• Title/Summary/Keyword: scale-up factors

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Radiologic Findings and Risk Factors of Adjacent Segment Degeneration after Anterior Cervical Discectomy and Fusion : A Retrospective Matched Cohort Study with 3-Year Follow-Up Using MRI

  • Ahn, Sang-Soak;So, Wan-Soo;Ku, Min-Geun;Kim, Sang-Hyeon;Kim, Dong-Won;Lee, Byung-Hun
    • Journal of Korean Neurosurgical Society
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    • v.59 no.2
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    • pp.129-136
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    • 2016
  • Objective : The purpose of this study was to figure out the radiologic findings and risk factors related to adjacent segment degeneration (ASD) after anterior cervical discectomy and fusion (ACDF) using 3-year follow-up radiography, computed tomography (CT), and magnetic resonance image (MRI). Methods : A retrospective matched comparative study was performed for 64 patients who underwent single-level ACDF with a cage and plate. Radiologic parameters, including upper segment range of motion (USROM), lower segment range of motion (LSROM), upper segment disc height (UDH), and lower segment disc height (LDH), clinical outcomes assessed with neck and arm visual analogue scale (VAS), and risk factors were analyzed. Results : Patients were categorized into the ASD (32 patients) and non-ASD (32 patients) group. The decrease of UDH was significantly greater in the ASD group at each follow-up visit. At 36 months postoperatively, the difference for USROM value from the preoperative one significantly increased in the ASD group than non-ASD group. Preoperative other segment degeneration was significantly associated with the increased incidence of ASD at 36 months. However, pain intensity for the neck and arm was not significantly different between groups at any post-operative follow-up visit. Conclusion : The main factor affecting ASD is preoperative other segment degeneration out of the adjacent segment. In addition, patients over the age of 50 are at higher risk of developing ASD. Although there was definite radiologic degeneration in the ASD group, no significant difference was observed between the ASD and non-ASD groups in terms of the incidence of symptomatic disease.

Results in Operative Treatment of Open Calcaneal Fracture (개방성 종골 골절의 수술적 치료 결과)

  • Kim, Ba Rom;Lee, Jun Young;Cha, Donghyuk
    • Journal of Korean Foot and Ankle Society
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    • v.25 no.3
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    • pp.133-140
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    • 2021
  • Purpose: This paper reports the surgical treatment results of open calcaneal fractures performed at the author's clinics focusing on open calcaneal fractures to help understand the appropriate treatment and realistic outcomes. Materials and Methods: This study was conducted on 22 cases out of 30 patients who visited the hospital from February 2009 to December 2019 and were followed up for more than one year. In open fractures, the fracture was classified using the Gustilo-Anderson classification and was evaluated using the soft tissue status at the time of visit. Intra-articular calcaneal fractures were classified using Sanders classification. The radiological parameters were measured for the Böhler angle, Gissane angle, calcaneal length, height, and width before and after surgery, and at the last follow-up. The clinical outcomes were evaluated using the American Orthopaedic Foot and Ankle Society (AOFAS) ankle-hindfoot scale and investigated complications. In addition, statistical analysis of the incidence and associated factors of posttraumatic arthritis was conducted. Results: In all cases, the surgical treatment was performed by minimally invasive surgery. The AOFAS ankle-hindfoot scale conducted for a clinical evaluation of the final follow-up was averaged 72.5 points. In the classification of open fractures, the Gustilo-Anderson classification type IIIA was the most common, and the Sanders type III was the most common. Of the 22 cases after surgery, 15 cases had complications, 11 cases had posttraumatic arthritis, eight cases had an infection, and 4 cases had both complications. Only the Sanders classification showed a statistically significant correlation with the incidence of posttraumatic osteoarthritis (p-value 0.032). Conclusion: In treating open calcaneal fractures, internal fixation by a minimally invasive approach showed relatively satisfactory results. However, follow-up research will be needed, including the results of a long-term follow-up through a large number of cases and comparative studies with other surgical methods.

Barix Thin Film Encapsulation of OLED's on Flexible and Rigid Glass substrates; high temperature performance and manufacturing aspects.

