• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.6
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• pp.1785-1788
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• 2006

Nonalcoholic steatohepatitis(NASH) may progress to advanced liver disease. The diagnosis is made on liver biopsy when investigating a patient with raised transaminases and an otherwise negative biochemical and serological work-up. The subject was a obese male patient who had unexplained raised GOT, GPT. He had no alcoholic consumption and drug ingested. On serological examination, HBsAg and Anti-HCV test are negative. The subject was diagnosed as NASH, and was treated with oriental treatment for obesity. After 2months treatment the raised GOT, GPT decreased to normal range.

• Journal of Life Science
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• v.14 no.2
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• pp.215-220
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• 2004

We investigated the anti-inflammatory effects of aqueous extract of Artemisia capillaris Thunb. (AEAC), a traditional Korean herb for remedying liver disease, for suppression in the process of lipopolysaccharide (LPS)-induced inflammation in the liver of rat. Level of glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT) and lactate dehydrogenase (LDH) was increased in the serum of LPS-treated rats compared to normal, however, in the rats pretreated with AEAC, the increase of GOT, GPT and LDH value was arrested. More severe histological changes of liver such as cloudy swelling, hydropic degeneration, Kupffer cell reaction and inflammatory cells infiltration were demonstrated in the rats challenged with LPS compared with normal. Fewer scores of these changes were observed in rats pretreated with AEAC. Immunohistochemical analysis showed that while the expression of the nuclear factor (NF)-kBp65, inducible nitric oxide synthase (iNOS), tumor necrosis factor (TNF)-$\alpha$ and COX (cyclooxygenase)-2 tended to increase, that of inhibitory (I)-kBa was decreased in the hepatocytes of rats challenged with LPS. A slight decline of NF-kBp65, TNF-$\alpha$ and COX-2, but increase of I-kB$\alpha$ were observed in the hepatocytes of the rats pretreated with AEAC. These results suggest that AEAC may act as a therapeutic agent for liver disease through a regulation of inflammation-related proteins.

• The Journal of the Korea Contents Association
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• v.13 no.11
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• pp.551-561
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• 2013

The purpose of this study was firstly, to evaluate the contents of vocabulary game applications for young children's language learning. and secondly, to examine whether there is any differences between Korean and English word games in terms of the evaluation score. For this purpose, the word game applications in smart phone and tablet PC were analyzed, which included 30 Korean word games and another 30 English ones. The criteria to evaluate the contents were developed based on Children's Software Evaluation Instrument developed by CTR, the multimedia evaluation standard by Hee Sook Park, Young Joo Lee, and mobile contents evaluation standard by Soo Ui Choi. As a result, the educational value got the highest score whereas the design characteristics area got the lowest score in the whole evaluation analysis. And English word game applications mostly got higher score than Korean versions. The result of this study would suggest the way to evaluate educational game applications in use and to contribute to developing educational game contents aimed at young children's language learning.

• Journal of Power System Engineering
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• v.5 no.1
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• pp.11-20
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• 2001

Super-critical type steam power plant, which operates with steam pressure above the super-critical point, has a good reputation recently and is adopted as a new standard of the Korean Electric Power Corporation. The reason for the good reputation lies in it's superior power efficiency. However, the field data of the new power plant for the verification of it's performance are still insufficient, and more empirical data are needed to acquire technologies on the effective operation of it. In this study, the authors analyzed the field test data on power efficiencies got in a super-critical type steam power plant, and evaluated the excellency of the new plant by comparing the efficiency data with the one got in a conventional sub-critical type steam power plant.

• East Asian mathematical journal
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• v.29 no.4
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• pp.449-466
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• 2013

This paper started from a question: Can it help a student solve the problem to give supports in point of view of a teacher knowing the solution. We performed a case study to get an answer for the question. We analysed a case which students do not make full use of data in the mathematical problem from this point of view of the mental representation. We examined closely the cause for not making full use of data. We got that the wrong mental representation which the students get from data in the problem lead to not making full use of data. We knew that it is insufficient to present the data not making use of. To help a student truly, it is necessary to give a aid based on a student's mental representation. From the conclusion of study, We got that figuring out student's mental representation is important and hope that many investigation about student's mental representation for various problem occur with frequency.

