• Title/Summary/Keyword: role of laboratory work

Search Result 114, Processing Time 0.028 seconds

The Intelligent Clinical Laboratory as a Tool to Increase Cancer Care Management Productivity

  • Mohammadzadeh, Niloofar;Safdari, Reza
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.6
    • /
    • pp.2935-2937
    • /
    • 2014
  • Studies of the causes of cancer, early detection, prevention or treatment need accurate, comprehensive, and timely cancer data. The clinical laboratory provides important cancer information needed for physicians which influence clinical decisions regarding treatment, diagnosis and patient monitoring. Poor communication between health care providers and clinical laboratory personnel can lead to medical errors and wrong decisions in providing cancer care. Because of the key impact of laboratory information on cancer diagnosis and treatment the quality of the tests, lab reports, and appropriate lab management are very important. A laboratory information management system (LIMS) can have an important role in diagnosis, fast and effective access to cancer data, decrease redundancy and costs, and facilitate the integration and collection of data from different types of instruments and systems. In spite of significant advantages LIMS is limited by factors such as problems in adaption to new instruments that may change existing work processes. Applications of intelligent software simultaneously with existing information systems, in addition to remove these restrictions, have important benefits including adding additional non-laboratory-generated information to the reports, facilitating decision making, and improving quality and productivity of cancer care services. Laboratory systems must have flexibility to change and have the capability to develop and benefit from intelligent devices. Intelligent laboratory information management systems need to benefit from informatics tools and latest technologies like open sources. The aim of this commentary is to survey application, opportunities and necessity of intelligent clinical laboratory as a tool to increase cancer care management productivity.

Switchable Uncompensated Antiferromagnetic Spins: Their Role in Exchange Bias

  • Lee, Ki-Suk;Kim, Sang-Koog;Kortright J.B.;Kim, Kwang-Youn;Shin, Sung-Chul
    • Journal of Magnetics
    • /
    • v.10 no.1
    • /
    • pp.36-39
    • /
    • 2005
  • We report element-resolved and interface-sensitive magnetization reversals investigated from an oppositely exchange-biased NiFe/FeMn/Co structure by employing soft x-ray resonant Kerr rotation measurements. We have found not only switchable uncompensated antiferromagnetic regions with its sizable thicknesses at both interfaces of the FeMn layer but also their strong coupling to the individual ferromagnetic layers. These experimental results provide a better insight into experimentally observed reductions in exchange-bias field on the basis of an interface-proximity model proposed in this work.

A New Broadband Microstrip-to-SIW Transition Using Parallel HMSIW

  • Cho, Dae-Keun;Lee, Hai-Young
    • Journal of electromagnetic engineering and science
    • /
    • v.12 no.2
    • /
    • pp.171-175
    • /
    • 2012
  • In this work, a new microstrip-to-substrate integrated waveguide (SIW) transition using the parallel half-mode substrate integrated waveguide (HMSIW) is proposed. The proposed transition consists of three sections : a microstrip, parallel HMSIWs, and an SIW. By inserting the parallel HMSIWs section between the microstrip section and the SIW section, the proposed transition can improve the return loss characteristics of the near cut-off frequency because the HMSIWs section has a lower cut-off frequency than the SIW section (8.6 GHz). The lower cut-off frequency is achieved through gradual electromagnetic field mode changes for a low reflection. The measured return loss is less than 20 dB in the of 9.1~16.28 GHz freqeuncy range for the back-to-back transition. The measured insertion loss is within 1.6 dB for the back-to-back transition. The proposed transition is expected to play an important role in wideband SIW circuits fed by a microstrip.

Identification of HPV Integration and Genomic Patterns Delineating the Clinical Landscape of Cervical Cancer

  • Akeel, Raid-Al
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.16 no.18
    • /
    • pp.8041-8045
    • /
    • 2016
  • Cervical cancer is one of the most common cancers in women worldwide. During their life time the vast majority of women become infected with human papillomavirus (HPV), but interestingly only a small portion develop cervical cancer and in the remainder infection regresses to a normal healthy state. Beyond HPV status, associated molecular characterization of disease has to be established. However, initial work suggests the existence of several different molecular classes, based on the biological features of differentially expressed genes in each subtype. This suggests that additional risk factors play an important role in the outcome of infection. Host genomic factors play an important role in the outcome of such complex or multifactor diseases such as cervical cancer and are also known to regulate the rate of disease progression. The aim of this review was to compile advances in the field of host genomics of HPV positive and negative cervical cancer and their association with clinical response.

