• Interdisciplinary Bio Central
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• 제1권2호
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• pp.8.1-8.6
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• 2009

Introduction: It is a challenge to design a protein score function which stabilizes the native structures of many proteins simultaneously. The coarse-grained description of proteins to construct the pairwise-contact score function usually ignores the backbone directionality of protein structures. We propose a new two-body score function which stabilizes all native states of 1,006 proteins simultaneously. This two-body score function differs from the usual pairwise-contact functions in that it considers two adjacent amino acids at two ends of each peptide bond with the backbone directionality from the N-terminal to the C-terminal. The score is a corresponding propensity for a directional alignment of two adjacent amino acids with their local environments. Results and Discussion: We show that the construction of a directional adjacency-score function was achieved using 1,006 training proteins with the sequence homology less than 30%, which include all representatives of different protein classes. After parameterizing the local environments of amino acids into 9 categories depending on three secondary structures and three kinds of hydrophobicity of amino acids, the 32,400 adjacency-scores of amino acids could be determined by the perceptron learning and the protein threading. These could stabilize simultaneously all native folds of 1,006 training proteins. When these parameters are tested on the new distinct 382 proteins with the sequence homology less than 90%, 371 (97.1%) proteins could recognize their native folds. We also showed using these parameters that the retro sequence of the SH3 domain, the B domain of Staphylococcal protein A, and the B1 domain of Streptococcal protein G could not be stabilized to fold, which agrees with the experimental evidence.

• Bulletin of the Korean Chemical Society
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• 제30권11호
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• pp.2589-2594
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• 2009

Aging phenomena of plasma polymer films were studied by using the surface analysis techniques of contact angle measurement, X-ray photoelectron spectroscopy (XPS), time-of-flight secondary ion mass spectrometry (TOFSIMS), and atomic force microscopy (AFM). The polymer films were grown on an aluminum substrate by using a plasma polymerization method from a gas mixture of acetylene and helium, and the films were subsequently modified to have a hydrophilic surface by oxygen plasma treatment. Aging of the polymer films was examined by exposing the samples to water and air environments. The aging process increased the hydrophobicity of the surface, as revealed by an increase in the advancing contact angle of water. XPS analysis showed that the population of oxygen-containing polar groups increased due to the uptake of oxygen during the aging, whereas TOF-SIMS analysis revealed a decrease in the polar group population in the uppermost surface layer. The results suggest that the change in surface property from hydrophilic to hydrophobic nature results from the restructuring of polymer chains near the surface, rather than compositional change of the surface. Oxidative degradation may enhance the mobility and the restructuring process of polymer chains.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2007년도 하계학술대회 논문집 Vol.8
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• pp.111-111
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• 2007

Further scaling the semiconductor devices down to low dozens of nanometer needs the extremely shallow depth in junction and the intentional counter-doping in the silicon gate. Conventional ion beam ion implantation has some disadvantages and limitations for the future applications. In order to solve them, therefore, plasma source ion implantation technique has been considered as a promising new method for the high throughputs at low energy and the fabrication of the ultra-shallow junctions. In this paper, we study about the effects of DC bias and base pressure as a process parameter. The diluted mixture gas (5% $PH_3/H_2$) was used as a precursor source and chamber is used for vacuum pressure conditions. After ion doping into the Si wafer(100), the samples were annealed via rapid thermal annealing, of which annealed temperature ranges above the $950^{\circ}C$. The junction depth, calculated at dose level of $1{\times}10^{18}/cm^3$, was measured by secondary ion mass spectroscopy(SIMS) and sheet resistance by contact and non-contact mode. Surface morphology of samples was analyzed by scanning electron microscopy. As a result, we could accomplish the process conditions better than in advance.

• 한국안전학회지
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• 제34권3호
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• pp.83-88
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• 2019

The 7,993 cases of Survey Report of Fatal Industrial Accidents conducted jointly by the MEOL and the KOSHA for the recent seven years(2007-2013) were categorized according to personal and occupational characteristics, industry types, business sizes, job types, activities at the time accident, types of accidents, material agents(assailing materials), unsafe conditions, and unsafe acts. And it is found that among the 72.2 percent of fatal occupational accidents in the construction and manufacturing industries are caused by falling, sticking, bumping and being caught under objects & overturning. For this study, through the empirical analysis on causes of fatal industrial accidents, was used to identity high risk groups based on total data of 7,993 victims of occupational accidents. An annual fatal occupational injury (FOI) rate per 10,000 workers was about 0.47‱. The middle-aged group and the elderly group showed the highest FOI rates per 10,000 workers (0.73‱, 0.80‱), and the daily workers showed the highest FOI rate (1.46‱), and the craft and related trades workers showed the highest FOI rate (2.17‱). In case of industry type the mining industry (7.26‱) showed the highest FOI rate, followed by the sewerage, waste management, materials recovery and remediation activity industry (3.91‱) and the construction industry (2.71‱). The primary high risk target group that requires a strategy designed to reduce fatal occupation injuries caused by falling and bumping & contact(collision) is the construction industry, and the secondary high risk target group in the construction industry is classified as the equipment, machine operating and assembling workers in the construction industry, those aged 50 years old and above need the prevention measures against bumping & contact(collision) and being caught under an object & falling(objects), while those aged less than 50 years old need prevention measures against falling(persons).