• Journal of Fashion Business
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• v.13 no.5
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• pp.1-12
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• 2009

This study looked into the characteristics of participants in dance sports, which is being positioned to be one of everyday athletic activities among people, and investigated the actual purchasing of dance sports wear with the subjects of its participants as a preceding study for the development of dance sports wear to consider their characteristics. The questionnaire method was used, and descriptive and crosstabulation analysis was conducted with a spss 12.0. The findings are as follows. 1. As the results that examine general characteristics of dance sports participants, the number of those in their 20's was the largest, while the number of women was larger than that of men. Regarding the practicing period, those of one year or longer up to 4 years occupied the largest proportion, and the rate of Latin American dance participants was larger than that of modern dance ones. 2. As to the actual purchasing of dance sports wear, the purchase motivations were found to be in the 'contest participation' for teenagers and those in their 20's, while those in their 40's or over purchased their wear for the purposes of 'following the fashion' or 'club gatherings.' As for the sources of information at the time of purchase, teenagers relied on internet and those of 20's or over got the information through the persons nearby. As their ages got higher, the ready-made sports wear was preferred, while as their practicing periods got longer modern dance participants purchased the sports wear of higher prices. Participants in their 30's and those practicing 7 years or longer possessed a comparatively larger number of dance sports wear and they considered importantly of designs and fit at the time of purchase. Therefore, the development of dance sports wear designs should be made to accord with the participants' age groups so that they might be sensitive to the fashion and clearly represent their personality for the junior group and durable enough to last long for the senior group.

• Journal of Life Science
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• v.24 no.6
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• pp.686-693
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• 2014

Restricted supply of nutrients may affect genes at the molecular level as well as physiological functions. Understanding the cellular responses during starvation is necessary for developing strategies to reduce damage caused by starvation stress. After 1 h of starvation, Got1 gene expression was increased but its expression returned to the normal state after 24 h. Mat1 gene expression continuously increased with starvation from 1 h until 24 hr. Rats starved for 1-3 days showed significant changes in expression of the Got1 and Mat1 genes, which were significantly reduced in the cerebral cortex and cerebellum. In the lung, gene expression was increased by starvation for 1-2 days but decreased on the third day. No differences were observed in gene expression in the heart. Strong Got1 lung gene expression was seen in the starvation group one day after restoration of the food supply. Muscle mass was significantly reduced at the start of starvation and remained the same after two days of starvation and one day after the food supply was restored. The Mat1 gene expression did not change. The Got1 was induced by NaCl and showed strong expression in the lung and the thymus, but the apparent decrease of the remaining changes were not observed in male rats. The Mat1 gene was not as sensitive as the Got1 gene to induction by NaCl. However, differences in gene induction by NaCl were evident between males and females, indicating that diet control of gene expression is associated with hormones.

• Korean Journal of Pharmacognosy
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• v.26 no.4
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• pp.390-410
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• 1995

