• Asian Pacific Journal of Cancer Prevention
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• 제15권12호
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• pp.4903-4907
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• 2014

Background: This study aimed to identify factors associated with women's decisions to attend cervical cancer screening and to explore those linked with intention to attend in the coming year and to continue regular screening. Materials and Methods: A community based case-control study was conducted among woman 30-60 years of age in catchment area of Chatapadung Contracting Medical Unit (CCMU), networking of Khon Kaen Center Hospital, Thailand. Self-administered questionnaires were used to collect data, and in-depth interviews were then performed to explore in greater detail. Results: There were 195 participants. Only one third (32.3 %) had been screened for cervical cancer within the past 5 years. Some 67.7% reported that they had not been screened because they had no abnormal symptoms, single marital status, and no children. Only 10.6% of those never had screening intent to be screened within the next 12 months. High family income (adjusted OR=2.16, 95%CI=1.13-4.14), good attitude towards a Pap test (OR=1.87, 95%CI=1.09-4.23), and having received a recommendation from health care providers were important factors associated with decisions to attend cervical cancer screening (OR=1.73, 95%CI=1.01-4.63). From in-depth interviews, there were five reasons of their decisions to attend cervical cancer screening including yearly check-up, postpartum check-up, having abnormal symptom, encouragement by health care providers, and request from workplace. Conclusions: High family income, good attitude towards a Pap test, and receiving proper recommendation by health care providers, were important factors associated with decision to have cervical cancer screening among women 30-60 years old. Trying to enhance these factors and reduce barriers regarding screening, may increase the coverage rate for cervical cancer screening in Thailand.

• Asian Pacific Journal of Cancer Prevention
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• 제14권3호
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• pp.2141-2146
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• 2013

Cervical cancer is the third most common form of cancer that strikes Malaysian women. The National Cancer Registry in 2006 and 2007 reported that the age standardized incidence (ASR) of cervical cancer was 12.2 and 7.8 per 100,000 women, respectively. The cumulative risk of developing cervical cancer for a Malaysian woman is 0.9 for 74 years. Among all ethnic groups, the Chinese experienced the highest incidence rate in 2006, followed by Indians and Malays. The percentage cervical cancer detected at stage I and II was 55% (stage I: 21.0%, stage II: 34.0%, stage III: 26.0% and stage IV: 19.0%). Data from Ministry of Health Malaysia (2006) showed a 58.9% estimated coverage of pap smear screening conducted among those aged 30-49 years. Only a small percentage of women aged 50-59 and 50-65 years old were screened, 14% and 13.8% coverage, respectively. Incidence of cervical cancer was highest (71.6%) among those in the 60-65 age group (MOH, 2003). Currently, there is no organized population-based screening program available for the whole of Malaysia. A pilot project was initiated in 2006, to move from opportunistic cervical screening of women who attend antenatal and postnatal visits to a population based approach to be able to monitor the women through the screening pathway and encourage women at highest risk to be screened. The project was modelled on the screening program in Australia with some modifications to suit the Malaysian setting. Substantial challenges have been identified, particularly in relation to information systems for call and recall of women, as well as laboratory reporting and quality assurance. A cost-effective locally-specific approach to organized screening, that will provide the infrastructure for increasing participation in the cervical cancer screening program, is urgently required.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.5989-5994
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• 2012

Background: There is little information on longitudinal patterns of participation in faecal occult blood test (FOBT) based colorectal cancer (CRC) screening or on demographic or behavioural factors associated with participation in re-screening. The lack of an agreed system for describing participatory behaviour over multiple rounds also hampers our ability to report, understand and make use of observed associations. Our aims were to develop a system for describing patterns of participatory behaviour in FOBT-based CRC screening programs and to identify factors associated with particular behavioural patterns. Methods: A descriptive framework was developed and applied to a data extract of screening invitation outcomes over two rounds of the NBCSP. The proportion of invitees in each behaviour category was determined and associations between behaviour patterns and demographic and program factors were identified using multivariate analyses. Results: We considered Re-Participants, Dropouts, Late Entrants and Never Participants to be the most appropriate labels for the four possible observed participatory categories after two invitation rounds. The screening participation rate of the South Australian cohort of the NBCSP remained stable over two rounds at 51%, with second round Dropouts (10.3%) being balanced by Late Entrants (10.5%). Non-Participants comprised 38.7% of invitees. Relative to Re-Participants, Dropouts were older, more likely to be female, of lower SES, had changed their place of residence between offers had a positive test result in the first round. Late Entrants tended to be in the youngest age band. Conclusions: Specific demographic characteristics are associated with behavioural sub-groups defined by responses to 2 offers of CRC screening. Targeted group-specific strategies could reduce dropout behaviour or encourage those who declined the first invitation to participate in the second round. It will be important to keep first round participants engaged in order to maximise the benefit of a CRC screening program.

