• 대한안전경영과학회지
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• 제17권1호
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• pp.67-74
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• 2015

This paper reviewed the relationship between job demands and safety motivation, and the moderating effect of A-type trait in Korean Air Force. Based on the responses from 722 responses, the results of multiple regression analysis appeared as follow; 1) role overload effects positively and role ambiguity effects negatively on intrinsic safety motivation. 2) role conflict effects negatively on extrinsic safety motivation. 3) role ambiguity effects negatively on intrinsic safety motivation in B-type than in A-type trait.

• 약학회지
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• 제47권2호
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• pp.104-109
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• 2003

The present paper reviews the notion and comparison of the Korea Food and Drug Administration(KFDA) general pharmacology and the International Conference on Harmonisation (ICH) safety pharmacology. General pharmacology or safety pharmacology is termed the study to determine the potential of a compound to induce adverse pharmacological effects. KFDA general pharmacology studies have been considered an important component in drug safety assessment and these were originally referred to those designed to examine effects other than the primary therapeutics effect of a drug candidate. The KFDA notified the Guideline for General Pharmacology in 1997. Safety pharmacology studies were focused on identifying adverse effects on physiological functions. In the ICH came into place S7A Safety Pharmacology Studies for Human Pharmaceuticals in 2001. A new chemical entity should be assessed for its side effects, initially in those physiological systems which are generally agreed to be the key systems that are essential for life; these "core system" include the central nervous system, cardiovascular system and respiratory system in safety pharmacology studies. These studies should be performed in compliance with Good Laboratory Practice (GLP).

• Safety and Health at Work
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• 제6권3호
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• pp.159-173
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• 2015

The hand coordinate systems for measuring vibration exposures and biodynamic responses have been standardized, but they are not actually used in many studies. This contradicts the purpose of the standardization. The objectives of this study were to identify the major sources of this problem, and to help define or identify better coordinate systems for the standardization. This study systematically reviewed the principles and definition methods, and evaluated typical hand coordinate systems. This study confirms that, as accelerometers remain the major technology for vibration measurement, it is reasonable to standardize two types of coordinate systems: a tool-based basicentric (BC) system and an anatomically based biodynamic (BD) system. However, these coordinate systems are not well defined in the current standard. Definition of the standard BC system is confusing, and it can be interpreted differently; as a result, it has been inconsistently applied in various standards and studies. The standard hand BD system is defined using the orientation of the third metacarpal bone. It is neither convenient nor defined based on important biological or biodynamic features. This explains why it is rarely used in practice. To resolve these inconsistencies and deficiencies, we proposed a revised method for defining the realistic handle BC system and an alternative method for defining the hand BD system. A fingertip-based BD system for measuring the principal grip force is also proposed based on an important feature of the grip force confirmed in this study.

• Safety and Health at Work
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• 제8권2호
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• pp.189-197
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• 2017

Background: Despite the recent efforts to prevent industrial accidents in the Republic of Korea, the industrial accident rate has not improved much. Industrial safety policies and safety management are also known to be inefficient. This study focused on dynamic characteristics of industrial safety systems and their effects on safety performance in the Republic of Korea. Such dynamic characteristics are particularly important for restructuring of the industrial safety system. Methods: The effects of damping and elastic characteristics of the industrial safety system model on safety performance were examined and feedback control performance was explained in view of cost and benefit. The implications on safety policies of restructuring the industrial safety system were also explored. Results: A strong correlation between the safety budget and the industrial accident rate enabled modeling of an industrial safety system with these variables as the input and the output, respectively. A more effective and efficient industrial safety system could be realized by having weaker elastic characteristics and stronger damping characteristics in it. A substantial decrease in total social cost is expected as the industrial safety system is restructured accordingly. Conclusion: A simple feedback control with proportional-integral action is effective in prevention of industrial accidents. Securing a lower level of elastic industrial accident-driving energy appears to have dominant effects on the control performance compared with the damping effort to dissipate such energy. More attention needs to be directed towards physical and social feedbacks that have prolonged cumulative effects. Suggestions for further improvement of the safety system including physical and social feedbacks are also made.

• 한국안전학회지
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• 제19권1호
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• pp.66-71
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• 2004

This paper describes that the improved effects on the ignition limit are studied by parallel safety components for propane-air 5.25vol.% mixture gas in low voltage inductive circuits. The experimental devices are used in the IEC type spark ignition test apparatus. The improved effects on the ignition limit are respectively obtained as the maximum rising rate of 650%, 1,080% by composing parallel circuits between inductance and safety components (condenser and diode) as compared with disconnecting inductance with the safety components. The more values of inductance the higher improved effects of ignition limit rise. This improving method for the ignition limit is not concerned with the safety components. Diode appears to effect greatly better than condenser. It is considered that the result can be used for not only data for researches and development of intrinsically safe explosion-proof machines which are applied equipment and detectors used in hazardous areas but also for data for its equipment tests.

