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http://dx.doi.org/10.5010/JPB.2021.48.3.124

Research status of transcription factors involved in controlling gene expression by nitrate signaling in higher plants  

Jung, Yu Jin (Division of Horticultural Biotechnology, Hankyong National University)
Park, Joung Soon (Division of Horticultural Biotechnology, Hankyong National University)
Go, Ji Yun (Division of Horticultural Biotechnology, Hankyong National University)
Lee, Hyo Ju (Division of Horticultural Biotechnology, Hankyong National University)
Kim, Jin Young (Division of Horticultural Biotechnology, Hankyong National University)
Lee, Ye Ji (Division of Horticultural Biotechnology, Hankyong National University)
Nam, Ki Hong (Division of Horticultural Biotechnology, Hankyong National University)
Cho, Yong-Gu (Department of Crop Science, Chungbuk National University)
Kang, Kwon Kyoo (Division of Horticultural Biotechnology, Hankyong National University)
Publication Information
Journal of Plant Biotechnology / v.48, no.3, 2021 , pp. 124-130 More about this Journal
Abstract
Nitrate is an important nutrient and signaling molecule in plants that modulates the expression of many genes and regulates plant growth. In this study, we cover the research status of transcription factors related to the control of gene expression by nitrate signaling in higher plants. Nitrate reductase is a key enzyme in nitrogen assimilation, as it catalyzes the nitrate-to-nitrite reduction process in plants. A variety of factors, including nitrate, light, metabolites, phytohormones, low temperature, and drought, modulate the expression levels of nitrate reductase genes and nitrate reductase activity, which is consistent with the physiological role if. Recently, several transcription factors controlling the expression of nitrate reductase genes have been identified in higher plants. NODULE-INCEPTION-Like Proteins (NLPs) are transcription factors responsible for the nitrate-inducible expression of nitrate reductase genes. Since NLPs also control the nitrate-inducible expression of genes encoding the nitrate transporter, nitrite transporter, and nitrite reductase, the expression levels of nitrate reduction pathway-associated genes are coordinately modulated by NLPs in response to nitrate. Understanding the function of nitrate in plants will be useful to create crops with low nitrogen use.
Keywords
Nitrate; Nitrate signal; NLP transcription factor; Gene expression;
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1 Scheible WR, Morcuende R, Czechowski T, Fritz C, Osuna D, Palacios-Rojas N, Stitt M (2004) Genome-wide reprogramming of primary and secondary metabolism, protein synthesis, cellular growth processes, and the regulatory infrastructure of Arabidopsis in response to nitrogen. Plant physiology 136:2483-2499   DOI
2 Takei K, Sakakibara H, Taniguchi M and Sugiyama, T (2001) Nitrogen-dependent accumulation of cytokinins in root and the translocation to leaf: Implication of cytokinin species that induces gene expression of maize response regulator. Plant and Cell Physiology 42:85-93   DOI
3 Tang PS, Wu HY (1957) Adaptive formation of nitrate reductase in rice seedlings. Nature 179:1355-1356   DOI
4 Wang R, Okamoto M, Xing X, Crawford NM (2003) Microarray analysis of the nitrate response in Arabidopsis roots and shoots reveals over 1,000 rapidly responding genes and new linkages to glucose, trehalose-6-phosphate, iron, and sulfate metabolism. Plant Physiol. 132:556-567   DOI
5 Wu J, Zhang Z, Xia J, Alfatih A, Song Y, Huang Y (2020) Rice NIN-LIKE PROTEIN 4 plays a pivotal role in nitrogen use efficiency. Plant Biotechnol. J pbi.13475
