• Molecules and Cells
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• 제20권3호
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• pp.385-391
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• 2005

As a first step towards identifying genes involving in the signal transduction pathways mediating rice blast resistance, we isolated 3 mutants lines that showed enhanced susceptibility to rice blast KJ105 (91-033) from a T-DNA insertion library of the japonica rice cultivar, Hwayeong. Since none of the susceptible phenotypes co-segregated with the T-DNA insertion we adapted a map-based cloning strategy to isolate the gene(s) responsible for the enhanced susceptibility of the Hwayeong mutants. A genetic mapping population was produced by crossing the resistant wild type Hwayeong with the susceptible cultivar, Nagdong. Chi-square analysis of the $F_2$ segregating population indicated that resistance in Hwayeong was controlled by a single major gene that we tentatively named Pi-hy. Randomly selected susceptible plants in the $F_2$ population were used to build an initial map of Pi-hy. The SSLP marker RM2265 on chromosome 2 was closely linked to resistance. High resolution mapping using 105 $F_2$ plants revealed that the resistance gene was tightly linked, or identical, to Pib, a resistance gene with a nucleotide binding sequence and leucine-rich repeats (NB-LRR) previously isolated. Sequence analysis of the Pib locus amplified from three susceptible mutants revealed lesions within this gene, demonstrating that the Pi-hy gene is Pib. The Pib mutations in 1D-22-10-13, 1D-54-16-8, and 1C-143-16-1 were, respectively, a missense mutation in the conserved NB domain 3, a nonsense mutation in the 5th LRR, and a nonsense mutation in the C terminus following the LRRs that causes a small deletion of the C terminus. These findings provide evidence that NB domain 3 and the C terminus are required for full activity of the plant R gene. They also suggest that alterations of the resistance gene can cause major differences in pathogen specificity by affecting interactions with an avirulence factor.

• 수면정신생리
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• 제4권2호
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• pp.201-212
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• 1997

Objectives: We attempted to study sleep habits and insomnia-associated factors in Korean rural adult population. Methods : In 1,441 adult subjects of three rural communities selected by cluster sampling, we administered an epidemiologic survey using questionnaire methods from July 14, 1996 to July 28, 1996. Results : 1) Mean sleep latency and mean time to sleep again after awakening during nocturnal sleep were longer in females than in males. Females suffered more frequently from insomnia symptom, awakening during nocturnal sleep. morning headache, dysphoric mood in the morning, and the feeling of 'not refreshed' on waking-up than males. 2) The older age group (defined as those older than 65 years) was found to have earlier bed-time, longer sleep latency, more frequent nocturia, longer time to sleep again after awakening during nocturnal sleep, and more frequent insomnia symptom. 3) The presence of insomnia symptom more than once a week was significantly associated with suffering from physical illness, being divorced-separated-widowed, frequently feeling depressed, nocturia, or low education level. 4) In multiple logistic regression analysis, old age, being female, low education level, frequently feeling depressed, and nocturia were independently associated with the presence of insomnia symptom more than once a week. Conclusion : We conclude that, in a Korean rural adult population, insomnia symptom increases with age and females usually suffer more from insomnia symptom than males. In addition, low education level, feeling depressed mood frequently, and nocturia are found to be significantly associated independently with the presence of insomnia symptom more than once a week.

• 한국지리정보학회지
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• 제23권3호
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• pp.68-84
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• 2020

