• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.5 no.1
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• pp.32-42
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• 1987

Global change and local fluctuation of earth's gravity field play important roles in accurate vertical positioning as well as in accurate horizontal positioning. Regarding the impotance, in this study, the concept of gravity potential theory connected with the influence of gravity field and every kind of height were discussed. Various kind of heights using the observed gravity and leveling data were computed and analysed to study the influence of earth's gravity field in accurate vertical positioning. Taking the route from Busan to Kyongju and investigating the ratios ($\Delta$H/dH) of height defferences (dH) between calculated heights considering gravity field and leveling height to relative heights (dH) between adjacent stations, we get the result that the values by correction formula increase linearly according to latitude, and the values by gravity potential ere strongly influenced by pseudo topography.

• Toxicological Research
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• v.16 no.1
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• pp.83-87
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• 2000

This study was carriet out to evaluate the acute intravenous toxicity and antigenicity of Guamerin, newly developed by Mogam Biotechnology Research Institute (MBRI). In acute intravenous toxicity test, ICR mice were administered intravenously with single dose of 1,000mg/kg, and body weights and clinical signs were observed for 14 days. No dead animal, clinical signs, body weight change and abnormal autopsy findings were found in control and Gumerin treated group. Therefore, the 50% lethoal dose (LD50) of Guamerin for ICR mice was more than 1,000mg/kg on intravenous route for male and female. And the antigenic potential of Guamerin was examined by active systemic anaphylaxis(ASA) and passive cutaneous anaphylaxis(PCA) tests. In the ASA test, low and high doses (10 and 100ug/animal, respectiwely) of Guamerin were administed subcutaneously to guinea pigs for 9 times 3 weeks. All experimental groups showed negative responses whereas the positive control group given ovalbumin plus Freunds complete adjuvant (FCA) showed severe anaphylactic responses. PCA test using rats with mice anti-serum against Guamerin, low and high doses(10 and 100 ug/animal, respectively) of Guamerin were administered to mice for 9 times in 3 weeks. The anti-serum against Guamerin was administed intradermally at the back of rats, however, any positive responses were not detected in the experimental groups. These results strongly indicate that Guamerin does not induce IgE production and is not a PCA reaction inducer under these experimental conditions.

• KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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• v.26 no.1
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• pp.11-17
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• 2020

This study conducted a case study and a questionnaire analysis in parallel. In the case study, a study was conducted on domestic manufacturer A by analyzing pallet loading efficiency of RRP(Retail Ready Packaging) products and pallet loading efficiency of MWC(Membership Wholesale Club) delivered products. As a result of the pallet loading efficiency simulation of 50 RRP products of Manufacturer A, it was 80.0% based on the T-11 type pallet and 84.3% based on the T-12 type pallet. It was found It refers that the route of producing the product from the manufacturer A and delivering it to the MWC A in the form of RRP resulted in the decrease of the pallet loading efficiency through the change of the loading pattern and the adjustment of the number of loads. As a result of analyzing the questionnaire about whether the overall efficiency of the supply chain will be improved if the operation of the packaging system considering the SCM(Supply Chain Management) aspect is χ² = 178.500, there was a statistically significant difference at the significance level of 0.000. Manufacturers and logistics companies answered "yes" the most, but distributors answered "is average" the most, confirming that the packaging can be constructed with the highest operational efficiency. Therefore, as a result of confirming the impact of packaging design considering the SCM aspect on logistics efficiency, it indicates the importance of closer collaboration between manufacturers and distributors.

• The Korean Journal of Pain
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• v.13 no.2
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• pp.259-262
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• 2000

There are many difficulties in the management of terminal cancer pain. We often encounter difficulties when nerve blocks or epidural injection of drugs do not produce good results. Local anesthetics, opioids and adjunctives, were administered to two patients intrathecally. The results were very satisfactory. It has complications such as hypotension or infection due to intrathecal route. In the first case, the pancreatic cancer patient complicated with severe epigastic pain but unfortunately no management was effective in pain control. Intrathecal injection of bupivacaine and morphine mixture was successful even if syncope which was relieved by bed rest. In the second case, the patient complicated with lower abdominal pain due to ovarian cancer who very well controlled by epidural injection of morphine and clonidine mixture but morphine demand was greatly increased. Intrathecal injection of morphine and ketamine were tried. The patient had comportable analgesic effect. CSF leakage to subcutaneous occurred but resolved by change of the catheter position or retunnelling. There were no significant complications reported in two cases.

• Journal of Korean Institute of Industrial Engineers
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• v.37 no.2
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• pp.144-152
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• 2011

Most of the models for the vehicle routing problems studied in the literature assumed constant travel times. However, those approaches may give infeasible solutions when traffic congestion causes delays in travel time. To overcome such difficulty, there have been some researches considering the change of the travel time which is called the time dependent vehicle routing problem (TDVRP). TDVRP assumes that the travel time between two locations is not only affected by the distance traveled, but by many other factors including the time of the day. In this paper, we propose a branch-and-price algorithm to solve the TDVRP. The time dependent property of the travel time is dealt with an enumeration scheme with bounding procedures in the column generation procedure identifying a profitable route. The proposed algorithm guarantees the "Non-passing" property to be held in the solutions. The algorithm was tested on problems composed of the Solomon's benchmark instances for 25 and 50 nodes. Computational results are reported.

