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NECROSIS OF A PAROTID GLAND PLEOMORPHIC ADENOMA : A CASE REPORT (이하선 다형성 선종의 괴사)

  • Ryu, Sun-Youl;Baek, Sung;Park, Hong-Ju;Choi, Hong-Ran
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.30 no.2
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    • pp.165-169
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    • 2004
  • Pleomorphic adenoma is the most common neoplasm of the parotid gland, generally presenting as a slowly growing, firm, well-circumscribed, painless nodule. It is often difficult to separate into benign and malignant categories because its bland histomorphologic and cytologic features. This tumor can be rarely associated with cystic change, hemorrhagic necrosis, or spontaneous infarction. Necrosis of lesional tissue may be associated with malignant transformation, particularly in a pleomorphic adenoma. We report a case of 50-year-old woman presented with a enlarging right parotid mass. Computed tomographic scan demonstrated a right superficial lobe mass with ill-defined border. The preoperative fine needle aspiration yielded necrotic debris and atypical squamous elements that were thought to be compatible with high degree of mucoepidermoid carcinoma. A total parotidectomy with intraoperative frozen section revealed extensive necrosis and diagnosed as malignant tumor. This tumor was finally diagnosed as a pleomorphic adenoma with necrosis on permanent sections. Caution should be exercised in evaluation of the parotid neoplasms with central necrosis to avoid misdiagnosis of such lesions as malignancy.

Development of Elderly Meaning in Life (EMIL) Scale (노인의 생의 의미 측정 도구 개발)

  • 최순옥;김숙남;신경일;이정지;정유진
    • Journal of Korean Academy of Nursing
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    • v.33 no.3
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    • pp.414-424
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    • 2003
  • Purpose: The purpose of this study was to develop elderly meaning in life scale with high validity and reliability. Method: The process of development of this scale were as follows. A conceptual framework composed of 4 phases of meaning in life of elderly was identified based on the literature review and interviews with elderlies and discussion with experts in meaning in life. Total 62 items, 4-points scale were developed. Through reliability testing, factor analysis, 40 preliminary items were selected. By means of internal consistency of 40 items, 2 items whose inner-items correlation coefficient was below .30 were deleted. Through factor analysis 1 item whose factor loading was below .30 was deleted. Finally 37 items were remained. To verify 37 items, factor analysis, reliability testing, LISEREL were done. Data were collected from 320 elderly subjects in Busan-KyungNam and Jeonla Province from May to June in 2002. SPSS WIN. 10.0 Program was used. Result: The result of factor analysis of 37 items, 8 factors were extracted. These factors were labeled as ‘self- awareness and self-acceptance’, ‘contentedness with life’, ‘purpose in life’, ‘love in family’, ‘role awareness’, ‘futuristic aspiration’, ‘commitment’, and ‘experience of love’. These factors included 4 phases of the meaning in life. Cronbach's Alpha of 37 items was .908 and correlation coefficient of PIL was .75. Conclusion: The researchers recommend the follows: The explorative study on the variables related to meaning in life are needed for criterion validity of this scale. The studies on meaning in life of different age groups, subjects are needed for reverification.

Nurses′ Image Perceived by Academic and Vocational High School Teachers in Korea (고등학교 교사가 지각한 간호사 이미지)

  • 강혜영;고미혜;양진주;김선민
    • Journal of Korean Academy of Nursing
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    • v.33 no.6
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    • pp.792-801
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    • 2003
  • Purpose: The purpose of this study was to identify nurses' image and its related factors to make nurses' image among academic and vocational high school teachers in Korea. Method: Study samples were composed of 470 teachers who were from 12 high schools in G and J city located in southwestern part of Korea. Data were collected from August 26 to October 4, 2002. The internal consistency of the total scale was Cronbach's $\alpha$=.940. Result: In order to make nurses' image, 76.4% of respondents were influenced by the experience of their hospitalization in visiting hospitals. The mean score of nurses' image in general was 3.19$\pm$0.55; in four subcategories, 3.46$\pm$0.60 for professional image, 3.28$\pm$0.69 for traditional image, 2.93$\pm$0.70 for social image, and 2.91$\pm$0.64 for vision of nursing career. The mean score of nurses' image in general was more positive significantly in the 50's age group (F=6.43, p=.002) and in male groups (t=2.92, p=.002). Conclusion: On the basis of these findings, nursing professionals need to improve their working conditions, aspiration in job, and autonomy of nurses in their practice fields, monitor the mass media and other publishing materials continuously, and share the appropriate information on nursing profession to the school teachers and the public.

