• The Korean Journal of Physiology and Pharmacology
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• v.22 no.4
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• pp.427-436
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• 2018

The objective of this study was to analyze the concurrent treatment effects of ursolic acid (UA) and low-intensity treadmill exercise and to confirm the effectiveness of UA as an exercise mimetic to safely improve muscle atrophy-related diseases using Sprague-Dawley (SD) rats with skeletal muscle atrophy. Significant muscle atrophy was induced in male SD rats through hind limb immobilization using casting for 10 days. The muscle atrophy-induced SD rats were group into four: SED, sedentary; UA, daily intraperitoneal UA injection, 5 mg/kg; EX, low-intensity (10-12 m/min, $0^{\circ}$ grade) treadmill exercise; and UEX, daily intraperitoneal UA injection, 5 mg/kg, and low-intensity (10-12 m/min, $0^{\circ}$ grade) treadmill exercise. After 8 weeks of treatment, endurance capacity was analyzed using a treadmill, and tissues were extracted for analysis of visceral fat mass, body weight, muscle mass, expression of muscle atrophy- and hypertrophy-related genes, and endurance capacity. Although the effects of body weight gain control, muscle mass increase, and endurance capacity improvement were inadequate in the UA group, significant results were confirmed in the UEX group. The UEX group had significantly reduced body weight and visceral fat, significantly improved mass of tibialis anterior and gastrocnemius muscles, and significantly decreased atrophy-related gene expression of MuRF1 and atrogin-1, but did not have significant change in hypertrophy-related gene expression of Akt and mTOR. The endurance capacity was significantly improved in the EX and UEX groups. These data suggest that concurrent treatment with low-intensity exercise and UA is effective for atrophy-related physical dysfunctions.

• Toxicological Research
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• v.8 no.2
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• pp.265-272
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• 1992

Effects of repeated physical exercise on the carbon tetrachloride ($CCl_4$) hepatotoxicity were examined in adult female rats. Rats were introduced into a cylindrical rotating cage and forced to exercise for 1 hr each day, 6days/week, for 5 consecutive weeks at a speed starting from 10m/min, increased by 1m/min per day until the speed reached 27m/min. Significantly less body weight gain was observed in the exercise group suggesting that physical fitness had been induced in these animals. Eighteen hours following termination of the last exercise bout rats were treated with $CCl_4$(2 mmol/kg.ip). The $CCl_4$-induced heptotoxicity was significantly potentiated in the repeated exercise group compared to the resting sedentary animals as determined by changes in serum sorbitol dehydrogenase (SDH), glutamic oxaloacetic transaminase(GOT), glutamic pyruvic transaminase (GPT), and glucose-6-phosphatase(G-6-Pase) activities when measured 24hrs following the $CCl_4$ treatment. Hepatic drug metabolizing activity was determined in order to elucidate the underlying mechanism of potentiating action of the $CCl_4$ hepatotoxicity induced by repeated physical exercise. Repeated exercise increased the hepatic microsomal cytochrome P-450 contents and aminopyrine N-demethylase activity. The results suggest that the potentiation of $CCl_4$ hepatotoxicity by repeated exercise is associated with induction of the mixed function oxidase (MFO) enzyme system mediating the metabolism of $CCl_4$ to its active metabolite(s).

• Journal of Community Nutrition
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• v.6 no.1
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• pp.48-54
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• 2004

The purpose of this study was to examine the effects of dietary protein and exercise on bone mineral density and bone mineral content of growing male rats. Forty male, Sprague-Dawley rats(age 21 days) were assigned to four groups that underwent 9 weeks of experimental treatment. Animals were assigned to one of two exercise treatments (treadmill running or sedentary). The exercise and nonexercise group were fed a diet containing casein or soy with rich isoflavones (3.4mg/g protein). The exercise group ran on a rodent treadmill(speed of 15m/min for 30min) three days per week during the 9-week study period. All rats were fed an experimental diet and deionized water ad libitum for 9 weeks. Total bone mineral density (BMD), total bone mineral content (BMC), total body calcium, spine BMD and BMC, and femur BMD and BMC were determined by using dual energy x-ray absorptiometry (FIXI-mus, GE Lunar Radiation Cooperation, Madison, WI, USA). The soy diet group appears to have a significantly higher total BMD/weight and total BMC/ weight, spine BMD/weight, spine BMC/weight, femur BMD/weight and femur BMC/weight compared to the casein group in nonexercise and exercise. The exercise group had significantly greater total BMD/weight and BMC/ weight, spine BMD/weight and BMC/weight, femur BMD/weight and BMC/weight compared to the nonexercise group when the protein source was casein. The exercise combined soy group had significantly greater total BMD/weight and BMC/weight, spine BMD/weight and BMC/weight, femur BMD/weight and BMC/weight, compared to the exercise combined casein group. The results indicate that exercise had a positive influence on bone mineral density and bone mineral content and soy significantly affect on bone mineral density and bone mineral content for the 9 weeks experimental period. It can be concluded that exercise combined with a soy diet is most beneficial for acquisition of spine bone mineral density in young growing male rats. This convincing evidence suggests that a change in life style such as increasing exercise and consumption of soy protein is a practical strategy for significantly reducing the incidence of osteoporosis.

