• Title/Summary/Keyword: sER

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Position Tracking Control of a Moving Table Using ER Brake/Clutch (ER 브레이크 및 클러치를 이용한 이송 테이블의 위치추적제어)

  • Choi, S.B.;Lee, H.G.;Kim, S.L.;Cheong, C.C.;Han, M.S.
    • Journal of the Korean Society for Precision Engineering
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    • v.15 no.11
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    • pp.208-217
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    • 1998
  • 본 연구에서는 ER 브레이크와 ER클러치를 피드백작동기로 사용하여 이송테이블의 위치 추적제어를 수행하였다. 이를 위해 먼저 아라빅 검(arabic gum)계통의 ER유체를 자체조성한 후 전기장에 대한 빙햄(Bingham)모델을 실험적으로 도출하였다. 빙햄모델에 근거하여 평판형의 ER브레이크와 실린더형의 ER클러치를 설계 제작하였으며, 계단입력(step input)전기장에 따른 출력토오크특성을 통하여 이들 작동기의 동적모델을 얻었다. 이들 작동기와 연계된 이송테이블시스템의 운동지배방정식을 유도한 후 위치추적제어를 위한 슬라이딩모드제어기를 설계하였다. 제어기 설계시 이송해이블의 부하질량 변화에 대한 시스템 불확실성과 마찰력을 고려하여 제어성능의 강건성을 보장하도록 하였다. 제안된 제어시스템의 제어영역(control bandwidth)을 주파수 영역에서 고찰한 후 여러 레적에 대한 위치추적제어 실험을 수행하였다.

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Endoplasmic Reticulum Signaling for Recombinant-protein Production (재조합 단백질 생산을 위한 소포체 신호전달)

  • Goo, Tae-Won;Yun, Eun-Young;Kang, Seok-Woo;Kwon, Ki-Sang;Kwon, O-Yu
    • Journal of Life Science
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    • v.17 no.6 s.86
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    • pp.847-858
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    • 2007
  • The endoplasmic reticulum (ER) is an important intracellular organelle for folding and maturation of newly synthesized transmembrane and secretory proteins. The ER provides stringent quality control systems to ensure that only correctly folded proteins exit the ER and unfolded or misfolded proteins are retained and ultimately degraded. The ER has evolved stress response both signaling pathways the unfolded protein response (UPR) to cope with the accmulation of unfolded or misfolded proteins and ER overload response (EOR). Accumulating evidence suggests that, in addition to responsibility for protein processing, ER is also an important signaling compartment and a sensor of cellular stress. In this respect, production of bio-functional recombinant-proteins requires efficient functioning of the ER secretory pathway in host cells. This review briefly summarizes our understanding of the ER signaling developed in the recent years to help of the secretion capacities of recombinant cells.

In Silico Analysis of Gene Function and Transcriptional Regulators Associated with Endoplasmic Recticulum (ER) Stress (Endoplasmic recticulum stress와 관련된 유전자기능과 전사조절인자의 In silico 분석)

  • Kim, Tae-Min;Yeo, Ji-Young;Park, Chan-Sun;Rhee, Moon-Soo;Jung, Myeong-Ho
    • Journal of Life Science
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    • v.19 no.8
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    • pp.1159-1163
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    • 2009
  • It has been postulated that endoplasmic (ER) stress is involved in the development of several diseases. However, the detailed molecular mechanisms have not been fully understood. Therefore, we characterized a genetic network of genes induced by ER stress using cDNA microarray and gene set expression coherence analysis (GSECA), and identified gene function as well as several transcription regulators associated with ER stress. We analyzed time-dependent gene expression profiles in thapsigargin-treated Sk-Hep1 using an oligonucleotide expression chip, and then selected functional gene sets with significantly high expression coherence which was processed into functional clusters according to the expression similarities. The functions related to sugar binding, lysosome, ribosomal protein, ER lumen, and ER to golgi transport increased, whereas the functions with mRNA processing, DNA replication, DNA repair, cell cycle, electron transport chain and helicase activity decreased. Furthermore, functional clusters were investigated for the enrichment of regulatory motifs using GSECA, and several transcriptional regulators associated with regulation of ER-induced gene expression were found.

Performance Test of 3 Port ERF Valve for Controlling Flow Rate-Direction (3 포트 ERF 밸브의 유량-방향 제어 성능 실험 -유압시스템 및 자동화 융합연구-)

  • Jang, S.C.
    • Journal of Power System Engineering
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    • v.16 no.6
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    • pp.92-97
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    • 2012
  • In this study, ER fluids were working fluid and yield shear stress of attained dispersive ER fluids made by analyzed to adapt effectively at the practical equipment like three port ER valve. In addition, movement of ER particle was observed by using a microscope the same as the strength of electric field with Bingham characteristic. Basis material was presented to develop 3 port ER-Valve by quantitatively comparing and analyzing entrance, load and outlet flow's differences of 3 port rectangular tubes. This study, after designing and producing the 3port ER-Valve, considered the characteristic of pressure drop, outlet and load flow rate by changing the strength of electric field on ER fluids flowing between electrodes.

