• 대한간호학회지
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• 제41권5호
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• pp.663-672
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• 2011

Purpose: Purpose of this study was to investigate the status of depression in academic high school students and path analysis model for exploring the mediating role of entrapment to depression in relation to academic stress and perceived social support. Methods: Measurements were four reliable questionnaires measuring academic stress, social support, entrapment, and depression. Data were collected from students in 17 high schools in Seoul. Results: Students (n=5,346) completing the questionnaires indicated depression & entrapment from academic stress. Depression was more prevalent in girls, those whose parents' household income was less than two million won, who did not live with father or mother or both due to divorce, separation, or death, and those who smoked or used alcohol. Entrapment was more prevalent in students similar to cases of depression and in seniors. According to the proposed path model, 48.6% of depression was explained by academic stress, social support, and entrapment. The indirect effect of entrapment as a mediator between academic stress and depression was verified and larger than the direct effect of academic stress on depression. Conclusion: Considering levels of depression and entrapment demonstrated by these students, better mental health programs with diverse strategies should be developed for their psychological well-being.

• Journal of Pharmaceutical Investigation
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• 제29권4호
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• pp.315-321
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• 1999

Poly (lactide-co-glycolide) (PLGA) microspheres containing ovalbumin (OVA) as a model protein drug were prepared by double emulsification method, and various conditions such as mixing rate, volume of outer phase and isopropyl alcohol concentration in outer phase during secondary emulsification were observed to control the size of microspheres. In addition, entrapment efficiency of OVA and protein denaturation were also evaluated. As the rate of stirring was increased, the size of particles was decreased. But excessive stirring increased the particle size of microspheres. In a preparation condition of small volume of outer phase, the particle size was decreased but the entrapment efficiency was increased. Adding isopropyl alcohol to outer phase decreased the size of particles, but increased the entrapment efficiency. Microparticles should have smaller size than $10\;{\mu}m$ to be uptaked by Peyer's patch in small intestine. High speed of mixing and relatively small volume of outer phase are needed to reduce the size. In addition, appropriate amount of isopropyl alcohol in outer phase also plays an important role in size reduction of PLGA microspheres.

• Journal of Korean Neurosurgical Society
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• 제47권1호
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• pp.1-6
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• 2010

Objective: On the basis of preoperative computed tomography (CT) scans, we studied the change of the size of anterior primary division (APD) of the L5 spinal root in the presence of foraminal/extraforaminal entrapment of the L5 spinal root. Methods: Two independent radiologists retrospectively reviewed the preoperative CT scans of 27 patients treated surgically and compared the sizes of the APDs on bilateral L5 spinal roots. If one side APO size was larger than the other side APD size, it was described as left or right "dominancy" and regarded this as "consensus (C)" in case that there was a consensus between the larger APD and the location of sciatica, and regarded as "non-consensus (NC)" in case that there was not a consensus. Oswestry Disability Index (ODI) scores were used for preoperative and postoperative evaluation. Results: On CT scans, twenty-one (77%) of 27 patients were the consensus group (APD swelling) and 6 (22%) were a non-consensus group (APD no swelling). In 9 patients with acute foraminal disc herniations, asymmetric enlargement of the APD on L5 spinal root was detected in all cases (100%) and detected in 11 (64%) of 17 patients with stenosis. Preoperative ODI score was 75-93 (mean 83) and postoperative 001 scores were improved to 13-36 (mean 21). The mean follow-up period was 6 months (range, 3-11 months). Conclusion: An asymmetric enlargement of the APD on L5 spinal root on CT scans is meaningfully associated with a foraminal or extraforaminal entrapment of the L5 spinal root on the lumbosacral junction.

• Journal of Korean Neurosurgical Society
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• 제67권2호
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• pp.217-226
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• 2024

