• Journal of Korean Ophthalmic Optics Society
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• v.16 no.3
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• pp.319-325
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• 2011

Purpose: The relativity of factors between low vision and socioeconomic status were investigated. This study represented the preliminary data for establishment of public eye health policy. Further, this report would encourage people to change the social attitudes about the eye health equity of the nation. Methods: The number of people (2,514 people) who have been tested the forced visual activity were examined as it was referred the Korea National Health and Nutrition Examination Survey (KNHNE) of 2009-year data. The prevalence rate of low vision of subjects which are related with house income, education level and occupations were conducted with ttest and chi square test. Besides, the Binominal Logistic Regression was conducted to measure the odds ratio of the subjects. Results: In outline, the prevalence rate of low vision was high with low house income, low education level and low function. The odds ratio represented that 2.77(95% CI, 1.72-4.47) at low house income group and 4.02(95% CI, 1.75-9.23) at the case of below primary school education level. Moreover, the results of unemployed group showed 3.65(1.14-11.68) from the odds ratio measurement. Conclusions: The eye health policy need be instituted which is broad and meticulous support to ease the eye health equity of low eye sight patients. For instance, the education about eye health, examination business of eye disease, and education of assistant units which are useful for low eye sight would suggest practical solution.

• Current Research on Agriculture and Life Sciences
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• v.4
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• pp.163-168
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• 1986

This study was carried out to compare the conditions of Korean and Japanese forestry. Two countries were appeared same trend in forestry condition, so our forestry in future can be estimated with compared Japanese forestry, but the results obtained are as follows ; 1) The average forest area per capita of the world, Japan and Korea are 0.9, 0.23 and 0.16 ha, respectively, this means that Korean forest area is not sufficient. The growing stock of forest per capita is $22.5m^3$ in Japan and $3.9m^3$ in Korea, but timber consumptions per capita are $1m^3$ in Japan and $0.2m^3$ in Korea. Those mean that both countries have not a plentiful resource of forestry. 2) The forestry production activity becomes gradually stagnation. Both in Korea and Japan, the reforestation and stumpage felling area show gradually decreasing tendency, the artificial forest ratio of total forest area is, at present, 28% in Korea and 40% in Japan. 3) In forestry demand aspect, the ratio of imported timber is 79% in Korea and 62.4% in Japan. Because the price index of timber is lower than the general price index, the dullness of forestry-related industries is expected in future. 4) The forestry labour supply has gradually difficulty because of the reduction in farming labour. 5) The managements of national forests show deficit operation, at present, both in Korea and Japan. The results above mentioned are derived form the poor forest resources, therefore, it is considered that rather more and continuous investment is necessary, but also forestry should be invested in the territorial conservation aspect.

• Journal of Plant Biotechnology
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• v.48 no.3
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• pp.124-130
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• 2021

Nitrate is an important nutrient and signaling molecule in plants that modulates the expression of many genes and regulates plant growth. In this study, we cover the research status of transcription factors related to the control of gene expression by nitrate signaling in higher plants. Nitrate reductase is a key enzyme in nitrogen assimilation, as it catalyzes the nitrate-to-nitrite reduction process in plants. A variety of factors, including nitrate, light, metabolites, phytohormones, low temperature, and drought, modulate the expression levels of nitrate reductase genes and nitrate reductase activity, which is consistent with the physiological role if. Recently, several transcription factors controlling the expression of nitrate reductase genes have been identified in higher plants. NODULE-INCEPTION-Like Proteins (NLPs) are transcription factors responsible for the nitrate-inducible expression of nitrate reductase genes. Since NLPs also control the nitrate-inducible expression of genes encoding the nitrate transporter, nitrite transporter, and nitrite reductase, the expression levels of nitrate reduction pathway-associated genes are coordinately modulated by NLPs in response to nitrate. Understanding the function of nitrate in plants will be useful to create crops with low nitrogen use.

• Korean Journal of Remote Sensing
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• v.37 no.6_1
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• pp.1647-1656
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• 2021

In order to reduce the spread of infection due to COVID-19, South Korea has established a four-step social distancing standard and implemented it by changing the steps based on the rate of confirmed cases. The implementation of social distancing brought about a change in the amount of activity of citizens by limiting social contact such as movement and gathering of people. One of the data that can intuitively confirm this is Night Time Light (NTL). NTL is a variable that can measure the size of the national economy measured using lights captured by satellites, and can be used to understand people's social activities during the night. The NTL visible data is obtained via the Visible Infrared Imaging Radiometer Suite (VIIRS) Day-Night Band (DNB) onboard the Suomi National Polar-orbiting Partnership (S-NPP) satellite. 1023 of Suomi data from 1 January 2019 until 26 October 2021 were collected to generate time series of NTL radiance change over Seoul to analyze the correlation with social distancing policy. The results show that implementing the level of social distancing generally decreased the NTL radiance both in spatial disparities and temporal patterns. The higher level of policy, limiting human activities combined with the low number of people who have been vaccinated and the closure of various facilities. Because of social distancing, the differences in human activities affected the nighttime light during the COVID-19 pandemic, especially in Seoul, South Korea. Therefore, this study can be used as a reference for the government in evaluating and improving policies related to efforts reducing the transmission of COVID-19.