• 근관절건강학회지
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• 제28권2호
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• pp.174-182
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• 2021

Purpose: This study is a secondary data analysis study to identify factors related to the quality of life of people aged 65 y or older, according household type. Methods: In 2019, the study extracted the data from the elderly participants (65 y of age or older) from G province Community Health Survey. The data were compiled and analyzed in a composite sample. Results: The quality of life was lowest among single people, grandparents-grandchildren (F=39.88, p<.001). Variables that significantly influenced quality of life in single-person households were basic security(β=-.03, p=.002), high-risk drinking (β=.04, p=.002), number of day to walk (β=.01, p<.001), diabetes mellitus (β=-.03, p<.001), depression (β=-.02, p<.001), and contact frequency (β=.00, p<.001). Variables that significantly influenced grandparents-grandchildren households were basic security (β=.03, p<.001), smoking(β=-.02, p<.001), number of day to walk (β=.00, p<.001), hypertension (β=-.01, p=.009), diabetes mellitus (β=-.04, p<.001), cognitive impairment (β=-.02, p<.001), depression(β=-.02, p<.001), contact frequency (β=.01, p<.001), and neighborhood trust (β=.02, p<.001). Conclusion: In this study, there were differences in health-related quality of life for each type of household, and various support systems are needed in their social networks to suit their characteristics.

• 전기화학회지
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• 제17권1호
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• pp.7-12
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• 2014

리튬이차전지의 고에너지 밀도화를 위해 전지 구성요소들의 무게 및 부피를 저감하려는 요구가 증가하고 있다. 분리막은 리튬이온의 이동통로를 제공할 뿐만 아니라 양극과 음극의 직접적인 접촉을 방지하는 핵심 부품이다. 본 연구에서는 연신 비율을 달리하여 습식방법을 통해 두께가 16, 12, $9{\mu}m$ 인 폴리에틸렌 분리막을 준비하였고, 각각의 기계적 강도 및 열적특성을 평가하였다. 또한 양극($LiCoO_2$), 음극(Graphite)을 사용한 Coin type full-cell을 제작하여 율속 특성 및 500cycle까지 사이클 수명특성을 평가하였다. 수명특성 평가를 통해 사용된 모든 두께의 분리막에서 500cycle 까지 큰 차이 없이 80% 정도의 용량유지 결과를 확인하였다. 율속 특성에서는 가장 얇은 $9{\mu}m$ 분리막이 가장 우수한 성능을 나타내었다. 흥미롭게도 $9{\mu}m$의 분리막이 $16{\mu}m$ 경우보다 열 수축률 평가에서 우수한 특성을 나타내었다.

• 한국환경농학회지
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• 제22권2호
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• pp.111-117
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• 2003

모래층 토양이 도시하수의 3차 처리에 이용될 경우 COD 제거율은 적용유량에 관계없이 약 70%에 이르는 것을 알 수 있었다. 적용유량이 증가함에 따라 COD제거에 필요한 토양 층의 깊이가 증가하여 50 L/day의 유량에서는 약 60 cm에 달하는 것을 알 수 있었다. 질산화는 매우 빨라서 표층토양 $10{\sim}20\;cm$에서 반응이 거의 완료됨을 알 수 있었다. 총 질소의 제거율은 유량에 상관없이 약 20%로 낮은 편이었으며, 이에 대한 보완책이나 추가적인 연구가 필요한 것으로 판단된다. 잔디를 식재할 경우 오염물의 처리효율에는 영향이 거의 없으나 투수능 유지에는 도움이 되는 것을 알 수 있었으며, 토양에 함유된 유기물로부터 상당한 양의 오염물이 용출되는 것을 알 수 있었다. 탈질과정에서는 아산화질소도 발생하므로 본 연구의 결과를 현장에 적용하기 전에 이에 대한 추가적인 연구도 필요할 것으로 판단된다.