Metastatic lipid-rich mammary carcinoma in a dog

  • Kim, Myung-Chul;Kim, So-Yeon;Lee, Su-Hyung;Kim, Dae-Yong;Yoon, Jung-Hee;Kim, Wan Hee;Lee, Jeong-Ha;Kim, Yongbaek
    • Korean Journal of Veterinary Research
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    • v.54 no.4
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    • pp.265-268
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    • 2014
  • An adult female dog was presented for evaluation of mammary gland masses. Complete blood count and serum chemistry data were within normal limits. Fine-needle aspiration cytology of the mammary masses revealed clusters of malignant epithelial cells with clear cytoplasmic vacuoles. Based on histopathological findings, a diagnosis of lipid-rich mammary carcinoma was made. Approximately 5 weeks after surgical removal, the tumor recurred at the surgery site and metastasis to the tibia was detected. Due to the poor prognosis and deterioration of the condition, the dog was euthanized.

Sialadenitis caused by iatrogenic trauma: A case report (의원성 사고로 발생한 타액선염:증례보고)

  • Kim Hyun-Woo;Huh Kyung-Hoe;Lee Win-Jin;Heo Min-Suk;Lee Sam-Sun;Choi Soon-Chul
    • Imaging Science in Dentistry
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    • v.34 no.2
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    • pp.107-110
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    • 2004
  • A case of sialadenitis is presented in a patient with painful swelling of the right mouth floor. The condition was caused by trauma on the right mouth floor during dental treatment, which had happened 15 days before admission. On aspiration, mucous secretion was found and ultrasonography showed obstruction of duct. Histopathological studies and surgical investigation established a definite diagnosis of obstructive sialadenitis caused by ductal laceration. As surgical treatment sialodochoplasty was selected. The case and relevant considerations are discussed.

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Induction of twinning in Korean native cattle by transfer of nuclear transplanted embryos II. Nuclear transfer using donor embryos originated from ovum pick-up(OPU) and activated recipient cytoplasts (핵이식 기법을 이용한 한우 쌍태생산에 관한 연구 II. Ovum pick-uo(OPU) 유래 공여핵 및 활성화 유도 수핵난자의 핵이식)

  • Hwang, Woo-suk;Shin, Tae-young;Roh, Sang-ho;Park, Jong-im;Lee, Byeong-chun
    • Korean Journal of Veterinary Research
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    • v.38 no.3
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    • pp.652-658
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    • 1998
  • The efficiency of nuclear transfer using donor embryos originated from ovum pickup(OPU) and activated recipient cytoplasts were examined for induction of twinning in Korean native cattle(KNC). After aspiration of follicle by OPU, regardless of the vacuum applied, we obtained same result in proportions of recovered cumulus-oocyte complex (COCs) with compact cumulus. Under electric stimulation(1.0kV/cm DC for $40{\mu}s$), most of activated oocytes proceed to anaphase II/telophase II within 3h(84.7%). In the treatment of oocyte activation, the preactivation which was performed before fusion had significant effect on the developmental rates to morula/blastocyst stage(9.4 vs 4.0%). In embryo transfer of nuclear transferred embryos, we obtained 2 twins from KNC recipients and 1 twin from a Holstein recipient. Our results showed that it is possible to obtain twins using nuclear transfer technique in KNC.

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Alimentary Lymphoma in a ferret (페렛에 발생한 소화기 림프종 1례)

  • Seo, Kyoung-won;Lee, Jong-bok;Jee, Hyang;Lee, So-ra;Kwon, Tae-uk;Kim, Dae-yong;Youn, Hwa-young;Lee, Chang-woo
    • Korean Journal of Veterinary Research
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    • v.47 no.4
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    • pp.479-482
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    • 2007
  • A 2-year-old spayed female ferret with the clinical signs of diarrhea and anorexia for about 8 days was presented to Hansung animal hospital. The diarrhea was black and paste form. Three palpable abdominal masses were detected in physical examination. By cytologic examination using fine need aspiration, the patient was tentatively diagnosed as lymphoma. Chemotherapy was started with prednisone, vincristine and cyclophosphamide. However, the client requested stopping the therapy at day 18 and the ferret was euthanized. Autopsy was performed and the masses were confirmed as lymphoma by histopathology. Microscopically, the mass consisted of unencapsulated and infiltrative neoplasm consisted of closely packed monomorphic round cells and also ininvasive lesions observed in duodenum. On the higher magnification, pleomorphic neoplastic cells with distinct cell border and abundant eosinophilic cytoplasm were observed. Finally, the ferret diagnosed as alimentary lymphoma.