• Asian Pacific Journal of Cancer Prevention
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• 제15권14호
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• pp.5901-5908
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• 2014

Background: Data from BreastScreen Australia Screening and Assessment Services (SAS) for 2002-2010 were analysed to determine whether some SAS characteristics were more conducive that others to high screening performance, as indicated by high priority performance indicators and standards. Materials And Methods: Indicators investigated related to: numbers of benign open biopsies, screen-detected invasive cancers, and interval cancers, and wait times between screening and assessment. Multivariate Poisson regression was undertaken using as candidate predictors of performance, SAS size (screening volume), urban or rural location, year of screening, accreditation status, and percentages of clients from culturally and linguistically diverse backgrounds, rural and remote areas, and socio-economically disadvantaged areas. Results: Performance standards for benign biopsies and invasive cancer detection were uniformly met irrespective of SAS location and size. The interval cancer standard was also met, except in 2003 when the 95% confidence interval of the rate still incorporated the national standard. Performance indicators improved over time for: benign open biopsy for second or subsequent screening rounds; rates of invasive breast cancer detection for second or subsequent screening rounds; and rates of small cancer detection. No differences were found over time in interval cancer rates. Interval cancer rates did not differ between non-metropolitan and metropolitan SAS, although state-wide SAS had lower rates. The standard for wait time between screening and assessment (being assessed ${\leq}28$ days) was mostly unmet and this applied in particular to SAS with high percentages of culturally and linguistically diverse women in their screening populations. Conclusions: Gains in performance were observed, and all performance standards were met irrespective of SAS characteristics, except wait times to assessment. Additional descriptive data should be collected on SAS characteristics, and their associations with favourable screening performance, as these may be important when deciding on SAS design

• Journal of Preventive Medicine and Public Health
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• 제42권2호
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• pp.109-116
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• 2009

Objectives : This study was performed to evaluate the relationships between psychosocial characteristics and changes in the stage of breast cancer screening behavior. Methods : The 474 study subjects were randomly sampled from 21,459 women(age range, 40-70 years) who were eligible for the Korean National Cancer Screening Program in 2006 in Jinju, Gyeongsangnam-do. The information, including behaviors and sociodemographic characteristics, attitudes, subjective norms and self-efficacy, was collected by trained interviewers via home visits. The breast cancer screening stages were grouped as precontemplation, contemplation, action, maintenance and relapse, according to Rakowski. Results : Of the 474 women, 18.8% were in the precontemplation stage, 23.3% were in the contemplation stage, 13.1% were in the action stage, 36.6% were in the maintenance stage, and 8.2% were in the relapse stage. The distribution of stages was associated with attitude, subjective norms and self-efficacy(p for trend<0.01). To investigate the overall relationship between the variables, we conducted a linear structural equation model analysis based on the theory of planned behavior. The subjective norms and self-efficacy influenced the stage of the women's screening behavior. Conclusions : We should target on self-efficacy about the screening behavior of women by performing timely, thoughtful interventions. The support from family members, friends and other people is crucial for women to undergo breast cancer screening and to improve the breast cancer screening rate.

• 디지털융복합연구
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• 제15권1호
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• pp.329-338
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• 2017

본 연구의 목적은 소득수준에 따른 암 검진 이용 현황과 암 검진 이용에 영향을 미치는 요인을 살펴보는데 있다. 2014년 국민건강영양조사 자료를 이용하였으며, 설문에 응답한 만 40세 이상 3,393명을 분석대상자로 하였다. 분석대상자의 일반적인 특성과 생활양식, 건강관련변수, 소득수준에 따른 암 검진 이용 현황을 파악하기 위하여 기술통계를 실시하였으며, 암 검진 이용에 영향을 미치는 요인을 파악하기 위하여 로지스틱 회귀분석을 실시하였다. 연구 결과, 소득수준에 따른 암 검진 이용 현황에는 유의한 차이가 있었으며, 암 검진 이용에 영향을 미치는 변수는 성, 연령, 배우자 유무, 교육수준, 경제활동 유무, 민간보험 가입 유무, 흡연상태, 중강도 신체활동 유무, 만성질환 개수, 가구소득 수준 등으로 나타났다. 이는 소득이 낮은 계층, 만성질환자 등을 위해 디지털 시대에 적합한 보다 효과적인 암 검진 프로그램의 개발이 필요함을 시사해준다. 이러한 결과들은 향후 소득수준에 따른 암 검진 이용의 형평성과 보건의료 정책 수립에 기초자료로 의미 있게 활용되어질 수 있으리라 여겨진다.

• 한국융합학회논문지
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• 제11권5호
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• pp.289-297
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• 2020

본 연구는 학교를 기반으로 하는 학생 건강 검진 참여를 결정하는 요인들이 무엇인지를 밝히는 연구이다. 연구대상은 미국 웨스트버지니아주의 건강 관리사 6명이며, 자료 수집은 전화 인터뷰를 활용하였다. 연구 결과는 다음과 같다. 첫째, 자녀 건강에 대한 관심과 외부적인 압박, 그리고 무료 검진에 의해 동의하는 것으로 나타났다. 둘째, 건강 검진에 대한 지식 부족, 가정 통신문에 대한 무관심, 그리고 자녀의 정보 노출에 대한 불안감, 피를 뽑아야 하는 두려움이 동의를 하지 않는 것으로 나타났다. 셋째, 건강 검진의 장점으로 모든 절차가 무료로 진행된다는 점이었다. 넷째, 학부모가 동의를 결정하는 주된 결정권자이지만 때로는 자녀에게 그 결정권이 존재하고 있었다. 다섯째, 학생 주변에 존재하는 교사, 동료학생, 학교 모두 참여를 결정지을 수 있음을 확인하였다. 그러므로 가정 통신문 개선, 학부모 및 교사 교육, 무료 검사가 필요할 것이다.

