• Asian Pacific Journal of Cancer Prevention
• /
• 제15권24호
• /
• pp.10813-10817
• /
• 2015

Background: Possible roles of nestin expression in terms of predicting intravesical BCG therapy response in T1 high grade bladder cancer patients were investigated. Materials and Methods: T1 high grade bladder cancer patients who were treated with intravesical BCG between 1990-2009 were included. Immunohistochemical staining for nestin expression was performed. Nestin(+) and nestin(-) patients were compared in terms of recurrence and progression rates. Results: Sixty-three patients were included and median follow-up time was twenty-five months. After staining; 33 patients (52.4%) were classified as nestin (+) and 30 (47.6%) as (-). Nestin (+) patients were more likely to recur compared to nestin (-) patients (60.6% vs. 30%, p<0.05). Progression rates were also higher in nestin (+) patients, although this result did not reach statistical significance (15.2 % vs. 10 %, p=0.710). Conclusions: Nestin expression, which seems effective in predicting recurrence, appears to have a potential role in the urothelial carcinoma tumorigenesis. Patients with high grade bladder cancer and positive nestin expression need close follow-up and might be informed about more tendency to recur. Further comprehensive studies including larger patient cohorts may clarify the role of nestin in bladder cancer.

• Korean Journal of Acupuncture
• /
• 제19권2호
• /
• pp.149-165
• /
• 2002

Objective : We proposed fundmental rules of prospective on legal and institutional position and role of Korean medicine doctors working at public health center. Methods : By the result of this research on the current situation, the grade and allowance given to the Korean medicine doctors working at public health center were different every self-governing body. Results : The reason the Korean Medicine Doctor can't serve as a regular order of 5th grade is that the 'The Enforcement Regulation about Administrative Organization and the Standard of Pixed Number of person of Self-Governing Body(지방자치단체의 행정기구와 정원기준등에 관한 규정 시행규칙)' prescribes the number of regular order of 5th grade is regulated within 7% among the number of regular order officials. But not appointing to office as the regular order of 5th grade infringes on the Constitution, the highest law. The reason the Korean Medicine Doctors can't be appointed to office as the regular order officials by the self-governing body is that 'The Enforcement Order of the Law of Preservation of good health of Local Area(지역보건법시행령)' prescribes the Korean Medicine Doctors are not indispensable to Public Health Center. But in fact, the Korean Medicine Doctors can execute many kinds of work such as medical examination or instructing house nursing. Conclusion : The Korean Medicine Doctors working at Public Health Center serve at low positions as daily use or common use, not receiving a regular order. All laws including the Constitution(헌법), the Medical Services Law(의료법), the Law of Preservation of good health of Local Area(지역보건법), the National Public Service Law(국가공무원법), the Local Public Service Law(지방공무원법) and the Law of Higher Education Law(고등교육법) describe that the Korean Medicine Doctors and the Western Medicine Doctors are equal to their position and right.

• Journal of Korean Neurosurgical Society
• /
• 제48권6호
• /
• pp.480-484
• /
• 2010

Objective : To evaluate the role of lumbar drainage in the prevention of shunt-dependent hydrocephalus after treatment of ruptured intracranial aneurysms by coil embolization in good-grade patients. Methods : One-hundred-thirty consecutive patients with aneurysmal subarachnoid hemorrhage in good-grade patients (Hunt & Hess grades I-III), who were treated by coil embolization between August 2004 and April 2010 were retrospectively evaluated. Poor-grade patients (Hunt & Hess grades IV and V), a history of head trauma preceding the development of headache, negative angiograms, primary subarachnoid hemorrhage (SAH), and loss to follow-up were excluded from the study. We assessed the effects on lumbar drainage on the risk of shunt-dependent hydrocephalus related to coil embolization in patients with ruptured intracranial aneurysms. Results : One-hundred-twenty-six patients (96.9%) did not develop shunt-dependent hydrocephalus. The 2 patients (1.5%) who developed acute hydrocephalus treated with temporary external ventricular drainage did not require permanent shunt diversion. Overall, 4 patients (3.1%) required permanent shunt diversion; acute hydrocephalus developed in 2 patients (50%). There was no morbidity or mortality amongst the patients who underwent a permanent shunt procedure. Conclusion : Coil embolization of ruptured intracranial aneurysms may be associated with a lower risk for developing shunt-dependent hydrocephalus, possibly by active management of lumbar drainage, which may reflect less damage for cisternal anatomy than surgical clipping. Coil embolization might have an effect the long-term outcome and decision-making for ruptured intracranial aneurysms.

