• Title/Summary/Keyword: safety threshold

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A Study on the Ultrasonic Inspection Method in High Attenuation Welds using Minimization-Polarity Threshold Algorithm (최소극 문턱치 알고리즘을 이용한 고감쇠 용접부에서 초음파 검사방법에 관한 연구)

  • Koo, Kil-Mo;Park, Chi-Seung;Choi, Jong-Ho;Ko, Duck-Young
    • Journal of the Institute of Electronics Engineers of Korea TE
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    • v.37 no.3
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    • pp.30-36
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    • 2000
  • In this paper, an ultrasonic testing method for inspection of high attenuation welding area using the minimum Polarity threshold algorithm which combines the minimum amplitude selection algorithm and polarity threshold algorithm is suggested to increase the signal to noise ratio of the flow signal. In order to confirm the usefulness of the suggested algorithm, experiments were performed using four probes and standard specimens following the ASME Xl Code. As a result, scattering signals were observed from the SE(safe end) and CCSS (centrifugal casting stainless steel) materials due to the microstructural characteristical, and the detectability was reduced due to the highly attenuated signal from the weldment area, but it was conformed that using the suggested algorithm, the signal to noise ratio increased about 2.6.

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Quantitative Detection of Residual E. coli Host Cell DNA by Real-Time PCR

  • Lee, Dong-Hyuck;Bae, Jung-Eun;Lee, Jung-Hee;Shin, Jeong-Sup;Kim, In-Seop
    • Journal of Microbiology and Biotechnology
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    • v.20 no.10
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    • pp.1463-1470
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    • 2010
  • E. coli has long been widely used as a host system for the manufacture of recombinant proteins intended for human therapeutic use. When considering the impurities to be eliminated during the downstream process, residual host cell DNA is a major safety concern. The presence of residual E. coli host cell DNA in the final products is typically determined using a conventional slot blot hybridization assay or total DNA Threshold assay. However, both the former and latter methods are time consuming, expensive, and relatively insensitive. This study thus attempted to develop a more sensitive real-time PCR assay for the specific detection of residual E. coli DNA. This novel method was then compared with the slot blot hybridization assay and total DNA Threshold assay in order to determine its effectiveness and overall capabilities. The novel approach involved the selection of a specific primer pair for amplification of the E. coli 16S rRNA gene in an effort to improve sensitivity, whereas the E. coli host cell DNA quantification took place through the use of SYBR Green I. The detection limit of the real-time PCR assay, under these optimized conditions, was calculated to be 0.042 pg genomic DNA, which was much higher than those of both the slot blot hybridization assay and total DNA Threshold assay, where the detection limits were 2.42 and 3.73 pg genomic DNA, respectively. Hence, the real-time PCR assay can be said to be more reproducible, more accurate, and more precise than either the slot blot hybridization assay or total DNA Threshold assay. The real-time PCR assay may thus be a promising new tool for the quantitative detection and clearance validation of residual E. coli host cell DNA during the manufacturingprocess for recombinant therapeutics.

Review of Factors Affecting IASCC Initiation of Stainless Steel in PWRs (원자로 내부구조물 균열개시 민감도에 미치는 영향인자 고찰)

  • Hwang, Seong Sik;Choi, Min Jae;Kim, Sung Woo;Kim, Dong Jin
    • Corrosion Science and Technology
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    • v.20 no.4
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    • pp.210-229
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    • 2021
  • To safely operate domestic nuclear power plants approaching the end of their design life, the material degradation management strategy of the components is important. Among studies conducted to improve the soundness of nuclear reactor components, research methods for understanding the degradation of reactor internals and preparing management strategies were surveyed. Since the IGSCC (Intergranular Stress Corrosion Cracking) initiation and propagation process is associated with metal dissolution at the crack tip, crack initiation sensitivity was decreased in the hydrogenated water with decreased crack sensitivity but occurrence of small surface cracks increased. A stress of 50 to 55% of the yield strength of the irradiated materials was required to cause IASCC (Irradiation Assisted Stress Corrosion Cracking) failure at the end of the reactor operating life. In the threshold-stress analysis, IASCC cracks were not expected to occur until the end of life at a stress of less than 62% of the investigated yield strength, and the IASCC critical dose was determined to be 4 dpa (Displacement Per Atom). The stainless steel surface oxide was composed of an internal Cr-rich spinel oxide and an external Fe and Ni-rich oxide, regardless of the dose and applied strain level.

