• 한국환경과학회지
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• 제28권4호
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• pp.441-454
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• 2019

The present study analyzes the characteristics of 43 typhoons that affected the Korean Peninsula between 2002 and 2015. The analysis was based on 3-second gust measurements, which is the maximum wind speed relevant for typhoon disaster prevention, using a typhoon disaster prevention model. And the distribution and characteristics of the 3-second gusts of four typhoons, RUSA, MAEMI, KOMPASU, and BOLAVEN that caused great damage, were also analyzed. The analysis show that between May and October during which typhoons affected the Korean Peninsula, the month with the highest frequency was August(13 times), followed by July and September with 12 occurrences each. Furthermore, the 3-second gust was strongest at 21.2 m/s in September, followed by 19.6 m/s in August. These results show that the Korean Peninsula was most frequently affected by typhoons in August and September, and the 3-second gusts were also the strongest during these two months. Typhoons MAEMI and KOMPASU showed distribution of strong 3-second gusts in the right area of the typhoon path, whereas typhoons RUSA and BOLAVEN showed strong 3-second gusts over the entire Korean Peninsula. Moreover, 3-second gusts amount of the ratio of 0.7 % in case of RUSA, 0.8 % at MAEMI, 3.3 % at KOMPASU, and 21.8 % at BOLAVEN showed as "very strong", based on the typhoon intensity classification criteria of the Korea Meteorological Administration. Based on the results of this study, a database was built with the frequencies of the monthly typhoons and 3-second gust data for all typhoons that affected the Korean Peninsula, which could be used as the basic data for developing a typhoon disaster prevention system.

• 한국응급구조학회지
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• 제10권2호
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• pp.5-14
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• 2006

The purpose of this study was supply basic information and positive attitude needed to understand the disabled person through the analysing EMT Dept. student reaction on the disabled person. The subjects for this study were 251 students from G-college in In-Cheon City. The subjects were separated as the EMT dept. students and general dept student. The instrument used for this study were Lazer. Bonett and Granaff(1973). The scale of attitude on the disabled person. Data were analyzed by use of two-sample t-test and correlation coefficient with SAS program. Results are as follows ; 1. Frist, the EMT Dept. students showed more positive and optimistic attitude on the disabled person as safety prevention with their family life and safety prevention with first impression, but the general dept. student showed more positive and optimistic attitude on the disabled person as safety prevention with their self-consciousness, safety prevention with operative capacity, safety prevention with social life and safety prevention with school life. 2. Second, on attitude of 1 or 2 grade, first grade showed more positive and optimistic attitude on the disabled person as safety prevention with self-consciousness and safety prevention with operative capacity. Second grade showed more positive and optimistic attitude on the disabled person as safety prevention with social life, safety prevention with family life and safety prevention with school life. and first impression. But disabled person as safety prevention with self-consciousness, safety prevention with operative capacity, safety prevention with social life, safety prevention with school life and first impression. 3. Third, in interrelation effect analysing each section department and grade. They showed and interrelated more positive and optimistic attitude on the disabled person as safety prevention with their social life and first impression. As a results, it is important to understand disabled person whose physical condition. Especially, this study suggests to need to endeavor safety prevention for disabled person.

• 한국인터넷방송통신학회논문지
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• 제13권6호
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• pp.131-136
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• 2013

해마다 아동, 치매노인, 장애인과 같은 사회약자의 실종 발생률이 증가하고 있다고 한다. 본 논문에서는 사회약자의 실로방지, 더 나아가 실종을 방지 하고자 "블루투스 및 NFC 기반 사회약자 사고방지 시스템"을 제안하였다. 요즘 대부분의 사람들이 스마트폰을 사용한다. 이라한 스마트폰은 블루투스와 NFC 모듈을 대부분 탑재하고 있다. 본 논문에서는 이런 모듈을 탑재한 스마트폰을 이용하여 사회약자와 보호자를 위한 응용시스템인 사회약자 사고방지 시스템을 설계하고 구현하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권11호
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• pp.4489-4492
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• 2015

The precaution and treatment for cancer become inevitable with the rising of morbidity and mortality. In this article, a promising new methodology for cancer treatment, sono-dynamic therapy (SDT) was introduced. In addition, we extensively reviewed the molec-ular mechanisms of SDT killing cancer and summarized the classification of sonosensi-tizers. At the same time, research progress of SDT indicates that it is possible to become a developing field for cancer treatment in clinical application.

• Asian Pacific Journal of Cancer Prevention
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• 제14권8호
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• pp.4775-4778
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• 2013

The key signaling networks regulating cancer cell proliferation remain to be defined. The leucine-rich repeat containing G-protein coupled receptor 48 (GPR48) plays an important role in multiple organ development. In the present study, we investigated whether GPR48 functions in cancer cells using MCF-7, HepG2, NCI-N87 and PC-3 cells. We found that GPR48 overexpression promotes while its knockdown using small interfering RNA oligos inhibits cell proliferation. In addition, Wnt/${\beta}$-catenin signaling was activated in cells overexpressing GPR48. Therefore, our results indicated that GPR48 activates Wnt/${\beta}$-catenin signaling to regulate cancer cell proliferation.