Performance Investigation of a Continuously Variable ER Damper for Passenger Vehicles (승용차용 연속가변 ER댐퍼의 성능연구)

  • Kim, K.S.;Chang, E.;Choi, S.B.;Cheong, C.C.;Suh, M.S.;Yeo, M.S.
    • Transactions of the Korean Society of Automotive Engineers
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    • v.3 no.6
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    • pp.69-77
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    • 1995
  • This paper presents performance investigation of a continuously variable ER(Electro-Rheological) damper for passenger vehicles. A dynamic model of the damper is formulated by incorporating electric field-dependent Bingham properties of the ER fluid. The Bingham properties are experimentally obtained through Couette type electroviscous measurement with respect to two different particle concentrations. The governing equation of the hydraulic model treating three components of fluid resistances;electrode duct flow, check valve flow and piston gap flow, is achieved via the bond graph method. A prototype ER damper is then designed and manufactured on the basis of parameter analysis. The damping forces of the system are experimentally evaluated by changing the intensity of the electric field, the particle concentration and the electrode gap.

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Electrorheological Properties of ER Fluid under High Shear Flow (고속 전단유동에서 ER유체의 전기유변 특성)

  • Kim Y. C.;Kim K. W.
    • Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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    • 2003.11a
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    • pp.229-234
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    • 2003
  • As electrorheological fluid(ER fluid) has a characteristic that apparent viscosity varies when electric field applied, so rheological characteristic(yield stress & viscosity) changes in proportion to the electric field applied and the response time is very short within a few miliseconds . In case of using ER fluid for journal bearing as lubricant, it is estimated that it's possible to realize very effective journal bearing system that is not complicate and has a very quick response time. It is necessary to examine the influence of rheological characteristic that varies with electric field applied on bearing characteristic to apply ER fluid to journal bearing, however there are few studies for about that. As for the journal bearing, it comes under high shear flow mode that has shear rate range of $10^3\~10^4s^{-1}$ because rotational speed is very high and clearance is small. But most of the studies for about ER fluid issued until now is about the range of $10\~10^2s^{-1}$. So, there are a lot of difficulties to understand the characteristic offish shear flow mode and furthermore it is restricted to make an experiment for about the characteristic of ER fluid because of the limitation of experimental equipment. The equipment was prepared to make an experiment lot high shear flow mode that has the range of $10^3\~10^4s^{-1}$ using ER fluid that is composed of silicon oil with dispersed particle of starch. Using the above system, the fluid characteristic of ER fluid was studied.

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Photoluminescence of Multinary-compound Semiconductor $ZnGaInS_4:Er^{3+}$ Single Crystals (다원화합물 반도체 $ZnGaInS_4:Er^{3+}$ 단결정의 광발광 특성)

  • Kim, Nam-Oh;Kim, Hyung-Gon;Bang, Tae-Hwan;Hyun, Seung-Cheol;Kim, Duck-Tae
    • Proceedings of the KIEE Conference
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    • 2000.07e
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    • pp.35-39
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    • 2000
  • $ZnIn_2S_4$ and $ZnGaInS_4:Er^{3+}$ single crystals crystallized in the rhombohedral (hexagonal) space group $C_{3v}^5(R3m)$, with lattice constants $a=3.852{\AA},\;c=37.215{\AA}$ for $ZnIn_2S_4$, and $a=3.823{\AA}$, and $c=35.975{\AA}$ for $ZnIn_2S_4:Er^{3+}$. The optical absorption measured near the fundamental band edge showed that the optical energy band structure of there compounds had a direct and indirect band gap, the direct and indirect energy gaps are found to be 2.778 and 2.682 eV for $ZnIn_2S_4$, and 2.725 and 2.651eV for $ZnIn_2S_4:Er^{3+}$ at 293 K. The photoluminescence spectra of $ZnIn_2S_4:Er^{3+}$ measured in the wavelength ranges of $500nm{\sim}900nm$ at 10 K. Eight sharp emission peaks due to $Er^{3+}$ ion are observed in the regions of $549.5{\sim}550.0nm,\;661.3{\sim}676.5nm$, and $811.1{\sim}834.1nm$, and $1528.2{\sim}1556.0nm$ in $CdGaInS_4:Er^{3+}$ single crystal. These PL peaks were attributed to the radiative transitions between the split electron energy levels of the $Er^{3+}$ ions occupied at $C_{2v}$, symmetry of the $ZnIn_2S_4$ single crystals host lattice.

