• Title/Summary/Keyword: science of prescriptions

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A prescription study in 『Dongeuibogam』 for the Applications of Cnidii Rhizoma (천궁(川芎)의 활용(活用)을 위한 『동의보감(東醫寶鑑)』 처방연구(處方硏究))

  • Jang, A-Ryoeng;Lee, Jin-Ho;Kim, Tae-Hyun;Kim, Dong-Hyun;Choi, Hyung-Wook;Jung, Myung;Yun, Yong-Gab;Lim, Kyu-Sang
    • Herbal Formula Science
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    • v.22 no.1
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    • pp.13-32
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    • 2014
  • Objectives : Until now the study of Cnidii Rhizoma, hemorrhage, brain waves, such as ischemic brain injury, analgesic, effect overcome of the stress from pregnancy melanin formation and inhibiting effects skin whitening have been published regarding this article. Cnidii Rhizoma demonstrates its different abilities depending on the characteristics. This paper reported that effect of Cnidii Rhizoma in Dongeuibogam blended prescriptions as main medicine. In addition, by analyzing data, we studied about utilizing of Cnidii Rhizoma. Methods : Cnidii Rhizoma in Dongeuibogam Prescriptions as the main ingredient was built with database of 202 prescriptions. Thus analyzed data was summarized in detail.(Table-1) If there is no difference in the title of the prescription but in other case the configuration information is different, formulations 1 and 2 were divided by the table. Results : The following results were reached through investigations on the prescriptions usikng Cnidii Rhizoma as a key component. 1. Prescriptions taking Cnidii Rhizoma as a monarch drug are utilized for 40 therapeutic purposes. In particular, 12.3% of prescriptions appear in the chapter of head, and 10.8% of those appear in the chapter of women, and 9.4% of eye, 8.9% of child, 6.4% of wind disease respectively. 2. Prescriptions utilizing Cnidii Rhizoma as the main ingredient are used in the treatment of headache, dizziness and pregnancy hemorrhage fetal movement, premature birth and they are also used for treating 131 different types of disease. 3. The dosage of Cnidii Rhizoma in formulas is from 2pun(about 0.75g) to 5don(nearly 18.75g), however 1don(nearly 3.75g) has been taken the most for clinical application. 4. We find out that according to herbs or prescriptions, Cnidii Rhizoma has a variety of functions such as ascending & descending of energy. Samultang is the most useful base prescription which used the Cnidii Rhizoma as the main component. Conclusion : These results suggest that, Cnidii Rhizoma once-amount use (don nearly 3.75g) 4g in head, gynecology, ophthalmology, pediatrics and paralysis disease associated with oriental medicine resource development can be considered to be widely used These results suggest that Cnidii Rhizoma was used most with 1 don(4g) and can be widely used for the resource development to the disease such as brain, gynecology, ophthalmologhy, pediatrics and wind-associated symptoms.

Translation study on the Gageum's Sanghanbuik (가금(柯琴) "상한부익(傷寒附翼)" 번역(飜譯) 연구(硏究))

  • Jeong, Chang-Hyun;Jang, Woo-Chang
    • Journal of Korean Medical classics
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    • v.18 no.3 s.30
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    • pp.183-206
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    • 2005
  • 'Sanghallonju'(傷寒論注) reorganized the formation according to method of 'the classification of similar symptoms' and annotated the text of Sanghallon, introducing his new methodology and 'Sanghallonik'(傷寒論翼) proclaimed his new finding of the science of the Sanghan. Meanwhile, 'Sanghanbuik' (傷寒附翼) explains various prescriptions in the 'Sanghallon'. It categorizes prescriptions according to the six Meridians and sum up Gageum's research by commenting on the target symtoms and the use of medicine on each prescriptions. Gageum's study is consistent in desire for embodying the universality of the differentiation of syndromes in accordance with the theory of the six Meridians.(六經辨證) in the medical scene. From his work, the substantiality of the six 'Sanghandbuik' is a publication that shows the essence of Gageum's medical science from his inclination, conclusion and concrete methodology.