6 Yan D, Easwaran V, Chau V, Okamoto M, Ierullo M, Kimura M, et al. (2016) NIN-like protein 8 is a master regulator of nitrate-promoted seed germination in Arabidopsis. Nat. Commun. 7:13179   DOI
7 Yu LH, Wu J, Tang H, Yuan Y, Wang SM, Wang YP, et al. (2016) Overexpression of Arabidopsis NLP7 improves plant growth under both nitrogen-limiting and -sufficient conditions by enhancing nitrogen and carbon assimilation. Sci. Rep. 6:27795   DOI
8 Zhao L, Liu F, Crawford NM, Wang Y (2018) Molecular regulation of nitrate responses in plants. International journal of molecular sciences 19:2039   DOI
9 Chardin C, Girin T, Roudier F, Meyer C, Krapp A (2014) The plant RWP-RK transcription factors: key regulators of nitrogen responses and of gametophyte development. J. Exp. Bot. 65:5577-5587   DOI
10 Almeida DM, Gregorio GB, Oliveira MM, Saibo NJM (2017) Five novel transcription factors as potential regulators of OsNHX1 gene expression in a salt tolerant rice genotype. Plant Mol. Biol. 93:61-77   DOI
11 Cheng CL, Dewdney J, Kleinhofs A, Goodman HM (1986) Cloning and nitrate induction of nitrate reductase mRNA. Proceedings of the National Academy of Sciences 83:6825-6828   DOI
12 Deng M, Moureaux T, Caboche M (1989) Tungstate, a molybdate analog inactivating nitrate reductase, deregulates the expression of the nitrate reductase structural gene.Plant Physiology 91:304-309   DOI
13 Forde BG (2002) The role of long-distance signalling in plant responses to nitrate and other nutrients. J. Exp. Bot. 53:39-43   DOI
14 Hilhorst HW, Karssen CM (1989) Nitrate reductase independent stimulation of seed germination in Sisymbrium officinale L. (hedge mustard) by light and nitrate. Annals of Botany 63:131-137   DOI
15 Hoff T, Truong HN, Caboche M (1994) The use of mutants and transgenic plants to study nitrate assimilation. Plant. Cell Environ. 17:489-506   DOI
16 Konishi M, Yanagisawa S (2011a) Roles of the transcriptional regulation mediated by the nitrate-responsive cis-element in higher plants. Biochemical and Biophysical Research Communications 411:708-713   DOI
17 LaBrie ST, Wilkinson JQ, Crawford NM (1991) Effect of chlorate treatment on nitrate reductase and nitrite reductase gene expression in Arabidopsis thaliana. Plant physiology 97:873-879   DOI
18 Konishi M, Yanagisawa S (2013b) Arabidopsis NIN-like transcription factors have a central role in nitrate signalling. Nature communications 4:1-9
19 Konishi M, Yanagisawa S (2014) Emergence of a new step towards understanding the molecular mechanisms underlying nitrate-regulated gene expression. J. Exp. Bot. 65:5589-5600   DOI
20 Krouk G, Crawford NM, Coruzzi GM, Tsay YF (2010) Nitrate signaling: adaptation to fluctuating environments. Curr. Opin. Plant Biol. 13:265-272   DOI
21 Schauser L, Roussis A, Stiller J, Stougaard J (1999) A plant regulator controlling development of symbiotic root nodules. Nature, 402:191-195   DOI
22 Tsay YF, Chiu CC, Tsai CB, Ho CH, Hsu PK (2007) Nitrate transporters and peptide transporters. FEBS letters 581:2290-2300   DOI
23 Yu J, Xuan J, Tian Y, Fan L, Sun J, Tang W (2020) Enhanced OsNLP4-OsNiR cascade confers nitrogen use efficiency by promoting tiller number in rice. Plant Biotechnol. J. 19:167-176   DOI
24 Scheible WR, Gonzalez-Fontes A, Lauerer M, Muller-Rober B, Caboche M, Stitt M (1997) Nitrate acts as a signal to induce organic acid metabolism and repress starch metabolism in tobacco. The Plant Cell 9:783-798   DOI
25 Schauser L, Wieloch W, Stougaard J (2005) Evolution of NIN-Like Proteins in Arabidopsis, Rice, and Lotus japonicus. J. Mol. Evol. 60:229-237   DOI
26 Wang R, Xing X, Wang Y, Tran A, Crawford NM (2009) A genetic screen for nitrate regulatory mutants captures the nitrate transporter gene NRT1.1. Plant Physiol. 151:472-478   DOI
