• 제목/요약/키워드: risk-sensitive

검색결과 425건 처리시간 0.028초

소비자의 감각적 혁신성향과 인지적 혁신성향이 신제품 구매의도에 미치는 이중 경로 (Dual Path Impacts of the Consumer Innovativeness in the New Products Adoption Situation)

  • 김형준
    • 한국콘텐츠학회논문지
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    • 제11권8호
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    • pp.187-197
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    • 2011
  • 연구는 기존 연구들이 단일한 개념으로 인식하고 있던 혁신성향 개념을 인지적 혁신성향과 감각적 혁신성향으로 구분하고 두 유형의 혁신 성향의 정도에 따라 신제품에 대한 소비자의 지각된 위험의 민감성이 다름을 보였다. 이러한 지각된 위험의 유형과 수준의 차이는 각각의 혁신 성향이 소비자의 신제품 구매의도에 있어 서로 다른 영향력이 있음을 보여 줌으로써 혁신성향이 소비자의 신제품 구매의도에 미치는 경로가 이중경로임을 제시하였다. 217명을 대상으로 회귀분석과 공변량 구조 분석을 통하여 실증 분석을 수행한 결과 감각적 혁신성향 보다 인지적 혁신성향이 높을수록 사회적 위험보다 기능적 위험을 더 많이 지각하는 반면 감각적 혁신성향이 높을수록 기능적 위험보다는 사회적 위험을 더 지각하는 것으로 나타났다. 즉, 신제품 구매에 따른 기능적 위험 지각과 사회적 위험 지각이 소비자의 혁신성향의 유형에 따라 다르게 나타남을 제시하였다. 기존 연구에서는 소비자의 혁신성향 개념을 하나의 구성 개념으로 파악하여 신제품 구매의도에 대한 영향 관계를 파악하였으나 본 연구는 감각적 혁신성향과 인지적 혁신성향으로 소비자의 혁신성향을 구분하고 신제품 구매의도와의 관계를 파악하였으며 각각의 혁신성향이 신제품에 대해 인지하는 지각 위험의 경로를 달리함을 밝혔다.

인지된 위험의 유형이 소비자 신뢰 및 온라인 구매의도에 미치는 영향 (The Impact of Perceived Risks Upon Consumer Trust and Purchase Intentions)

  • 홍일유;김우성;임병하
    • Asia pacific journal of information systems
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    • 제21권4호
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    • pp.1-25
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    • 2011
  • Internet-based commerce has undergone an explosive growth over the past decade as consumers today find it more economical as well as more convenient to shop online. Nevertheless, the shift in the common mode of shopping from offline to online commerce has caused consumers to have worries over such issues as private information leakage, online fraud, discrepancy in product quality and grade, unsuccessful delivery, and so forth, Numerous studies have been undertaken to examine the role of perceived risk as a chief barrier to online purchases and to understand the theoretical relationships among perceived risk, trust and purchase intentions, However, most studies focus on empirically investigating the effects of trust on perceived risk, with little attention devoted to the effects of perceived risk on trust, While the influence trust has on perceived risk is worth studying, the influence in the opposite direction is equally important, enabling insights into the potential of perceived risk as a prohibitor of trust, According to Pavlou (2003), the primary source of the perceived risk is either the technological uncertainty of the Internet environment or the behavioral uncertainty of the transaction partner. Due to such types of uncertainty, an increase in the worries over the perceived risk may negatively affect trust, For example, if a consumer who sends sensitive transaction data over Internet is concerned that his or her private information may leak out because of the lack of security, trust may decrease (Olivero and Lunt, 2004), By the same token, if the consumer feels that the online merchant has the potential to profit by behaving in an opportunistic manner taking advantage of the remote, impersonal nature of online commerce, then it is unlikely that the merchant will be trusted, That is, the more the probable danger is likely to occur, the less trust and the greater need to control the transaction (Olivero and Lunt, 2004), In summary, a review of the related studies indicates that while some researchers looked at the influence of overall perceived risk on trust level, not much attention has been given to the effects of different types of perceived risk, In this context the present research aims at addressing the need to study how trust is affected by different types of perceived risk, We classified perceived risk into six different types based on the literature, and empirically analyzed the impact of each type of perceived risk upon consumer trust in an online merchant and further its impact upon purchase intentions. To meet our research objectives, we developed a conceptual model depicting the nomological structure of the relationships among our research variables, and also formulated a total of seven hypotheses. The model and hypotheses were tested using an empirical analysis based on a questionnaire survey of 206 college students. The reliability was evaluated via Cronbach's alphas, the minimum of which was found to be 0.73, and therefore the questionnaire items are all deemed reliable. In addition, the results of confirmatory factor analysis (CFA) designed to check the validity of the measurement model indicate that the convergent, discriminate, and nomological validities of the model are all acceptable. The structural equation modeling analysis to test the hypotheses yielded the following results. Of the first six hypotheses (H1-1 through H1-6) designed to examine the relationships between each risk type and trust, three hypotheses including H1-1 (performance risk ${\rightarrow}$ trust), H1-2 (psychological risk ${\rightarrow}$ trust) and H1-5 (online payment risk ${\rightarrow}$ trust) were supported with path coefficients of -0.30, -0.27 and -0.16 respectively. Finally, H2 (trust ${\rightarrow}$ purchase intentions) was supported with relatively high path coefficients of 0.73. Results of the empirical study offer the following findings and implications. First. it was found that it was performance risk, psychological risk and online payment risk that have a statistically significant influence upon consumer trust in an online merchant. It implies that a consumer may find an online merchant untrustworthy if either the product quality or the product grade does not match his or her expectations. For that reason, online merchants including digital storefronts and e-marketplaces are suggested to pursue a strategy focusing on identifying the target customers and offering products that they feel best meet performance and psychological needs of those customers. Thus, they should do their best to make it widely known that their products are of as good quality and grade as those purchased from offline department stores. In addition, it may be inferred that today's online consumers remain concerned about the security of the online commerce environment due to the repeated occurrences of hacking or private information leakage. Online merchants should take steps to remove potential vulnerabilities and provide online notices to emphasize that their website is secure. Second, consumer's overall trust was found to have a statistically significant influence on purchase intentions. This finding, which is consistent with the results of numerous prior studies, suggests that increased sales will become a reality only with enhanced consumer trust.

