• 임상간호연구
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• 제22권1호
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• pp.56-67
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• 2016

Purpose: The purpose of this study was to develop an evidence-based nursing protocol for peripheral intravenous catheter management in hospitalized children. Methods: The preliminary protocol of this study was developed based on domestic and foreign guidelines, research, a survey and an analysis of medical records in a university hospital. It is a methodological research to develop evidence-based nursing protocol of peripheral intravenous catheter management verified by content validity by a group of specialists and users. Results: The specialists' verification of validity in the preparatory protocol had a CVI level of 0.94 and the propriety and conveniency of users had an average of $3.0{\pm}0.52$. The final evidence-based nursing protocol was composed of 5 areas (education, dressing and fixation, maintenance and replacement, observation and record, and coping to complication) with 46 specific recommendations. Conclusion: Based on domestic and foreign research and guidelines verified by specialists and users, the findings in this study provide a simple, applicable and evidence-based nursing protocol for peripheral intravenous catheter management in hospitalized children. By the clinical application of this protocol, nurse tasks in managing peripheral intravenous catheter can be performed with more scientific evidence and be standardized.

• 한국과학교육학회지
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• 제40권1호
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• pp.29-40
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• 2020

본 연구의 목적은 한 고등학교 과학 교사(E 교사)가 약 1년 3개월간 교사공동체 탐구에 참여하며 어떻게 과학적 모델링에 관한 이해와 실행을 변화시켜나갔는지를 탐색하는 것이었다. 상황 학습 관점을 기반으로 본 연구에서는 E 교사의 사회적 상호작용들로부터 모델링에 관한 그녀의 프레임들을 탐색하였다. E 교사는 1년 3개월간 총 6회의 "스튜디오"라는 교사 연수에 참여해 같은 학교의 과학 교사들과 연구자들, 코치들과 협력하였다. 매 스튜디오에서 참여자들은 함께 모델링 기반 수업을 계획하고, 실행하고, 그에 관해 반성하였다. 본 연구에서는 먼저 E 교사가 수업을 진행한 2회차, 6회차 스튜디오에 초점을 맞추어, E 교사의 교사공동체 및 교실 상호작용으로부터 드러난 모델링에 관한 그녀의 프레임들을 질적으로 탐색하고, 그로부터 E 교사의 이해와 실행에 변화가 있었는지 탐색하였다. 다음으로, 교사공동체 탐구가 E 교사의 이해와 실행 변화에 어떻게 영향을 미쳤는지 탐색하기 위하여, 1-6회차 스튜디오에서 진행된 교사공동체 탐구가 질적으로 분석되었다. 연구 결과, 2회차 스튜디오에서 E 교사는 과학적 모델링을 학생들이 활동지에 정답을 채워 넣는 활동으로 보고 있었다. 반면 6회차 스튜디오에서 E 교사가 드러낸 과학적 모델링에 관한 프레임들은 그녀가 모델링을 학생들이 협력을 통해 증거를 사용하여 자연현상에 관한 설명을 구성하는 과정으로 보고 있었음을 보여주었다. E 교사가 속한 교사공동체는 모델링 기반 교수를 발전시키고자 하는 목표를 바탕으로, 매 스튜디오에서 학생들의 모델링을 돕고, 학생들의 설명과 추론을 분석하였다. 또한 그들은 여러 스튜디오들에 걸쳐 탐구 초점들과 교수 실행들을 구체화시키고 발전시켜나갔다. 이러한 공동체 탐구의 초점들은 E 교사의 과학적 모델링에 관한 이해와 실행 변화에 반영되었다. 본 연구의 결과는 교사공동체 탐구나 교사 전문성 발달을 지원하고자 하는 연구자, 실행가들에게 유용한 정보를 제공할 수 있다.