  • Chu, X.;Moro, L.;Rutherford, N.;Visser, R.J.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08b
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    • pp.1699-1702
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    • 2007
  • We will discuss encapsulation of OLEDs on both flexible and rigid glass substrates. Accelerated testing at 6CC/90RH and 85C/85RH is compared and acceleration factors for OLED and Calcium test samples are discussed.We have tested the stability and performance of our barrier coating to much higher temperatures: up to 140 C. Water Vapor Transmission rates at temperatures from 60 to 140 C are presented. Rates and methods for low cost manufacturing on a large scale are analysed

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Towards Super Thin OLED TVs: Barix Thin Film Encapsulation of Glass and Flexible Displays

  • Xi, Chu;Lin, Steven;Rosenblum, Marty;Visser, R.J.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2008.10a
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    • pp.1634-1637
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    • 2008
  • We will discuss encapsulation of OLEDs on both flexible and rigid glass substrates. Accelerated testing at 6CC/90RH and 85C/85RH is compared and acceleration factors for OLED and Calcium test samples are discussed.We have tested the stability and performance of our barrier coating to much higher temperatures: up to 140 C. Water Vapor Transmission rates at temperatures from 60 to 140 C are presented. Rates and methods for low cost manufacturing on a large scale are analysed.

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Necessity and adequacy of near-source factors for seismically isolated buildings

  • Saifullah, Muhammad Khalid;Alhan, Cenk
    • Earthquakes and Structures
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    • v.12 no.1
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    • pp.91-108
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    • 2017
  • Superstructures and isolation systems of seismically isolated buildings located close to active faults may observe increased seismic demands resulting from long-period and high-amplitude velocity and displacement pulses existent in near-fault ground motions as their fundamental periods may be close to or coincident with these near-fault pulse periods. In order to take these effects into account, the 1997 Uniform Building Code (UBC97) has specified near-source factors that scale up the design spectrum depending on the closest distance to the fault, the soil type at the site, and the properties of the seismic source. Although UBC97 has been superseded by the 2015 International Building Code in the U.S.A., UBC97 near-source factors are still frequently referred in the design of seismically isolated buildings around the world. Therefore it is deemed necessary and thus set as the aim of this study to assess the necessity and the adequacy of near-source factors for seismically isolated buildings. Benchmark buildings of different heights with isolation systems of different properties are used in comparing seismic responses obtained via time history analyses using a large number of historical earthquakes with those obtained from spectral analyses using the amplified spectrums established through UBC97 near-source factors. Results show that near-source factors are necessary but inadequate for superstructure responses and somewhat unconservative for base displacement response.

Modelling of a Spatial Distribution of the Species Richness of Fishes, Plants, and Birds Using Environmental Factors on a Wide-Ranging Scale1 - Focusing on the Major Drainage Systems in Japan - (광역스케일의 환경 인자를 이용한 어류, 식물, 조류 종수의 공간적 분포에 대한 모델링 - 일본의 주요수계를 중심으로 -)

  • Han, Mi-Deok;Lee, Gi-Bae
    • Korean Journal of Environment and Ecology
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    • v.22 no.4
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    • pp.347-355
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    • 2008
  • This study analyzed and modeled the relationships between the species richness of fish, plant, and bird and environmental factors such as climatic and geographical variables based on data collected from 109 major drainage systems in Japan from 1990 until 2005. As a result, the most parts of the distributions of the fish, plant, and bird species richness were clarified by the average annual atmospheric temperature, dimension of drainage areas, and annual rainfall, respectively. In addition, this study predicted the value of each organism species distributed in national drainage areas in Japan using GAMs(Generalized Additive Models) for each organism model created by environmental factors on a wide-ranging scale, and also mapped out the value. Mapping out the predicted value could make it easier for its managers to newly set up the areas needing to be protected to obtain diversity of the organism species and to assess their availability of conservation for bio-diversity.

Methed for the Passaging of Microcarrier Cultures to a Production Scale for Producing High Titre Disabled Infectious Single Cycle-Herpes Simplex virus Type-2

  • Zecchini, Tracey-Ann;Wright, Paul-Andrew;Smith, Rodney-John
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.5 no.2
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    • pp.118-122
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    • 2000
  • A comlementary call line CR2 is curretly used to propagte the Disabled Infectious Single Cycle Herpes Simplex Virus Typee2 (DISC HSV-2) on a small Iaboratory scale upto 15 L. These cultures are initiated by passaging the cells from roller bottle cultures. Whilst this is suitable for the laboratory scale it is totally impractical for use in seeding an industrial manufacturing scaled version of the culture. It is paramount to have a robust system for passaging cells from a small microcarrierier culture system to a larger one by a serial subculturing regime. Here we report on the successes we have had in our laboratory in scaling up out production system for the DISC HSV-2 from small 1-L cultures to a 50-L vessel with the maintenance of the viral productivity. Ease of use, reproducibility and the need to minimise overall production time were factors which were taken into consideration whils developing our procedures. We were aware of the need to keep a production train simple and as short as possible as this was the amall scale study for an envisaged manufacturing process.