Objective : The efficacy of sciatic nerve decompression via transgluteal approach for entrapment of the sciatic nerve at the greater sciatic notch, called piriformis syndrome, and factors affecting the surgical outcome were analyzed. Methods : The outcome of pain reduction was analyzed in 81 patients with sciatic nerve entrapment who underwent decompression through a transgluteal approach. The patients were followed up for at least 6 months. The degree of pain reduction was analyzed using a numerical rating scale-11 (NRS-11) score and percent pain relief before and after last follow-up following surgery. Success was defined by at least 50% reduction in pain measured via NRS-11. To assess the degree of subjective satisfaction, a 10-point Likert scale was used. In addition, demographic characteristics, anatomical variations, and variations in surgical technique involving sacrotuberous ligamentectomy were analyzed as factors that affect the surgical outcome. Results : At a follow-up of 17.5±12.5 months, sciatic nerve decompression was successful in 50 of 81 patients (61.7%), and the pain relief rate was 43.9±34.17. Subjective improvement based on a 10-point Likert scale was 4.90±3.43. Among the factors that affect the surgical outcome, only additional division of the sacrotuberous ligament during piriformis muscle resection played a significant role. The success rate was higher in the scarotuberous ligementectomy group (79.4%) than in the non-resection group (42.6%), resulting in statistically significant difference based on average NRS-11 score, percent pain relief, and subjective improvement (p<0.05, independent t-test). Conclusion : Sciatic nerve decompression is effective in pain relief in chronic sciatica due to sciatic nerve entrapment at the greater sciatic notch. Its effect was further enhanced by circumferential dissection of the sciatic nerve based on the compartment formed by the piriformis muscle and the sacrotuberous ligament in the greater sciatic notch.

• 말소리와 음성과학
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• 제8권3호
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• pp.91-109
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• 2016

This study was mainly aimed to investigate on the perceptions of occupational suitability for speakers who stutter and the associated factors. 90 college students who do not stutter participated in this study and asked to hear one of three audio recordings(i.e., fluent version, mildly-stuttered version, and severely-stuttered version) of a male speaker who stuttered. Then, the participants were asked to rate the speaker's communicative functioning, personal attributes, and suitability for 31 occupations, along with perceptions of the occupations' speaking demands and educational requirements. Results show that speakers who stuttered (i.e., mildly-stuttered and severely-stuttered version) received lower suitability ratings for high speaking demand occupations than for low speaking demand occupations. In addition, it has been shown that perceived speaking demand strongly affected occupational suitability ratings at both levels of stuttering severity. However, it has been shown that occupational suitability ratings were not associated with ratings of the speaker's personal attributes and perceived educational requirements. From these findings it can be argued that adults who stutter may face occupational stereotyping and/or role entrapment in work settings.

• Annals of Clinical Neurophysiology
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• 제4권2호
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• pp.98-107
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• 2002

Multifocal motor neuropathy (MMN) is a chronic immune-mediated peripheral myelinopathy. The major clinical features include slowly progressive, painless, and asymmetric weakness, usually of distal limb muscle. Early in the course of the disease, weakness is not necessarily associated with muscle atrophy, owing to the initial primary involvement of peripheral myelin. Chronic progressive weakness is often associated with some degree of concurrent axonal loss and subsequent muscle atrophy. Sensory symptoms are usually mild or absent, and involvement of cranial and respiratory muscles is rare. The findings of multifocal motor conduction block, abnormal temporal dispersion, and focal conduction slowing at segments not at risk for common entrapment or compression injury, associated with normal sensory conduction studies along the same segments, are the hallmark electrophysiologic features of MMN. The slow progression and absence of upper motor neuron signs are the major clinical points that separate MMN from amyotrophic lateral sclerosis. The role of GM1 antibodies, found in high titers in 22~84% of MMN patients, remains uncertain. The contention that MMN is an autoimmune disorder is largely based on the often dramatic improvement in symptoms following the administration of intravenuos immunoglobulin or cyclophosphamide.

• 말소리와 음성과학
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• 제11권2호
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• pp.65-76
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• 2019

본 연구에서는 직업상담사를 대상으로 한국고용노동부에 수록된 31개의 직업군들을 바탕으로 말더듬 성인을 위한 직업 추천 양상에 대한 실증적 연구를 진행하였다. 총 69명의 직업상담사(실험조건 당 23명)로 하여금 말더듬 성인을 통해 생성된 세 가지 발화샘플(유창한 발화, 덜 심한 말더듬, 심한 말더듬) 중 하나를 듣고 제공된 척도질문지(직업 관련 말하기 요구량 척도, 직업 관련 교육 수준 척도, 직업 조언 척도, 의사소통 평정 척도, 의미 차이 평정 척도)를 통해 평가하였다. 실험 결과, 두 말더듬 상황에서 직업 관련 말하기 요구량이 높은 직업군은 낮게 추천한 반면, 직업 관련 말하기 요구량과 교육 수준 정도가 모두 낮은 직업군은 높게 추천되었다. 또한 의사소통 평정에 있어 실험조건 간 유의한 차이가 나타났지만, 의미 차이 평정에 있어서는 차이가 나타나지 않았다. 직업 추천 정도와 관련해 직업 관련 말하기 요구량 인식 정도는 유의한 수준에서 부적 상관관계가, 의사소통 평정은 유의한 수준에서 정적 상관관계가 나타났다. 또한, 의미 차이 평정에 있어서도 유의한 수준에서의 정적 상관관계가 나타났다. 이는 의사소통장애인으로서 말더듬 성인이 직업과 관련해 상당한 역할 제한성을 가지고 있음을 보여주는 결과라 할 수 있다.

