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Bioactive compounds in food for age-associated cognitive decline: A systematic review (인지기능 개선을 위한 식품유래 생리활성소재에 대한 체계적 문헌고찰)

  • Kang, Eun Young;Cui, Fengjiao;Kim, Hyun Kyung;Go, Gwang-woong
    • Korean Journal of Food Science and Technology
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    • v.53 no.3
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    • pp.278-289
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    • 2021
  • The rapid aging of society has led to a surge in cognitive dysfunction in the elderly. As there is limited evidence for the development of dementia in medicine, a shift in focus on prevention strategies using bioactive compounds in food is required. This systematic review evaluated the effects of various bioactive compounds on age-associated cognitive decline. The literature was searched for terms related to bioactive compounds in cognitive decline and article selection was limited to clinical randomized controlled trials for a single bioactive compound. We identified 21 studies that evaluated the strength of the evidence. ω-3 fatty acids and vitamin B presented a strong evidence level, whereas vitamin D and E, anserine/carnosine, and chromium were defined as having moderate levels of evidence. ω-3 fatty acids relieved cognitive decline and reduced amyloid β-related protein accumulation. Vitamin B decreased homocysteine levels, which is accompanied by alleviation of cognitive function. In conclusion, ω-3 and vitamin B have the potential to improve age-associated cognitive decline.

A Study on the Level of Citizen Participation in Smart City Project (스마트도시사업 단계별 시민참여 수준 진단에 관한 연구)

  • PARK, Ji-Ho;PARK, Joung-Woo;NAM, Kwang-Woo
    • Journal of the Korean Association of Geographic Information Studies
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    • v.24 no.2
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    • pp.12-28
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    • 2021
  • Based on the global smart city promotion trend, in 2018, the "Fourth Industrial Revolution Committee" selected "sustainability" and "people-centered" as keywords in relation to the direction of domestic smart city policy. Accordingly, the Living Lab program, which is an active citizen-centered innovation methodology, is applied to each stage of the domestic smart city construction project. Through the Living Lab program, and in collaboration with the public and experts, the smart city discovers local issues as it focuses on citizens, devises solutions to sustainable urban problems, and formulates a regional development plan that reflects the needs of citizens. However, compared to citizen participation in urban regeneration projects that have been operated for a relatively long time, participation in smart city projects was found to significantly differ in level and sustainability. Therefore, this study conducted a comparative analysis of the characteristics of citizen participation at each stage of an urban regeneration project and, based on Arnstein's "Participation Ladder" model, examined the level of citizen participation activities in the Living Lab program carried out in a smart city commercial area from 2018 to 2019. The results indicated that citizen participation activities in the Living Lab conducted in the smart city project had a great influence on selecting smart city services, which fit the needs of local residents, and on determining the technological level of services appropriate to the region based on a relatively high level of authority, such as selection of smart city services or composition of solutions. However, most of the citizen participation activities were halted after the project's completion due to the one-off recruitment of citizen participation groups for the smart city construction project only. On the other hand, citizens' participation activities in the field of urban regeneration were focused on local communities, and continuous operation and management measures were being drawn from the project planning stage to the operation stage after the project was completed. This study presented a plan to revitalize citizen participation for the realization of a more sustainable smart city through a comparison of the characteristics and an examination of the level of citizen participation in such urban regeneration and smart city projects.

Selection of Rice Varieties for Production of High Quality Rice in Southern Area of Korea (남부 주요 지역별 고품질 쌀 생산을 위한 적정 품종 선발)

  • Seong, Deok-Gyeong;Jin, Young-Min;Kim, Young-Gwang;Joung, Wan-Kyu;Kim, Cheol Soo;Chung, Jung-Sung
    • Journal of agriculture & life science
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    • v.53 no.2
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    • pp.87-95
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    • 2019
  • This study was carried out to select the rice variety for high quality rice according to reducing N application level (7 kg/10 a) in medium altitude and plain of southern Korea. It was cultivated to seven varieties and ten varieties in medium altitude and plain region respectively in this study. In medium altitude region, the yield of head rice was higher in most varieties except for Borami (526 kg/10 a) than the control variety, Chucheongbyeo (533 kg/10 a). On the other hand, Borami, Gopumbyeo, and onnuri were lower in head rice rate than the other varieties. In addition, Borami and Chucheongbyeo shown a lodging risk but the other varieties were safe against lodging. The milled rice protein content of Chucheongbyeo was 6.1% and the other varieties protein content was similar or lower than that of control except for Borami(6.3%). In plain region, the head rice yield of Nampyeongbyeo (527 kg/10 a) was higher than that of control variety, Ilmibyeo (503 kg/10 a). Head rice rate was lower in Hopumbyoe, Sindongjin, and Chilbobyeo than the other varieties. The varieties contained lower protein content compared Ilmibyeo (6.1%) were Hopumbyeo (5.9%), Jinsumi (6.0%), Sindongjin (5.9%), Chilbobyeo (6.0%), Hwangeumnodeul (5.8%), Hopyeongbyeo (6.0%). Amylose content, whiteness, and palatability (Toyo value) were no significant difference among varieties in two different regions. In conclusion, considering head rice rate, yield of head rice, protein content, lodging resistance, ripening rate and palatability, Pungmi1ho, Saenuri, Chilbobyeo in medium altitude region and Jinsumi, Hwanggumnodul in plain region were selected as proper rice varieties for high quality rice production in southern Korea.