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Satellite Overquenching Problem

  • Yi, Suk-Young;Kimm, Tay-Sun
    • Bulletin of the Korean Space Science Society
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    • 2009.10a
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    • pp.34.3-34.3
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    • 2009
  • We have investigated the recent star formation history of the nearby galaxies using the SDSS optical and Galex UV data. To everyone's surprise, we found that roughly 30 percent of elliptical galaxies had a residual star formation in the last billion years, suggesting that residual star formation has been common even in ellipticals. Galaxy evolution models based on semi-analytic prescriptions including AGN feedback reasonably reproduce the star formation properties of elliptical galaxies. However, we found that the current galaxy models miserably fail to reproduce the star formation properties of satellite disc galaxies in cluster environments. Satellite disc galaxies in models are overly star-formation quenched in comparison to observation. Detailed investigations led us to conclude that this is due to the use of inaccurate prescriptions for the gas content evolution in the model. I present a solution to the problem by adopting more realistic physical prescriptions.

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The Effects of the ARCS Model for Learners' Achivement and Motivation in Highschool Earth Science (동기유발을 위한 ARCS 이론을 적용한 수업이 지구과학 학업성취도와 태도에 미치는 영향)

  • Park, Soo-Kyong;Kim, Young-Han;Kim, Sang-Dal
    • Journal of The Korean Association For Science Education
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    • v.16 no.4
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    • pp.429-440
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    • 1996
  • This study examined the effects of the ARCS model for science education and found a way of improving ARCS while finding any weaknesses. More specific research questions were as follows: 1) Does the ARCS model enhance the learners' achivement in highschool Earth Science significantly?; 2) Does the ARCS model enhance the learners' motivation in highschool Earth Science significantly?; 3) What are the weaknesses of the prescriptions of the ARCS model for designing a lesson, if any?; 4) How can the weaknesses of the prescriptions of the ARCS modeI be overcome? In order to fulfill the purpose of this study, the two major research methodologies were implemented: pretest-posttest control group design and formarive research. This study was conducted in two distinct phases: 1) designing a set of instructions for 4 weeks with the principles of the ARCS model (to find the weaknesses of the ARCS model) and 2) teaching the instructions and checking the effectiveness of the ARCS model by pretest and posttest with control and experimental groups(to find weaknesses of the underlying theory of the ARCS). After the experiment, each group took an achievement test and an attitude test on the given instruction and gathered data were analyzed with t-tests. Also, from each four classes 7$\sim$8 students were randomly sampled and individually interviewed about the instructional effectiveness and their preference on the instructions. The results of this study are summarized as follows: Significant differences between the control group and experimental group are seen in three components; Attention, relevance, and satisfaction. No significant differences are seen in the attitude of confidence. The weakness of the prescriptions of the ARCS model, are insufficient of strategy for 'confidence'. For overcoming the weaknesses of the prescriptions of the ARCS model, developmental type research is needed.

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Literature Study on Skincare Related Prescription in 『Donguibogam』 : Focused on Functions and Application Methods (『동의보감』 내 미용 처방 선별 연구 : 기능과 용법을 중심으로)

  • Cho, Gayoung;Park, Hyomin;Jung, Wonmo;Chae, Younbyoung;Cha, Woongsuk;Kim, Namil
    • The Journal of Korean Medical History
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    • v.31 no.2
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    • pp.63-72
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    • 2018
  • As Korea's representative medical text, "Donguibogam" reveals Korean Medicine's unique perspective on the human body. The text also contains abundant resources related to skin, leading to diverse researches on the subject today. In this paper, authors tried to elicit values of "Donguibogam" in the general cosmetics field, through literature review. First, prescriptions related to main functions of modern cosmetics (anti-aging, whitening, and moisturizing) were classified. In relation to anti-aging, concepts such as 返老 (reversing aging), 還童 (to become young again), 皺 (wrinkle), and 皮急 (tense skin) were extracted and 69 examples of treatments were introduced. For whitening care, 41 treatments were mentioned on hyper-pigmentation and general complexion. Concepts related to moisturizing included expressions such as 潤肌膚 (hydration of skin) and 光澤 (glow), induced by 48 treatment prescriptions. Second, cosmetics related prescriptions were classified according to the application methods of modern cosmetics. 78 prescriptions of cleansing category included washing-off local area with herbal liquid, bathing, washing-off after steaming, and soaking the body in the herbal liquid. Total of 308 topical application prescriptions covered the conditions of various skin inflammations, scalp illnesses, and etc. In conclusion, this research examines the value of "Donguibogam" as a useful of skincare. Further studies are expected to extend our understanding of the field.