A Study on the Space Planning and Formal Design of Nursing Lab (대학 간호학 실습실의 공간구성 및 형태계획에 관한 연구)

  • Lee, Joo-Hye
    • Proceedings of the Korean Institute of Interior Design Conference
    • /
    • 2007.05a
    • /
    • pp.67-70
    • /
    • 2007
  • The meaning of the space planning which has from modern interior space has played important role, space composition planning itself is the concept creation tool as well as the unique expression sphere in field of interior space far away from fixed idea relevant to the existing space which was only simple division or secondary element in design. Thus, this current work expresses that the space-Function is related with space-division as well as basic designed-conceptual work process including the space is formed. Furthermore, through the side-composition with form, it activates the various space aspect perceptually, which created the visual environment in using lightning, reflection of glass and penetrated nature etc. The keyword on elevation design concept is as like various aspects, third dimension, non-materiality and symbolical meaning. In addition, it provides the color space equipped with functionality and artistry capable to arouse the diverse sensual capacity to space users on default of image language.

  • PDF

Study on Legal Issues and Scope of Medical Technologist's Practice (임상병리사 업무 범위와 법률적 고찰)

  • Shim, Moon-Jung;Koo, Bon-Kyeong;Park, Chang-Eun
    • Korean Journal of Clinical Laboratory Science
    • /
    • v.49 no.2
    • /
    • pp.55-68
    • /
    • 2017
  • In recent years, medical practice has seen a drastic change due to the rapid, exponential expansion of scientific and medical technologies. Specially, the role of medical technologists (also known as medical laboratory scientists and/or clinical laboratory scientists) are increasing in the development of science of medical technology. As such, their responsibility has also been increasing. Therefore, given their highly specialized knowledge and skills, they are not regarded solely as doctor's assistants. Their independence and deeper specialization have been increasing, as they perform medial practices under the guidance of doctors or dentists pursuant to the "Act on Medical Service Technologists." From a legal point of view, medical guidance and scope of work were examined. As a conclusion, the definition of doctor's superintendency on the "Act on Medical Service Technologists" is required, and the qualification for the Korean license examination and their roles should be stated clearly. Moreover, communications among health professions regarding the roles of medical technologists are necessary to further facilitate clarification of their role. There is a need for independent legislation to expand the field of medical technologists and to strengthen their professionalism.

Critical buckling analyses of nonlinear FG-CNT reinforced nano-composite beam

  • Zerrouki, Rachid;Karas, Abdelkader;Zidour, Mohamed
    • Advances in nano research
    • /
    • v.9 no.3
    • /
    • pp.211-220
    • /
    • 2020
  • This paper investigates the effect of linear and non-linear distribution of carbon nanotube volume fraction in the FG-CNTRC beams on the critical buckling by using higher-order shear deformation theories. Here, the material properties of the CNTRC beams are assumed to be graded in the thickness direction according to a new exponential power law distribution in terms of the carbon nanotube volume fractions. The single-walled carbon nanotube is aligned and distributed in the polymeric matrix with different patterns of reinforcement; the material properties of the CNTRC beams are described by using the rule of mixture. The governing equations are derived through using Hamilton's principle. The Navier solution method is used under the specified boundary conditions for simply supported CNTRC beams. The mathematical models provided in this work are numerically validated by comparison with some available results. New results of critical buckling with the non-linear distribution of CNT volume fraction in different patterns are presented and discussed in detail, and compared with the linear distribution. Several aspects of beam types, CNT volume fraction, exponent degree (n), aspect ratio, etc., are taken into this investigation. It is revealed that the influences of non-linearity distribution in the beam play an important role to improve the mechanical properties, especially in buckling behavior. The results show that the X-Beam configuration is the strongest among all different types of CNTRC beams in supporting the buckling loads.