Estimation of Genetic Parameters for Growth and Egg Production Traits in Black Korean Native Chicken and Korean White Leghorn Populations (흑색한국재래닭, 한국화이트레그혼 집단의 산육 및 산란 형질 유전모수 추정)

  • Cha, Jaebeom;Kim, Kigon;Choo, Hyojun;Kwon, Il;Park, Byeongho
    • Korean Journal of Poultry Science
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    • v.47 no.4
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    • pp.267-274
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    • 2020
  • This study was conducted to estimate genetic parameters for growth and egg production traits in Black Korean native chicken (L strain) and Korean White Leghorn (F, K strains) using a multi-traits animal model BLUP. Traits used for this study were body weight at 150 days (BW150) and 270 days (BW270), age at first egg (DAY1st), egg weight at first egg (EW1st) and 270 days (EW270), and number of eggs laid by 270 days (EP270), and included 68,688 pedigree and 123,905 performance records collected from 2001 to 2013. In L, F, K strains, heritability estimates of BW150 were high (0.48, 0.52 and 0.50, respectively); of BW270 were high (0.56, 0.57 and 0.56); of DAY1st were medium to high (0.45, 0.39 and 0.31); of EW1st were low (0.15, 0.16 and 0.15); of EW270 were high (0.58, 0.55 and 0.59) and of EP270 were moderate (0.22, 0.21 and 0.20). The genetic and phenotypic correlation of DAY1st with EP270 were highly negative (-0.73 to -0.63 and -0.48 to -0.42). The genetic and phenotypic correlation of EP270 with BW150 and BW270, respectively were low negative (-0.16 to 0.01 and -0.14 to -0.03) and low to moderate positive (-0.08 to 0.07 and -0.13 to 0.04). The genetic and phenotypic correlation of EW270 with BW150 and BW270, respectively were moderate to high positive (0.39 to 0.49 and 0.36 to 0.46) and (0.29 to 0.33 and 0.34 to 0.37). The study showed that there is a potential for genetic improvement of Korean Indigenous chicken through selection program.

Spectral Band Selection for Detecting Fire Blight Disease in Pear Trees by Narrowband Hyperspectral Imagery (초분광 이미지를 이용한 배나무 화상병에 대한 최적 분광 밴드 선정)

  • Kang, Ye-Seong;Park, Jun-Woo;Jang, Si-Hyeong;Song, Hye-Young;Kang, Kyung-Suk;Ryu, Chan-Seok;Kim, Seong-Heon;Jun, Sae-Rom;Kang, Tae-Hwan;Kim, Gul-Hwan
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.23 no.1
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    • pp.15-33
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    • 2021
  • In this study, the possibility of discriminating Fire blight (FB) infection tested using the hyperspectral imagery. The reflectance of healthy and infected leaves and branches was acquired with 5 nm of full width at high maximum (FWHM) and then it was standardized to 10 nm, 25 nm, 50 nm, and 80 nm of FWHM. The standardized samples were divided into training and test sets at ratios of 7:3, 5:5 and 3:7 to find the optimal bands of FWHM by the decision tree analysis. Classification accuracy was evaluated using overall accuracy (OA) and kappa coefficient (KC). The hyperspectral reflectance of infected leaves and branches was significantly lower than those of healthy green, red-edge (RE) and near infrared (NIR) regions. The bands selected for the first node were generally 750 and 800 nm; these were used to identify the infection of leaves and branches, respectively. The accuracy of the classifier was higher in the 7:3 ratio. Four bands with 50 nm of FWHM (450, 650, 750, and 950 nm) might be reasonable because the difference in the recalculated accuracy between 8 bands with 10 nm of FWHM (440, 580, 640, 660, 680, 710, 730, and 740 nm) and 4 bands was only 1.8% for OA and 4.1% for KC, respectively. Finally, adding two bands (550 nm and 800 nm with 25 nm of FWHM) in four bands with 50 nm of FWHM have been proposed to improve the usability of multispectral image sensors with performing various roles in agriculture as well as detecting FB with other combinations of spectral bands.

