• Journal of the Korean Data and Information Science Society
• /
• 제15권4호
• /
• pp.981-992
• /
• 2004

In this paper, we develop the noninformative priors for the common scale parameter in the inverse gaussian distributions. We developed the first and second order matching priors. Next we revealed that the second order matching prior satisfies a HPD matching criterion. Also we showed that the second order matching prior matches alternative coverage probabilities up to the second order. It turns out that the one-at-a-time reference prior satisfies a second order matching criterion. Some simulation study is performed.

• 한국산학기술학회:학술대회논문집
• /
• 한국산학기술학회 2009년도 춘계학술발표논문집
• /
• pp.280-283
• /
• 2009

Web 2.0 is changing the paradigm of using the Internet which is affecting the e-learning paradigm. E-learning 2.0 based on the Web 2.0 has a bottom-up approach which learners work on content with social networking and collaboration in their own cyberspace. Second Life is presented as a new e-learning environment. - Flexibility, - Strong social networking, - Residents’ creative activities of Second Life ⇨ Unlimited potential to educators Second Life is a classroom built in 3D cyber space.

• 충청수학회지
• /
• 제21권2호
• /
• pp.209-221
• /
• 2008

In the present paper, first we define a Douglas space of the second kind of a Finsler space with an (${\alpha},{\beta}$)-metric. Next we find the conditions that the Finsler space with an (${\alpha},{\beta}$)-metric be a Douglas space of the second kind and the Finsler space with a Matsumoto metric be a Douglas space of the second kind.

• Journal of applied mathematics & informatics
• /
• 제11권1_2호
• /
• pp.201-213
• /
• 2003

In this paper we present a second order PVT (parallel variable transformation) algorithm converging to second order stationary points for minimizing smooth functions, based on the first order PVT algorithm due to Fukushima (1998). The corresponding stopping criterion, descent condition and descent step for the second order PVT algorithm are given.

• 한국해양공학회지
• /
• 제15권1호
• /
• pp.12-18
• /
• 2001

This study concentrates on the second-order diffraction problem around circular cylinders in multi-frequency waves. The method of solution is a time-domain Rankine panel method which adopts a higher-order approximation for the velocity potential and wave elevation. In the present study, the multiple second-order quadratic transfer functions are extracted from the second-order time signal generated in random waves, and the comparison with other bench-mark test results shows a good agreement. This approach is directly applicable to prediction of nonlinear forces on offshore structures in random ocean.

• Journal of the Korean Society for Industrial and Applied Mathematics
• /
• 제23권3호
• /
• pp.179-202
• /
• 2019

This paper presents second derivative generalized extended backward differentiation formulas (SDGEBDFs) based on the second derivative linear multi-step formulas of Cash [1]. This class of second derivative linear multistep formulas is implemented as boundary value methods on stiff problems. The order, error constant and the linear stability properties of the new methods are discussed.

• BMB Reports
• /
• 제42권10호
• /
• pp.636-641
• /
• 2009

The penetrating of monoclonal antibodies (mAbs) into solid tumor may be hampered by their large size. The antibody mimetics, composed of two complementarity-determining regions (CDRs) through a cognate framework region (FR), have been demonstrated to have the capacity to penetrate tumors superior to its parental intact IgG. In this study, we used CDR and FR sequences from the humanized anti-HER2 monoclonal antibody trastuzumab to design four antibody mimetics. Then these antibody mimetics were fused to human IgG Fc to generate mimetics-Fc small antibodies. One of the four mimetics-Fc antibodies binds well to HER2-overexpressing SK-BR3 cells and effectively inhibits the binding of trastuzumab. This mimetics-Fc, denoted as HMTI-Fc, was shown to be effective in mediating antibody-dependent cellular cytotoxicity and exhibit an antiproliferative effect in SK-BR3 cells. To our knowledge, the HMTI-Fc antibody shown here is the smallest fully functional antibody and may have a potential for treatment of cancer.

• 대한치과보철학회지
• /
• 제25권1호
• /
• pp.55-69
• /
• 1987

The purpose of this study was to evaluate the stress distributions of the fixed partial denture with five unit intermediate abutment. This fixed partial denture was attached to a three dimensional photoelastic epoxy resin model. Three dimensional photoelastic models were used, with the stress areas recorded photographically. A vertical load was applied to the second molar, which is the most posterior abutment of the fixed partial denture. Similarly, a vertical load was applied to the first molar because this tooth receives the heaviest masticatory load. These loads were added to two types of fixed partial denture. the rigid connector, and the nonrigid connector which was connected on the distal side of the intermediate abutment by a key and keyway device. After the stress patterns in surrounding tissues were observed, the following conclusions were as follows: 1. When the vertical load was applied to the first and second molars on the occlusal surfaces, the surrounding tissues of the roots of the canine, the second premolar, and the second molar were all compressive stresses. 2. When the vertical load was applied on the occlusal surface of the second molar, the tissue surrounding the roots of the canine, the second premolar, and the second molar all showed more stresses with the nonrigid connector than with the rigid connector. 3. When the vertical load was applied to the occlusal surface of the first molar, the stress concentration on the canine and the second molar was similar, whether the rigid or nonrigic connectors were used. However, on the second premolar, the stress concentration shown by the nonrigid connector was noticeably more than that shown by the rigid connector. 4. Whether the rigid or nonrigid connectors were used, when the load was placed on the first molar, the stress concentration on the canine and the second premolar was greater than that observed for the second molar. When the load was placed on the second molar, the load affected the second molar more than the canine and the second premolar.

• Journal of Mechanical Science and Technology
• /
• 제14권1호
• /
• pp.84-92
• /
• 2000

A new bounce back boundary method of the second order in error is proposed for the lattice Boltzmann fluid simulation. This new method can be used for the arbitrarily irregular lattice geometry of a non-slip boundary. The traditional bounce back boundary condition for the lattice Boltzmann simulation is of the first order in error. Since the lattice Boltzmann method is the second order scheme by itself, a boundary technique of the second order has been desired to replace the first order bounce back method. This study shows that, contrary to the common belief that the bounce back boundary condition is unilaterally of the first order, the second order bounce back boundary condition can be realized. This study also shows that there exists a generalized bounce back technique that can be characterized by a single interpolation parameter. The second order bounce back method can be obtained by proper selection of this parameter in accordance with the detailed lattice geometry of the boundary. For an illustrative purpose, the transient Couette and the plane Poiseuille flows are solved by the lattice Boltzmann simulation with various boundary conditions. The results show that the generalized bounce back method yields the second order behavior in the error of the solution, provided that the interpolation parameter is properly selected. Coupled with its intuitive nature and the ease of implementation, the bounce back method can be as good as any second order boundary method.

• 대한치과교정학회지
• /
• 제20권1호
• /
• pp.123-133
• /
• 1990

The work was undertaken to evaluate the calcification of the second and the third molars in skeletal Class II and III malocclusions. The differences in the calcification stages between skeletal Class II and III malocclusion were evaluated and statistically analysed from panoramic radiographs of 202 males and females ranging in age from 11 to 15 years old. The results were as follows, 1. The calcification stages of the second and the third molars were not different between the skeletal Class II and III malocclusions in each age groups of both sexes. 2. The calcification stages of lower second and third molars of the skeletal Class III malocclusion are more advanced than those of the skeletal Class II malocclusion in male. 3. The clacification stages of upper second and third molars are more advanced than those of lower second and third molars in skeletal Class II malocclusion. 4. The calcification stages of lower second and third molars are more advanced than those of upper second and third molars in skeletal Class III malocclusion.