• IMMUNE NETWORK
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• v.23 no.6
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• pp.47.1-47.16
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• 2023

Scrub typhus, a mite-borne infectious disease, is caused by Orientia tsutsugamushi. Despite many attempts to develop a protective strategy, an effective preventive vaccine has not been developed. The identification of appropriate Ags that cover diverse antigenic strains and provide long-lasting immunity is a fundamental challenge in the development of a scrub typhus vaccine. We investigated whether this limitation could be overcome by harnessing the nanoparticle-forming polysorbitol transporter (PST) for an O. tsutsugamushi vaccine strategy. Two target proteins, 56-kDa type-specific Ag (TSA56) and surface cell Ag A (ScaA) were used as vaccine candidates. PST formed stable nano-size complexes with TSA56 (TSA56-PST) and ScaA (ScaA-PST); neither exhibited cytotoxicity. The formation of Ag-specific IgG2a, IgG2b, and IgA in mice was enhanced by intranasal vaccination with TSA56-PST or ScaA-PST. The vaccines containing PST induced Ag-specific proliferation of CD8⁺ and CD4⁺ T cells. Furthermore, the vaccines containing PST improved the mouse survival against O. tsutsugamushi infection. Collectively, the present study indicated that PST could enhance both Ag-specific humoral immunity and T cell response, which are essential to effectively confer protective immunity against O. tsutsugamushi infection. These findings suggest that PST has potential for use in an intranasal vaccination strategy.

• Journal of Korean Academy of Nursing
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• v.25 no.4
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• pp.653-667
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• 1995

Post - operative wound infections have been a serious problem in nursing care in the operating room and appear to be strongly related to the infection occurring during the performance of operation. The purpose of this study is to identify patterns in duration of surgical hand scrub (SHS), to evaluate the method of SHS and to examine the rate of glove perforation. Subjects for this study include 244 doctors and 169 nurses working in the operative theatre of a hospital in Seoul area. Test samples and related data were collected from this medical facility between April 1, through 15, and July 1, through 5, 1995 by the author and a staff member working in the operating room. For the study, data on the SHS of doctors and nurses were obtained at the time of operation and multiple batches of surgical gloves worn by the operating doctors were collected after each operation. The duration of SHS was measured with a stop watch and the method of SHS was evaluated according to Scoring Hand Scrub Criteria (SHS Criteria) and expressed as SHS scores. For the analysis of the data, t-test was used to compare the differences in the duration and the SHS scores of doctors and nurses, and Pearson's correlation coefficient was used to examine the relationship between the SHS duration and the SHS scores. The results of the study are summarized as follows. 1) The mean time spent in each SHS was 167 seconds in nurses, and 127 seconds in doctors. The data comparing nurses and doctors indicated that there were significant differences in Our ation of SH S between these two groups (t=5.58, p=.000). 2) The mean time spent in the first SHS was 145 seconds and that in the End SHS, 135 seconds, and there was not a significant difference in the duration of the SHS between doctors and nurses (t=1.44, P=.156). 3) The mean time spent in the SHS by OS (Orthopaedic surgery) doctors was 162 seconds, 150 seconds by NS(Neurologic surgery), 121 seconds by GS(General surgery), 94 seconds by OPH(Opthalmology) and DS(Dental surgery), 82 seconds by URO(Urology), 78 seconds by PS(Plastic surgery) and 40 seconds by ENT(Ear, Nose & Throat) These also showed a significant difference in the duration of the SHS among the medical specialities (t=4.8, P=.0001). 4) The average SHS score of the nurses was 15.2, while that of doctors was 13.1. The statistical analysis showed that t-value was 3.66, p was. 000. This indicates that the nurses actually clean their hands more thoroughly than the doctors do. 5) The average SHS score of NS doctors was 15.5, 15.3 for doctors for OPH,14.3 for OS,12.7 for GS, 12.0 for DS, 11.7 for URO, 10.1 for PS, 7.5 for ENT. Comparison of the average SHS scores from 8 specialties showed that there was a significant differences in the patterns of the SHS (F=5.08, P=.000) among medical specialties. 6) It appears that the operating personnel scrub the palms and dorsum of their hand relatively well, however, less thorough the nails and fingers. 7) The more the operating personnel spend their time in hand scrubbing, the more correctly they clean their hands(r=.6427, P<.001). 8) The overall frequencies of perforation in all post-operative gloves tested was 38 out of 389 gloves (10.3%). The perforation rate for PS was 13%, 12.1% for GS,8.8% for 05, and 3.3% for NS.