본 연구에서는 경상남도 창원시를 대상으로 노인인구 분포지역의 공간적 특성과 폭염과의 관계를 분석하였다. 이를 위해 통계청의 인구센서스 자료와 환경부 토지피복도, Landsat 8 지표면온도, 기상청의 폭염일수 자료를 활용하였다. 노인인구 분포의 공간적 특성은 토지이용특성을 고려하여 K-mean 군집화 분석을 통해 총 5개 유형으로 분류하였다. 공간유형별 노인인구 특성은 도시화된 유형(cluster-3)에서 노인인구의 수가 많았으나, 농촌지역과 산림지역에 분포하는 유형(cluster-1, cluster-2)에서는 노인인구의 구성 비율이 높은 것으로 나타났다. 지표면온도와 폭염일수 특성에서는 도시지역에서 지표면온도가 가장 높았으나 폭염일수는 농촌지역이 가장 많았다. 노인인구 분포지역의 공간유형에 따른 폭염 특성을 분석한 결과, 농촌지역 면적이 많은 cluster-2가 15.95일로 가장 높았고, 도시화된 유형인 cluster-3은 9.41일로 가장 낮았다. 즉, 도시지역에 거주하는 노인인구보다 농촌지역에 거주하는 노인인구가 폭염에 더욱 노출되어 있으며, 피해가 가중될 것으로 예상된다. 본 연구의 결과는 여름철 폭염 취약지역의 효과적인 관리와 사전 예방을 위한 다양한 정책방안을 마련하는데 기초적인 자료로 활용될 수 있을 것이다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권19호
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• pp.8455-8460
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• 2014

Background: The National Central Cancer Registry of China (NCCR) affiliated to the Bureau of Disease Control, National Health and Family Planning Commission of China is responsible for cancer surveillance in the entire country. Cancer registration data from each local registry located in each province are collected by NCCR annually to be analyzed and published to provide useful information for policy makers and cancer researchers. Materials and Methods: Until 1st June, 2013, 219 population-based cancer registries submitted data of 2010 to the National Central Cancer Registry of China covering about 207,229,403 population, and 145 cancer registries were selected after quality evaluation for this study. Colorectal cancer cases were selected from the database according to ICD-10 coded as "C18-C20". We calculated the crude incidence and mortality rates by sex, age groups and location (urban/rural). The China population in 2000 and Segi's population were used as standardized populations for the calculation of age-standardized rates. The 6th National Population Census data of China was used to combined with the cancer registries' data to estimate the colorectal cancer burden in China in 2010. Results: Colorectal cancer was the sixth most common cancer in China. It was estimated that there were 274,841 new cases diagnosed in 2010 (157,355 in males and 117,486 in females), with the crude incidence rate of 20.1/100,000, highest in males in urban areas. Age-standardized rates by China standard population of 2000 (ASRcn) and World standard population (Segi's population, ASRwld) for incidence were 16.1/100,000 and 15.9/100,000 respectively. There were 132,110 cases estimated to have died from colorectal cancer in China in 2010 (76,646 men and 55,464 women) with the crude mortality rate of 10.1/100,000. The ASRcn and ASRwld for mortality were 7.55/100,000 and 7.44/100,000 respectively, higher in males and urban areas than in females and rural areas. The incidence and mortality rates increased with age, reaching peaksin the 80-84 year old, and oldest age groups, respectively. Conclusions: Colorectal cancer is one of the most common incident cancers and cause of cancer death in China. Primary and secondary prevention, with attention to a health lifestyle, physical activity and screening should be enhanced in the general population.

• 한국지역지리학회지
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• 제10권4호
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• pp.744-756
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• 2004

본 연구의 목적은 상주권에 위치한 미작과 과수 농업 중실 마을의 자연 환경, 사회 경제 환경의 변화를 밝히는 것이다. 연구 결과는 세 가지로 요약될 수 있다. 첫째, 상주권 촌락의 대부분은 소백산맥의 침식 분지와 낙동강의 퇴적지형에 위치해 있으며, 이러한 자연 환경은 지역 주민의 삶에 많은 영향을 미쳤다. 둘째, 1970년대까지 상주군 촌락의 인구는 지역 내부에서 이루어진 재생산 구조에 의해 유지되어 왔다. 이후 농촌 마을의 자녀들이 직장, 교육 등의 이유로 타 지역, 특히 대도시로 이농함에 따라 지역 내에서 이루어진 인구 재생산 구조가 더 이상 유지될 수 없었다. 셋째, 1980년대 이후 상주권 촌락은 재배 작물과 이와 관련된 생산 양식에 따라 상이한 경로로 변화하였다. 벼와 밭작물에 기반을 둔 전통적 생산 양식을 지속시킨 촌락과 과수 농사에 기초한 상업적 생산 양식으로 전환한 촌락의 사회 경제 구조는 상이한 경로로 변화하였다. 함창읍 척동 1리는 전자의 경로로 그리고 모동면 신천 2리는 후자의 경로로 따라 변화하여 왔다.

