• 대한전자공학회논문지SP
• /
• 제39권1호
• /
• pp.1-8
• /
• 2002

RGB 칼라 필터 배열을 사용한 순차주사 CCD 이미지 센서는 센서의 구조적 한계를 극복하고 칼라 신호의 해상도를 향상시키기 위해 칼라 보간 구조가 필요하다. 기존의 접근 방법을 통해 보간된 결과 영상 대부분에서 경계선은 열화되고 재현된 칼라는 원영상의 칼라와 차이가 났다. 본 논문에서는 순차주사 CCD 이미지 센서를 위한 개선된 경계적응적 칼라 보간 구조를 제안했다. 제안된 경계 표시자(edge indicator) 함수는 채널내 상관관계 뿐만 아니라 채널간의 상관관계를 이용하며 주어진 영상의 경계 특성을 칼라 보간 과정에 적응적으로 반영한다. 주어지지 않은 채널 값은 경계를 거스르는 방향이 아니라 경계 방향을 따라서 보간되고, 에일리어징 현상(aliasing artifacts)은 억제가 됐다. 또한 경계적응적 칼라 보간 구조의 단순한 칼라 영상 형성 모델로부터 발생하는 국소적으로 나타나는 잘못된 색을 칼라 경계 검출법에 기반한 스위칭 알고리즘에 의해 제거하였다. 개선된 경계적응적 칼라 보간 구조는 기존의 접근 방법에 비해 주관적 화질과 객관적 화질 모두 우수한 결과를 실험적으로 보였다.

• 한국항만경제학회지
• /
• 제17권2호
• /
• pp.139-166
• /
• 2001

Globalization and regionalization are major trends in the international economic system. The severe competition among countries has signalled the need for a new international trade system as prescribed by the WTO, which regulates international trade practices. Additionally, expanding the activities and role of the Pan-Yellow Sea area in the world has a very important function in terms of regional cooperation and logistics environment. In this paper, the trading conditions and shipping transport problems of the Pan-Yellow Sea area (North-East Asia) were investigated. Shipping transport conditions in the Pan-Yellow Sea area, particularly Korea-China routes, were surveyed as well. A new Incheon-China container liner route was suggested as a partial remedy to some of the shipping transport problems of the Pan-Yellow Sea Area (North-East Asia). The Incheon-China Container Liner route is more efficient than Pusan and Pyungtaek Ports or the car ferry route to China in terms of transport time and expense. The transport burden indicator which includes the time and expense of transport, can be a useful tool in comparing these routes. Accordign to the transport burden indicator, the Incheon-China Container Liner route is more efficient than the Pusan, Pyungtaek, or car ferry routes. To establish a successful liner route between the ports of Inchon and China, there is a need to prepare three measures that contain short-term medium-term and long-term strategies. Furthermore, these measures should be prepared and adopted in phases, in accordance with considerations of future conditions for shipping and logistics in the Pan-Yellow Sea area.

• 대한미생물학회지
• /
• 제35권3호
• /
• pp.225-237
• /
• 2000

Vibrio vulnificus, a halophilic vibrio is an estuarine gram-negative bacteria that is associated with severe and frequently fatal wound infections and life-threatening septicemia. Bacteriocins are defined as antibacterial substance produced by various species of bacteria which are usually active against closely related organisms. Bacteriocins have found widespread application in epidemiological studies as specific markers of bacteria. It was proposed by Ha et al. (1990. J. Korean. Soc. Microbiol. 25: 586.) to give the bacteriocins produced by V. vulnificus the name "vulnificins". In the present study, a total of 72 strains of V. vulnificus isolated from patients and oysters were subjected to screen potential producers and indicators of vulnificin, applying ultraviolet induction method. Sensitivity of several strains of Serratia marcesans, Pseudomonas aeruginosa, Shigella flexneri, Salmonella typhi and Yersinia enterocolitica to vulnificins were also examined out. All the tested strains of V. vulnificus produced vulnificins active against indicator strains with various different inhibitory patterns. The spectrum of vulnificin activity and sensitive spectrum of indicator strains were considerably broad. Interestingly, almost all strains of S. marcescens, P. aeruginosa, Salmonella sp., Shigella sp. and Y. enterocolitica tested were sensitive to 1-7 vulnificin(s). Taken together, the present study demonstrated that all of the isolates of V. vulnificus produced vulnificins and that 8 good vulnificin producers and 10 good indicators were detected. These strains can be employed efficiently for establishing vulnificin typing scheme of V. vulnificus and for the detection of bacteriocinogeny and sensitivity in V. vulnificus. Biological role of vulnificin remains to be further elucidated.