• Journal of the Korean Society of Clothing and Textiles
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• v.43 no.6
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• pp.866-876
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• 2019

This study examined the physiological and psychological effects of wearing gloves at rest in a cold environment. Seven elderly females participated in two separate trials: wearing gloves (WG) and bare hands (BH). The experiment was conducted for 60 min in a climatic chamber (air temperature 7.8±0.3℃ with 44±2%RH) with a sedentary posture. Microclimate temperature on the left palm was 4.16℃ higher in WG compared to that in BH (p<.1). Microclimate temperature on the chest during the last 5 min increased compared to the initial 5 min only in WG (p<.05). During the last 5 min, skin temperatures at the arm and hand in WG were higher than those in BH (p<.05). There was no statistical difference in the change of rectal temperature between WG and BH. Heart rate in BH was significantly higher compared to the WG (p<.05). Subjects also felt less cold on the whole body and hand in WG than those in BH (p<.05). The findings indicate that wearing gloves for elderly females affected the distribution of skin temperature and cardiovascular response in cold environments. Elderly females should be informed about the importance of wearing gloves through the clothing guideline in winter.

• The Korean Journal of Zoology
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• v.33 no.3
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• pp.297-302
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• 1990

The effects of ginseng saponin on the activity of serum alanine aminoiransferase (ALT) in trained rats were examined. The trained group was given a chronic swimming bout (approx. 90 min/day) for 50 days, and ginseng group was given an oral administration of ginseng saponin (150mg/kg/day) for 2 weeks. Ginseng treated-trained group was given an oral administration of ginseng saponin for 2 weeks prior to the termination of a swimming bout. In this experiment, male rats of Sprague-Dawley strain (250 $\pm$ 20 g) were used. The activities of serum ALT in trained and in ginseng groups increased 72.89% (P < 0.01) and 57.14% (P < 0.01) than in control groups, respectively. Also, the activities of serum ALT increased 69.66% (P <0.01) in saline treated-trained group, and 79.31% (P < 0.01) in ginseng treated-trained group than in control groups which were given saline solution and kept sedentary. The effect of ginseng saponin, as revealed by comparing the ginseng treated-trained group with the saline treated-trained group, was not significant. The present study suggests that training and ginseng saponin significantly increased the activity of serum ALT in rats, but that, in ginseng treated-trained group, ginseng saponin did not raise any further the increased activity of serum ALT by training.

• Journal of Korean Academy of Nursing
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• v.46 no.1
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• pp.140-148
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• 2016

Purpose: This study was performed to determine the physical and psychological effects of an urban forest-walking program for office workers. For many workers, sedentary lifestyles can lead to low levels of physical activity causing various health problems despite an increased interest in health promotion. Methods: Fifty four office workers participated in this study. They were assigned to two groups (experimental group and control group) in random order and the experimental group performed 5 weeks of walking exercise based on Information-Motivation-Behavioral skills Model. The data were collected from October to November 2014. SPSS 21.0 was used for the statistical analysis. Results: The results showed that the urban forest walking program had positive effects on the physical activity level (U=65.00, p <.001), health promotion behavior (t= - 2.20, p =.033), and quality of life (t= - 2.42, p =.020). However, there were no statistical differences in depression, waist size, body mass index, blood pressure, or bone density between the groups. Conclusion: The current findings of the study suggest the forest-walking program may have positive effects on improving physical activity, health promotion behavior, and quality of life. The program can be used as an effective and efficient strategy for physical and psychological health promotion for office workers.

• Journal of the Korean housing association
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• v.20 no.6
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• pp.19-29
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• 2009

