• 제목/요약/키워드: sarcoma

검색결과 974건 처리시간 0.032초

Intraparenchymal Myeloid Sarcoma and Subsequent Spinal Myeloid Sarcoma for Acute Myeloblastic Leukemia

  • Eom, Ki-Seong;Kim, Tae-Young
    • Journal of Korean Neurosurgical Society
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    • 제49권3호
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    • pp.171-174
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    • 2011
  • Myeloid sarcoma is a solid, extramedullary tumor composed of leukemic myeloblasts or immature myeloid cells. Intraparenchymal myeloid sarcoma without the involvement of the skull or meninges is extremely rare. Here, we present the case of a 49-year-old man who developed intraparenchymal myeloid sarcoma on the left cerebellum after allogeneic bone marrow transplantation (BMT). He received radiotherapy after complete removal of intraparenchymal myeloid sarcoma, but he was diagnosed spinal myeloid sarcoma three month later. Nine months after the operation, new intracranial and spinal myeloid sarcoma were diagnosed and the patient's condition had been worsened rapidly. Although the spinal myeloid sarcoma was not histologically diagnosed, this report provides valuable insights into the clinical course of progression of intraparenchymal myeloid sarcoma.

흉벽에 발생한 extraskeletal Ewing sarcoma;치험 1례 (Extraskeletal Ewing`s Sarcoma Arising in the Chest Wall)

  • 왕옥보;김원곤
    • Journal of Chest Surgery
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    • 제25권10호
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    • pp.1107-1111
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    • 1992
  • Extraskeletal Ewing`s sarcoma was first reported by L. Angervall and F.M. Enzinger in 1975. Clinically the tumor affects mainly young adults and children The extraskeletal Ewing`s sarcoma are mainly involved the soft tissues of the trunk and lower extremity. Microscopically. extraskeletal Ewing`s sarcoma is indistinguishable from the Ewing`s sarcoma of bone. We recently experienced a case of extraskeletal Ewing`s sarcoma of the anterior chest wall in a 13-year old female. The patient underwent local wide excision and postoperative radiation and combind chemotherapy were done. This group of tumors has been rarely reported in Korea. We presented a case of extraskeletal Ewing`s Sarcoma in the anterior chest wall with reviw of world literature.

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흉벽에 발생한 골외 Ewing's Sarcoma (Extraskeletal Ewing's Sarcoma Arising in the Chest Wall)

  • 김형우;손홍주;주미;강윤경;전우기;이혁표;김주인;최수전;염호기
    • Tuberculosis and Respiratory Diseases
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    • 제44권5호
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    • pp.1158-1165
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    • 1997
  • Ewing's sarcoma는 청소년기에 대퇴골, 척추주변부, 골반골 등의 뼈에서 흔히 발생하며 드불게 골외에서도 발생하는 종양으로서 특히 흉벽에서의 Ewing's sarcoma의 발생은 흉부 종격동 종양의 감별진단으로 고려해야 할 것으로 사료되며 광범위한 국소적인 절제와 더불어 화학요법 및 방사선 요법으로 좋은 치료 성적을 보이고 있어 골외 Ewing's sarcoma에 대한 정확한 발생부위, 예후 및 치료 방침에 대한 계속적인 연구가 필요할 것이다.

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우측 협부에 발생한 윤활막육종 증례보고 (A Case Report of Synovial Sarcoma of the Face)

  • 허정;이근철;박정민;김석권;노미숙;이진화
    • Archives of Plastic Surgery
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    • 제32권6호
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    • pp.760-762
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    • 2005
  • Synovial Sarcoma is the fourth most common sarcoma, accounting for 8-10 % of all sarcomas. Synovial sarcoma is highly malignant tumor of mesenchymal origin but rarely occurres in head and neck area. Less than 100 cases of synovial sarcoma occurring in head and neck area have been reported all over the world. Pathologically, there is two type of synovial sarcoma: monophasic variant is composed of only one cell type and "classic" (biphasic) synovial sarcoma has two cellular component, a spindle cell(fibrosarcoma-like) component and a pseudoepithelioma component. Recommended treatment is wide resection with negative margins. The role of chemotherapy and radiation therapy is controversial. We experienced a 42-year-old male patient with slowly enlarging, deep seated mass on right cheek. In the first operation, we suggested that the mass maybe benign tumor. But, initial excisional biopsy specimen of the primary lesion was consistent with synovial sarcoma. The final diagnosis was monophasic synovial sarcoma which was composed of spindle cells. Radical resection was performed two months later because remnant tumor was found on follow up MRI. No further treatment was done. There were no recurrence or metastasis on follow up MRI, chest CT and whole body bone scan after 15 months. This is a report of a rare case of synovial sarcoma of the face with a literature review.