Fundamental Research on Spring Season Daytime Sea Fog Detection Using MODIS in the Yellow Sea

  • Jeon, Joo-Young;Kim, Sun-Hwa;Yang, Chan-Su
    • Korean Journal of Remote Sensing
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    • v.32 no.4
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    • pp.339-351
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    • 2016
  • For the safety of sea, it is important to monitor sea fog, one of the dangerous meteorological phenomena which cause marine accidents. To detect and monitor sea fog, Moderate Resolution Imaging Spectroradiometer (MODIS) data which is capable to provide spatial distribution of sea fog has been used. The previous automatic sea fog detection algorithms were focused on detecting sea fog using Terra/MODIS only. The improved algorithm is based on the sea fog detection algorithm by Wu and Li (2014) and it is applicable to both Terra and Aqua MODIS data. We have focused on detecting spring season sea fog events in the Yellow Sea. The algorithm includes application of cloud mask product, the Normalized Difference Snow Index (NDSI), the STandard Deviation test using infrared channel ($STD_{IR}$) with various window size, Temperature Difference Index(TDI) in the algorithm (BTCT - SST) and Normalized Water Vapor Index (NWVI). Through the calculation of the Hanssen-Kuiper Skill Score (KSS) using sea fog manual detection result, we derived more suitable threshold for each index. The adjusted threshold is expected to bring higher accuracy of sea fog detection for spring season daytime sea fog detection using MODIS in the Yellow Sea.

Fatigue Crack Growth Behavior of Gray Cast Iron for Brake Disc of a Passenger Car (대형승용차 디스크 브레이크용 회주철의 피로균열 전파 거동)

  • Kim, Ho-Kyung;Park, Jin-Ho;Yang, Kyoung-Tak;Choi, Deok-Ho
    • Journal of the Korean Society of Safety
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    • v.21 no.4 s.76
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    • pp.19-24
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    • 2006
  • Fatigue crack propagation tests for the brake disc cast iron were conducted for investigating fatigue crack propagation rate(da/dN), crack propagation path and fracture toughness($K_c$) of the material. The threshold stress intensity factor range, ${\Delta}K_{th}$, was found to be about $6MPa{\sqrt{m}}$ at the stress ratio of R = 0.1. Also, fracture toughness value was determined to be $24.7MPa{\sqrt{m}}$. Irregular fatigue fracture surfaces were observed, indicating that fatigue crack growth occurred at the interface between randomly scattered flak graphite and ferrite, where the interfacial strength was relatively weak.

A Study on Flash Flood Warning Trigger Rainfall in Mountainous Area (산악지역 돌발홍수 기준우량 결정에 관한 연구)

  • Jun, Kye-Won;Oh, Chae-Yeon
    • Journal of the Korean Society of Safety
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    • v.24 no.1
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    • pp.89-94
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    • 2009
  • The purpose of this study is to estimate the critical flood discharge and flash flood trigger rainfall for alarm system providing for a flash flood in mountainous area. The flash flood need non-linear approaching method, because rainfall-runoff is nonlinear and it is difficult to explain the existing linear rainfall-runoff. Hydrological characteristics would be utilized to apply such as hydrologic modelling or basin management. This study was effectively estimated a topographic characteristic factor of basin using the GIS. Especially, decided stream order using GIS at stream order decision that is important for input variable of GCIUH. A flash floods defined as a flood which follows shortly after a heavy or excessive rainfall event, with a few hours. In this study, we gave a definition that a critical flood for alarm is the flood when valley depth judging dangerous depth is over 0.5m depth from the bottom of channel. Result that calculate threshold discharge to use GCIUH, at the Mureung valley basin, flash flood trigger rainfall was 16.34mm in the first 20minutes when the threshold discharge was $14.54m^3/sec$.