Applications of Prescriptions Including Astragali Radix and Angelicae gigantis Radix in Dongeuibogam (동의보감(東醫寶鑑) 중(中) 황기(黃芪)와 당귀(當歸)가 배오(配伍)된 방제(方劑)의 활용(活用)에 대한 고찰(考察))

  • Kwon, Hyun-Kyong;Kook, Yoon-Bum
    • Herbal Formula Science
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    • v.19 no.1
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    • pp.51-58
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    • 2011
  • Objectives : This study was performed to investigate applications of 171 prescriptions including Astragali Radix and Angelicae gigantis Radix in Dongeuibogam. Methods : 171 prescriptions including Astragali Radix and Angelicae gigantis Radix which have been used separately or concurrently in Oriental Medicine for a long time as a treatment for various disease in Dongeuibogam were studied through order of frequency, symptoms, dosages, etc. Results : 1. 27 times(15.79%) prescriptions are recorded in intumescence chapter, 21 times(12.28%) in fatigue chapter, 11 times(6.43%) in women chapter and 9 times(5.26%) in anus chapter, which are arranged in order of frequency. 2. Yin-yang deficiency treat herbs are ranked top, eliminating intumescence methods, bloody stool, discharging blood from one's vagina, yang deficiency treat herbs are ranked in order of frequency among 107 symptoms in prescriptions including Astragali Radix and Angelicae gigantis Radix. 3. The dosages of Astragali Radix which is more used than Angelicae gigantis Radix are ranged from 3 puns:1 pun ~ 2 nyangs:1.5 nyangs. 1 jeon:5 puns is recorded 8 times(14.29%), 2 jeon:1 jeon is 7 times(12.50%), 1 jeon:3 puns and 1 jeon:7 puns are 24 times(11.2%), 1 nyang is 21 times(9.8%), same amount is 11 times(5.1%), 5 pun is 4 times(7.14%) each, 1.5 jeon:5 puns is 3 times(5.36%) used among 56 prescriptions including Astragali Radix and Angelicae gigantis Radix. 4. The dosages of Astragali Radix which is used same amount Angelicae gigantis Radix are ranged from 2.5 puns each ~ 2 nyangs each, 2.5 chons, same amount each. 1 jeon each is recorded 36 times(38.71%), 1 nyang each is 15 times(16.13%), 0.7 jeon each is recorded 12 times(12.90%), 0.5 jeon each is recorded 6 times(6.45%) used among 93 prescriptions including Astragali Radix and Angelicae gigantis Radix. 5. The dosages of Astragali Radix which is less used than Angelicae gigantis Radix are ranged from 3 puns:7 pun ~ 5 nyangs:12 nyangs. 1 jeon:1.5 jeons is recorded 3 times(13.64%), 0.8 jeon:1 jeon and 1 nyang:2 nyangs are 2 times(9.09%) each, the others are 1 time(4.55%) used among 22 prescriptions including Astragali Radix and Angelicae gigantis Radix. 6. The dosages of (Astragali Radix $\gg$ Angelicae gigantis Radix), (Astragali Radix = Angelicae gigantis Radix) and (Astragali Radix $\ll$ Angelicae gigantis Radix) which are recorded by counts (decoction groups: the other groups) are 52:4(92.86%:7.14%), 70:23(75.27%:24.73%), 13:9 (59.09%:40.91%) respectively. 7. The less using dosage of Astragali Radix and Angelicae gigantis Radix has a more percentage of decoctions groups, The more using dosage of Astragali Radix and Angelicae gigantis Radix has a more percentage of the other groups except decoctions. The less using prescriptions have an effects of controling yin and yang, enhancing blood and chi, etc, as a whole. The more using prescriptions as a form of compound powder have an effects in incurableness disease, chronic diseases, etc. Conclusions : The 171 prescriptions including Astragali Radix and Angelicae gigantis Radix in Dongeuibogam are mainly composed of Dangguibohyul-tang, Samool-tang, Sagoonja-tang and Gobangpoong-tang, Gamri-hwan, etc.

A Study on Application of Pyungwuisan Blended Prescriptions From Dongeuybogam (동의보감(東醫寶鑑) 중(中) 평위산연계방(平胃散連繫方)의 활용(活用)에 대한 고찰(考察))