27 Castaings L, Camargo A, Pocholle D, Gaudon V, Texier Y, Boutet-Mercey S, Krapp A (2009) The nodule inception-like protein 7 modulates nitrate sensing and metabolism in Arabidopsis. The Plant Journal 57:426-435   DOI
28 Crawford NM (1995) Nitrate: nutrient and signal for plant growth. Plant Cell 7:859-868   DOI
29 Gowri G, Kenis JD, Ingemarsson B, Redinbaugh MG, Campbell WH (1992) Nitrate reductase transcript is expressed in the primary response of maize to environmental nitrate. Plant molecular biology 18:55-64   DOI
30 Landrein B, Formosa-Jordan P, Malivert A, Schuster C, Melnyk CW, Yang W, Jonsson H (2018) Nitrate modulates stem cell dynamics in Arabidopsis shoot meristems through cytokinins. Proceedings of the National Academy of Sciences 115:1382-1387   DOI
31 Liu KH, Niu Y, Konishi M, Wu Y, Du H, Sun Chung H, et al. (2017) Discovery of nitrate-CPK-NLP signalling in central nutrient-growth networks. Nature 545:311-316   DOI
32 Konishi M and Yanagisawa S (2010) Identification of a nitrate-responsive cis-element in the Arabidopsis NIR1 promoter defines the presence of multiple cis-regulatory elements for nitrogen response. The Plant Journal 63:269-282   DOI
33 Konishi M, Yanagisawa S (2013a) An NLP-binding site in the 3'flanking region of the nitrate reductase gene confers nitrate-inducible expression in Arabidopsis thaliana (L.) Heynh. Soil Science and Plant Nutrition 59:612-620   DOI
34 Krapp A, David LC, Chardin C, Girin T, Marmagne A, Leprince AS, et al. (2014) Nitrate transport and signalling in Arabidopsis. J. Exp. Bot. 65:789-798   DOI
35 Maeda SI, Konishi M, Yanagisawa S, Omata T (2014) Nitrite transport activity of a novel HPP family protein conserved in cyanobacteria and chloroplasts. Plant and Cell Physiol 55:1311-1324   DOI
36 Marchive C, Roudier F, Castaings L, Brehaut V, Blondet E, Colot V, et al. (2013) Nuclear retention of the transcription factor NLP7 orchestrates the early response to nitrate in plants. Nat. Commun. 4:1713   DOI
37 Masclaux-Daubresse C, Daniel-Vedele F, Dechorgnat J, Chardon F, Gaufichon L, and Suzuki A (2010) Nitrogen uptake, assimilation and remobilization in plants: challenges for sustainable and productive agriculture Ann Bot. 105:1141-1157   DOI
38 Obertello M, Shrivastava S, Katari MS, Coruzzi GM (2015) Cross-species network analysis uncovers conserved nitrogen-regulated network modules in rice. Plant physiology 168:1830-1843   DOI
39 Konishi M, Yanagisawa S (2011b) The regulatory region controlling the nitrate-responsive expression of a nitrate reductase gene, NIA1, in Arabidopsis. Plant and Cell Physiology 52:824-836   DOI
40 Wang R, Tischner R, Gutierrez RA, Hoffman M, Xing X, Chen M, Crawford NM (2004) Genomic analysis of the nitrate response using a nitrate reductase-null mutant of Arabidopsis. Plant physiology 136:2512-2522   DOI
41 Pouteau S, Cherel I, Vaucheret H, Caboche M (1989) Nitrate reductase mRNA regulation in Nicotiana plumbaginifolia nitrate reductase-deficient mutants. The Plant Cell 1:1111-1120   DOI
42 Redinbaugh MG, Campbell WH (1993) Glutamine synthetase and ferredoxin-dependent glutamate synthase expression in the maize (Zea mays) root primary response to nitrate (evidence for an organ-specific response). Plant physiology 101:1249-1255   DOI
43 Riveras E, Alvarez JM, Vidal EA, Oses C, Vega A, Gutierrez RA (2015) The calcium ion is a second messenger in the nitrate signaling pathway of Arabidopsis. Plant physiology 169:1397-1404   DOI
44 Sakakibara H, Takei K, Sugiyama T (1996) Isolation and characterization of a cDNA that encodes maize uroporphyrinogen III methyltransferase, an enzyme involved in the synthesis of siroheme, which is a prosthetic group of nitrite reductase. The Plant Journal 10:883-892   DOI