HUGE PLEOMORPHIC ADENOMA OF THE PAROTID GLAND: REPORT OF A CASE (이하선에 발생한 거대 다형성 선종)

  • Ryu, Sun-Youl;Ryu, Seung-Hee;Kim, Tae-Hee
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.28 no.3
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    • pp.247-253
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    • 2006
  • Pleomorphic adenoma of the parotid gland typically presents as painless, mobile mass of long duration, and originate in the superficial lobe but, more rarely these tumors may involve the deep lobe of the parotid gland. The average size of a parotid neoplasm is 2 to 4 cm. The effective treatment of parotid pleomorphic adenoma is surgical excision. The simple excision or enucleation resulted in recurrence rate of 45% in benign tumor. Therefore, the superficial parotidectomy with identification and preservation of the facial nerve is now the most widely accepted surgery. We report a case of the huge pleomorphic adenoma of the left parotid gland in a 67-year-old man who complained the large mass, measured about $10\times7\times5$cm-sized, in front of the left ear and on the mandibular ascending ramus. The diagnosis was confirmed by the clinical examination, computed tomographic scan, fine needle aspiration, and incisional biopsy. Superficial parotidectomy including the tumor and preservation of the facial nerve using the modified Blair approach was performed. And satisfactory results have been obtained cosmetically and functionally.

A Design of KP AGENT for Intelligent Information Retrieval (지능형 정보검색을 위한 KP AGENT의 설계)

  • 박경우;배상현
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.4 no.2
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    • pp.443-451
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    • 2000
  • Until now, there have been various kinds of science information databsae which databased the science technology information, but they do not satisfy the aspiration of the users. Therefore, in the position of the users, it suggests the technology information space as a now paradigm, which supplement the function of science information DB. ICPIS which inputs described papers with keywords, offers the itemized summary of these contents, the visual indication and comparison of similar thesis, and it also supplises the abundant summary information, survey information, more than ten volumes of info communication thesis with starting the casual relation extraction for the users, playing a significant role in ICPIS is called KP, and it is package of domain knowledge that unifies the extraction and structure narration of the technology information. ICPIS extracts the technology information among the thesis that are deserved by the natural language treatment in the itemized KP keywords described, and form the prescribed summary structure in KP.

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Application of Immunophenotyping and Heteroduplex Polymerase Chain Reaction (hPARR) for Diagnosis of Canine Lymphomas

  • Sirivisoot, Sirintra;Techangamsuwan, Somporn;Tangkawattana, Sirikachorn;Rungsipipat, Anudep
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.6
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    • pp.2909-2916
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    • 2016
  • Background: Canine malignant lymphoma is classified into B- or T-cell origin, as in the human case. Due to differences in prognosis, a suitable method needs to be developed for lineage identification. Aims: To determine the accuracy of immunophenotypic and molecular information between three methods: immunocytochemistry (ICC), immunohistochemistry (IHC) and heteroduplex polymerase chain reaction for antigen receptor rearrangements (hPARR) in spontaneous canine lymphomas. Materials and Methods: Peripheral blood, fine needle aspiration and tissue biopsies from enlarged peripheral lymph nodes prior to treatment of 28 multicentric lymphoma patients were collected. Cytopathology and histopathology were examined and classified using the updated Kiel and WHO classifications, respectively. Anti-Pax5 and anti-CD3 antibodies as B- and T-cell markers were applied for immunophenotyping by ICC and IHC. Neoplastic lymphocytes from lymph node and white blood cell pellets from peripheral blood were evaluated by hPARR. Results: In this study, low grade B-cell lymphoma accounted for 25% (7/28), high grade B-cell lymphoma for 64.3% (18/28) and high grade T-cell lymphoma for 10.7% (3/28). According to the WHO classification, 50% of all cases were classified as diffuse large B-cell lymphoma. In addition, ICC showed concordant results with IHC; all B-cell lymphomas showed Pax5+/CD3, and all T-cell lymphomas exhibited Pax5-/CD3+. In contrast to hPARR, 12 B-cell lymphomas featured the IgH gene; seven presented the $TCR{\gamma}$ gene; five cases showed both IgH and $TCR{\gamma}$ genes, and one case were indeterminate. Three T-cell lymphomas showed the $TCR{\gamma}$ gene. The percentage agreement between hPARR and ICC/IHC was 60%. Conclusions: Immunophenotyping should not rely on a single method. ICC or IHC with hPARR should be used concurrently for immunophenotypic diagnosis in canine lymphomas.