This study was attempted to investigate the effects of Composite Preparation (Samulchungkan-Tang) extract (SCTE), Scutellarias Radix extract (SRE), Artemisiae iwayomogii Herba extract (AIHE), Artemisia capillaris Flos extract (ACFE), Paeaniae Radix extract (PRE) and Gardeniae Fructus extract (GFE) on the activities of GOT, GPT, ALP and LDH, and Content of total cholesterol in serum of $CCl_4$ and ${_D}-galactosamime$ intoxicated rats, and bile flow in rats. 1) In $CCl_4-intoxicated$ rats-The activities of S-GOT and S-GPT which were elevated by $CCl_4$ were significantly decreased in dose of SCTE 450 mg/kg, ACFE 600 mg/kg and GFE 300 mg/kg, respectively as compared to $CCl_4$ intoxicated rats. ALP activity increased by $CC1_4-treatment$ was markedly decreased in dose of SCTE 450 mg and 600 mg/kg, SRE 400 mg/kg, AIHE 400 mg/kg, ACFE 600 mg/kg and PRE 300 mg/kg, and LDH activity in SCTE 450 mg and 600 mg/kg, ACFE 600 mg/kg and GFE 300 mg/kg, respectively compared to $CCl_4$ treated rates. ACFE 400 mg/kg and PRE 300 mg/kg decreased the content of total cholesterol increased by $CCl_4$, the liver weight in all sample administered groups was decreased significantly as compared to $CCl_4$ treated groups. 2) In ${_D}-galactosamine$ intoxicated rats-Sample of SCTE 450 mg and 600 mg/kg, SRE 400 mg/kg, AIHF 400 mg and 600 mg/kg, ACFE 600 mg/kg, PRE 300 mg/kg and GFE 300 mg and 500 mg/kg decreased the activities of S-GPT, ALP and LDH which was increased by ${_D}-galactosamine$ intoxication, compared to ${_D}-galactosamine$ intoxicated groups. In S-GOT activity elevated by ${_D}-galactosamine$ was significantly decreased by SCTE 450 mg/kg, ACFE 600mg/kg, AIHE 600 mg/kg, PRE 300 mg/kg, GFE 300 mg and 500 mg/kg. However, SCTE 600 mg/kg, SRE 400 mg/kg, and AIHE 400 mg/kg were not effected significantly. 3) In bile secretion-SCTE 450 mg and 600 mg/kg, ACFE 600 mg/kg and GFE 500mg/kg increased significantly the amount of bile secretion as compared to normal groups, but AIHE 400 mg/kg, SRE 400 mg/kg, and PRE 300 mg/kg did not effected significantiy.

• Journal of the Korean Society of Food Science and Nutrition
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• v.25 no.5
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• pp.839-845
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• 1996

To investigate effects of Jujube methanol extract on the carbon tetrachloride-induced liver damage in rats, experimental animals were divided into 4 groups; control group(CON), Jujube methanol extracttreated group(JME), $CCl_4$- treated groups(CCl), and Jujube methanol extract and $CCl_4$-treated group (JMC). Each group was sacrificed after 2 or 4week feeding and determined the activities of serum transaminase(GOT, GPT) and hepatic xanthine oxidase, superoxide dismutase(SOD), catalase and glutathione peroxidase(GSH-Px), and hepatic contents of thiobarbituric acid-reactants(TBARS) and glutathione in liver. The activities of sGOT and sGPT, and the hepatic content of TBARS after $CCl_4$-treatment were markedly increased, compared to CON, but those levels were significantly decreased by the pretreatment of Jujube methanol extract, especially in sGOT after 2 and 4 week and TBARS after 4week respectively. Xanthine oxidase activity was increased by $CCl_4$- treatment as compared to CON, but it was also inhibited by the pretreatment of Jujube methanol extract for 2 and 4 week. The activities of SOD, catalase and GSH-Px were elevated by $CCl_4$-treatment, compared to CON, but those elevated activities were showed significant decreasing effect by pretreatment of Jujube methanol extract after 2 and 4week as compared to CON, however, hepatic catalase activity was not affected significantly. These results suggest that Jujube methanol extract is believed to be a possible protective effect for the carbon tetrachloride-induced hepatotoxicity in rats.

• Journal of the Korean Institute of Educational Facilities
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• v.10 no.2
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• pp.15-22
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• 2003

The purpose of this study is to find problems and to provide architectural design standards of the Learning Space Unit(L.S.U.) in Elementary Schools through the Post-occupancy Evaluation(POE). In this study, we found six major problems of the type of the L.S.U. in elementary schools. More than 50% of users expressed dissatisfactions in these items : size, safety, cooling facility, noise, privacy and primary meaning for its original purpose. After the interrelation-analysis, we checked pros and cons about each forms of L.S.U. It is the result of analysis of the layout method in L.S.U. 1) "$8.4m{\times}8.4m$" classroom unit got the highest positive responses 2) "2-classroom type" and "4-classroom type" got higher score than "3-classroom type" 3) "Whole faced type" 1) made more active Multi-space than "Partial faced type" 4) prefered prepared "Open-classroom" to "Closed-classroom" 5) 'Zoning type between L.S.U.s' couldn't influence to user's responses. Designers can consult those informations when they plan a new, remodeling and additional elementary school.