• Journal of Nutrition and Health
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• 제46권3호
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• pp.226-238
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• 2013

Omega-3 polyunsaturated fatty acids are essential fatty acids because humans cannot synthesize them de novo and must obtain them in their diet. Fish and fish oil are rich sources of omega-3 fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Significant evidence of the beneficial role of dietary intake of omega-3 fatty acids in blood flow has been reported and putative mechanisms for improvement of blood flow include anti-thrombotic effects, lowered blood pressure, improved endothelial function, and anti-atherogenic effects. Edible oils containing omega-3 fatty acids were registered as functional ingredients in the Korea Health Functional Food Code. Although omega-3 fatty acids have been evaluated by the Korea Food and Drug Administration (KFDA) based on scientific evidence, periodic re-evaluation may be needed because emerging data related to omega-3 fatty acids have accumulated. Therefore, in this study, we re-evaluated scientific evidence for the effect of omega-3 fatty acids as a functional ingredient in health functional food on improvement of blood flow. A comprehensive literature search was conducted for collection of relevant human studies using the Medline and Cochrane, KISS, and IBIDS databases for the years 1955-2012. Search keywords were used by combination of terms related to omega-3 fatty acids and blood flow. The search was limited to human studies published in Korean, English, and Japanese. Using the KFDA's evidence based evaluation system for scientific evaluation of health claims, 112 human studies were identified and reviewed in order to evaluate the strength of the evidence supporting a relation between omega-3 fatty acids and blood flow. Among 112 studies, significant effects on improvement of blood flow were reported in 84 studies and the daily intake amount was ranged from 0.1 to 15 g. According to this methodology of systematic review, we concluded that there was possible evidence to support a relation between omega-3 fatty acid intake and blood flow. However, because inconsistent results have recently been reported, future studies should be monitored.

• 한국초등과학교육학회지:초등과학교육
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• 제28권2호
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• pp.161-177
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• 2009

This study aims to explore how teachers construct scientific explanation during instructional practices to help students' scientific inquiry. Before investigating teachers' classroom practices, elementary school science curriculum was examined to identify scientific concepts, particularly in earth science. Then, a total of six teachers' scientific explanation in actual teaching practices was analysed focusing on a) explanation of scientific concepts; b) rationale for scientific explanation; c) connection between scientific explanation and everyday explanation. The findings are as follows. First, the science curriculum provides $1{\sim}2$ main scientific concepts per unit, which are mostly appeared in the unit title. Those concepts and sub-concepts are not explicitly described but embedded in students' inquiry activities. Second, the teachers explain scientific concepts and discuss the rationale behind the scientific explanation, but rarely connect scientific explanation to everyday explanation. Also, the level of scientific explanations is low remaining level 1 or 2, not reaching 3, the highest level. Based on the results, the study suggests a) teachers need to provide explicit and clear explanations about scientific concepts; b) teachers are required to connect scientific explanation and everyday explanation; c) the level of teachers scientific explanation should be elevated by using an evidence, reasoning and claim, the components of scientific explanation as well as introducing new scientific concepts and inquiry activities.

• 한국지구과학회지
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• 제33권5호
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• pp.459-466
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• 2012

This study aimed to investigate the characteristics of pre-service elementary teachers' understanding about scientific inquiry in terms of designing exploration and reasoning that is used to formulate explanations based on evidence. The research context was an open inquiry with using the Science Writing Heuristic (SWH) template in which participant students were not provided with inquiry questions. As data, lab. 39 pre-service elementary teachers participated in this study while taking their science methods course. Analyses of the reports were framed by the cognitive processes of inquiry (Chinn and Malhotra, 2002) and each report was coded and analyzed by the framework of inquiry (Tytler and Peterson, 2004). Results showed that groups' works that utilized the SWH template encouraged the participants to interact each other about scientific inquiry. They came up with more relevant and testable questions for their scientific inquiry. It implicates that children will be able to have chances of testing their own questions more properly by using the SWH template in science classes just as the participants did in this study. The use of the SWH template would help pre-service teachers to teach appropriately how to test inquiry questions to their students in the future. Discussion was made to figure out the characteristics or Korean pre-service elementary teachers' understanding about scientific inquiry.

• Nutritional Sciences
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• 제7권3호
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• pp.165-173
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• 2004

This paper reviews the available published literature on the antioxidant, anti-inflammatory, and COX-2 inhibition properties of phycocyanin from Spirulina. The potential application of for the prevention and mitigation of such radical-induced chronic diseases like cancer and heart disease, and age-related degenerative diseases like Alzheimer＇s disease, Parkinson＇s disease, diabetes and other conditions are discussed based on the available evidence.

