• 대한간호학회지
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• 제36권3호
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• pp.523-531
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• 2006

Purpose: The purpose of this study was to examine the effects of the ulmus root-bark dressing on tissue regeneration in experimentally-induced pressure ulcers in rats. Method: A randomized pretest/post-test control group time-series study design was used. Thirty-three male Sprague-Dawley rats were used in this study. The rats were anesthetized with 100mg/kg of ketamine. Pressure ulcers were induced at 140mmHg for three hours using a personally-designed pressing apparatus. For four weeks, the ulmus root-bark dressing was applied every other day in the experimental group (n=18) and a wet gauze dressing in the control group (n=15). For data analysis, the statistical program SPSS WIN 12 was used. The wounds were examined by light microscopy andelectron microscopy. Result: There were significant statistical differences in the size of the pressure ulcers as time went by(p=0.006). It should be noted that there were no significant statistical differences in the number of capillaries. Using light microscopy the inflammatory infiltration and neovascularization in the dermis in the experimental group emerged densely in the early stages, but recovered rapidly at the latter stages. In addition, the reepithelization of the epidermis occurred earlier than in the control group. By electron microscopy, the cell organelles of the capillary endothelial cells and the basal lamina of capillaries in the experimental group showed a more rapid maturation during the latter stages, compared with the control group. Conclusion: According to this study, it can be concluded that the ulmus root-bark dressing is effective regarding the healing of pressure ulcers.

• Restorative Dentistry and Endodontics
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• 제26권2호
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• pp.111-120
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• 2001

Calcium hydroxide pastes is widely used in conventional endodontics. Along with the expanded clinical use of calcium hydroxide, literatures suggest mixing calcium hydroxide with other substance. Among added substances the vehicle plays the most importance role in the overall process because it is directly related with the velocity of ionic dissociation of $Ca^{2+}$ and OH ion. In this study, we evalutated and compared periapical tissue response and root resorption after canal was filled with mixture of saline and calcium hydroxide(Junsei Chemical Co.. Japan) as a aqueous vehicle, Metapaste(Meta Co., Korea) as a viscous vehicle paste, Vitapex(Neo Dental, Japan) as a oily vehicle paste and IRM(Caulk Dentsply, USA) in replantation of rat molar. A total of 31 maxillary first molars of Sprague-Dawley female rats, 30 days old were used. The upper 1st molar was extracted and the mesiobuccal canal was filled with mixture of saline and calcium hydroxide, Metapaste, Vitapex. IRM and then replanted. Rats were sacrificed 3 weeks after replantation. the maxillae were removed. section of 4 micron were cut and stained with hematoxylin-eosin, Apical tissue response were observed under light microscope. The results were as follows: 1. Saline mixing group and Metapaste group were significant different in fibrous capsule width compared to Vitapex group and IRM group(P<0.05). 2. Saline mixing group. Metapaste group. Vitapex group and IRM group did not prevent root resorption and there were no statistical difference. 3. In saline mixing group and Metapaste group. loss of pastes were observed in all samples. From the results of our study. we observed loss of pastes in saline mixing group and Metapaste group because of water soluble property and assumed it was related to inflammation in apical area and sealing ability of material. So, we should study and develop calcium hydroxide vehicle which is easily removed and more stable and because of only 3 weeks observation we need more evaluation in long period.

• Journal of Periodontal and Implant Science
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• 제48권6호
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• pp.395-404
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• 2018

Purpose: The purpose of this study was to propose a technique for periodontal biotype modification through thickening of the entire facial aspect using a volume-stable collagen matrix and autogenous subepithelial connective tissue graft (CTG) for the treatment of gingival recession. Methods: Four systemically healthy patients showing Miller class I or class II gingival recession in the mandibular incisor area were included in this study. Full-mouth scaling and root planing procedures were performed at least 4 weeks prior to periodontal plastic surgery. A split-thickness flap with a horizontal intrasulcular incision and 2 vertical incisions was used in cases 1-3, and the modified tunnel technique was used in case 4 for coronal advancement of the mucogingival complex. After the exposed root surfaces were debrided thoroughly, double-layered volume-stable collagen matrix was placed on the apical part of the recession and a subepithelial CTG harvested from the palatal area was placed on the coronal part. The amount of root coverage at 3 months postoperatively was evaluated in cases 1-3, and facio-lingual volumetric changes were analyzed in cases 1 and 2. Results: Healing was uneventful in all 4 cases and complete root coverage was shown in cases 1-3. In case 4, reduction of gingival recession was observed at 3 months after surgery. In cases 1 and 2, a comparison of stereolithographic files from the preoperative and postoperative time points demonstrated that the entire facio-lingual volume had increased. Conclusions: The surgical technique suggested herein, using a volume-stable collagen matrix and autogenous subepithelial CTG, may be an effective method for periodontal biotype modification through thickening of the entire facial aspect for the treatment of gingival recession.

