• Biotechnology and Bioprocess Engineering:BBE
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• 제10권5호
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• pp.425-431
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• 2005

The systems-level analysis of microbes with myriad of heterologous data generated by omics technologies has been applied to improve our understanding of cellular function and physiology and consequently to enhance production of various bioproducts. At the heart of this revolution resides in silico genome-scale metabolic model, In order to fully exploit the power of genome-scale model, a systematic approach employing user-friendly software is required. Metabolic flux analysis of genome-scale metabolic network is becoming widely employed to quantify the flux distribution and validate model-driven hypotheses. Here we describe the development of an upgraded MetaFluxNet which allows (1) construction of metabolic models connected to metabolic databases, (2) calculation of fluxes by metabolic flux analysis, (3) comparative flux analysis with flux-profile visualization, (4) the use of metabolic flux analysis markup language to enable models to be exchanged efficiently, and (5) the exporting of data from constraints-based flux analysis into various formats. MetaFluxNet also allows cellular physiology to be predicted and strategies for strain improvement to be developed from genome-based information on flux distributions. This integrated software environment promises to enhance our understanding on metabolic network at a whole organism level and to establish novel strategies for improving the properties of organisms for various biotechnological applications.

• Wind and Structures
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• 제25권3호
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• pp.233-259
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• 2017

Investigations on simulated near-surface atmospheric boundary layer (ABL) in an open-jet facility are carried out by conducting experimental tests on small-scale models of low-rise buildings. The objectives of the current study are: (1) to determine the optimal location of test buildings from the exit of the open-jet facility, and (2) to investigate the scale effect on the aerodynamic pressure characteristics. Based on the results, the newly built open-jet facility is well capable of producing mean wind speed and turbulence profiles representing open-terrain conditions. The results show that the proximity of the test model to the open-jet governs the length of the separation bubble as well as the peak roof pressures. However, test models placed at a horizontal distance of 2.5H (H is height of the wind field) from the exit of the open-jet, with a width that is half the width of the wind field and a length of 1H, have consistent mean and peak pressure coefficients when compared with available results from wind tunnel testing. In addition, testing models with as large as 16% blockage ratio is feasible within the open-jet facility. This reveals the importance of open-jet facilities as a robust tool to alleviate the scale restrictions involved in physical investigations of flow pattern around civil engineering structures. The results and findings of this study are useful for putting forward recommendations and guidelines for testing protocols at open-jet facilities, eventually helping the progress of enhanced standard provisions on the design of low-rise buildings for wind.

• 한국전자거래학회:학술대회논문집
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• 한국전자거래학회 1999년도 종합학술대회발표논문집
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• pp.780-797
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• 1999

ㆍ eProcurement Services ㆍ eBusiness Security Services ㆍ Electronic Data Interchange(EDI) ㆍ Enterprise-scale Project Management and Accountability (omitted)

• Journal of Communications and Networks
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• 제16권5호
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• pp.534-547
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• 2014

Large-scale failures resulting from natural disasters or intentional attacks are now causing serious concerns for communication network infrastructure, as the impact of large-scale network connection disruptions may cause significant costs for service providers and subscribers. In this paper, we propose a new framework for the analysis and prevention of network service disruptions in large-scale failure scenarios. We build dynamic deterministic and probabilistic models to capture the impact of regional failures as they evolve with time. A probabilistic failure model is proposed based on wave energy behaviour. Then, we develop a novel approach for preventive protection of the network in such probabilistic large-scale failure scenarios. We show that our method significantly improves uninterrupted delivery of data in the network and reduces service disruption times in large-scale regional failure scenarios.

• 복합신소재구조학회 논문집
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• 제2권3호
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• pp.1-11
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• 2011

본 연구에서는 하위 요소로(sub-element) 구성된 3차원 대칭 단위 요소들로 조합된 트러스 격자 구조물의 연속적인 물성치를 제안하였다. 개별적인 트러스 격자 물성치는 균질화 작업을 통하여 유효한 응력과 변형률 관계로 이루어진 연속적인 물성치 모델로 나타낼 수 있다. 미시적인 규모(micro scale) 스트럿의 인장이나 압축 응답에 의한 축강성은 전체 격자재료의 대부분의 강도를 차지하고, 이러한 스트럿의 부피 분율(fraction)은 효과적인 강도뿐만 아니라 복제 가능한 단위 요소로 이루어진 격자판의 상대밀도에 큰 영향을 주었다. 그러므로 균질한 강성부재로 구성된 연속적인 구성모델은 미시적인 규모로 간주되는 스트럿의 강도, 내부응력 상태 및 부피 분율과 관련된 역학적인 특성들을 포함하고 있다는 것을 확인할 수 있었다. 미시적인 규모의 응력에서 소성흐름은 균질한 구성식에서 파생된 거시적인 규모에서의 (macro-scale)응력 표면에 있는 연속적인 응력함수의 영역을 확장한다. 따라서 본 연구를 통하여 3차원 대칭 단위요소 구조물의 기본 기하학을 조사하고 압력에 의존적인 마크로 규모에서의 (macro-scale) 응력함수를 예측하는 연속적인 소성모델을 공식화하였다.