  • Liu Chin-The;Lee Hak-Jae;Kim Young-Il;Lee Young-Sook;Cho Dae-Yeon;Park Jong-Chan;Yun Yong-Gab
    • Herbal Formula Science
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    • v.12 no.1
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    • pp.1-27
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    • 2004
  • The following are the conclusions obtained by the philological study of the prescriptions introduced in Dongeuybogam such as Pyungwuisan, Pyungwuisan-added prescriptions, Pyungwuisan blended prescriptions: 1. Pyungwuisan and drugs based on Pyungwuisan were prescribed for stomach diseases, food poisoning, indigestion, impaired spleen, symptoms developed by dampness, diseases caused by changing water, diarrhea, edema, malignant malaria, an intestinal convulsion, blood in excrement, malaria, abortion, sparrow eye. 2. Dual prescriptions using Pyungwuisan and other independent prescriptions were applied to internal diseases concerning digestion, diarrhea and dysentery, abscess, intestinal swelling jaundice, symptoms developed by dampness, malaria, vomit, etc. 3. Etiological factors and diseases for which Pyungwuisan and medicines based on Pyungwuisan, dual prescriptions using Pyungwuisan were prescribed, were surveyed to include indigestion, weak spleen and stomach, drying dampness of spleen and stomach, dysfunctioning gall bladder, infection, damaged internals, external sensitiveness and internal damage, hypochondria, chilliness due to lack of chi. 4. A prescription for each disease needed specially added medicines to Pyungwuisan as the following: 1) For indigestion and dyspepsia, Pyungwuisan were prescribed with optional addition of Hoisaengsan, Sagunjatang, Ryukgunjatang, Ijintang, Sosihotang, etc., according to the symptoms, and were most frequently used with aromatic and digestive medicines such as mawwa medivata fermentata, malt, natgrass galingale rhizome, vilous amomum fruit, aucklandia root, round cardamom seed etc. 2) For diseases originated from damage by coldness, Pyungwuisan was taken with suitable amount of Jichulhwan, Hyangsosan, Hyangyusan, according to the symptoms. 3) For diarrhea and dysentery, Pyungwuisan were prescribed with the recipes of Oryeongsan, Sambaektang, Ijintang. 4) For jaundice, prescriptions always included natgrass galingale rhizome in the recipe of Pyungwuisan. 5) For malaria, mostly added prescriptions to Pyungwuisan were Sagunjatang, Ryukgunjatang, Ijintang, with usual addition of antifebrile dichroa root, tsaoko, green tangerine orange peel. 6) Pyungwuisan was prescribed with Hoisaengsan for vomit, with Oryeongsan for edema, and with kinds of Ueolgukhwan for hypochondria.

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Study on the Applications of prescriptions including Platycodi Radix as a main component in Dongeuibogam (동의보감(東醫寶鑑) 중(中) 길경(桔梗)이 주약(主藥)으로 배오(配伍)된 방제(方劑)의 활용(活用)에 대한 고찰(考察))

  • Lee, Tae-Hyung;Lee, Sung-Jun;Huh, Jin;Shin, Dong-Gean;Lee, Jae-Cheol;Shin, Yong-Seo;Yun, Young-Gab
    • Herbal Formula Science
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    • v.18 no.1
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    • pp.23-42
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    • 2010
  • This report describes 90 prescriptions related to the use of Platycodi Radix main blended from Dongeuibogam. The following conclusions were reached through investigations on the prescriptions that use Platycodi Radix as a key component. Prescriptions that Platycodi Radix was taken as a monarch drug are utilized for 30 therapeutic purposes, for example, cough disease, throat disease, abscess and pus, and wind disease. In particular, 12.1% of prescriptions appear in the chapter of cough, and 9.9% of those appear in the chapter of throat, and each 8.8% of those appear in the chapter of abscess and of wind disease. Prescriptions that utilize Platycodi Radix as the main ingredient are used in the treatment of cough disease, throat disease and abscess, and they are also used for treating 74 different types of disease. The prescriptions are compounded with Platycodi Radix as a monarch drug are related to exogenous agents such as wind-cold pathogen, wind-heat pathogen, epidemic diseases, and endogenous agents such as seven emotions, and non-endo-exopathogenic factors like excessive labor, deficiency of Qi and blood, phlegm-mass, phlegm-fire, ect. The dosage of Platycodi Radix is 2pun(about 0.75g) to 1nyang(about 37.5g), however 1don (about 3.75g) has been taken the most for clinical application. We can find out that according to herbs or prescriptions blended with it self, Platycodi Radix makes a variety of functions to penetrate lung stagnancy and remove phlegm, relieve throat pain and get rid of pus, and regulate Qi flow. And Gamgiltang is the most useful base prescription which used the Platycodi Radix as the main component.