• The Korean Journal of Pain
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• v.14 no.2
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• pp.171-175
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• 2001

Background: This purpose of this study is to compare the analgesic efficacy, occurrence of motor block and other side effects of 48 hr continuous postoperative epidural infusions with 0.125% ropivacaine with fentanyl or 0.15% ropivacaine with fentanyl. Methods: Forty patients undergoing Cesarean section were randomly allocated into two groups. Both groups received epidural injection of 2.0% lidocaine 19 ml and 0.75% ropivacaine 2-5 ml with fentanyl $50{\mu}g$ for 20 minutes before surgery. Following surgery, a continuous epidural infusion using a two- day infusor was given for 40 minutes for post-operative pain control. Group 1 (n = 20) then received 0.125% ropivacaine and 6 ug/ml of fentanyl at a rate of 2 ml/h. Group 2 (n = 20) received 0.15% ropivacaine and 6 ug/ml of fentanyl at the same rate. Visual analog scales (VAS) for pain during rest and movement, sensory change and motor blockade were assessed for 48 hr after surgery. Results: There were no significant differences in VAS for pain during rest or movement. The incidence of side effects was similar in both groups. Conclusions: Using 0.125% ropivacaine with fentanyl via an epidural route provided similar pain relief and side effects as 0.15% ropivacaine with fentanyl.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.9
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• pp.5835-5843
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• 2014

This study examined the Hanghae-Gamsa's (the local governor of Hanghae-Do) utilization of the governing institutions in Hanghae-Do during the Sulryeok (an inspection tour around the Gamsa's ruling area). For this purpose, the four Hanghae-Gamsa's official diaries were closely investigated, which were written from the 18th century to the early 19th century. The main results of this study are as follows: 1) the routes of Hanghae-Gamsa's Sulryeok and some sightseeing parts; 2) the arrival route of newly appointed Hwanghae-Gamsa and the site of Gyogwui (the change-over ritual ceremonies) between old and new Hwanghae-Gamsas; and 3) utilization of governing institutions in Hanghae-Do during the Sulryeok focusing on his duties and ritual ceremonies.

• Journal of Korean Neurosurgical Society
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• v.40 no.1
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• pp.22-27
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• 2006

Objective : The purpose of this study is to investigate the clinical results of anterior and posterior stabilization by one stage posterolateral approach for the unstable fracture of thoracolumbar and lumbar spine. Methods : By posterolateral approach with curved skin incision, unilateral facet and pedicle were removed. Through this route, corpectomy was performed, and then this space was replaced with mesh cage filled up with autologous bone graft. Both side pedicle screw fixation was followed to upper and lower levels. Results : Six of seven patients of this study showed neurological improvement. The other one patient showed no neurological change. One patient had postoperative infection, another patient had postoperative kyphosis. The other patient had epidural hematoma on operation site after surgery. And all patinets on this study made to have spinal stability except one patient happened postoperative kyphosis. Conclusion : In the unstable fracture of thoracolumbar and lumbar spine, one stage anterior and posterior stabilization and fusion by posterolateral approach seems to be an effective procedure, if we have more care and supplementation.

• Journal of Sasang Constitutional Medicine
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• v.22 no.2
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• pp.101-107
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• 2010

1. Objectives: The aim of this study is to investigate the acute toxicity and safety of Taeeumjowi-tang. 2. Methods: We investigated the acute toxicity for water-extracted Taeeumjowi-tang. 25 male and 25 female mice were observed for 14 days after one day oral administration of Taeeumjowi-tang at the respective doses of 0(control group), 2560, 3200, 4000 and 5000 mg/kg. 3. Results: We observed survival rates, general toxicity, change of body weight and autopsy. 4. Conclusions: The data confirmed that Taeeumjowi-tang is free from the toxicity and safety problems in oral route respectively. Compared with the control group, we could not find any toxic alteration in all treated groups(2560, 3200, 4000 and 5000 mg/kg). In conclusion, LD50 of Taeeumjowi-tang was over 5000 mg/kg and it is very safe to mice.

• Transactions of Materials Processing
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• v.15 no.6 s.87
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• pp.441-444
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• 2006

The deformation behavior of copper during equal channel angular pressing(ECAP) was calculated using a three-dimensional version of a constitutive model based on the dislocation density evolution. Finite element simulations of the variation of the dislocation density and the dislocation cell size with the number of ECAP passes are reported. The calculated stress, strain and cell size are compared with the experimental data for Cu deformed by ECAP in a modified Route C regime. The results of FEM analysis were found to be in good agreement with the experiments. After a rapid initial decrease down to about 200nm in the first ECAP pass, the average cell size was found to change little with further passes. Similarly, the strength increased steeply after the first pass, but tended to saturate with further pressings. The FEM simulations also showed strain non-uniformities and the dependence of the resulting strength on the location within the workpiece.