Effect of cyclodextrin glucanotransferase enzyme in biodegradation of diesel oil

  • Sivaraman, C.;Ganguly, Anasuya;Mutnuri, Srikanth
    • Advances in environmental research
    • /
    • v.1 no.2
    • /
    • pp.97-108
    • /
    • 2012
  • Microbial degradation of hydrocarbons is found to be an attractive process for remediation of contaminated habitats. However the poor bioavailability of hydrocarbons results in low biodegradation rates. Cyclodextrins are known to increase the bioavailability of variety of hydrophobic compounds. In the present work we purified the Cyclodextrin Glucanotransferase (CGTase) enzyme which is responsible for converting starch into cyclodextrins and studied its role on biodegradation of diesel oil contaminated soil. Purification of CGTase from Enterobacter cloacae was done which resulted in 6 fold increase in enzyme activity. The enzyme showed maximum activity at pH 7, temperature $60^{\circ}C$ with a molecular weight of 66 kDa. Addition of purified CGTase to the treatment setup with Pseudomonas mendocina showed enhanced biodegradation of diesel oil ($57{\pm}1.37%$) which was similar to the treatment setup when added with Pseudomonas mendocina and Enterobacter cloacae ($52.7{\pm}6.51%$). The residual diesel oil found in treatment setup added with Pseudomonas mendocina at end of the study was found to be $73{\pm}0.21%$. Immobilization of Pseudomonas mendocina on alginate containing starch also led to enhanced biodegradation of hydrocarbons in diesel oil at 336 hours.

Antitumor and antioxidant activities of Bryonia laciniosa against Ehrlich's Ascites Carcinoma bearing Swiss albino mice

  • Sivakumar, T;Kumar, R Sambath;Perumal, P;Vamsi, MLM;Sivakumar, P;Kanagasabai, R;Baskaran, MV;Karki, Subhas S;Mazumder, UK;Gupta, M
    • Advances in Traditional Medicine
    • /
    • v.5 no.4
    • /
    • pp.322-330
    • /
    • 2005
  • The plant Bryonia laciniosa (Family: Cucurbitaceae) has been indicated for the treatment of various diseases one among which is cancer. The purpose of this study was investigating experimentally the possible anti-tumor effect and antioxidant role of Bryonia laciniosa leaves in animal model. The methanol extract of Bryonia laciniosa (MEBL) administered at the doses of 62.5, 125 and 250 mg/kg in mice for 14 days after 24 h of tumor inoculation. The effect of MEBL on the growth of transplantable murine tumor, life span of EAC bearing mice, hematological profile and liver biochemical parameters (lipid peroxidation, antioxidant enzymes) were estimated. Treatment with MEBL decreased the tumor volume and viable cell count thereby increasing the life span of EAC bearing mice and brought back the hematological parameter more or less normal level. The effect of MEBL also decreases the levels of lipid peroxidation and increased the levels of glutathione (GSH), superoxide dismutase (SOD) and catalase (CAT). The present work indicates that the methanol extract of Bryonia laciniosa exhibited significant antitumor and antioxidant activity in vivo.

Complexity Estimation Based Work Load Balancing for a Parallel Lidar Waveform Decomposition Algorithm

  • Jung, Jin-Ha;Crawford, Melba M.;Lee, Sang-Hoon
    • Korean Journal of Remote Sensing
    • /
    • v.25 no.6
    • /
    • pp.547-557
    • /
    • 2009
  • LIDAR (LIght Detection And Ranging) is an active remote sensing technology which provides 3D coordinates of the Earth's surface by performing range measurements from the sensor. Early small footprint LIDAR systems recorded multiple discrete returns from the back-scattered energy. Recent advances in LIDAR hardware now make it possible to record full digital waveforms of the returned energy. LIDAR waveform decomposition involves separating the return waveform into a mixture of components which are then used to characterize the original data. The most common statistical mixture model used for this process is the Gaussian mixture. Waveform decomposition plays an important role in LIDAR waveform processing, since the resulting components are expected to represent reflection surfaces within waveform footprints. Hence the decomposition results ultimately affect the interpretation of LIDAR waveform data. Computational requirements in the waveform decomposition process result from two factors; (1) estimation of the number of components in a mixture and the resulting parameter estimates, which are inter-related and cannot be solved separately, and (2) parameter optimization does not have a closed form solution, and thus needs to be solved iteratively. The current state-of-the-art airborne LIDAR system acquires more than 50,000 waveforms per second, so decomposing the enormous number of waveforms is challenging using traditional single processor architecture. To tackle this issue, four parallel LIDAR waveform decomposition algorithms with different work load balancing schemes - (1) no weighting, (2) a decomposition results-based linear weighting, (3) a decomposition results-based squared weighting, and (4) a decomposition time-based linear weighting - were developed and tested with varying number of processors (8-256). The results were compared in terms of efficiency. Overall, the decomposition time-based linear weighting work load balancing approach yielded the best performance among four approaches.