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Photoluminescence of $Ga_2S_3$: Er Single Crystals ($Ga_2S_3$: Er 단결정의 Photoluminescence 특성 연구)

  • 진문석;김화택
    • Journal of the Korean Vacuum Society
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    • v.7 no.1
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    • pp.66-71
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    • 1998
  • Two kinds of $Ga_2S_3:Er$ (type A and type B) single crystals were grown by the chemical transport reaction method using iodine as a transport agent. The single crystals were crystallized into a monoclinic structure. The optical energy band gaps were found to 3.375 eV for the $Ga_2S_3:Er$ (type A) single crystal and 3.365 eV fir the $Ga_2S_3:Er$ (type B) single crystal at 13K. When the $Ga_2S_3:Er$ (type A and type B) single crystals were excited by the 325 nm-line of a Cd-He laser, Photoluminescence spectra of the $Ga_2S_3:Er$ (type A) single crystal exhibited blue emission band peaked at 444 nm and green and red emission bands peaked at 518 nm and 690 nm. Pgitikynubescebce soectra if the $Ga_2S_3:Er$ (typeB) single crystal showed green and red emission bands peaked at 513 nm and 695 nm. Sharp emission peaks in the two kinds if $Ga_2S_3:Er$ single crystal were observed near 525 nm, 553 nm, 664 nm, 812 nm, 986 nm, and 1540 nm and analysed as originating from the electron transitions between the energy levels of $Er^{3+}$ ion.

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A 1:1 exercise-to-rest period ratio needed by animals to restore energy sources and replenish anti-oxidative status after exercise

  • Yeom, Ma-Young;Cho, Youn-Ok
    • Nutrition Research and Practice
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    • v.13 no.1
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    • pp.17-22
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    • 2019
  • BACKGROUND/OBJECTIVES: Successful recovery of an animal from exercise is essential, especially prior to the next exercise session. This study was conducted to find an effective exercise-to-rest period ratio for the restoration of energy sources and replenishment of anti-oxidative status in tissue after exercise. MATERIALS/METHODS: Thirty-two rats were assigned to either non-training or training exercise groups for 5 weeks. After that period, the two groups were subdivided into four smaller groups: non-exercise (NE), exercise 0.5 hour and rest 1 hour (ER0.5:1), exercise 1 hour and rest 1 hour (ER1:1), exercise 2 hours and rest 1 hour (ER2:1). RESULTS: In the training group animals and compared to the NE group, the levels of plasma glucose after the rest period were significantly high in all ER groups but highest in the ER2:1 group. Similarly, the liver glycogen level was highest in the ER2:1 group. The plasma FFA level reached the highest level in the ER2:1 group but was similarly high in the ER0.5:1 group. Liver TG level was unchanged in the ER2:1 and ER1:1 groups but was significantly high in the ER0.5:1 group. Muscle TG levels were decreased in all three ER groups. Plasma protein levels were significantly high in the ER2:1 and ER0.5:1 groups. In both training animal and non-training animals, the liver protein levels did not change significantly between the NE and ER groups, irrespective of the exercise-to-rest ratio. In the training animal group, muscle protein level was significantly low in the ER2:1 and ER0.5:1 groups. The activity levels of superoxide dismutase and catalase, as well as the malondialdehyde concentration, were not significantly different between NE and ER groups, irrespective of the exercise-to-rest period ratio. CONCLUSIONS: These results indicate that animals provided with a 0.5:1 to 1:1 exercise-to-rest period ratio can restore their muscle energy sources and recover their anti-oxidative defense system.

Photoluminescence Properties of $CdGaInS_{4}:Er^{3+}$ Single Crystal ($CdGaInS_{4}:Er^{3+}$ 단결정의 광발광 특성)

  • Choe, Sung-Hyu;Kim, Yo-Wan;Kang, Jong-Wook;Lee, Bong-Ju;Bang, Tae-Hwan;Hyun, Seung-Cheol;Kim, Nam-Oh;Kim, Hyung-Gon
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2002.08a
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    • pp.97-100
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    • 2002
  • $CdGaInS_{4}:Er^{3+}$ single crystal crystallized in the rhombohedral. with lattice constants a = 3.899 $\AA$ and c = 36.970 $\AA$ for $CdGaInS_{4}:Er^{3+}$. The optical absorption measured near the fundamental band edge showed that the optical energy band structure of this compound had a direct and indirect band gaps. the direct and indirect energy gaps are found to be 2.665 and 2.479eV for $CdGaInS_{4}:Er^{3+}$ at 10 K. The photoluminescence spectra of $CdGaInS_{4}:Er^{3+}$ measured in the wavelength ranges of 500 nm~900 nm and 1500~1600 nm at 10 K. Eight sharp emission peaks due to $Er^{3+}$ ion are observed in the regions of 549.5~560.0nm. 661.3~676.5nm. 811.1~ 834.1 nm and 1528.2~1556.0 nm in $CdGaInS_{4}:Er^{3+}$ single crystal. These PL peaks were attributed to the radiative transitions between the split electron energy levels of the $Er^{3+}$ ions occupied at $C_{2v}$ symmetry of the $CdGaInS_4$ single crystals host lattice.

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