다제내성 폐결핵 치료실패의 위험인자 분석 (The Analysis of Risk Factors of Treatment Failure in MDR-TB)

  • 김형수;최광민
    • Tuberculosis and Respiratory Diseases
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    • 제50권6호
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    • pp.686-692
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    • 2001
  • 배 경 : 다제내성 폐결핵의 발생은 약제선택의 제한성과장기간의 항결핵제의 복용으로 인한 부작용 등으로 인하여 치료 성공율을 감소시킨다. 본 연구는 치료 실패인자들을 알아내어 다제내성 폐결핵의 치료 성공율을 향상시키는데 기초자료로 삼고자 하였다. 대상 및 방법 : 1996년 1월부터 1998년 12월까지 입원치료를 시행한 다제내성 폐결핵 환자 111명을 대상으로 하였다. 다제내성 폐결핵 치료의 실패에 관계되는 인자들을 분석하기 위하여 치료에 성공한 군(I군)과 실패한 군(II군)으로 나누어 각 인자들을 독립표본 T-검정, $X^2$ 검정 그리고 Fisher의 정확확률 검정으로 비교 분석하였다. 결 과 : I군과 II군을 비교한 결과, 폐결핵 과거력의 유무, 흉부방사선 검사상 공동이 있는 경우와 과거의 치료 횟수, 내성 약제의 개수 그리고 치료약제의 개수에서 통계적 유의성을 관찰할 수 있었다(p<0.05). 결 론 : 다제내성 폐결핵 치료 실패의 위험인자는 과거의 치료력, 흉부방사선상 공동이 있는 경우, 내성약제의 개수가 많은 것임을 알 수 있었다. 따라서 다제내성 폐결핵의 치료 효과를 향상시키기 위하여 초치료 폐결핵관리를 보다 철저히 하여 항결핵제에 대한 약제 내성발생을 억제하는데 노력을 하여야 할 것으로 생각된다.

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Optimization of the 32P-postlabeling Assay for Detecting Benzo(a)pyrene-induced DNA Adduct Formation in Zacco platypus

  • Lee, Jin Wuk;Lee, Sung Kyu
    • 한국환경보건학회지
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    • 제40권1호
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    • pp.55-62
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    • 2014
  • Objectives: $^{32}P$-postlabeling assay is the most sensitive method of detecting DNA adduct formation. However, it is limited by a low sample throughput and use of radioisotopes (RI). In this study, we modified it to minimize these limitations and applied it to Z. platypus exposed to Benzo(a)pyrene (BaP) in order to investigate DNA adduct formation (effect biomarker for pollutants) in Z. platypus for assessing risk of waterborne BaP exposure. Methods: DNA hydrolysis was performed only with Micrococcal nuclease (MNase), RI reduction test was performed and the overlapping steps between thin layer chromatography (TLC) and radioisotope high-performance liquid chromatography (RI-HPLC) were omitted. The application of a modified method to Z. platypus exposed to BaP was performed. Results: The results revealed that the amount of RIs used can be reduced roughly 10-fold. Because the analysis time was shortened by 8.5 hours, the sample throughput per hour was increased compared with the previous method. The results of applying modified $^{32}P$-postlabeling assay to Z. platypus, DNA adduct formation in Z. platypus showed dose-dependency with the BaP concentration. Only BPDE-dGMP was detected as a DNA adduct. Conclusion: These results demonstrate that the modified $^{32}P$-postlabeling assay is a suitable method for detecting DNA adduct formation in Z. platypus exposed to waterborne BaP and will be useful in risk assessment of carcinogenic effect in aquatic environment due to BaP.