• 보건의료산업학회지
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• 제7권3호
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• pp.287-296
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• 2013

The aim of this study was to compare the regional difference of death from intentional self-harm. The analysis was based on data of intentional self-harm deaths (31,450) from the 2010-2011 vital statistics of Korea. The suicide rate (per 100,000 population) was 46.2 in male and 22.3 in female. Gender ratio (male / female) of suicide rate was 2.07, and Jeju province had the lowest gender ratio (1.82), and Chungbuk province had the highest gender ratio (2.42). In the age-gender standardized death rate (per 100,000) of self-harm by region, the highest suicide rate was observed in Gangwon province (44.8) and Chungnam province (44.3), and the lowest in Seoul metropolitan city (28.9) and Ulsan metropolitan city (29.2). There was a significant increase in the rate of suicide in city areas (odds ratio: 1.11, 95% CI: 1.08-1.13), county areas (1.62, 1.56-1.67) as compared with the rate of suicide in metropolitan areas. The commonest methods of suicide were hanging (53.7 percent), self-poisoning by pesticides (16.8 percent) and jumping from a height (14.3 percent). The methods used for suicide differed between rural (county) and urban areas (metropolitan city and city). In county areas, 43 percent of suicides used pesticides as compared to only 7-18 percent of those in urban areas. In urban areas, jumping was more common (13-17 percent vs. 6 percent). There were no difference in hanging between urban and rural areas. The odds ratio of death by pesticides was 9.86 in rural areas compared with death rate of metropolitan areas. The odds ratio of death by jumping was 0.59 in rural compared with death rate of metropolitan areas.

• Asian Pacific Journal of Cancer Prevention
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• 제13권6호
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• pp.2991-2995
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• 2012

Background: India shows some of the highest rates of cervical cancer worldwide, and more than 70% of the population is living in rural villages. Prospective cohort studies to determine the risk factors for cervical cancer are very rare from low and medium resource countries. The aim of this study was to quantify the effect of risk factors related to cervical cancer in a rural setting in South India. Material and methods: Sociodemographic and reproductive potential risk factors for cervical cancer were studied using the data from a cohort of 30,958 women who constituted the unscreened control group in a randomised screening trial in Dindigul district, Tamilnadu, India. The analysis was accomplished with the Cox proportional hazard regression model. Results: Women of increasing age (HR=2.4; 95% CI: 1.6, 3.8 in 50-59 vs 30-39), having many pregnancies (HR=7.1; 1.0, 52 in 4+ vs 0) and no education (HR=0.6; 0.2, 0.7 in high vs none) were found to be at significantly increased risk of cervical cancer. Conclusion: This cohort study gives very strong evidence to say that education is the fundamental factor among the sociodemographic and reproductive determinants of cervical cancer in low resource settings. Public awareness through education and improvements in living standards can play an important role in reducing the high incidence of cervical cancer in India. These findings further stress the importance of formulating public health policies aimed at increasing awareness and implementation of cervical cancer screening programmes.

• 한국농촌건축학회논문집
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• 제14권3호
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• pp.1-8
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• 2012