• Wind and Structures
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• 제35권2호
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• pp.93-108
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• 2022

Steel tubular towers are commonly used in UHV and long crossing transmission lines. By considering effects of the model scale, the solidity ratio and the ratio of the mean width to the mean height, wind tunnel tests under different wind speeds on twenty tubular steel tower body models and twenty-six tubular steel cross-arm models were completed. Drag coefficients and shielding factors of the experimental tower body models and cross-arm models in wind directional axis for typical skewed angles were obtained. The influence of the lift forces on the skewed wind load factors of tubular steel tower bodies was evaluated. The skewed wind load factors, the wind load distribution factors in transversal and longitudinal direction were calculated for the tubular tower body models and cross-arm models, respectively. Fitting expressions for the skewed wind load factors of tubular steel bodies and cross-arms were determined through nonlinear fitting analysis. Parameters for skewed wind loads determined by wind tunnel tests were compared with the regulations in applicable standards. Suggestions on the drag coefficients, the skewed wind load factors and the wind load distribution factors were proposed for tubular steel transmission towers.

• Structural Engineering and Mechanics
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• 제67권5호
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• pp.527-544
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• 2018

In this paper, the effect of homogenization models on stress analysis is presented for functionally graded plates (FGMs). The derivation of the effective elastic proprieties of the FGMs, which are a combination of both ceramic and metallic phase materials, is of most of importance. The majority of studies in the last decade, the Voigt homogenization model explored to derive the effective elastic proprieties of FGMs at macroscopic-scale in order to study their mechanical responses. In this work, various homogenization models were used to derive the effective elastic proprieties of FGMs. The effect of these models on the stress analysis have also been presented and discussed through a comparative study. So as to show this effect, a refined plate theory is formulated and evaluated, the number of unknowns and governing equations were reduced by dividing the transverse displacement into both bending and shear parts. Based on sinusoidal variation of displacement field trough the thickness, the shear stresses on top and bottom surfaces of plate were vanished and the shear correction factor was avoided. Governing equations of equilibrium were derived from the principle of virtual displacements. Analytical solutions of the stress analysis were obtained for simply supported FGM plates. The obtained results of the displacements and stresses were compared with those predicted by other plate theories available in the literature. This study demonstrates the sensitivity of the obtained results to different homogenization models and that the results generated may vary considerably from one theory to another. Finally, this study offers benchmark results for the multi-scale analysis of functionally graded plates.

• 한국추진공학회지
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• 제17권1호
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• pp.61-69
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• 2013

핀틀 움직임에 의해 발생되는 큰 유동박리에 대해 적합한 2-방정식 난류모델의 압축성계수 보정모델을 판단하기 위하여 수치적 연구를 수행하였다. 난류모델은 저 레이놀즈수 k-${\varepsilon}$ 모델과 k-${\omega}$ SST 모델에 압축성 보정 모델(Wilcox와 Sarkar 모델)을 적용하여, 핀틀 노즐의 세부유동장을 관찰하고 노즐 벽면에서의 압력을 실험데이터와 비교 분석하였다. 마하디스크(Mach disk)의 위치와 박리영역에서의 압력 회복 형태는 난류모델에 따라 다르게 나타났으며, 각 난류모델에 압축성 보정을 적용하여 유동 박리 포획의 정확도를 개선하였다. 압축성이 보정된 k-${\varepsilon}$ 모델이 실험결과와 매우 잘 일치하였다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2020년도 학술발표회
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• pp.172-172
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• 2020

In recent years, soil erosion has come to be regarded as an essential environmental problem in human life. Soil erosion causes various on- and off-site problems such as ecosystem destruction, decreased agricultural productivity, increased riverbed deposition, and deterioration of water quality in streams. To solve these problems caused by soil erosion, it is necessary to quantify where, when, how much soil erosion occurs. Empirical erosion models such as the Universal Soil Loss Equation (USLE) family models have been widely used to make spatially distributed soil erosion vulnerability maps. Even if the models detect vulnerable sites relatively well by utilizing big data related to climate, geography, geology, land use, etc. within study domains, they do not adequately describe the physical process of soil erosion on the ground surface caused by rainfall or overland flow. In other words, such models remain powerful tools to distinguish erosion-prone areas at the macro scale but physics-based models are necessary to better analyze soil erosion and deposition and eroded particle transport. In this study, the physics-based Surface Soil Erosion Model (SSEM) was upgraded based on field survey information to produce sediment yield at the watershed scale. The modified model (hereafter MoSE) adopted new algorithms on rainfall kinematic energy and surface flow transport capacity to simulate soil erosion more reliably. For model validation, we applied the model to the Doam dam watershed in Gangwon-do and compared the simulation results with the USLE outputs. The results showed that the revised physics-based soil erosion model provided more improved and reliable simulation results than the USLE in terms of the spatial distribution of soil erosion and deposition.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2004년도 추계학술대회 논문집
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• pp.413-417
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• 2004

Recent experiments have shown the 'size effects' in micro/nano scale. But the classical plasticity theories can not predict these size dependent deformation behaviors because their constitutive models have no characteristic material length scale. The Mechanism - based Strain Gradient(MSG) plasticity is proposed to analyze the non-uniform deformation behavior in micro/nano scale. The MSG plasticity is a multi-scale analysis connecting macro-scale deformation of the Statistically Stored Dislocation(SSD) and Geometrically Necessary Dislocation(GND) to the meso-scale deformation using the strain gradient. In this research we present a study of nano-indentation by the MSG plasticity. Using W. D. Nix and H. Gao s model, the analytic solution(including depth dependence of hardness) is obtained for the nano indentation , and furthermore it validated by the experiments.