환자교차 설계 방법을 적용한 소아천식 입원에 대한 도시 대기오염의 급성영향평가 (Associations between Air Pollution and Asthma-related Hospital Admissions in Children in Seoul, Korea: A Case-crossover Study)

  • 이종태
    • Journal of Preventive Medicine and Public Health
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    • 제36권1호
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    • pp.47-53
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    • 2003
  • Objectives : I used a case-crossover design to investigate the association between air pollution, and hospital admissions for asthmatic children under the age of 15 years in Seoul, Korea Methods : I estimated the changes in the levels of hospitalization risk from theinterquartile (IQR) increase in each pollutant concentrations, using conditional logistic regression analyses, with controls for weather information. Results : Using bidirectional control sampling, the results from a conditional logistic regression model, with controls for weather conditions, showed the estimated relative risk of hospitalization for asthma among children to be 1.04 (95% confidence interval (CI), 1.01-1.08) for particulate matter with an aerodynamic diameter less than or equal to 10m (IQR=40.4ug/m3); 1.05 (95% CI, 1.00- 1.09) for nitrogen dioxide (IQR=14.6ppb): 1.02 (95% CI,0.97-1.06) for sulfur dioxide (IQR=4.4ppb): 1.03 (95% CI, 0.99-1.08) for ozone (IQR=21.7ppb): and 1.03 (95% CI, 0.99-1.08) for carbon monoxide f10R=1.0ppm). Conclusions : This empirical analysis indicates the bidirectional control sampling methods, by design, would successfully control the confounding factors due to the long-term time trends of air pollution. These findings also support the hypothesis that air pollution at levels below the current ambient air quality standards of Korea is harmful to sensitive subjects, such as asthmatic children.

위암 발생의 식이 및 관련요인에 대한 환자군-대조군 연구 (A Case -Control Study on Dietary and Other Factors Related to Stomach Cancer Incidence)

  • 염필영
    • Journal of Nutrition and Health
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    • 제31권1호
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    • pp.62-71
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    • 1998
  • As stomach cancer is very prevalent in Koreans, various factors, especially dietary factors, related to stomach cancer incidence were examined in a case-control study. The study population consisted of 105 individual s diagnosed for stomach cancer in two general hospitals and 124 control subjects, matched for age and sex, in Seoul. Data for general characteristics, family history, smoking and alcohol consumption, personality , dietary habits and food preference were obtained by self-administered questionnaire and personal interview. Heredity was found to be one of the most important factors causing stomach cancer. In addition, genetic inheritance tended to differ between the sexes. The male patients showed significantly higher incidence of their father's relatives than mother's relatives but the female patients showed higher incidence of their mother's relatives that father's relatives. Smoking was significantly related to stomach cancer. It was also found that the cases drank alcohol more frequently and in much greater quantity than the controls. Personality was related to the incidence of stomach cancer. The cases tended to be more sensitive , impatient, and anxious to do things quickly. With regards to dietary habits, the male cases had meals significantly more irregularly than the male controls. The relative risk of preferencefor salty food and ramen showed to be significantly very high. The male cases consumed carbonated beverages and instant foods, low intake of green yellow vegetables, smoking of cigarettes and drinking of alcohol may contribute to the risk of stomach cancer.

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Health Conditions Sensitive to Retirement and Job Loss Among Korean Middle-aged and Older Adults

  • Park, Su-San;Cho, Sung-Il;Jang, Soong-Nang
    • Journal of Preventive Medicine and Public Health
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    • 제45권3호
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    • pp.188-195
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    • 2012
  • Objectives: This study was conducted to examine the association between health condition and leaving the labor market among middle-aged and older adults in South Korea. Methods: Data was obtained from individuals aged 45 years and older participating in the 2006 and 2008 Korean Longitudinal Study of Ageing. We used various health measures including chronic diseases, comorbidities, traffic accident injuries, disabilit of instrumental activities of daily living, depressive symptoms, and self-rated health. The odds ratios of job loss, and retirement, versus employment were calculated using multinomial logistic regression by each health measure. Results: In our cross-sectional and longitudinal analysis, health problems related to physical disabilities had the greatest effect on leaving the worksite. A shift in health condition from good to poor in a short period was a predictor of increased risk of unemployment but a persistent pattern of health problems was not associated with unemployment. Women with health problems showed a high probability of retirement, whereas among men, health problems instantly the possibility of both job loss and retirement. Conclusions: Health problems of middle aged and older workers were crucial risk factors for retirement and involuntarily job loss. Especially functional defect and recent health problems strongly and instanty affected employment status.