A novel reconstruction algorithm based on density clustering for cosmic-ray muon scattering inspection

  • Hou, Linjun;Zhang, Quanhu;Yang, Jianqing;Cai, Xingfu;Yao, Qingxu;Huo, Yonggang;Chen, Qifan
    • Nuclear Engineering and Technology
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    • v.53 no.7
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    • pp.2348-2356
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    • 2021
  • As a relatively new radiation imaging method, the cosmic-ray muon scattering imaging technology can be used to prevent nuclear smuggling and is of considerable significance to nuclear safety. Proposed in this paper is a new reconstruction algorithm based on density clustering, aiming to improve inspection quality with better performance. Firstly, this new algorithm is introduced in detail. Then in order to eliminate the inequity of the density threshold caused by the heterogeneity of the muon flux in different positions, a new flux correction method is proposed. Finally, three groups of simulation experiments are carried out with the help of Geant4 toolkit to optimize the algorithm parameters, verify the correction method and test the inspection quality under shielded condition, and compare this algorithm with another common inspection algorithm under different conditions. The results show that this algorithm can effectively identify and locate nuclear material with low misjudging and missing rates even when there is shielding and momentum precision is low, and the threshold correcting method is universally effective for density clustering algorithms.

Algorithm for Determining Whether Work Data is Normal using Autoencoder (오토인코더를 이용한 작업 데이터 정상 여부 판단 알고리즘)

  • Kim, Dong-Hyun;Oh, Jeong Seok
    • Journal of the Korean Institute of Gas
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    • v.25 no.5
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    • pp.63-69
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    • 2021
  • In this study, we established an algorithm to determine whether the work in the gas facility is a normal work or an abnormal work using the threshold of the reconstruction error of the autoencoder. This algorithm do deep learning the autoencoder only with time-series data of a normal work, and derives the optimized threshold of the reconstruction error of the normal work. We applied this algorithm to the time series data of the new work to get the reconstruction error, and then compare it with the reconstruction error threshold of the normal work to determine whether the work is normal work or abnormal work. In order to train and validate this algorithm, we defined the work in a virtual gas facility, and constructed the training data set consisting only of normal work data and the validation data set including both normal work and abnormal work data.

Alternative Sweetener of Sucrose by using Threshold Value and Effects of Salt Addition on the Sweetness (역치를 활용한 설탕 대체 감미료의 적용 및 감미도에 대한 식염의 효과)

  • Hwang Cheol-Seung;Kim Yong-Suk;Shin Dong-Hwa
    • Journal of Food Hygiene and Safety
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    • v.21 no.1
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    • pp.9-13
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    • 2006
  • In this study the expression of the sweetness by using threshold value and effects of salt addition on the sweetness was carried out in model system. Threshold value was 0.4% in sucrose solution and was 0.75-0.80% in the mixture of sweeteners such as low glutinous starch syrup and reduced starch syrup with sucrose solution. The equation between mixture of sweeteners and relative sweetness ($0-20^{\circ}Brix$) on sucrose was induced. The sweetness of red bean paste prepared with low glutinous starch syrup and reduced starch syrup were estimated as 32.78-34.32 by using threshold value, and those lower than 55 of red bean paste prepared with sucrose alone. The synergistic effect of sweetness was observed when 0.05% salt in sugar solution (2.0%) and 0.2% salt in red bean paste were added, respectively. It showed that the addition of salt could be increase the degree of sweetness and decrease the quantity of sweeteners.

A Study on the Priority for the Hazard and Risk Evaluation of Chemicals (HREC) According to the Industrial Safety and Health Act (ISHA) (산업안전보건법 상 관리수준 검토를 위한 화학물질 유해성.위험성 평가대상 후보물질 선정에 관한 연구)

  • Yang, Jeong Sun;Lim, Cheol Hong;Park, Sang Young
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.22 no.1
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    • pp.73-81
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    • 2012
  • Object: The aim of this study is to suggest a list of priority chemicals for the Hazard & Risk Evaluation of Chemicals (HREC) controlled by the Industrial Safety and Health Act (ISHA). Method: Screening assessment was done for 642 chemicals whose exposure threshold limit values were set by the Ministry of Employment and Labor (MOEL). Hazard data were collected from Korea Occupational Safety & Health Agency (KOSHA) and/or other toxicity database. Exposure data were obtained from KOSHA internal database. The hazard and exposure scores of chemicals were listed by order of priority in accordance with GHS classification and exposure index data. Result: From the result of screening risk assessment for 642 chemicals, we extracted a list of 13 priority chemicals for HREC performed by the ISHA. A priority list of 27 chemicals which have carcinogen, mutagen and/or reproductive toxicity but not controlled by the ISHA was suggested for additional evaluation as "chemicals for special management".