• Journal of Yeungnam Medical Science
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• 제41권2호
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• pp.120-127
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• 2024

Background: Physiatrists are facing with survivors from disasters in both the acute and chronic phases of muscle and nerve injuries. Similar to many other clinical conditions, neuromusculoskeletal ultrasound can play a key role in the management of such cases (with various muscle/nerve injuries) as well. Accordingly, in this article, a recent single-center experience after the Turkey-Syria earthquake will be rendered. Methods: Ultrasound examinations were performed for various nerve/muscle lesions in 52 earthquake victims referred from different cities. Demographic features, type of injuries, and applied treatment procedures as well as detailed ultrasonographic findings are illustrated. Results: Of the 52 patients, 19 had incomplete peripheral nerve lesions of the brachial plexus (n=4), lumbosacral plexus (n=1), and upper and lower limbs (n=14). Conclusion: The ultrasonographic approach during disaster relief is paramount as regards subacute and chronic phases of rehabilitation. Considering technological advances (e.g., portable machines), the use of on-site ultrasound examination in the (very) early phases of disaster response also needs to be on the agenda of medical personnel.

• Journal of Yeungnam Medical Science
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• 제41권1호
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• pp.45-47
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• 2024

Peripheral nerves may be affected or injured for several reasons. Peripheral nerve damage can result from trauma, surgery, anatomical abnormalities, entrapment, systemic diseases, or iatrogenic injuries. Trauma and iatrogenic injuries are the most common causes. The ulnar, median, and radial nerves are the most injured nerves in the upper extremities, while the sciatic and peroneal nerves are the most injured nerves in the lower extremities. The clinical symptoms of peripheral nerve damage include pain, weakness, numbness/ tingling, and paresthesia. Therefore, early diagnosis and appropriate treatment of peripheral nerve injuries are crucial. If a peripheral nerve injury is left untreated, it can lead to severe complications and significant morbidity. The sciatic nerve is one of the most affected nerves. This nerve is generally injured by trauma and iatrogenic causes. Children are more susceptible to trauma than adults. Therefore, sciatic nerve injuries are observed in pediatric patients. When the sciatic nerve is damaged, pain, weakness, sensory loss, and gait disturbances can occur. Therefore, the diagnosis and treatment of sciatic nerve injuries are important to avoid unexpected consequences. Ultrasound can play an important role in the diagnosis of peripheral nerve injury and the follow-up of patients. The aim of this case report is twofold. First, we aimed to emphasize the critical role of ultrasonographic evaluation in the diagnosis of peripheral nerve injuries and pathologies. Second, we aimed to present this case, which has distinguishing features, such as the existence of periostitis ossificans progressiva with sciatic neurotmesis due to a traumatic glass injury.

• 한국경제지리학회지
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• 제14권3호
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• pp.437-451
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• 2011

본 연구에서는 서울의 인구집중 해소와 함께 자족기능을 갖춘 도시의 개발을 목적으로 수도권 1기 신도시 건설계획이 수립된 이후 20여년이 경과한 시점에서 그간 서울시 거주자의 통근통행패턴에 어떤 변화가 있었는지 살펴보았다. 우선 통근시간에 영향을 주는 요인을 판별하기 위해 가구통행실태조사 자료를 이용하여 다중회귀분석을 실시한 후, 초과통근 실태를 분석하여 서울시의 직주 불일치 정도를 알아보았다. 분석결과에 따르면, 통근자들은 소득이 높아질수록 통근시간이 늘어나다가 일정 수준에 다다르면 통근시간이 줄어드는 양상을 보였다. 또한 서울시의 통근비용이 최소화되는 경우에 비해 상당한 수준의 초과통근이 이루어지고 있는 것으로 나타났다. 전체적으로 서울의 직주 불일치가 과거에 비해 완화된 것으로 나타나나, 행정구별로는 여전히 직주 불일치도의 격차가 심하였다. 수도권 신도시 건설 이후 서울 거주자들의 통근패턴 변화와 현재의 직주불일치 정도를 파악한 본 연구 결과를 통해 비효율적 통근 문제의 해결책을 모색하고, 지속가능한 도시개발을 가능케 하는 정책이 수립될 수 있을 것이다.