이에 대한 F=82.987(p<0.01)로 조절효과는 유의적으로 나왔다. 노년의 라이프스타일과 구전의도의 개별적인 조절효과를 보면 미래적${\times}$구전의도는 유의적인 정(+)의 영향력이 있었고, 또한 외향적${\times}$구전의도는 유의적인 부(-)의 영향력이 있었다.

• 대한간호학회지
• /
• 제16권2호
• /
• pp.44-52
• /
• 1986

Maternal and child health(MCH) status is considered as an important indicator of the level of health and civilization of a community and a country. MCH services for the rural population in the remote ar deserves priority by the government, since more than half(52.9%) of the delivery was occured at home and almost half (45.5%) of the delivery was assited by family members or neighbors. The purpose of the study was to analyse the health fare behavior related to pregnancy and delivery, which can be contributed maternal health care policy mating for the rural people. Specifically, it was intended to analyze the variables which affect the health care behavior in selecting birth places and birth attendants. This study utilized the data which had been already collected for an experimental study on primary health program model in Korean rural communities, funded by the USAID. 184 sample households with women who had delivered a baby during March 1982 to February 1983 were selected. Discriminant Analysis was employed for statistical analysis by utilizing SPSS computer package program. Birth places and birth attendants were considered as dependent variables. Among 12 independent variables in 5 groups considered, 7 independent variables were found statistically significant to affect the selection of birth place. Significant variables by the order of importance are mother's age, order of baby, number of prenatal care, accessibility of emergency medical care, coverage of medical insurance, mother's membership in community organization and husband's educational level. The degree of correct classification of the grouped cases by employing a discriminant . analysis was significantly improved to 78.2％ in comparison to Cmax（56%) and Cpro(51%). Policy implications for each significant variable were discussed to improve the maternal and child health. in Korean ruralarea.

• 한국문헌정보학회지
• /
• 제50권1호
• /
• pp.71-99
• /
• 2016

본 연구는 이용자들의 불확실성과 관련된 정보추구행태를 조사하였다. KERIS 에듀넷 시스템을 활용하여 국사 영역의 정보를 탐색하는 이용자집단을 대상으로 자료수집이 이루어졌고, 수집된 자료는 근거이론의 지속적인 비교분석에 의해 분석되었다. 연구결과는 정보요구의 식별, 정보시스템의 선정, 탐색어의 선택, 정보시스템의 이용 및 탐색결과의 평가 등 다섯 단계에 걸친 이용자 불확실성을 제시하였다. 에듀넷 시스템 및 관련 서비스의 제고로 나누어 제시된 본 연구의 제안점은 다음과 같이 요약될 수 있다. 시스템 측면에서는 탐색 및 디스플레이 인터페이스 기능을 포함한 검색 메커니즘의 개선, 그리고 지원하는 자료의 확충으로 정리되었다. 서비스 측면에서는 정보서비스 제공자가 '불확실성의 근원'(origin of uncertainty)을 파악함이 중요하다는 점이 강조되었다. 즉 '근원'이 시스템 기능의 미흡함과 관련되어 있는지, 아니면 특정 이용자의 탐색경험 부족 또는 탐색능력 미비에만 기초한 것인지를 파악할 필요성을 제시하였다. 즉 제반 요인들을 고려한 정보서비스 제공자의 개입이 요구됨을 강조하였다.

• 한국산학기술학회논문지
• /
• 제13권8호
• /
• pp.3597-3609
• /
• 2012

본 연구는 청소년이 접근할 수 있는 중독행동을 포괄적으로 측정할 수 있는 다차원적 중독행동 측정도구를 개발하고 신뢰도와 타당도를 검정함으로써, 청소년 중독행동에 대한 포괄적인 사정과 다차원적 접근을 위한 기초자료를 제시하고자 시행되었다. 본 연구는 개념적 기틀형성, 초기문항 작성, 내용타당도 검정, 2차 문항 작성 및 최종문항 확정의 과정으로 진행되었다. 대상자는 636명의 중고등학생인 청소년이었고, 자료는 자가보고 질문지로 수집되었다. 자료분석은 SPSS 19.0 프로그램을 이용하였다. 청소년의 중독행동은 총 70문항이 최종문항으로 선정되었으며, 게임 중독행동, 쇼핑 중독행동, 휴대폰 중독행동, 니코틴 중독행동, 텔레비전 중독행동, 도박 중독행동, 인터넷 중독행동, 알코올 중독행동의 8개의 하부요인이 분류되었고, 이에 대한 설명변량은 56.6%이었다. 청소년 중독행동은 중독성과 자기통제와 유의한 순상관이 있었으며, 신뢰도인 Cronbach's alpha가 .94이었다. 또한 중동행동의 선별기준이 일반군, 중독행동 위험군, 중독행동군으로 분류되었다. 청소년의 중독행동을 정확하게 파악하여 효과적인 교육 및 지도를 위한 방안을 마련하고, 청소년의 중독을 조기에 발견하여 적절한 관리를 시작하게 함으로써 청소년의 신체적 정신적 건강증진을 위한 교육과 연구 및 실무에 기여할 것이다.