• Journal of Korean Neurosurgical Society
• /
• 제60권1호
• /
• pp.15-20
• /
• 2017

Objective : Diagnosing tumor progression and pseudoprogression remains challenging for many clinicians. Accurate recognition of these findings remains paramount given necessity of prompt treatment. However, no consensus has been reached on the optimal technique to discriminate tumor progression. We sought to investigate the role of magnetic resonance perfusion (MRP) to evaluate tumor progression in glioma patients. Methods : An institutional retrospective review of glioma patients undergoing MRP with concurrent clinical follow up visit was performed. MRP was evaluated in its ability to predict tumor progression, defined clinically or radiographically, at concurrent clinical visit and at follow up visit. The data was then analyzed based on glioma grade and subtype. Resusts : A total of 337 scans and associated clinical visits were reviewed from 64 patients. Sensitivity, specificity, positive and negative predictive value were reported for each tumor subtype and grade. The sensitivity and specificity for high-grade glioma were 60.8% and 87.8% respectively, compared to low-grade glioma which were 85.7% and 89.0% respectively. The value of MRP to assess future tumor progression within 90 days was 46.9% (sensitivity) and 85.0% (specificity). Conclusion : Based on our retrospective review, we concluded that adjunct imaging modalities such as MRP are necessary to help diagnose clinical disease progression. However, there is no clear role for stand-alone surveillance MRP imaging in glioma patients especially to predict future tumor progression. It is best used as an adjunctive measure in patients in whom progression is suspected either clinically or radiographically.

• 한국학교수학회논문집
• /
• 제11권2호
• /
• pp.177-199
• /
• 2008

Streefland(Elbers, 2003)는 네덜란드에서 11세에서 13세 사이의 초등학생들을 대상으로 하는 탐구-집단(community of inquiry)의 구성과 활동에 관한 연구를 통하여 지식을 구성하는 과정에 학생들이 참여할 수 있도록 교사가 도울 수 있는 방법에 대한 해결책을 제시하고자 했다. Goos(2004)는 오스트레일리아의 고등학교 3학년 수학교실에서는 당연한 것으로 여겨진 탐구 문화를 고등학교 2학년 교실에서 교사가 어떻게 형성시키는지를 관찰과 인터뷰를 통하여 분석하였다. 한국에서는 대학입시 제도를 포함한 다양한 문제점들로 인하여 고등학교 학생들을 대상으로 하는 탐구-중심 수업에서 교사의 역할과 관련된 체계적인 연구는 거의 없었다. 본 연구에서는 과학고등학교 학생들을 대상으로 하는 탐구-중심 수업의 활성화를 위한 교사의 역할에 대하여 논의 하고자 한다. 이를 위하여 탐구-중심 수업 모델을 개발하고, 개발된 탐구-중심 수업 모델을 바탕으로 소집단별로 문제를 선정하고 해결하면서 학생 스스로 수학적인 활동을 할 수 있도록 안내하는 조력자로서의 교사의 역할에 관하여 탐색한다.

• 한국초등과학교육학회지:초등과학교육
• /
• 제24권2호
• /
• pp.138-144
• /
• 2005

This study was intended to survey and analyze the illustrations of the elementary science textbooks in the』 7th revised education curriculum in Korea, and to compare the results with the illustration organization of the elementary science textbooks of Japan. The analysis criterion was composed of two categories, the kind of illustration and the role of illustration. The kind of illustration was divided into five subcategories such as photograph, picture, illustration, cartoon and diagram. The role of illustration was divided into four subcategories such as motive induction, guidance for learning, the supply of material, the presentation of results. According to the analyzing criterion, the frequencies of relevant subcategories of illustrations in science textbooks were checked and arranged and the resultant data were analyzed by grades. The findings of this study were as follows: 1. Korean science textbooks have about 3.29 illustrations per page whereas Japanese ones have 4.1l. Compared with Korean science textbooks, Japanese ones have more illustrations. 2. From the analysis of the kinds of the illustrations by grade basis, it was found that the order of percentage of illustrations is photograph, cartoon and picture in both countrys' science textbooks. Korean ones are highly dependent on photograph. As a contrast Japanese ones have more ratio of cartoon and picture than Korean science textbooks. 3. The analysis of the roles of the illustrations by grade basis showed that the role of guidance for learning is major in both countrys' science textbooks. The role of guidance for learning is prominent in Japanese ones, but in Korean ones, the role of guidance for learning is a little higher than that of the supply of material.