• 대한한의학회지
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• 제44권3호
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• pp.189-200
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• 2023

Objectives: The purpose of this study is to analyze the current state of quantitative literature evidence for the prescription of 56 herbal medicines covered by health insurance that have been studied in Korea for the past 30 years, to evaluate the reliability of the evidence, and to find out the research direction of herbal medicine prescription in the future. Methods: 56 kinds of herbal medicine prescriptions were searched in domestic literature search databases OASIS, DBpia, and overseas PubMed, classified into chemistry, toxicity, cells, animals, clinical cases, and clinical trial studies, and built into an EBM pyramid structure. Results: When classified according to research contents, there were 61 cases (7.5%) of physicochemical analysis to identify constituent substances, 80 cases (9.8%) of toxicity evaluation, and 672 cases (82.7%) of efficacy evaluation. The efficacy evidence was classified according to the evidence-based medical pyramid structure: 196 cell trials (29.1%), 372 animal trials (55.4%), 89 case and case reporting series (13.3%), 7 comparative case studies (1.1%), and 8 randomized control clinical trials (1.2%). In the pyramid composition, the basis for the validity of 56 kinds of herbal medicines prescribed was 568 cases (84.5%) in cell and animal units, which could not be said to be highly reliable. There was no relationship between the ranking of quantitative literature evidence for herbal medicine prescriptions and the ranking of salary administration. Conclusions: In an era that continues to require scientific evidence for herbal medicine, traditional herbal medicine should secure the basis for safety validity even for the 10th most frequent prescription among 56 herbal medicine prescriptions for consumers. In particular, traditional herbal medicine should increase the quantitative and qualitative level of case reports on related herbal medicine prescriptions, focusing on each clinical society, and move toward comparative case studies and randomized clinical trial so that traditional herbal medicine is positioned as Evidence-based medicine.

• 대한화학회지
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• 제62권2호
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• pp.137-147
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• 2018

본 연구는 과학 관련 사회적 쟁점(Socio-Scientific Issues, SSI)의 국내 프로그램 123개를 SSI 준거틀에 따라 분석하였다. 준거틀은 프로그램의 주제, 학교급, 도입, 과학적 증거, 사회적 내용, 과학적 지식의 사용, 갈등 수준, 평가와 성찰 등으로 구성된다. 분석한 결과에 따른 결론은 다음과 같다. 첫째, 우리나라 SSI 프로그램은 초등학교급 프로그램이 가장 많았고, 중학교급 프로그램이 상대적으로 적게 나타났다. 둘째, SSI 프로그램의 도입은 실제 상황과 픽션과 논픽션 상황이 주된 것으로 나타났고, 논쟁과 갈등이 포함된 상황은 10% 미만으로 나타났다. 셋째, SSI 프로그램은 과학적 증거에 기반하지만 개인의 가치, 인식 등에 따라 영향을 받는 내용이 주로 나타났다. 넷째, SSI 프로그램의 사회적 내용은 윤리/도덕/가치, 정치/사회생활/경제, 환경 내용이 주로 개발되었다. 다섯째, SSI 프로그램에서 과학적 지식의 사용은 과학적 의사결정, 과학적 비판적 사고, 정보 탐색이 주로 나타났다. 그러나 과학 탐구, 위험평가, 비용 효과는 10% 미만으로 나타났다. 과학적 탐구는 과학교육의 핵심이며, 과학과 교육과정의 핵심역량이다. SSI 교육을 통해 학생들의 다양한 이해당사자의 관점을 경험하고, 평가하고, 반성하는 학습 경험을 제공해야 한다.