• 대한영상의학회지
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• 제81권4호
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• pp.886-898
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• 2020

목적 본 연구는 부인암을 가진 여성에서 유방암의 선별검사로서의 디지털 유방단층 촬영술을 평가하였다. 대상과 방법 부인암을 가진 환자들 중 검진 목적으로 디지털 유방단층 촬영술을 촬영한 환자들을 대상으로 후향적 연구를 시행하였으며 유방암 발견율, 소환율, 민감도, 특이도, 양성예측도를 계산하였다. 양성예측도 1은 모든 양성 선별검사 중 1년 이내에 조직 검사에서 유방암을 진단받은 환자의 백분율로 정의되었다. 양성예측도 2는 진단 검사에서 조직검사의 필요 판정을 받은 후(그리고 선별 검사에서 Breast Imaging Reporting and Data System 카테고리 4, 5를 받은 후) 1년 이내에 조직검사에서 유방암을 진단받은 환자의 백분율로 정의되었다. 양성예측도 3은 실제로 조직검사를 시행 받은 환자 중 1년 이내에 조직검사에서 유방암을 진단받은 환자의 백분율로 정의되었다. 검진으로 발견된 암의 각 경우에 대해 환자의 나이, 부인암의 종류, 유방 밀도, 영상의 특징, 최종 Breast Imaging Reporting and Data System 평가, 조직학적 유형, T 및 N 병기, 분자아형 및 Ki-67 지수를 분석했다. 결과 전체 508명 중 7개의 유방암이 발견되었으며 유방암 발견율은 1000건 당 암 13.8이었다. 민감도는 100%, 특이도는 83.2%였으며 위음성률은 1000건 당 0이었다. 양성예측도 1, 양성예측도 2, 양성예측도 3은 각각 7.7, 31.8, 31.8이었으며 소환율은 17.9%였다. 결론 본 연구에서 디지털 유방단층 촬영술은 높은 유방암 발견율, 높은 민감도, 높은 양성예측도를 보이며 T, N 병기가 낮은 초기 암에 대해 높은 발견율을 보였다. 따라서 부인암 환자와 같은 고위험군에서 유방암의 선별검사로서 디지털 유방단층 촬영술이 유용할 수 있다.

• 센서학회지
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• 제29권2호
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• pp.100-104
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• 2020

Thus far, several in vivo biosensing platforms have been proposed to measure the mechanical contractility of cultured cardiomyocytes. However, the low sensitivity and screening rate of the developed sensors severely limit their practical applications. In addition, intensive research and development in cardiovascular disease demand a high-throughput drug-screening platform based on biomimetic engineering. To overcome the drawbacks of the current state-of-the-art methods, we propose a high-throughput drug-screening platform based on 16 functional high-sensitivity well plates. The proposed system simulates the physiological accuracy of the heart function in an in vitro environment. We fabricated 64 cantilevers using highly flexible and optically transparent silicone rubber and placed in 16 independent wells. Nanogrooves were imprinted on the surface of the cantilever to promote cell alignment and maturation. The adverse effects of the cardiovascular drugs on the cultured cardiomyocytes were systematically investigated. The 64 cantilevers demonstrated a highly reliable and reproducible mechanical contractility of the drug-treated cardiomyocytes. Real-time high-throughput screening and simultaneous evaluation of the cardiomyocyte mechanical contractility under multiple drugs verified that the proposed system could be used as an efficient drugtoxicity test platform.

• 대한인간공학회지
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• 제28권4호
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• pp.91-99
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• 2009

A visual stress may provoke migraine, cephalalgia, intervene a long term reading and learning capability and reduce the productivity of a laborer who uses computer for a good while. In this study, a web based screening tool for visual stress was developed, it applied to 72 visually normal young persons in parallel with traditional questionnaire about symptoms of visual stress. To estimate visual stress, It is proposed to measure difference of visual search time of Han Gul characters as targets between visual stressful pattern and non-visual stressful pattern as global background of characters. As a result of test, 5 subjects were screened whose mean visual search time in the stressful pattern with 6 CPD spatial frequency increase significantly more than in none stressful pattern(t-test, one-tailed, p=$1.0407\times10^{-11}$). 2 of them were diagnosed as mild visual stress syndrome in the clinic. None had visual distortion and 50% of subjects had visual discomfort in results of the questionnaire. Correlation between visual search time increase rate and normalized number of visual discomfort may be slight(C. coefficient=0.1355). This study may contribute as a basic research for screening person with migraine, visual reading disabilities and VDT syndrome. It is required to apply the test to visual reading disabilities, migraine with visual distortion and/or visual discomfort as well as normal person for higher reliability of the screening tool.