• 한국어병학회지
• /
• 제29권1호
• /
• pp.25-33
• /
• 2016

In human medicine, circulating microRNAs have been successfully utilized as early biomarkers for various abnormalities and disease states. Vertebrate miR-122 is a liver-specific microRNA which is expressed almost solely in hepatocytes and plays an important role in the regulation of hepatocyte function. In this study, to evaluate the potential utility of circulating miR-122 as a biomarker for liver injury in olive flounder (Paralichthys olivaceus), fish were orally intubated with two doses of acetaminophen (500 mg/kg or 1.000 mg/kg of body weight), and the expression of miR-122 in serum was quantified using real time-PCR. Histological change in liver, and the enzymatic activity of glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) were also analyzed. The results showed that miR-122 was higher in acetaminophen administered groups compared to control group. The histopathological effect of acetaminophen on olive flounder liver was not distinct. The serum level of GPT and GOT was increased within 2 folds compared to control group by acetaminophen administration. However, the serum miR-122 level was increased more than 3 or 4 folds compared to the control group by administration of 1000 mg/kg of acetaminophen. These results suggest the possible use of miR-122 as an indicator of liver injury in olive flounder, even when histopathological effects are not distinctive.

• 가정과삶의질연구
• /
• 제32권5호
• /
• pp.193-205
• /
• 2014

The purpose of this research is to gather basic data to make nursery teachers' role clear and to suggest a way to improve their expertise by investigating their sensitivity and expertise. To fulfill this aim, this research was performed by targeting 180 nursery teachers responsible for infant classes in national, public, and private nursery schools. To measure the nursery teachers' sensitivity, Gerber's (2003) teacher sensitivity indicator is used. And to measure the efficacy of teaching play, the indicator, which was developed by E. Shin, Y. Yu and H. Park (2004), was used through modification and complement. Also for measuring the teacher's expertise, research data were collected by the generalized and modified questionnaire which was used in H. Yoon's (2010) research. The results of the analysis of collected data show that the teacher group with higher sensitivity in the infant class shows meaningfully higher professional ethics, higher performance, and higher recognition of expertise than the teacher group with lower sensitivity. And the teacher group with higher awareness of the efficacy of play shows higher professional ethics, higher performance, and higher recognition of expertise than the teacher group with lower sensitivity. too. Also, the results of the analysis of the correlation between the infant teacher's sensitivity, efficacy of teaching play, and recognition of expertise show that the teacher's sensitivity has a static correlation with the total points of social necessity, professional ethics, fairness, teacher's performance, and recognition of expertise. When we generalize the research results, we find that positive sensitivity and higher efficacy of teaching play make the infant class teacher's expertise recognition higher.

• Annals of Clinical Neurophysiology
• /
• 제15권2호
• /
• pp.42-47
• /
• 2013

Background: Diffusion-weighted image (DWI) might be useful to predict the prognosis of acute hypoxic encephalopathy. The aim of our study was to test whether the early change and extent of DWI abnormalities can be an indicator of the clinical outcome of hypoxic encephalopathy. Methods: Forty-four patients who were diagnosed as hypoxic encephalopathy due to the cardiorespiratory arrest were retrospectively identified. Clinical variables were determined, and the DWI abnormalities were counted by four areas: cortex, subcortical white matter, cerebellum and deep grey matter, and were divided into three groups by the extent of lesions. Prognosis was classified as 'poor' (Glasgow coma scale (GSC) at 30 days after arrest <9 or death) and 'good' (GSC at 30 days after arrest ${\geq}9$). Results: GCS at day 3 (p<0.001), presence of seizure (p=0.01), and presence of lesion (p<0.001) were significantly different in prognosis, but statistically there is no association with the extent of lesions and prognosis (p=0.26). Conclusions: Presence of early DWI changes could predict the clinical outcome of hypoxic encephalopathy after cardiorespiratory arrest.

• 한국건설관리학회논문집
• /
• 제7권5호
• /
• pp.77-84
• /
• 2006

지수는 여러 산업분야에서 오랜시간 동안 경제지표 또는 성과지표로서 중요한 역할을 담당해 왔으며, 실적공사비 적산방식이 적용 확대됨에 따라 2004년 2월부터 시간에 대한 보정을 위하여 건설공사비지수를 사용하고 있다. 건설공사비지수를 산출하기 위한 구성요소는 지수산정식과 자료원으로 구분된다. 기존의 건설관련 공사비지수에서는 물가지수산정에 사용하는 라스파이레스(Laspyeres)지수를 산정식으로 적용하고 산업연관표, 공사비 내역서를 사용하여 가중치를 산정하였다. 그러나, 기존의 방법은 물가변동이 중복 적용되고 대상프로젝트의 특성을 효과적으로 반영하지 못하는 문제점이 발생된다. 본 연구에서는 라스파이레스지수를 비롯한 기존 지수 산정식들을 분석하고, 공동주택공사의 사례를 통하여 기존 지수산정식 및 자료원의 적정성을 분석한 후, 건설공사의 특성을 효율적으로 반영하고 물가변동을 반영할 수 있는 새로운 지수를 제안한다.