• Journal of Astronomy and Space Sciences
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• 제12권1호
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• pp.21-29
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• 1995

$\beta$ Lyrae형 식쌍성 AW Cam을 UBV 세파장 영역에서 광전 관측하여 얻은 UBV 광도곡선을 Wilson and Devinney 쌍성 모델의 2가지 mode( mode 2와 mode 5)로 분석하였다. 이는 Russo and Milano (1983)가 산출한 측광 질량비(q=0.21)와 Mammano et al. (1967)의 분광질량비(q=0.43)가 일치하지 않는 모순-AW Cam 계의 남아 있는 문제인-올 해결하기 위한 것이다. Mode 2로 구한 측광학적 해가 mode 5로 구한 해보다 관측된 광도곡선을 더 잘 반영하는 것으로 계산되었다. 이는AW Cam이 정상준분리형계가 아나라 분리형 쌍성계임을 제시하는 것으로 해석될 수 있다. 또한 산출한 질량비 (q=0.43)로 계산한 AW Cam계의 삼차원 로쉬 모형을 보면 가벼운 반성은 안쪽 로쉬 한계면에 잘 들어 있는 반연 더 무거운 주성이 로쉬 한계면에 거의 접촉하고 있다. 로쉬 기하, 공전주기의 일정성, 그리고 다른 측광학적 증거들로 부터 AW Cam은 Giuricin and Mardrossian (1981)이 제안한 ‘접촉이 깨진 상태’에 있는 진화된 분리형 쌍성계가 아니라, ‘접촉 상태’로 가고 있는case A 진화 상 태에 있는 덜 진화된 분리형 쌍성계로 잠정적으로 결론짓는다

• Journal of Astronomy and Space Sciences
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• 제33권3호
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• pp.185-196
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• 2016

New multiband BVRI light curves of NSVS 1461538 were obtained as a byproduct during the photometric observations of our program star PV Cas for three years from 2011 to 2013. The light curves indicate characteristics of a typical W-subtype W UMa eclipsing system, displaying a flat bottom at primary eclipse and the O'Connell effect, rather than those of an Algol/b Lyrae eclipsing variable classified by the northern sky variability survey (NSVS). A total of 35 times of minimum lights were determined from our observations (20 timings) and the SuperWASP measurements (15 ones). A period study with all the timings shows that the orbital period may vary in a sinusoidal manner with a period of about 5.6 yr and a small semi-amplitude of about 0.008 day. The cyclical period variation can be interpreted as a light-time effect due to a tertiary body with a minimum mass of 0.71 M_⊙. Simultaneous analysis of the multiband light curves using the 2003 version of the Wilson-Devinney binary model shows that NSVS 1461538 is a genuine W-subtype W UMa contact binary with the hotter primary component being less massive and the system shows a low mass ratio of q(m_c/m_h)=3.51, a high orbital inclination of 88.7°, a moderate fill-out factor of 30 %, and a temperature difference of ΔT=412 K. The O'Connell effect can be similarly explained by cool spots on either the hotter primary star or the cool secondary star. A small third-light corresponding to about 5 % and 2 % of the total systemic light in the B and V bandpasses, respectively, supports the third-body hypothesis proposed by the period study. Preliminary absolute dimensions of the system were derived and used to look into its evolutionary status with other W UMa binaries in the mass-radius and mass-luminosity diagrams. A possible evolution scenario of the system was also discussed in the context of the mass vs mass ratio diagram.

• 공업화학
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• 제17권3호
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• pp.321-326
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• 2006

폐발포폴리스티렌(WEPS)의 열분해 반응시 부생되는 약 5~15%의 난분해성 스티렌 이량체 유분(SDF, 주성분: 47 wt% 1,3-diphenylpropane)의 열분해방법에 대하여 검토하였다. 가압열분해반응에서는 반응온도 $360^{\circ}C$에서 152~202 kPa이 최적의 조건으로 판단되었다. 이 반응조건에서 오일 수율 73.8%와 벤젠 0.4%, 톨루엔 30.9%, 에틸벤젠 15.0%, 스티렌 19.6%, 알파메틸스티렌 4.2%의 선택율로 얻을 수 있었다. 상압연속 열분해반응에서는 반응온도 $510{\sim}610^{\circ}C$, 접촉시간 2~24 min의 무촉매 반응에 대하여서는 온도와 접촉시간이 증가할수록 상기 생성물의 수율이 증가하였고 촉매 반응에 대하여서는 산촉매, 염기성촉매 및 산화환원촉매의 활성에 대하여 검토한 결과 $Cr_2O_3$ 촉매가 가장 높은 활성을 보여주었다. $Cr_2O_3$ 촉매를 사용하여 $560^{\circ}C$, 접촉시간 24 min의 조건에서 전환율 74.6%와 벤젠 0.4%, 톨루엔 21.6%, 에틸벤젠 9.7%, 스티렌 17.9%, 알파메틸스티렌 3.5%의 수율을 각각 얻을 수 있었다. 이때의 반응 메커니즘은 스티렌이 열에 의해 diradical을 경유하여 에틸벤젠이나 다른 부생성물을 생성시키는 것으로 추측된다.