Prediction Study on Major Movement Paths of Otters in the Ansim-wetland Using EN-Simulator (EN-Simulator를 활용한 안심습지 일원 수달의 주요 이동경로 예측 연구)

  • Shin, Gee-Hoon;Seo, Bo-Yong;Rho, Paikho;Kim, Ji-Young;Han, Sung-Yong
    • Journal of Environmental Impact Assessment
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    • v.30 no.1
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    • pp.13-23
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    • 2021
  • In this study, we performed a Random Walker analysis to predict the Major Movement Paths of otters. The scope of the research was a simulation analysis with a radius of 7.5 km set as the final range centered on the Ansim-wetland in Daegu City, and a field survey was used to verify the model. The number of virtual otters was set to 1,000, the number of moving steps was set to 1,000 steps per grid, and simulations were performed on a total of 841 grids. As a result of the analysis, an average of 147.6 objects arrived at the boundary point under the condition of an interval of 50 m. As a result of the simulation verification, 8 points (13.1%) were found in the area where the movement probability was very high, and 9 points (14.8%) were found in the area where the movement probability was high. On the other hand, in areas with low movement paths probabilities, there were 8 points (13.1%) in low areas and 4 points (6.6%) in very low areas. Simulation verification results In areas with high otter values, the actual otter format probability was particularly high. In addition, as a result of investigating the correlation with the otter appearance point according to the unit area of the evaluation star of the movement probability, it seems that 6.8 traces were found per unit area in the area where the movement probability is the highest. In areas where the probability of movement is low, analysis was performed at 0.1 points. On the side where otters use the major movement paths of the river area, the normal level was exceeded, and as a result, in the area, 23 (63.9%), many form traces were found, along the major movement paths of the simulation. It turned out that the actual otter inhabits. The EN-Simulator analysis can predict how spatial properties affect the likelihood of major movement paths selection, and the analytical values are used to utilize additional habitats within the major movement paths. It is judged that it can be used as basic data such as to grasp the danger area of road kill in advance and prevent it.

Compatibility of Double Cropping of Winter Wheat - Summer Grain Crops in Paddy Field of Southern Korea (남부지역 논의 밀 이모작에서 하계 곡실작물 도입의 적합성)

  • Seo, Jong-Ho;Hwang, Chung-Dong;Oh, Seong-Hwan
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.66 no.1
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    • pp.18-28
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    • 2021
  • The growth period and productivity of cropping system of winter wheat-rice, winter wheat-bean and winter wheat-grain corn for 4 years from 2015 to 2018 were compared at the experimental field of National Institute of Crop Science in Miryang city. The harvest period of winter wheat was in mid-June, and summer crops were sown (transplanted) in late June. In transplanting of rice in late June, there was no difficulty in securing the heading of panicle and the yield of rice, but there was a lot of trouble in sowing wheat in proper time because the harvest time of rice was delayed to early November due to late maturity of rice, particularly in the mid-late maturing cultivar. There was no problem in soybean planting after winter wheat because the proper period of soybean planting is late-June. In addition, there was no problem in winter wheat sowng after soybean because the maturity period of soybean was mid-October. Selection of grain maize in double cropping with winter wheat in terms of growing periods, was desirable because grain maize had the fastest maturity among summer crops. In double cropping of winter wheat-summer crops, wheats combined with soybean and grain maize showed stable yields during three years, but there was a risk of yield declines in the wheat combined with rice in heavy rainfall year. It was possible to secure high yields in three summer crops as yields of rice, soybean, and corn were 600, 350, and 800 kg/10a, respectively. Summer crops with medium maturity was recommended because of no significant difference in yield between medium maturity and medium-late maturity cultivar. Soil physical properties were improved in soils cultivated with soybean and grain maize. Therefore, It was thought that double cropping systems of winter wheat with soybean and grain maize were superior to that of winter wheat with rice in terms of connecting period between winter wheat - summer crops and improvement of soil physical properties, and total income, particularly in soybean.

Current Trends for National Bibliography through Analyzing the Status of Representative National Bibliographies (주요국 국가서지 현황조사를 통한 국가서지의 최신 경향 분석)