Due to difficulty of marriage with women in Korea, unmarried men in countryside tend to have an international marriage. A ratio of international marriage was 3.7% in 2004, but increased by over 10% in 2004 due to the change of population composition in countryside. Without social or national preparation on a multicultural family and an increase of elder who lives alone made problems such as changes of population composition in countryside, a high rate of divorce due to differences on culture and society. These problems are becoming critical problems in countryside, not only for a family. This Study has a purpose as below, Firstly, this study will examine living place of elder who live alone and multicultural families. Secondly, characteristics of using each space will be analyzed and then surveyed efficiency and satisfaction. The result of survey will be provided to space planning for improvement of living standard. The results of this study can be summarized as follows: The characteristics of the surveyed households, the elderly ratio of 70 to 80 units high, and when the elderly become less than 10 years, 51.6%, 77.4% of women were overwhelmingly high. The characteristics of multicultural families in the in the middle or early 2000s when immigration is concentrated and national origin in Vietnam was 66.7 %. Housing characteristics of households with elderly housing type, the ratio improved to 61.3% is Majority. Type strain and 29% in traditional houses, traditional housing type is 9.7%. And house of multicultural families improve housing type is 87.5% Majority. The main space of the housing for the elderly, most are usually satisfied. But generally low level of self-determined housing survey confers real. These results have lived a long time because of space adaptation and can be viewed as attachment. For the elderly passive use of space and simplify the Act and heating cooling at the expense of the use of housing space due to the reduction, but multicultural families is the space required for the growth of their children because there are more modifications required.

• 농촌지도와개발
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• 제19권4호
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• pp.1041-1066
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• 2012

농촌정책의 중요한 과제는 농촌 지역경제 활성화인데, 대다수 연구와 정책은 농업인과 농업을 중심으로 전개되고 있다. 그러나 지역경제 활성화는 지역 내의 다양한 산업이 얽혀 내외부의 변화에 반응하는 것으로 어느 한 부분의 성장만으로 농촌 지역경제 활성화는 달성되기 어렵다. 본 연구는 이러한 문제점을 바탕으로 충청남도 5개 군을 대상으로 농촌지역에서 농업부문의 위치를 살펴보고, 농촌에 위치한 산업별 변화요인을 살펴보았다. 분석결과 5개 군에서 농림어업은 수위산업으로서 역할을 담당하고 있으며, 지역 내부요인인 지역산업효과, 지역경쟁효과가 매우 취약함을 보여 5개 군에서 지역경제 활성화를 위해서는 위와 관련한 요인들의 성장을 위한 노력이 필요한 것으로 분석되었다. 또한 농림어업부분은 지역 외부효과에 의해 영향을 많이 받고 있었으며, 도소매업, 숙박 및 음식점업 등 농촌 지역에 기초수요를 제공하는 산업부문의 감소가 두드러지게 나타나고 있었다. 이러한 연구결과가 농촌지역에 주는 시사점은 다음과 같다. 우선 농림어업 내 생산물의 지역내 소비와 연결시키는 노력을 통해 지역산업과 연결시키는 개선이 필요할 것이며, 농촌지역 주민의 기초서비스를 제공하는 업종의 보호를 위한 정책적 수단마련을 위해 읍면소재지 개발 등의 사업내용에 소상공인 지원을 위한 사업내용의 고려가 필요하다.

• 농촌의학ㆍ지역보건
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• 제10권1호
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• pp.5-15
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• 1985

It has been a long tradition in the field of nutrition that the degree of malnutrition in a community used to be estimated by the degree of the adequacy of nutrients consumption in the households. The adequacy of nutrient consumption in the households then used to be applied to estimate the degree of malnutrition of the children. Such a practice is theoretically acceptable in the community where the food sharing within the household is individual serving style such as in European countries. However, the community where the dietary habit in the household is communal such as in Korea, the estimation of single serving portion from household consumption is quite uncertain. Because of such an uncertainty this study is intended to test the validity of the household food consumption level as an indication of nutritional status of the children in the rural farm households in Korea. The date from the household consumption survey in 1982 by the Korean Rural Nutrition Institute has been used for the analysis of food consumption levels of the households. The survey on the nutritional status of children of 127 preschool children from 78 farm households, has been conducted during May 1983. The nutritional status of the children has been directly measured by weight, height, skinfold thickness, haemoglobin, haematocrit and morbidity of influenza and diarrhoea. The analysis has been conducted to distinguish the differences in prevalence of malnutrition of children from the estimated of household consumption and that of from the direct measurement of nutritional status of children. The results show that the degree of malnutrition of the estimated by the household consumption level has not related with the prevalence of malnutrition by the direct measures of nutritional status of the children. Therefore, the validity of household consumption level as an indication of nutrional status in a same household is quite uncertain for the population studied.