• Korean Journal of Plant Resources
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• v.34 no.5
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• pp.433-442
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• 2021

The fermented red ginseng by microorganism is known to increase pharmacological activity in vivo. To evaluate the bioavailablity of red ginseng fermented by probiotics, we conducted the pharmacokinetic study of ginsenoside Rb1, Rd and total ginsenosides (TG, ginsenosides Rb1 + Rd + Rg1 + F2 + Rg3 + compound K) in BALB/C mice. The AUC value of ginsenoside Rb1 in mice serum administered with 600mg/kg drugs showed 21.93 ± 14.68 ng·h/mL (RGw, water extract), 275.211 ± 110.04 ng·h/mL (RGe, 50% ethanol extract) and 404.91 ± 162.57 ng·h/mL (fRGe, fermented red ginseng extract). Analysis of ginsenoside Rd also showed a higher ACU value in fRGe than in RGw or RGe. And the AUC value of total ginsenosides in mice serum treated with 600 mg/kg were observed 42.12 ± 23.44 ng·h/mL (RGw), 321.44 ± 133.5 ng·h/mL (RGe) and 537.33 ± 229.01 ng·h/mL (fRGe), respectively. C_max value of ginsenoside Rb1 in mice administered with 600mg/kg were observed 3.67 ± 3.34 ng/mL (RGw), 23.27 ± 8.81 ng/mL (RGe) and 25.52 ± 7.29 ng/mL (fRGe). These results can be considered that the fermented red ginseng has more bioavailability than that of unfermented red ginseng. In quantitative analysis of the inflammation-related cytokines IL-1β and TNF, no significant difference was found between the fermented red ginseng (fRGe) and the red ginseng (RGe).

• Journal of Microbiology and Biotechnology
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• v.29 no.7
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• pp.1165-1176
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• 2019

Botulinum neurotoxins (BoNTs), produced by Clostridium botulinum, are the most toxic substances known. However, the number of currently approved medical countermeasures for these toxins is very limited. Therefore, studies on therapeutic antitoxins are essential to prepare for toxin-related emergencies. Currently, more than 10,000 Halla horses, a crossbreed between the native Jeju and Thoroughbred horses, are being raised in Jeju Island of Korea. They can be used for equine antitoxin experiments and production of hyperimmune serum against BoNT/A1. Instead of the inactivated BoNT/A1 toxoid, Halla horse was immunized with the receptor-binding domain present in the C-terminus of heavy chain of BoNT/A1 (BoNT/A1-HCR) expressed in Escherichia coli. The anti-BoNT/A1-HCR antibody titer increased rapidly by week 4, and this level was maintained for several weeks after boosting immunization. Notably, $20{\mu}l$ of the week-24 BoNT/A1-HCR(-immunized) equine serum showed an in vitro neutralizing activity of over 8 international units (IU) of a reference equine antitoxin. Furthermore, $20{\mu}l$ of equine serum and $100{\mu}g$ of purified equine $F(ab^{\prime})_2$ showed 100% neutralization of 10,000 $LD_{50}$ in vivo. The results of this study shall contribute towards optimizing antitoxin production for BoNT/A1, which is essential for emergency preparedness and response.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.5
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• pp.118-127
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• 2019

This study was conducted to provide data for the development of health program to promote patient safety nursing activities by analyzing the effect of perception of importance of patient safety management, perceptions of patient safety culture and organizational communication on patient safety nursing activities in small & medium hospital nurses. Data collection was conducted from February 8 to 15, 2019. A total of 202 questionnaires were administered to nurses who have worked for more than six months in three small and medium hospitals. The perception of importance of patient safety management of the subjects was $3.60{\pm}.49$, perception of patient safety culture was $3.39{\pm}.41$, organizational communication was $3.29{\pm}.45$ and patient safety nursing activities was $4.08{\pm}.50$. The patient safety nursing activities was related to perception of importance of patient safety management(r=.597, p<.001), perception of patient safety culture(r=.626, p<.001), organizational communication(r=.559, p<.001), there was a significant positive correlation. Perception of importance of patient safety management(${\beta}=.258$, p=.001), perception of patient safety culture(${\beta}=.323$, p<.001) and organizational communication(${\beta}=.160$, p=.044) had a significant effect on patient safety nursing activities(F=53.067, p<.001). The explanatory power of these variables was 43.7%.