• Toxicological Research
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• 제27권3호
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• pp.181-184
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• 2011

Screening of estrogenic activity on dichloro diphenyl trichloroethane (DDT), dichloro diphenyl dichloro ethylene (DDE), dieldrin, heptachlor, aldrin, chlordane, lindane, polybrominated diphenyl ethers (PBDE) and parabens was compared using Organization for Economic Cooperation and Development (OECD) test guideline 455 (TG455). The estrogenic activity of DDT was 58,000-fold ($PC_{50}$, $1.67{\times}10^{-6}$ M) less than $17{\beta}$-estradiol($E_2$) ($PC_{50}$, $2.88{\times}10^{-11}$ M) but DDE, dieldrin, heptachlor, aldrin, chlordane, lindane and PBDE did not show any estrogenic activity in this assay system. In the case of paraben compounds, the rank of relative transcriptional activation (logRTA) was butyl paraben -1.63752 ($PC_{50}$, $1.25{\times}10^{-7}$ M) > isobutyl paraben -2.34008 ($PC_{50}$, $6.3{\times}10^{-7}$ M) > ethyl paraben -2.64016 ($PC_{50}$, $1.26{\times}10^{-6}$ M) > isopropyl paraben -2.73993 ($PC_{50}$, $1.58{\times}10^{-6}$ M) > propyl paraben -2.84164 ($PC_{50}$, $2.0{\times}10^{-6}$ M). Our data suggest that OECD test guideline TG455 may be useful as a screening tool for potential endocrine disruptors.

• 한국산학기술학회논문지
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• 제13권2호
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• pp.822-826
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• 2012

본 연구는 CCTV 존재 유무에 따른 보육교사의 안전의식과 안전실천 간의 관계를 실증적으로 분석하였으며, 특히 CCTV 존재 유무와 안전실천 간의 관계에서 안전의식이 매개효과를 가지는지에 대하여도 실증적 분석을 하였다. T-검증 결과 CCTV 존재 유무에 따라 보육교사의 안전의식과 안전실천이 차이가 있음을 검증하였다. 회귀분석 결과 보육교사의 안전의식이 안전실천에 양(+)의 관계로 유의한 것으로 검증되었다. 또한, CCTV 존재 유무가 안전의식을 통해서 안전실천에 영향을 미치는 매개효과에 대해서도 검증되었다. 그 결과 안전의식이 CCTV 존재 유무와 안전실천 사이의 매개변수의 역할을 수행하지 않는다는 결론을 얻었다.

• 대한안전경영과학회지
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• 제7권5호
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• pp.107-117
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• 2005

Zohar(1980) emphasized the influence of social, organizational, and psychological context in occupational safety and health study. With this research trend, Neal, Griffin, and Hart(2000) developed a sequential safety climate model. In this paper, author examined the usability of their model the relationships among safety climates, safety knowledge, safety motivation, and safety performance(safety compliance and safety participation). The author conducted a survey to 207 manufacturing workers, and the chief results of statistical analysis are as follows : 1) the leadership has positive effects on safety knowledge and motivation, 2) the precaution activities has only positive on safety knowledge, 3) the safety system has only on safety motivation, 4) the safety knowledge and motivation have positive effects on safety compliance and participation.

• 한국안전학회지
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• 제36권1호
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• pp.36-43
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• 2021

Effective leadership in safety performance, such as safety leadership, has received attention as a factor that greatly affects safety performance in various high-risk industrial environments. Based on prior research, this study aims to analyze the impact relationship between safety leadership, safety observance, safety education, and safety culture to reveal the effectiveness of safety leadership. In addition, this study will examine the effects of safety leadership on safety observance and safety education to identify the effects of safety understanding. For this purpose, a survey was conducted with employees of an aviation manufacturing company in Gyeongnam. For verification, a positive factor analysis, correlation analysis, and structural equation analysis were conducted using the AMOS 21.0 program. This study's findings show that, first, safety leadership has a positive and significant impact on safety observance and safety education. Second, safety leadership was found to have a direct impact on organizations' safety culture. Third, although safety observance has significant positive effects on safety culture, safety education has often been rejected. Finally, after verifying the control effect of safety understanding, this study uncovered the presence of an adjustment effect in the effect of safety leadership on safety observance. Therefore, based on the results of this study, theoretical and practical implications suggest that through the exercise of safety leadership, managers can improve their organizations' safety culture by increasing organizations' compliance with safety observance and/or acceptance of safety education.

• Nuclear Engineering and Technology
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• 제53권9호
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• pp.3003-3011
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• 2021

A FAC (flow-accelerated corrosion) test was performed for a straight pipe composed of the SA335 Gr P22 and SA106 Gr B (SA106-SA335-SA106) types of steel with welds as a function of the flow rate in the range of 7-12 m/s at 150 ℃ and with DO < 5 ppb at pH levels ranging from 7 to 9.5 up to a cumulative test time of 7200 h using the FAC demonstration test facility. Afterward, the experimental pipe was examined destructively to investigate opposite effects as well as entrance effects. In addition, the FAC rate obtained using a pipe specimen with a 50 mm inner diameter was compared with the rate obtained from a rotating cylindrical electrode. The effects of the complicated fluid flows at the elbow and orifice of the pipeline were also evaluated using another test section designed to examine the independent effects of the orifice and the elbow depending on the distance and the combined effects on orifice and elbow. The tests were performed under the following conditions: 130-150 ℃, DO < 5 ppb, pH 7 and a flow rate of 3 m/s. The FAC rate was determined using the thickness change obtained from commercial room-temperature ultrasonic testing (UT).