• Journal of the KSME
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• v.25 no.3
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• pp.198-203
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• 1985

제동시 균형 문제나 약간 무거운 조향력등의 전륜구동장치을 설계하기 위한 단점들은 Negative 또는 Zero scrub Radius 의 현가장치를 가능케 하는 이론적 기술적 보완 및 해결이 되고 또한 X형 브레이크 파이프 개발로 한 회로 파열에서도 더욱 안정된 제동을 할 수 있게 된다. 따라서 (1) 중. 소형 승용차에서 절대적 비중을 차지하고 있는 실내 유효공간을 훨씬 크게할 수 있는 점 (2) 후륜구동에 비해 손쉽고 갑싸게 4륜 독립 현가장치가 가능하기 때문에 승차감에서 탁월한 개선이 이루어 진다는 점 (3) 우수한 직진(방향) 안정성과 선회성능을 얻을 수 있는 점 (4) 경량화 및 전동(轉動) 손실 감소에 따른 연비 향상 등의 커다란 장점으로 전륜구동차는 기술적인 면에서 후륜구동차에 비하여 그 격을 달리하고 있으며 몇 년 전부터 모든 자동차 회사가 신규 설계 개발중인 차는 전륜구동차로 밝혀지고 있으며 사용자의 전륜구동차에 대한 선호도는 계속 크게 증가할 것으로 보인다.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.8 no.6
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• pp.80-91
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• 2005

This research aims to classify wetland types and evaluate functions of a dam lake. The case study area is Boryung lake in Boryung City. In this study was carried out based upon field surveys, drawing maps and publication, and modified-RAM which can evaluate the general functions and conservation values of wetlands. Eight functions of 2-12 variables each are analyzed for assessing the wetland functions. The analysis shows that several types of wetlands were identified, such as Palustrine/ Perennial/ Hydrophytes, Palustrine/ Perennial/ Openwater, Palustrine/ Seasonal/ Herbal, Palustrine/ Seasonal/ Shrub and Scrub, Palustrine/ Seasonal/ Hydrophye, and Riparian/ Seasonal/ Shrub in the Boryung lake. The average level of functions of the wetlands is very "HIGH", and it is recommended that prompt conservation measures should be taken.

• Journal of the Korean Institute of Telematics and Electronics A
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• v.33A no.4
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• pp.18-26
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• 1996

In this paper we propose a new dual structured tap selection algorithm for voice echo canceller in digital cellular communication system, investigating adaptive filtering algorithms for echo cancellation in long distance telephony or mobile communication system. The proposed algorithm has a two-stage processing structure that after a dispersive region in an impulse response of an echo path is found out, the tap coefficients of a short length filter are adjusted adaptively for the region, because the impuse response has a very little portion of the dispersion. Simulation results show that the proposed algorithm with 256 taps gives a performance of convergence speed superior to both full-tap normalized least mean with 256 taps gives a performance of convergence speed superior to both full-tap normalized least mean square (NLMS) and a scrub taps waiting in a queue (STWQ) algorithms by about eighty per cent, also to a tap selection algorithm by about twenty per cent. And the resutls diplay that if the more tap coefficients are used due to a long delayed dispersive zone, the proposed algorithm produces the better performance.

• Journal of Microbiology
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• v.40 no.2
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• pp.151-155
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• 2002

A Superoxide Dismutase (SOD) gene from the obligate intracellular bacterium Orientia tsutsugamushi has been cloned by using the polymerase chain reaction with degenerate oligonucleotide primers corresponding to conserved regions of known SODs. Nucleotide sequencing revealed that the predicted amino acid sequence was significantly more homologous to known iron-containing SODs (FeSOD) than to manganese-containing SODs (MnSOD). Conserved regions in bacterial FeSOD could also be seen. Isolation of the oriential SOD gene may provide an opportunity to examine its role in the intracellular survival of this bacterium.

• Journal of the Korea Furniture Society
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• v.20 no.5
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• pp.414-430
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• 2009

This paper is designed for the purpose of suggesting Figurative data applicable to modern furniture designs through doing research on Haejuban's engraving that includes excellent Figurative beauty among Korean traditional lighted-floor type furnitures. As a result of the analysis, Haejuban's(Traditional Korean dining table) engraving pattern type was mainly divided into independent patterns and combined patterns. The patterns expressed the most among them are peony patterns. The patterns expressed by the engraving mostly showed the Figurative characteristics of symmetry. The patterns shown in Haejuban's engraving wish or stand for richness, long life, lucky, fidelity, divinity, happiness, success and so on. The species of trees used for Haejuban were a total of 8 kinds such as ginkgo trees, zelkova trees, walnut trees, wild-walnut trees, chinaberry trees and other scrub trees. Ginkgo trees were used the most among them.

