• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.134.2-135
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• 2002

• 대한약학회:학술대회논문집
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• 대한약학회 2000년도 NEW STRATEGY FOR DRUG DEVELOPMENT IN POST-GENOMIC ERA(대한약학회)
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• pp.247.2-247.2
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• 2000

• 대한약학회:학술대회논문집
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• 대한약학회 2001년도 Proceedings of International Convention of the Pharmaceutical Society of Korea
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• pp.166.1-166.1
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• 2001

• 약학회지
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• 제52권6호
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• pp.452-465
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• 2008

Hair analysis for drugs of abuse offers the crucial potential advantage when compared to urine, such as the longer time window of drug intake, which makes retrospective investigation of chronic and/or past consumption. This paper reviews the physiological basis of hair growth, mechanism of drug incorporation, analytical methods, result interpretation and practical application of hair analysis. Moreover, to facilitate the court's decision regarding specific circumstances surrounding the crime, this review demonstrated that the results of hair analysis not only should be admitted as scientific evidence of drug use but also could legally improve reliability of the evidence.

• Environmental Analysis Health and Toxicology
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• 제20권4호통권51호
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• pp.297-302
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• 2005

The purpose of this study was to provide the standard method for the analysis of organophosphorous pesticides such as chlorpyrifos, diazinon, malathion and parathion in blood. We performed method validation for these pesticides in blood according to EURACHEM (A focus For Analytical Chemistry in Europe) guide. For the analysis of the pesticides, we used solid-phase extraction ,column (Waters Oasis $HLB^{(R)}$. After the extraction, the supernatants were evaporated to dryness under the nitrogen stream. They were analyzed by gas chromatography/mass spectrometry (GC/MS) after reconstituting with ethanol. Terbufos was used as an internal standard. To validate this method, we performed verification procedures with the following parameters: selectivity, linearity of calibration, accuracy, precision, limit of detection and quantification. Validation data according to Eurachem guide were adequate for our purpose for the analysis of chlorpyrifos, diazinon, malathion and parathion in blood.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.111.2-112
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• 2003

Dextromethophan and carisoprodol have been abused to obtain a hallucination for longer than 10 years in Korea. Due to their seriousness of abuse liablility, recently government decided to control them as a psychotropic agents. As these are controlled, it is necessary for us to establish the analysis of these medicine and their metabolites in hair to prove the abuse of these drugs. This study is described for the determination of dextrometorphan and carisoprodol in hair. (omitted)

• 한국항해학회지
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• 제4권2호
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• pp.7-38
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• 1980

Nowadays researchers attach a great importance to the problems concerned with scientific information in the field of science and engineering. There are some reasons for it, that is, ⅰ) the amount of scientific information increases in proportion to the activities of scientists and engineers, so it is difficult to pick up a real valuable information ⅱ) it becomes more important to use a variety of information in proportion to the spread ofthe branch of science ⅲ) since the medium of scientific information is mostly technical papers, it is very difficult to mechanically transact these papers and to keep all documents and scientific informations for a long time. To cope with these difficult situations, many technical skills have been developed, for example, data-base, automatic information retrieval, micro-film and so on. But there are comparatively few investigation on the matter how the researchers who are users and producers think about the systematization of scientific information usage, so this paper investigates the thought and information needs of researchers, and proposes a basis of a method for systematization of scientific information usage. The author inspects the actual conditions of scientific information, reconsider the method which has been used and investigates the matter of how researchers whose interest is closely related to the study of marine affairs think about problems of scientific information usage by thequestionarie of Fuzzy-DEMATEL method. Also, FSM which is method for structuring hierarchy for the several complex problems on the basis of fuzzy sets theory is adopted as a tool of analysis. We can understand the key problems and make a story to solve the systematization of scientific information usage from the results of the analysis and those results will be directly applicable to construct a new system for scientific information usage.