The purpose of this study is to clarify the spatial changes that have taken place in the main rooms (Anbang) and kitchens of traditional Utbangkkeokeum houses in Cheongju city, located on the central inland of Korea. These houses consist of a main house (Momchae) and a single-wing house (Nalgaechae), creating an ㄱ-shaped plan. The kitchen is in the front of the Nalgaechae, and the Anbang is at the rear. For the Momchae, the main hall (Daechung) is next to the Anbang, which is at the end of the Nalgaechae, and the room (Gunnunbang) is situated across from the Daechung. This study is based on the assumption that these houses have been conserved and altered from their original forms. As a result of alterations, many changes have occurred to the main room and kitchen spaces. The traditional main room is connected with two rooms (Utbang and Araebang), new standup kitchens are introduced, and floor heating systems are installed. The Anbang has maintained its sedentary lifestyle and the space for major daily activities such as sleeping and TV viewing. Also, TV viewing is a distinctive feature for residential purposes and the bedding is located in such a position that it is easy to observe any exterior movement for the elderly living alone. The layout of the standup kitchen has been altered to maintain the previous circulation, position and function of the entrance. Also, the kitchen and dining room were used together, and the size of these rooms has been partially increased from the original module in different ways for each case. The above findings suggest that Utbangkkeokeum houses of Cheongju city have been spatially changed while maintaining the previous lifestyle.

• Journal of the Korean Institute of Rural Architecture
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• v.18 no.2
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• pp.29-37
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• 2016

This study is aimed to suggesting a hypothesis about the process of improvement of houses of the Korean-Chinese, comparing how Han Chinese and Korean-Chinese houses changed in Yanbian Area of China. This draws the conclusion by analyzing the field survey about residence of the Han Chinese and the Korean-Chinese in Yanbian Area of China. First of all, the characteristic of residence style change and the plan of rural houses of the Han Chinese are in the following. The plan of houses has been changed from allocating rooms from side to side with the kitchen as the center to linking each functional spaces through the aisle. And the main bedroom of houses becomes the central space for family members instead of Kang (partial Ondol) by expanding the floor heating system under the whole floor in houses. Next, the feature of residence style changes of the Han Chinese and the Korean-Chinese is as follows. In 1970s barns disappeared from houses of the Korean Chinese, but houses of the Han Chinese were not much changed. From 1980s to 1990s, spaces linking each rooms with aisles had appeared for comfortableness of residence and respecting each individual's privacy. On the other hand, The houses of the Korean-Chinese make a whole big space by getting rid of walls between the rooms. And after 2 thousand years later, Han Chinese houses have a bedroom with floor heating system. Both houses of the Korean-Chinese and the Han Chinese are changed to have a residence style which taking sedentary style and standing style.

• Korean Journal of Environment and Ecology
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• v.29 no.2
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• pp.192-199
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• 2015

This study was conducted to investigate the movement and home range of the red-tongued viper snake (Gloydius ussuriensis) from June 2006 to June 2009. This snake species inhabits an islet on Jeju Island, Gapado. A total of 132 individual snakes were marked during the study. Among the marked individuals, the number of snakes recaptured more than once was 22 (16.8 %) and the number of individuals recaptured more than twice was eight (6.1 %), indicating a relatively low recapture rate. The durations from capture to recapture varied from 1 to 710 days. However, the capture points were not much different, indicating that the moved distance of snakes and the interval between capture-recapture were not correlated. The home ranges of the Red-tongued viper snakes calculated from data of the snakes which were captured more than three times using the MCP(minimum convex polygon) method were $8{\sim}167m^2(64.0{\pm}57.0m^2)$, suggesting that this snake is relatively sedentary. Home range size differences between female ($Mean=62.0m^2$) and male ($Mean=66.0m^2$) snakes were not significant. In the red-tongued viper population of Gapado, there was no statistically significant relationship between body size and home range size although it was positively correlated (r=0.675). Our results provide valuable data to understand life patterns of the red-tongued viper snakes and will be useful when conducting further ecological studies on other snake species.

• Child Health Nursing Research
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• v.6 no.1
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• pp.18-31
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• 2000

Recently, the number of obese people have been increasing due to westernized diets and increased sedentary activity. In particular, obese adolescent have been newly recognized as having significant health problems. This study focuses on determining the gender difference of obese adolescents through implementation of a structured questionnaire on general characteristics, attitudes toward dieting, eating habits and emotional depression due to obesity. Data collection was carried out by 291 students in attendance at 3 high schools in Pusan from 11. 2. 1998 to 11. 30. 1998. The targets were 148 boys and 143 girls who were judged as obese in the school's physical check-up. The test of reliability of this research was calculated by chronbach's α. Data analysis was managed by computer and statistics by SPSS/WIN. The results of the survey are as follows: 1. For the questionnaire regarding attitudes toward dieting which include 28 items, 10 out of 28 items (about 36%)showed gender difference. 2. For the questionnaire regarding eating habits which include 17 items, 5 out of 17 items (about 30%)showed gender difference. 3.For the questionnaire regarding emotional depression about obesity, 30.6% of boys and 27.3% girls answered but no statistical significance. The results of this survey indicated that this study will be important as a good guideline for treating obese adolescents. It is hoped that much more research on gender difference in obese adolescents will be implemented in the future. In addition, the development of effective treatments for obesity should be based on the gender of the adolescent.