Inhibition of Tumor Formation and Changes in Hepatic Enzyme Activities by Kimchi Extracts in Sarcoma-180 Cell Transplanted Mice

  • Hur, Young-Mi;Kim, So-Hee;Park, Jong-Won;Park, Kun-Young
    • Preventive Nutrition and Food Science
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    • 제5권1호
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    • pp.48-53
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    • 2000
  • Inhibitory effects of the methanol extract, hexane extract, methanol soluble fraction (MSF) and juice from 3 weeks fermented Kimchi on the tumor formation in sarcoma-180 cell transplanted mice were studied. Effects of the solvent extracts and juice of the Kimchi on the levels of lipid peroxide, glutathione, and the enzyme activities of the liver were also investigated in normal and sarcoma-180 cell transplanted mice. At 32 days following trans-plantation, MSF reduced the tumor formation by 54% compared with the control group, resulting in the smallest tumor weight. Lipid peroxided content in liver increased by the transplantation of sarcoma-180 cells. However, it decreased when MSF of Kimchi was treated to the mice. MSF also suppressed xanthine oxidase activity in cytosol of the liver cells in mice transplanted by sarcoma-180 cells. Kimchi extracts had no inhibitory effect on hepatic aminopyrine-N-demethylase activity in sarcoma-180 cell transplanted or normal mice. Methanol extract and hexane extract of Kimchi slightly increased hepatic glutathione contents in sarcoma-180 treated mice. The injection of MSF from Kimchi markedly increased glutathione levels in the liver of sarcoma-180 treated mice. The injection of MSF from Kimchi markedly increased glutathione levels in the liver of sarcoma-180 treated mice compared to the controls. The MSF recovered the activities of hepatic glutathione reductase and glutathione S-transferase that decreased by the injection of sarcoma-180 cells. These results showed that MSF of Kimchi could suppress the growth of tumors, inhibiting lipid peroxide production and xanthine oxidase activity, in mice. We also suggested that Kimchi extract might play an important role in the prevention of cancer by enhancement of the glutathione level itself as well as via glutathione reductase and glutathione S-transferase.

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하인두에 발생한 활막육종(Synovial Sarcoma) 1예 (A Case of Synovial Sarcoma of the Hypopharynx)

  • 송달원;김태종;손수길;신호철
    • 대한두경부종양학회지
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    • 제17권2호
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    • pp.226-229
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    • 2001
  • Synovial sarcoma is commonly found in the extremities of mesenchymal origin, but rare in the head and neck area. Histopathology is diagnostic and it shows a biphasic pattern with two neoplastic elements; spindle cell, sarcoma like stroma and gland like clefts lined by epitheloid cells. Synovial sarcoma is high-grade neoplasm that expresses epithelial as well as supporting features. This paper presents a case of synovial sarcoma of hypopharynx on 25 years old male. He was treated by surgical excision and postoperative chemoradiotherapy. There were no evidences of local recurrence & distant metastasis for 19 months postoperatively.

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종골에 발생한 원발성 골육종 - 1예 보고 - (Primary Ostoegenic Sarcoma on Calcaneus - One Case Report -)

  • 조덕연;윤형구;김재화;신동은;박형근
    • 대한족부족관절학회지
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    • 제6권2호
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    • pp.233-237
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    • 2002
  • Osteogenic sarcoma is the most common primary malignant tumor of bone in which tumor cells form neoplastic osteoid or bone or both. Classic osteogenic sarcoma usually involves the metaphysis of the more rapidly growing long bones (distal femur, proximal tibia). Osteogenic sarcoma of the foot is rarely noted and only a few well documented cases have been reported. Osteogenic sarcoma of foot can clinically, radiographically, and histologically mimic several benign lesions and tumor-like lesions, so it sometimes leads to late diagnosis and delayed treatment. We experienced a case of primary osteogenic sarcoma on left calcaneus in 66-years-old female and report it with a review of references.

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원격전이된 미분화성 심장육종의 수술치험 (Surgical Intervention of Undifferentiated Cardiac Sarcoma with Metastases)

  • 신재승;김학제;최영호;김현구;백만종
    • Journal of Chest Surgery
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    • 제33권5호
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    • pp.432-435
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    • 2000
  • We report a case of primary undifferentiated cardiac sarcoma. The tumor originated from the left atrial free wall with multi-organ metastases, e.g., lung, and adrenal gland. The patient gradually grew worse with dyspnea and hemoptysis because of the obstructed left atrial outflow. Surgical resection of the left atrial sarcoma was undertaken to save the patient's life, followed by chemotherapy and brain irradiation as adjuvant therapy. The prognosis of cardiac sarcoma with metastases is very poor. However, in patients with hemodynamic instability, surgical intervention could be a therapeutic modality as palliation.

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Primary Intradural Extraosseous Ewing's Sarcoma

  • Kim, Seok-Won;Shin, Ho
    • Journal of Korean Neurosurgical Society
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    • 제45권3호
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    • pp.179-181
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    • 2009
  • Ewing's sarcoma usually arises from skeletal bone, but rarely may have an extraskeletal origin. However, Ewing's sarcoma that originates around the spinal column, especially, the intradural extramedullary type is extremely rare. We report a rare case of primary intraspinal extraskeletal Ewing's sarcoma.