• 가정과삶의질연구
• /
• 제7권2호
• /
• pp.45-60
• /
• 1989

The present study analyzed data from 417 grandchildren in the fifth grade of the elementary school with regard to patterns of contact and the content and the level of grandmothers role performance. Major findings were as follows; 1) The most frequent of association occuring between grandmothers and grandchildren was telephoning, next visiting and writing. The mothers, attitude and geographical proximity were consistently related to the level of the contact between grandmothers and grandchildren. 2) The family type, the attitude of the mothers and the health condition of grandmothers were related to the level of the grandmothers role performance. The role of the grandmothers consists with six dimensions of discipliner, surrogate parenting, interference, historical and sex role adviser, confidant and material provider.

• 간호행정학회지
• /
• 제11권2호
• /
• pp.119-127
• /
• 2005

Purpose: The Purpose of this study was to identify the relationship between self-disclosure and role conflict in nursing students. Method: The subjects were 386 nursing students who were in college and university. The data were collected from July 26 to September 18, 2004 by the structured questionnaires. For data analysis, descriptive statistics, Pearson correlation coefficient, and ANOVA & t-test with SAS package were used. Results: 1. The mean of self-disclosure perceived by nursing students was 3.57(${\pm}$.53), and the mean of role conflict perceived by nursing students was 3.62(${\pm}$.49). If the role conflict was divided into subcategory, deficiency of ability and skill was 3.77(${\pm}$.60), role ambiguity was 3.66(${\pm}$.54), and internal conflict was 3.49(${\pm}$.62). 2. 'Role conflict', 'deficiency of ability and skill', 'role ambiguity' and 'internal conflict' were positively related to 'self-disclosure'. 3. 'Self-disclosure' showed a significant difference according to interpersonal relations, meaning on nursing job and 'role conflict' showed a significant difference according to school career, present grade. Conclusion: this study suggested that there are need to implement self-disclosure training program for nursing student to decrease role conflict.

• 한국수학교육학회지시리즈D:수학교육연구
• /
• 제16권2호
• /
• pp.91-106
• /
• 2012

Spatial ability has been valued as a talent domain and important skill in mathematics education because it enhanced an intuitive view and an understanding in many areas of mathematic. In addition, spatial ability highly correlates with mathematics achievement, indicating its crucial role in success in mathematics education. Some researchers founded gender differences in mathematics and spatial ability, and indicated that spatial ability served as a mediator of gender difference in mathematics. This study explored the spatial ability of 349 Korean middle school students (Grade 7-9), and investigated the association among students' spatial ability and their mathematics achievement, gender, and grade. The result of this study shows that spatial ability correlates positively with mathematics achievement. While gender difference did not exist in mathematics, significant gender difference existed in spatial ability favoring male students.

• 한국지능정보시스템학회:학술대회논문집
• /
• 한국지능정보시스템학회 2001년도 The Pacific Aisan Confrence On Intelligent Systems 2001
• /
• pp.237-245
• /
• 2001

Automated essay grading has been proposed for over thirty years. Only recently have practical implementations been constructed and tested. This paper investigated the role of the nearest-neighbour algorithm within the information retrieval as a way of grading the essay automatically called Automated Essay Grading System. It intended to offer teachers an individualized assistance in grading the student\`s essay. The system involved several processes, which are the indexing, the structuring of the model answer and the grade processing. The indexing process comprised the document indexing and query processing which are mainly used for representing the documents and the query. Structuring the model answer is actually preparing the marking scheme and the grade processing is the process of assessing the essay. To test the effectiveness of the developed algorithms, the algorithms are tested against the History text in Malay. The result showed that th information retrieval and the nearest-neighbour algorithm are practical combination that offer acceptable performance for grading the essay.