PAX1 Methylation Analysis by MS-HRM is Useful in Triage of High-grade Squamous Intraepithelial Lesions

  • Wang, Zhen-Ming
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권2호
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    • pp.891-894
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    • 2014
  • This study is aimed to investigate the role of paired boxed gene 1 (PAX1) methylation analysis by methylation-sensitive high-resolution melting (MS-HRM) in the detection of high grade lesions in atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion (ASC-H) and compared its performance with the Hybrid Capture 2 (HC2) human papillomavirus (HPV) test. In our study, 130 cases with a diagnosis of ASC-H from the cervical cytological screening by Thinprep cytologic test (TCT) technique were selected for triage. Their cervical scrapings were collected and evaluated by using PAX1 methylation analysis (MS-HRM) and high-risk HPV DNA test (HC2), followed by colposcopy and cervical biopsy. Chi-square test were used to test the differences of PAX1 methylation or HPV infection between groups. In the detection of CIN2+, the sensitivity, specificity, the PPV, NPV and the accuracy of PAX1 MS-HRM assay and high-risk HPV (HR-HPV) tests were respectively 80.6% vs 67.7%, 94.9% vs 54.5%, 83.3%, vs 31.8%, 94.0% vs 84.4%, and 91.5% vs 57.7%. The PAX1 MS-HRM assay proved superior to HR-HPV testing in the detection of high grade lesions (CIN2+) in ASC-H. This approach could screen out the majority of high grade lesion cases of ASC-H, and thus could reduce the referral rate to colposcopy.

Bank-Specific Determinants of Loan Growth in Vietnam: Evidence from the CAMELS Approach

  • NGUYEN, Hoang Dieu Hien;DANG, Van Dan
    • The Journal of Asian Finance, Economics and Business
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    • 제7권9호
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    • pp.179-189
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    • 2020
  • The paper empirically examines the bank-specific determinants of loan growth in the Vietnamese banking system for the period from 2007 to 2019. We approach the CAMELS framework and employ the dynamic panel regression to determine the effects of each CAMELS factor on bank lending. To ensure the robustness of results, we also use alternative definitions of the variables and different specifications with and without full sets of CAMELS components. With these settings, we display multiple important results. (i) We find that a large capital buffer tends to boost bank lending expansion faster. (ii) High asset quality might positively contribute to high loan growth; in other words, banks subject to high credit risk are discouraged from making loans. (iii) Less efficiently managed banks are more likely to adopt an aggressive lending strategy, highlighting the moral hazard incentives of Vietnamese banks. (iv) More profitable banks with excellent competitive advantages could expand their lending activities to a larger extent. (v) Liquidity is positively related to the loan growth of banks. (vi) Perceived interest rate risk tends to suppress loan growth since interest-rate-sensitive banks might be concerned about the adverse effects of unpredictable adverse changes in interest rates in the future.

Addressing Early Life Sensitivity Using Physiologically Based Pharmacokinetic Modeling and In Vitro to In Vivo Extrapolation

  • Yoon, Miyoung;Clewell, Harvey J. III
    • Toxicological Research
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    • 제32권1호
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    • pp.15-20
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    • 2016
  • Physiologically based pharmacokinetic (PBPK) modeling can provide an effective way to utilize in vitro and in silico based information in modern risk assessment for children and other potentially sensitive populations. In this review, we describe the process of in vitro to in vivo extrapolation (IVIVE) to develop PBPK models for a chemical in different ages in order to predict the target tissue exposure at the age of concern in humans. We present our on-going studies on pyrethroids as a proof of concept to guide the readers through the IVIVE steps using the metabolism data collected either from age-specific liver donors or expressed enzymes in conjunction with enzyme ontogeny information to provide age-appropriate metabolism parameters in the PBPK model in the rat and human, respectively. The approach we present here is readily applicable to not just to other pyrethroids, but also to other environmental chemicals and drugs. Establishment of an in vitro and in silico-based evaluation strategy in conjunction with relevant exposure information in humans is of great importance in risk assessment for potentially vulnerable populations like early ages where the necessary information for decision making is limited.