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A Study on the Efficiency of Fishing-Ports Based on Super-SBM (Super-SBM을 이용한 어항의 효율성분석에 관한 연구)

  • Park, Cheol-Hyung
    • The Journal of Fisheries Business Administration
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    • v.41 no.3
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    • pp.129-151
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    • 2010
  • This study is to analyze the efficiency of Korean fishing ports using DEA. First, the study calculated the efficiency scores based on a CCR-BCC framework and hence technical, pure technical, and scale efficiency scores are seperated for the 38 fishing ports under study. The Average of technical, pure technical, and scale efficiency are turned out to be 0.6834, 0.8582, and 0.7774 respectively. The 15 fishing ports are fully efficient under the constant returns to scale while 21 fishing ports under the variable returns to scale. Second, the super efficiency scores are also calculated under the radial model without the consideration of slacks. The highest score is turned out to be 4.4984 for the P16 fishing port with the average score of 0.9652 for the entire fishing ports. Nevertheless, P16 fishing port has showed up only once as a reference set. On the other hand, P34 fishing port has showed up 11 times as a reference set, which scored the second highest score of 2.9815. Finally the super efficiency scores are calculated under the non-radial model with the explicit consideration of slacks. Now the P34 fishing port scored the highest score of 2.3424 with even 15 times referred to a bench-mark. Therefore the importance of P34 fishing port is emphasized once again on the field of bench-marking for the efficiency of fishing ports. When the targets for the input factors to improve the efficiency of each DMU are calculated the area of fishing port needs the most adjustment to be reduced for 40.36% on the average, while the cosignment sales area does the least adjustment for 13.70%.

Correlation Between Balance, Walking Test and Functional Performance in Stroke Patients: BBS, TUG, Fugl-Meyer, MAS-G, C·MGS, and MBI (뇌졸중 환자의 균형과 기능 수행 및 보행 검사를 위한 평가도구의 비교: BBS, TUG, TUG, Fugl-Meyer, MAS-G, C·MGS, and MBI)

  • An, Seung-Heon;Park, Chang-Sik;Lee, Hyun-Ju
    • Physical Therapy Korea
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    • v.14 no.3
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    • pp.64-71
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    • 2007
  • The purposes of this study were to determine correlations between the Berg Balance Test (BBS), Timed -UP & Go Test, Fugl Meyer-L/E, Balance, Sensory (FM-L/E, B, S), Motor Assessment Scale-Gait (MAS-G), Comfortable maximal Gait Speed (C MGS), and the Modified Barthel Index (MBI). The subjects were 40 stroke patients of the Korea National Rehabilitation Center in Seoul. Main outcome measures were Balance control (BBS, FM-B), Gait (TUG, C MGS, MAS-G), ADL (MBI) and Motor Function of Lower Extremities (FM-L/E, S). The data were analyzed using Pearson product correlation. FM scales between other clinical and instrumental indexes and multiple stepwise regression analyses were performed to identify prognostic factors for Balance, Gait and ADL Motor Function of Lower Extremity inclinations. The results of this study were as follows: The BBS, FM-L/E, balance, sensory and MBI showed positive correlation relations, but TUG and C MGS showed negative correlations. The sensory factor of the FM-scale showed the strongest variance in predicting BBS. However the FM-balance showed the strongest variance in predicting TUG, MAS-G and C MGS. The use of both quantitative and qualitative scales was shown to be a good measuring instrument for the classification of the general clinical performance of the patients.

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Correlation Between BBS, FRT, STI, TUG, MBI, and Falling in Stroke Patients (뇌졸중 환자에서 BBS, STI, MBI, TUG, FRT, 낙상과의 상관관계)

  • Lee, Han-Suk;Choi, Jin-Ho
    • The Journal of Korean Physical Therapy
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    • v.20 no.4
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    • pp.1-6
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    • 2008
  • Purpose: We studied the correlation between BBS (Berg Balance Scale), Functional Reach Test (FRT), Timed-Up & Go test (TUG), Stability Index (STI), MBI (Modified Barthel Index), and Fall History. Methods: We recruited 20 stroke patients from the Gang Dong Gu Health Care Center in Seoul, Korea. All subjects could walk with or without an assisting device. Subjects first completed a questionnaire pertaining to their fall history and Activity of Daily Living (MBI), and then were evaluated with BBS, TUG, FRT, and STI. We used the Tetrax posturography system that calculates a STI based on fluctuations in vertical ground reaction forces. The data were analyzed using a Pearson Correlation Coefficient. Results: The BBS and FRT (p<0.05) and MBI (p<0.01) showed a significant positive correlation. BBS negatively correlated with STI and TUG (p<0.01). Fall history and BBS, TUG, MBI, FR, STI did not correlate. Conclusion: The BBS helps predict weight shifting, walking, and ADL, but is not good for predicting fall risk. So, we need to study about factors that affect falling.

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