• 한국정보통신학회논문지
• /
• 제11권1호
• /
• pp.198-205
• /
• 2007

유비쿼터스 환경에 있는 사용자는 현재 자신의 위치, 시간 그리고 주변의 상태에 기반한 상황 인식 서비스를 받을 수 있다. 이러한 상황 인식 컴퓨팅에서 위치 기반서비스는 매우 중요한 역할을 한다. 위치를 측정하기 위하여 전용 장비를 설치하고 운영하는 데 많은 비용이 소요되기 때문에 기존의 WLAN(Wirless Local Area Netowork) 인프라스트럭처가 구축된 환경에서 무선 장비만을 이용하여 위치를 측정하는 방법들이 연구되고 있다. 이미 위치가 알려지고 고정된 AP(Access Point)와 노드간의 RSSI(Received Signal Strength Indicator)만을 이용하는 비콘 기반의 위치 측정 시스템 보다 무선 장비들 간의 RSSI 까지도 이용하는 상호 협력 위치 측정 시스템(Cooperative Positioning System)은 정확성이 높기 때문에 많은 관심을 끌고 있다. 본 논문에서는 상호 협력 위치 측정 시스템 중의 하나인 기존의 WiPS(wireless LAM based indoor Positioning System)의 문제점을 분석하고, 이웃하는 노드간의 영향 관계를 밝히고, 노드의 밀도에 따라 위치 수렴 조정 계수를 결정하여 성능을 개선한 WiCOPS-d(Wireless Cooperative Positioning System using node density)를 제안한다.

• Experimental Neurobiology
• /
• 제26권5호
• /
• pp.241-251
• /
• 2017

Saturation mutagenesis was performed on a single position in the voltage-sensing domain (VSD) of a genetically encoded voltage indicator (GEVI). The VSD consists of four transmembrane helixes designated S1-S4. The V220 position located near the plasma membrane/extracellular interface had previously been shown to affect the voltage range of the optical signal. Introduction of polar amino acids at this position reduced the voltage-dependent optical signal of the GEVI. Negatively charged amino acids slightly reduced the optical signal by 33 percent while positively charge amino acids at this position reduced the optical signal by 80%. Surprisingly, the range of V220D was similar to that of V220K with shifted optical responses towards negative potentials. In contrast, the V220E mutant mirrored the responses of the V220R mutation suggesting that the length of the side chain plays in role in determining the voltage range of the GEVI. Charged mutations at the 219 position all behaved similarly slightly shifting the optical response to more negative potentials. Charged mutations to the 221 position behaved erratically suggesting interactions with the plasma membrane and/or other amino acids in the VSD. Introduction of bulky amino acids at the V220 position increased the range of the optical response to include hyperpolarizing signals. Combining The V220W mutant with the R217Q mutation resulted in a probe that reduced the depolarizing signal and enhanced the hyperpolarizing signal which may lead to GEVIs that only report neuronal inhibition.

• Journal of Trauma and Injury
• /
• 제35권3호
• /
• pp.189-194
• /
• 2022

Purpose: The purpose of this study was to determine whether a higher Injury Severity Score (ISS) could serve as an indicator of splenectomy in patients with traumatic splenic lacerations. Methods: A total of 256 cases of splenic laceration were collected from January 1, 2005 to December 31, 2018. After the application of exclusion criteria, 105 were eligible for this study. Charts were reviewed for demographic characteristics, initial vital signs upon presentation to the emergency room, Glasgow Coma Scale, computed tomography findings, ISS, and treatment strategies. The cases were then divided into nonsplenectomy and splenectomy groups for analysis. Results: When analyzed with the chi-square test and t-test, splenectomy was associated with a systolic blood pressure lower than 90 mmHg, a Glasgow Coma Scale score lower than 13, active bleeding found on computed tomography, a splenic laceration grade greater than or equal to 4, and an ISS greater than 15 at presentation. However, in multivariate logistic regression analysis, only active bleeding on computed tomography showed a statistically significant relationship (P=0.014). Conclusions: Although ISS failed to show a statistically significant independent relationship with splenectomy, it may still play a supplementary role in traumatic splenic injury management.