• 한국초등과학교육학회지:초등과학교육
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• 제37권3호
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• pp.267-284
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• 2018

This study analyzed the types of scientific humors made by scientifically-gifted elementary school students and their perceptions of making scientific humor. For this, 77 students from $4^{th}$ to $6^{th}$ graders of gifted science education center in Seoul National University of Education were selected. Scientific humors made by the students were analyzed according to the number and types. Their perceptions of making scientific humor were also analyzed through a questionnaire and group interviews. The analysis of the results revealed that most of scientifically-gifted students made more than 2 scientific humors, and the number of scientific humor for each students varied from 0 to 11. The most types they made were the descriptive type and the pun using pronunciation type, but they made various types without any special type to be biased. And They made more the dialogue type than the narrative type, especially the riddle type. They used scientific knowledge that preceded the knowledge of science curriculum in their grade level over two or more years. The scientific knowledge of chemistry was used more than physics, biology, earth science and combination field. The name utilization type was more than the characteristic utilization type and the principle utilization type. Scientific humors in the everyday situation were more than humors in artificial situation. The students had various positive perceptions in making scientific humor such as increase of scientific knowledge, increase of various thinking abilities, deep understanding of science concept and principle, increase of interest and motivation about science and science learning, and increase on sense of humor. They had also some negative perceptions related to difficulties in the process of making scientific humor, lack of fun, and lack of time in the class.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.219.3-219.3
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• 2003

We describe here solid-extraction and derivatisation methods of ${\beta}$-adrenoceptor blocking drugs used for the treatment of various cardiovascular disorders such as hypertension, angina pectoris and cardiac arrhythmia: propranolol, metoprolol, sotalol, timolol, oxprenolol, alpranolol, atenolol, pindolol. Solid-extraction and derivatisation methods are described involving the use of Bond Elut Certify cartridges, MSTFA and MBTFA. Gas chromatographic-mass spectrometry analysis(GC/MS) was carried out select-ion monitroing mode. (omitted)

• 한국과학교육학회지
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• 제40권1호
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• pp.41-50
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• 2020

과학 개념에 대한 이해를 언어학적 관점에서 바라보면 학생들이 과학 개념어에 대한 깊고 정교한 이해와 더불어 정확하게 사용할 수 있는 능력을 길러주는 것이 매우 중요하다. 본 연구에서는 지금까지 과학 교육에서 과학 개념어에 대한 생산적 지식 교육의 기틀이 잘 마련되어 있지 않음에 주목하고, 과학 개념을 구성하고 있는 단어들 사이의 관계를 생산적이고 효과적으로 교육할 수 있는 방안을 탐색함으로써 과학 개념어의 생산적 지식 교육의 기틀을 제공하고자 하였다. 이를 위해 첫째, 몇 가지의 계량 언어학적 텍스트 분석 방법을 이용하여 과학 교과서 텍스트로 부터 과학 개념을 구성하고 있는 단어들과 그들 사이의 관계를 추출하고, 둘째, 각 방법의 결과로 추출된 단어 관계의 의미를 정성적으로 살펴본 뒤, 셋째, 이를 이용하여 과학 개념어의 생산적 지식 향상에 도움을 줄 수 있는 쓰기 활동 방법을 제안해 보았다. 중학교 1학년 과학교과서 '힘과 운동' 단원 텍스트를 클러스터 분석, 공기 빈도 분석, 텍스트 네트워크 분석, 그리고 워드임베딩의 네 가지 계량 언어학적 분석 방법을 사용하여 분석해 보았다. 연구 결과 첫째, 클러스터 분석 결과를 활용하여 문장 완성하기 활동을 제안하였다. 둘째, 공기 빈도 분석 결과를 이용한 빈 칸 채우기 활동을 제안하였다. 셋째, 네트워크 분석 결과를 이용하여 소재 중심 글쓰기 활동을 제안하였다. 넷째, 워드임베딩을 이용한 학습 중요 단어 목록 작성을 제안하였다.