• Environmental Analysis Health and Toxicology
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• 제31권
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• pp.1.1-1.13
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• 2016

Objectives To investigate the accuracy and scientific validity of the current very low risk factor for hereditary diseases in humans following exposures to ionizing radiation adopted by the United Nations Scientific Committee on the Effects of Atomic Radiation and the International Commission on Radiological Protection. The value is based on experiments on mice due to reportedly absent effects in the Japanese atomic bomb (A-bomb) survivors. Methods To review the published evidence for heritable effects after ionising radiation exposures particularly, but not restricted to, populations exposed to contamination from the Chernobyl accident and from atmospheric nuclear test fallout. To make a compilation of findings about early deaths, congenital malformations, Down's syndrome, cancer and other genetic effects observed in humans after the exposure of the parents. To also examine more closely the evidence from the Japanese A-bomb epidemiology and discuss its scientific validity. Results Nearly all types of hereditary defects were found at doses as low as one to 10 mSv. We discuss the clash between the current risk model and these observations on the basis of biological mechanism and assumptions about linear relationships between dose and effect in neonatal and foetal epidemiology. The evidence supports a dose response relationship which is non-linear and is either biphasic or supralinear (hogs-back) and largely either saturates or falls above 10 mSv. Conclusions We conclude that the current risk model for heritable effects of radiation is unsafe. The dose response relationship is non-linear with the greatest effects at the lowest doses. Using Chernobyl data we derive an excess relative risk for all malformations of 1.0 per 10 mSv cumulative dose. The safety of the Japanese A-bomb epidemiology is argued to be both scientifically and philosophically questionable owing to errors in the choice of control groups, omission of internal exposure effects and assumptions about linear dose response.

• 한국과학교육학회지
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• 제34권5호
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• pp.479-490
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• 2014

이 연구는 과학교육에서 의사소통을 위해 글쓰기와 논의를 활용한 논의-기반 모델링 전략의 개발을 목적으로 하였다. 논의-기반 모델링 전략은 모델링의 목적인 의사소통을 위해 자신이 만든 모델을 논의와 글쓰기를 통해 과학적 언어를 사용하여 스스로 정리하거나 표현하고, 다른 사람의 의견을 듣고 교환하는 과정을 통해 모델을 평가하고 수정하는 일련의 과정을 의미한다. 이 전략은 과학교육에서 모델링에 어려움을 느끼는 학생과 교사를 지원하기 위한 것으로 다음 네 가지 요소의 발달에 초점을 맞추었다. 첫째 여러 문제 상황을 관찰하여 문제를 연관지어 인식하는 문제인식이다. 둘째는 과학적 설명을 위해 충분한 과학개념을 구조화하여 제시하는 과학개념 구조화이며, 셋째는 주장에 대해 적절한 표상을 증거로 제시하는 주장-증거 적절성이다. 마지막은 증거제시에서 다양한 표상의 사용과 이 표상들을 전환하고 통합하는 다중표상 지수이다. 이 네 가지 요소의 발달을 위해 세 가지 stage를 구성하였다. '인지 과정'은 다중표상에 대한 이해를 위한 것이고, '해석 과정'은 다중표상 활동을 통해 증거 제시의 중요성을 인식하는 것이며, '적용 과정'은 학생들이 논의-기반 모델링을 직접 접해보는 것이다. 이 적용 과정에서는 질문 또는 문제 만들기-실험 설계 및 수행하기-관찰 통한 조사하기-자료의 분석 및 해석하기-임시 모델 설계하기-논의하기-되돌아보기-모델 평가하기-모델 수정하기의 아홉 개의 단계로 이루어진다. 논의-기반 모델링 전략은 학생들이 자신이 설계한 임시모델을 다른 사람과 공유하기 위해 증거를 바탕으로 발표하고 반박하는 논의과정을 통해 증거 제시의 필요성을 인식할 수 있다. 논의과정 후 학생들은 주장과 증거를 다중표상으로 나타내는 것에 대해 되돌아보는 과정을 거치면서 주장-증거 적절성을 높이게 된다. 또한 모델을 평가하기 위한 기준을 만들고, 이를 바탕으로 자신의 모둠이나 다른 모둠의 모델을 평가하고 그 결과를 피드백 받으면서 수정하게 된다. 이러한 일련의 과정을 거치면서 관찰한 자연세계의 현상에 대한 자신의 설명체계를 만듦으로써 과학적 지식을 형성할 수 있는 기회를 제공받을 수 있다.