Network Analysis of Prescriptions for Inflammatory Bowel Disease - Preliminary Exploration of Prescriptions Using the K-HERB Database - (염증성 장질환 처방에 대한 네트워크 분석 - K-HERB 데이터베이스를 활용한 예비적 처방 탐색 -)

  • Jae-Yeon Lee;Yu-Gyeong Lee;Yeon-Hwa Lee;Seojung Ha;Bo-In Kwon
    • Journal of Society of Preventive Korean Medicine
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    • v.28 no.2
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    • pp.131-150
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    • 2024
  • Objectives : The aim of this study was to perform network analysis and analysis using the K-HERB database on inflammatory bowel disease (IBD), to verify the similarity between the derived networks and existing prescriptions, and to explore the possibility of developing new IBD prescriptions preliminarily. Methods : We conducted a comprehensive literature search on July 6, 2024, utilizing databases such as ScienceON, RISS, and OASIS. Clinical studies assessing the efficacy of herbal medicine in treating Crohn's disease and ulcerative colitis were identified and compiled into a structured database. This dataset, which included related prescriptions and herbal formulations, was subsequently analyzed using NetMiner 4 for centrality and Louvain clustering analyses. We then compared the networks derived from the K-HERB database with existing therapeutic prescriptions to assess their similarity. Results : A total of 24 prescriptions and 66 herbs were identified across the surveyed studies on IBD. Paeoniae Radix Alba(白芍藥) emerged as the most frequently utilized herb for both Crohn's disease and ulcerative colitis. Prominent herb combinations included Paeoniae Radix Alba-Angelicae Sinensis Radix (白芍藥-當歸), Angelicae Sinensis Radix-Coptidis Rhizoma (當歸-黃連), and Coptidis Rhizoma-Scutellariae Radix (黃連-黃芩) for ulcerative colitis. Centrality analysis revealed that Poria cocos (茯苓) and Paeoniae Radix Alba (白芍藥) had high centrality in the Crohn's disease, while Angelicae Sinensis Radix (當歸) and Paeoniae Radix Alba (白芍藥) had high centrality in the ulcerative colitis, indicating their prominent roles within the networks. Cohesion analysis resulted in 7 networks for Crohn's disease and 16 networks for ulcerative colitis. After excluding networks with a single herb, three networks related to Crohn's disease and two related to ulcerative colitis were examined using the K-HERB database. Among the 14 derived prescriptions for Crohn's disease and seven for ulcerative colitis, all except Oryeong-san (五苓散) were non-traditional in the context of IBD treatment. Conclusion : This preliminary study may provide a basis for the understanding and application of herbal prescriptions for IBD based on network analysis and the K-HERB database.

Pathologic Study on Representative Prescriptions in 『Wenbingtiaobian』 and their Coverage of Diseases (『온병조변(溫病條辨)』 대표 처방의 병리학적 분석과 질환 범위 고찰)

  • Park, Mi Sun;Kim, Yeong Mok
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.32 no.1
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    • pp.1-12
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    • 2018
  • This article is for understanding characteristics of febrile disease through analysing usage of representative prescriptions in "Wenbingtiaobian", composition of their related prescriptions and their coverage of modern diseases. Analysis of prescriptions was based on "Translation of Wenbingtiaobian", "Modern Shanhanlun" and "Herbal Formula Science" and clinical papers were searched in China Academic Journals(CAJ) of China National Knowledge Infrastructure(CNKI). Conclusions are as follows. First, principles of modifying or formulating prescriptions for febrile diseases are clearing heat, nourishing yin or dispelling dampness. Second, Zengyechengqitang, Xinjiahuanglongtang and Huweichengqitang are applied to pattern of bowel excess such as constipation or ileus. Third, Jiajianfumaitang is applied to heart diseases, Sanjiafumaitang to liver and heart, Dadingfengzhu to liver diseases. Fourth, Jiajianzhengqisan related prescriptions are applied to spleen diseases like conspitation, diarrhea or gastritis. Fifth, Baihujiarenshentang is applied to diabetes or fever and Baihujiaguizhitang to gout or arthritis. Sixth, Xuanbaichengqitang is applied to lung diseases and Taorenchengqitang to gynecology diseases. Seventh, Sanrentang is applied lung diseases like cough or pneumonia, spleen diseases like diarrhea or enteritis and kidney diseases like edema, arthritis or leucorrhea. Eighth, Yinqiaosan and Sangjuyin tend to be applied to exogenous diseases and diseases of five organs of sense, Jiajianfumaitang and Sanjiafumaitang to heart diseases, Angongniuhuangwan to encephalopathy, Qingyingtang and Huabantang to skin diseases, Zengyetang to gastrointestinal disorders, Shashenmaidongtang to lung or spleen diseases.