• 한국정보기술학회 영문논문지
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• 제8권2호
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• pp.69-77
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• 2018

The study, recognizing the seriousness of such second-convictions of sexual violence offenders and supplementing the problems noticed from an integral electronic monitoring anklet, which only offers simple location information, would like to propose a Prevention System against Second-Convictions of Sexual Violence Offenders by using Smart Electronic Monitoring Anklet. Proposed System is anticipated to be able to prevent second-convictions of sexual violence offenders as the data of offenders from Smart Electronic Monitoring Anklet with various sensors and the data from Integrated DB of Judicial Authorities is comparatively analyzed, allowing anticipative actions at each stage based on the analyzed data regarding sexual violence.

• Asian Pacific Journal of Cancer Prevention
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• 제13권1호
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• pp.135-138
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• 2012

Objective: To investigate whether apoptin is a apoptosis-inducing protein with a potential for bladder cancer therapy. Methods: We constructed a PCDNA3/Apoptin eukaryotic expression vector, and transfected this vector into bladder cancer cell lines BIU-87 and EJ, then observed the results by RT-PCR, transmission electron microscopy, MTT assay and the flow cytometry (TUNEL method). Results: PCDNA3/Apoptin successfully induced a high level apoptosis in both bladder cancer cell lines, compared with the controls (p<0.05). Conclusions: Apoptin can induce high level apoptosis in human bladder cancer EJ and BIU-87 cells, which suggests a potential for human bladder cancer therapy.

• Asian Pacific Journal of Cancer Prevention
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• 제16권5호
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• pp.1993-1995
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• 2015

Purpose: This analysis was conducted to evaluate the efficacy and safety of irinotecan based regimens as second-line chemotherapy in treating patients with small cell lung cancer. Methods: Clinical studies evaluating the efficacy and safety of irinotecan based regimens as second-line chemotherapy for patients with small cell lung cancer were identified using a predefined search strategy. Pooled response rates (RRs) of treatment were calculated. Results: In irinotecan based regimens as second-line chemotherapy, 4 clinical studies which including 155 patients with small cell lung cancer were considered eligible for inclusion. In all chemotherapy consisted of irinotecan with or without nedaplatin. Pooled analysis suggested that, in all patients, the pooled RR was 27.1% (42/155) in irinotecan based regimens. Nausea, vomiting, diarrhea and myelosuppression were the main side effects. No grade III or IV renal or liver toxicity was observed. No treatment related death occurred with the irinotecan based treatments. Conclusion: This systemic analysis suggests that irinotecan based regimens as second-line chemotherapy are associated with mild response rate and acceptable toxicity for patients with small cell lung cancer.

• Asian Pacific Journal of Cancer Prevention
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• 제17권2호
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• pp.667-671
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• 2016

Oridonin, an ent-kaurane diterpenoid compound isolated from the traditional Chinese herb Rabdosia rubescens, has shown various pharmacological and physiological effects such as anti-tumor, anti-bacterial, and anti-inflammatory properties. However, the effect of oridonin on human ovarian cancer cell lines has not been determined. In this study, we demonstrated that oridonin inhibited ovarian cancer cell proliferation, migration and invasion in a dose-dependent manner. Furthermore, we showed oridonin inhibited tumor growth of ovarian cancer cells (SKOV3) in vivo. We then assessed mechanisms and found that oridonin specifically abrogated the phosphorylation/activation of mTOR signaling. In summary, our results indicate that oridonin is a potential inhibitor of ovarian cancer by blocking the mTOR signaling pathway.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6087-6091
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• 2012

Context: Patients diagnosed with a cancer have a life time risk of developing another de novo malignancy depending on various inherited, environmental and iatrogenic risk factors. Of late the detection of new primary has increased mainly due to refinement in both diagnostic and treatment modalities. Cancer victims are surviving longer and thus are more likely to develop a new metachronous malignancy. Aims: To report our observed trend of increase in prevalence of both synchronous and metachronous second malignant neoplasms among cancer victims and to review the relevant literature. Settings and Design: A hospital based retrospective collection of prospective data of patients diagnosed with second denovo malignancy. Materials and Method: The study was conducted over a 5 year period from July 2008 to June 2012. All patients diagnosed with a histologically proven second malignancy as per Warren Gate's criteria were included. Various details regarding sex, age at presentation, synchronous or metachronous, treatment and outcome were recorded. Conclusions: The occurrence of multiple primary malignancies is not rare. Awareness of the possibility alerts the clinician in evaluation of patients with a known malignancy presenting with unusual sites of metastasis. Individualizing the treatment according to the stages of the primaries will result in durable cancer control particularly in synchronous double malignancy.