• Journal of Periodontal and Implant Science
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• 제54권4호
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• pp.265-279
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• 2024

Purpose: The aim of current study was to evaluate percentage root coverage (RC%) in isolated Miller class III/RT2 labial gingival recession (GR) associated with malaligned mandibular anteriors, using interdisciplinary periodontal-orthodontic treatment as compared to mucogingival surgery alone. Methods: Thirty-six systemically healthy patients having isolated Miller class III/RT2 GR with respect to malaligned mandibular anteriors, were randomly divided into test group: mucogingival surgery using subepithelial connective tissue graft followed by orthodontic treatment and control group: mucogingival surgery alone. Primary clinical parameters included (RC%), recession depth, keratinized tissue width, mid-labial clinical attachment level, interdental clinical attachment level (iCAL), periodontal phenotype (PP), gingival thickness (GT), root coverage esthetics score (RES) and hypersensitivity. Total duration of follow up was 12 months. Results: Mean RC% was significantly more achieved in test group (66.67%±40.82%) in comparison to control group (39.93%±31.41%) at the end of study (P=0.049). Further, complete root coverage was attained in 5/8 cases of test group versus 1/2 cases of control group after 3/12 months respectively. RES and hypersensitivity, showed statistically significant improvement after complete follow up period in both the groups. An ideal RES score of 10 was achieved in 4/7 cases of test group while in 1/2 cases of control group after 3/12 months respectively. Correlation analysis revealed significant negative correlation between RC% and iCAL. Correlation of RC% with GT and PP was non-significant. Conclusions: Interdisciplinary periodontal-orthodontic approach may be more beneficial in terms of achieving improved RC%, esthetic and resolution of hypersensitivity in the management of Miller class III/RT2 GR in malaligned mandibular anteriors.

• Journal of Periodontal and Implant Science
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• 제51권2호
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• pp.77-87
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• 2021

Purpose: The aim of this study was to compare the efficacy of the tunnel technique for root coverage using a new xenogeneic acellular dermal matrix vs. connective tissue grafting (CTG) for the treatment of multiple maxillary adjacent recessions (recession type 1) at 12 months postoperatively. Methods: This study enrolled 12 patients with at least 3 contiguous, bilateral, symmetrical maxillary gingival recessions (i.e., at least 6 recessions per patient). In total, 74 recessions were treated using the modified coronally advanced tunnel (MCAT) technique combined with a novel porcine-derived acellular dermal matrix (PADM) at 37 test sites or CTG at 37 control sites. The following clinical parameters were measured: recession height, clinical attachment level, width of keratinized tissue, probing depth, recession width, gingival thickness, mean root coverage (MRC), and complete root coverage (CRC). Comparisons between test and control groups were made for pain visual analog scale scores at 14 days. Results: At 12 months, the MCAT with PADM (test) yielded a statistically significant improvement in all clinical parameters studied. MRC was significantly higher on the control sides (80.6%±23.7%) than on the test sides (68.8%±23.4%). Similarly, CRC was 48.7%±6.8% on the control sides (CTG), in contrast to 24.3%±8.2% on the test sides (PADM). Statistically significant differences were observed in favor of the control sides for all clinical parameters studied. Nevertheless, the MCAT in adjunction with PADM was clearly superior at reducing mean and maximum patient-reported postoperative pain intensity and pain duration in the first week after surgery. Conclusions: The use of PADM to treat multiple recessions improved clinical parameters at 12 months, but these outcomes were nevertheless poorer than those observed for CTG. However, PADM reduced morbidity, particularly the pain experienced by patients.

• Journal of Ginseng Research
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• 제28권3호
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• pp.157-164
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• 2004

인삼재배지에서 나타나는 적변삼 외피세포 조직의 특성과 화학성분을 조사하였던 바 그 결과를 요약하면 다음과 같다. 1. 적변외피는 현미경 관찰결과 적색이 아닌 황색으로 보였으며, 적변외피의 세 포층수는 10∼13층으로 건전외피의 5∼6층에 비해 2배 정도 많았고, 외피층의 두께에 있어서는 적변외피가 179 $\mu\textrm{m}$로서 건전외피의 55$\mu\textrm{m}$에 비해 3.2배 정도 더 두꺼웠다. 2. 착색도는 적변외피가 건전외피에 비해 5.5배 정도 짙게 나타났으며, 적변물질의 각 추출분획별 용해도는 비극성 보다는 극성용매에서 높았고, 또한 UV-spectrum은 275∼280nm에서 흡광 최대를 나타냈다. 3. 적변외피는 지질성 물질은 물론 산불용성 에스테르화 페놀물질, 산불용성 결합 페놀물질, 산불용 축합성 페놀물질, 불용성 결합 페놀물질 및 유리 페놀 물질 함량이 건전외피에 비해 많았으며 철의 함량에 있어서도 적변외피가 2,220 ppm으로 건전외피의 820 ppm 보다 2.7배 정도 많았다. 4. 적변삼은 인삼뿌리가 분포된 근권환경의 어떤 외적환경에 의해 뿌리가 stress를 받을 때 자체방어 물질인 phenol 물질이 외피로 배출되면서 외피의 지질성 물질과 polymerization되고 이때 철(Fe)이 체놀성 물질과 강하게 chelating 되는 것으로 추정된다.

• 대한치주과학회:학술대회논문집
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• 대한치주과학회 1997년도 제37회 종합학술대회 연제초록
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• pp.97-97
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• 1997

• 대한치주과학회:학술대회논문집
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• 대한치주과학회 2009년도 춘계학술대회
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• pp.34-34
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• 2009

• 대한치주과학회:학술대회논문집
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• 대한치주과학회 2003년도 제43회 종합학술대회 연제초록
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• pp.21-21
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• 2003

• 한국연초학회지
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• 제16권2호
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• pp.97-101
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• 1994

Tobacco stalks were cut and removed from the field after harvest, and urea was treated by placing it on the cutting portions of the remaining tobacco stumps. Relative virus infectivity of the root residue(compared to the fresh root residue infected with TMV) was reduced to 14.6% in December, 1993(before overwintering) and to 8.5% in March, 1994 just before transplanting, indicating that the TMV infectivity decreased remarkably, but was preserved still in the root residue in the field soil. There was no significant difference in infectivity of remaining root tissue between the treated and untreated root residue. However, as roots with urea treatment had been extensively decayed, only about one - fifth of the initial root volume remained after overwintering. TMV occurred less (by one - third) in the urea treatment than in the control, suggesting that urea treatment effectively provented tobacco from TMV infection by reducing the inoculum potential.