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BDNF Promotes Neurite Growth and Survival of Antennal Lobe Neurons from the Silk Moth Bombyx mori in vitro

  • Kim, Jin-Hee;Sung, Dong-Kyung;Park, Chan-Woo;Kim, Kang-Min;Park, Hun-Hee;Kim, Hak-Ryul;Lee, Bong-Hee
    • Proceedings of the Korean Society of Sericultural Science Conference
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    • 2003.10a
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    • pp.99-99
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    • 2003
  • Brain-derived neurotrophic factor (BDNF) induced a significant neurite extension of antennal lobe (AL) neurons from the silk moth Bombyx mori in culture on lamini/ concanavalin A-coated dishes, in comparison with smaller effect of 20-hydroxyecdy-sone (20-HE). But the effect fur neurite extension by 5-hydroxytryptamine (5-HT) could not be found. A significant increase in the number of new primary branches from the principal neurites of AL neurons was also shown in culture with BDNF and 5-HT, but not with 20-HE. (omitted)

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