• Annual Conference of KIPS
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• 2019.10a
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• pp.926-927
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• 2019

본 논문은 개방형 얼굴 인식 문제를 다룬다. 이 문제는 학습되지 않는 대상에 의해 발생하는 거짓 양성 오류문제를 포함하며, 이로 인해 얼굴인식 기술을 보안 시스템에 적용하는 것을 어렵게 만든다. 본 논문에서는 이러한 개방형 얼굴 인식 문제를 효과적으로 해결하기 위해 먼저 얼굴 검증 방법으로 식별력이 강한 특징 벡터를 생성하고, 이를 바탕으로 일반적인 분류기가 아닌 추가학습과 실시간 처리가 가능한 군집화 방식의 알고리즘을 제안한다. 이 방법을 적용한 실험 결과 80 명의 얼굴이 포함된 FaceScrub 데이터 세트에서 4 명을 제외하고 학습시켰을 때 98%의 정확도와 0%의 특이도를 얻을 수 있었다.

• Korean Journal of Environment and Ecology
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• v.23 no.2
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• pp.116-126
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• 2009

This study was carried out focused an ecological characteristics and habitat management of Abeliophyllum distichum subpopulations in the Byeonsanbando National Park, Korea. Among three subpopulations of the target species in the studied area, Gamaso region are known as translocation site due to the dam construction while the wild populations which is located at both the lower terrain of the Buandaem bank and Chongnim-ni, which is designated as Natural Monument No 370, is threat due to an intensive site management likes clearance of scrub amongst the Abeliophyllum plants. Vascular plant taxa in the studied sites were summarized as 182 taxa; 65 families, 143 genera, 164 species, 17 varieties and 1 form, and Gamaso area, the lower terrain of the Buandaem and Cheongnim-ni areas are summarized as 75, 102 and 89 taxa, respectively. The plant species likes persimmon tree, paulownia tree and wild mulberry tree are dominant species in the Gamaso subpopulation, while Quercus variabilis is dominant at the lower terrain of the Buandaem. The intensive site management was applied to the Cheongnim-ni subpopulation, one of the original wild habitats of the species. The population dymanics was varied; the one or two sprouting number of stems was over 87% both at Gamaso area and the lower terrain of the Buandam, while the Cheongnim-ni subpopulation recorded as 74.8%. Also three sprouting number recorded as 16% and as 9.2% for sprouting on numbers of four to eleven. The invaded species likes Chenopodium album, Rumex obtusifolius, Phytolacca americana, Pharbitis nil, Solanum lyratum, Erigeron canadensis and Erigeron annuus, were found at the wild habitat of the species, and those invaded species grow faster than Abeliophyllum plants. Among three habitats of the target species in the studied area, the habitat which in located at the lower terrain of the Buandam and Gamaso region are known as translocated due to the dam construction, and wild subpopulation at Chongnim-ni, which is designated as Natural Monument No 370, is under threatened due to an intensive site management likes clearance of scrub amongst the Abeliophyllumplants. It is one of the evidence that Cuscuta japonica at the population indicated an intensive site management likes clearance of scrub is not proper habitat management protocol. Thus, further researches should be followed to determine the effect of canopy removal and other disturbance factors as management techniques.

• Journal of the Korean Institute of Landscape Architecture
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• v.43 no.3
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• pp.1-12
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• 2015

The purpose of this study is to offer raw data regarding landscape plantings of traditional cultural heritages by surveying and analysing the actual flora and landscape planting species distributed in Donggung Palace and Wolji Pond in Gyeongju, Korea. The results are as follows. The flora were summarized as 149 taxa including 65 families, 117 genera, 134 species, 1 subspecies, 10 varieties and 4 forms. The naturalized plants were of 18 taxa including Rumex crispus, Trifolium repens, Ailanthus altissima, Veronica persica, Senecio vulgaris, Festuca myuros and the like. Invasive species included Rumex acetosella. As a result of the analysis of chronological changes in landscape planting species, 23 taxa were planted in 1979, whereas 48 taxa were planted in 2014. Therefore, the number of these species increased by 25 taxa. The landscape planting species were of 48 taxa including 6 taxa of evergreen trees, 2 taxa of evergreen shrubs, 27 taxa of deciduous trees, 12 taxa of deciduous shrubs and 1 taxa of other. In present conditions by sections, Section A was 25 taxa, 15 taxa of Section B, 13 taxa of Section C and 29 taxa of Section D. The species planted in common were 4 taxa including Pinus densiflora, Acer palmatum, Euonymus alatus and Rhododendron yedoense for. poukhanense. The problems in the present conditions of landscape planting were volunteer species, the occurrence of scrub and vines and the spread of invasive alien plants. To restore and improve the planting landscape and facilitate tree growth, scrub, volunteer species and invasive alien plants must be removed.