  • Lee, Mihwa;Lee, Ji-Won
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.32 no.1
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    • pp.35-57
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    • 2021
  • This paper is to grasp the current trends of national bibliographies through analyzing representative national bibliographies using literature review, analysis of national bibliographies' web pages and survey. First, in order to conform to the definition of a national bibliography as a record of a national publication, it attempts to include a variety of materials from print to electronic resources, but in reality it cannot contain all the materials, so there are exceptions. It is impossible to create a general selection guide for national bibliography coverage, and a plan that reflects the national characteristics and prepares a valid and comprehensive coverage based on analysis is needed. Second, cooperation with publishers and libraries is being made to efficiently generate national bibliography. For the efficiency of national bibliography generation, changes should be sought such as the standardization and consistency, the collection level metadata description for digital resources, and the creation of national bibliography using linked data. Third, national bibliography is published through the national bibliographic online search system, linked data search, MARC download using PDF, OAI-PMH, SRU, Z39.50, and mass download in RDF/XML format, and is integrated with the online public access catalog or also built separately. Above all, national bibliographies and online public access catalogs need to be built in a way of data reuse through an integrated library system. Fourth, as a differentiated function for national bibliography, various services such as user tagging and national bibliographic statistics are provided along with various browsing functions. In addition, services of analysis of national bibliographic big data, links to electronic publications, and mass download of linked data should be provided, and it is necessary to identify users' needs and provide open services that reflect them in order to develop differentiated services. Through the current trends and considerations of the national bibliographies analyzed in this study, it will be possible to explore changes in national and international national bibliography.

The Impact of Antibiotic Burden on the Selective Resistance of Gram Negative Bacteria in Children (소아청소년에서의 항생제 사용량 변화에 따른 그람음성 균주의 항생제 내성률 변화 양상)

  • Park, Sera;Lee, Euntaek;So, Hye Jin;Yoo, Ree Nar;Lee, Jina
    • Pediatric Infection and Vaccine
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    • v.28 no.2
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    • pp.82-91
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    • 2021
  • Background: The purpose of this study was to investigate the association between antibiotic use and the antimicrobial resistance of gram-negative bacteria isolated from blood cultures in a pediatric population. Methods: From January 2014 to June 2018, the antibiotic resistance pattern of Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa obtained from bacteremic patients aged ≤18 years hospitalized at Asan Medical Center Children's Hospital was analyzed and the parenteral antibiotic consumption data were retrieved. Results: During the study period, the blood culture was positive for K. pneumoniae (6.4%; 105/1,628), E. coli (5.6%; 91/1,628), P. aeruginosa (3.3%; 54/1,628), and A. baumannii (2.5%; 41/1,628), and the extended-spectrum antibiotic resistance rate of gram-negative bacteria was consistently high. The overall resistance rate of E. coli and K. pneumoniae to extendedspectrum cephalosporin was 49.3% and 54.4%, respectively. Carbapenem-resistant E. coli was first detected in 2014; its overall resistance rate to carbapenem was 5.3%. There was a linear correlation between the usage of 3rd generation cephalosporin and the resistance of A. baumannii (r2=0.96, P=0.004) and carbapenem usage and the resistance of K. pneumoniae (r2=0.79, P=0.045). Conclusions: A positive linear correlation was observed between antibiotic resistance and the corresponding antibiotic usage in 3rd generation cephalosporin resistant A. baumannii and carbapenem resistant K. pneumoniae. The judicious use of antibiotics in healthcare settings is important to minimize selection for extended-spectrum β-lactamase (ESBL) and carbapenem resistance in gram-negative bacteria.

Possibility of Using Non-selective Herbicides as Desiccants for Improving Soybean Harvest Efficiency (콩 수확 효율 증진을 위한 건조제로서 비선택성 제초제의 활용 가능성)

  • Won, Ok Jae;Hong, Seo yeon;Suh, Eun Ji;Park, Jae-Sung;Lee, Hong Seok;Park, Jin-Ki;Ryu, Jong-Soo;Han, Won-Young;Han, Kil Su;Song, Duk Young
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.66 no.4
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    • pp.358-364
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    • 2021
  • This study was conducted to select a desiccant and determine its concentration for safe usage to improve the harvesting efficiency of soybeans. Soybeans were treated with a desiccant (non-selective herbicide) before and after the maturation stage. The drying effect of the desiccant was higher at earlier treatment times than at the maturation stage, but the difference was not statistically significant. The higher efficacy might be related to the drying process of the leaves and stems, with most of the leaves and stems having already been dried by the time of hand harvesting. Desiccant treatments had no adverse effects on soybean yield, weight of 100 grains, seed quality, or seed germination rate compared with the untreated control. Pesticide residue analysis showed minimum residue concentration to be lower than the tolerance level of pesticide residues. In conclusion, it was confirmed that the desiccant was effective in drying soybean, and that there was no damage to the quality of soybean seeds. In addition to the drying effect, the dessicant treatment also facilitates the removal of weeds that interfere with the mechanical harvest and improves harvesting efficiency through the drying of the growth imbalanced individual. The desiccant treatment is expected to shorten the mechanical harvesting time by 1-2 weeks. It is thought that the selection of the proper cultivation period for other crops after soybean cultivation will be more advantageous.