• Journal of Korea Entertainment Industry Association
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• v.15 no.4
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• pp.299-307
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• 2021

This study is a research study to identify the recognition, experiences, needs of convergence education in occupational therapy students. Therefore, it is intended to provide basic data when developing convergence subjects and non-regular programs within the occupational therapy (department) curriculum. From December 03, 2020, a web questionnaire consisting of 14 questions in 4 areas was distributed over a month, and the data of 130 people were finally analyzed. The results are as follows. First, the recognition and experiences of occupational therapy students in convergence education were low. Second, 57.7% of students recognized that occupational therapy majors need convergence education, and the expected effect of convergence education was 'improvement of occupational therapy job-related knowledge'. Third, it was recognized that 'natural science', 'prosthesis and assistive technology, activity of daily living(ADL)', and 'ADL training' convergence education was necessary for the students of occupational therapy department. The results of this study are expected to be used as basic data in the future development of occupational therapy curriculum and non-regular programs for convergence education. In the future, I think that the demand for convergence education and program development in preparation for the 4th industrial revolution will increase in the occupational therapy curriculum. It is expected that the data of this study will be used meaningfully by professors in charge of occupational therapy education at universities.

• Journal of Nutrition and Health
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• v.55 no.5
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• pp.558-571
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• 2022

Purpose: The purpose of this study was to analyze the dietary intake of Korean adults with atopic dermatitis (AD) to determine whether the risk of developing AD was related to their diet. Methods: Among the participants in the 7th National Health and Nutrition Survey (2016 to 2018), 10,571 adults aged 19-64 were divided into AD (AD group, n = 366) and control groups (non-AD group, n = 10,205) to compare and analyze their nutrient intake status and Korean Healthy Eating Index (KHEI) score. Depending on the prevalence of AD, the nutrient intake, nutrient intake per 1,000 kcal, acceptable macronutrient distribution range, and KHEI score were tested for significance by correcting for age, sex, body mass index, education, marriage, occupation, residence area, physical activity, and energy intake variables that were derived for confounding factors. Results: The acceptable macronutrient distribution range for protein was lower in the AD group than in the non-AD group. Comparing the nutrient intake per 1,000 kcal, the intakes of protein, phosphorus, iron, and potassium of the AD group were significantly lower than those of the non-AD group. In the KHEI, the scores of total vegetables, vegetables excluding kimchi and pickles, meat, fish, eggs, and legumes of the AD group were significantly lower than those of the non-AD group. In addition, as these food intake scores increased, the risk of AD significantly decreased. Conclusion: In conclusion, adult AD patients had low intakes of vegetables, meat, fish, eggs, and legumes, and it was confirmed that high intakes of these foods may be associated with low AD risk. Therefore, we suggest that an adequate intake of vegetables and foods containing protein would be necessary for the management and treatment of AD in adults.

• Journal of Microbiology and Biotechnology
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• v.33 no.5
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• pp.591-599
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• 2023

Fisetin is a bioactive flavonol molecule and has been shown to have antioxidant potential, but its efficacy has not been fully validated. The aim of the present study was to investigate the protective efficacy of fisetin on C2C12 murine myoblastjdusts under hydrogen peroxide (H₂O₂)-induced oxidative damage. The results revealed that fisetin significantly weakened H₂O₂-induced cell viability inhibition and DNA damage while blocking reactive oxygen species (ROS) generation. Fisetin also significantly alleviated cell cycle arrest by H₂O₂ treatment through by reversing the upregulation of p21WAF1/CIP1 expression and the downregulation of cyclin A and B levels. In addition, fisetin significantly blocked apoptosis induced by H₂O₂ through increasing the Bcl-2/Bax ratio and attenuating mitochondrial damage, which was accompanied by inactivation of caspase-3 and suppression of poly(ADP-ribose) polymerase cleavage. Furthermore, fisetin-induced nuclear translocation and phosphorylation of Nrf2 were related to the increased expression and activation of heme oxygenase-1 (HO-1) in H₂O₂-stimulated C2C12 myoblasts. However, the protective efficacy of fisetin on H₂O₂-mediated cytotoxicity, including cell cycle arrest, apoptosis and mitochondrial dysfunction, were greatly offset when HO-1 activity was artificially inhibited. Therefore, our results indicate that fisetin as an Nrf2 activator effectively abrogated oxidative stress-mediated damage in C2C12 myoblasts.