• Title/Summary/Keyword: risk scoring

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Risk-based approach to develop a national residue program: prioritizing the residue control of veterinary drugs in fishery products

  • Kang, Hui-Seung;Han, Songyi;Cho, Byung-Hoon;Lee, Hunjoo
    • Fisheries and Aquatic Sciences
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    • v.22 no.12
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    • pp.29.1-29.7
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    • 2019
  • Veterinary drugs are widely used to protect production-related diseases and promote the growth of farmed fish. The use of large amounts of veterinary drugs may have potential risk and cause adverse effects on both humans and the environment. In this study, we developed risk-based ranking based on a scoring system to be applied in the national residue program. In this approach, the following three factors of veterinary drugs that may occur as residues in fishery products were considered: potency (acceptable daily intake), usage (number of dose and withdrawal period), and residue occurrence. The overall ranking score was calculated using the following equation: potency × usage (sum of the number of sales and withdrawal period) × residue occurrence. The veterinary drugs that were assigned high score by applying this approach were enrofloxacin, amoxicillin, oxolinic acid, erythromycin, and trimethoprim. The risk-based approach for monitoring veterinary drugs can provide a reliable inspection priority in fishery products. The developed ranking system can be applied in web-based systems and residuemonitoring programs and to ensure safe management of fishery products in Korea.

Risk Factors for Acquisition of Methicillin-Resistant Staphylococcus aureus in a Neurosurgical Intensive Care Unit(NSICU): Case-Control Study (신경외과 중환자실에서의 MRSA 획득 위험요인 분석)

  • Shin Yong-Soon;Lim Nan-Young
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.12 no.3
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    • pp.395-403
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    • 2005
  • Purpose: Methicillin-resistant Staphylococcus aureus (MRSA) is a major nosocomial pathogen in the intensive care units (ICUS). The purpose of this case-control study is to identify risk factors for acquisition of MRSA during ICU stays in patients with and without MRSA. Method: The study was conducted in a 16 beds-neurosurgical intensive care unit of a 2200-bed tertiary care university hospital in Seoul, Korea. Medical record and Critical Classification Scoring System were reviewed retrospectively in patients who were admitted more than 3 days from August 1, 2003 to May 30, 2004. Cases and controls were matched for age and gender. The obtained specimens were nasal swab and sputum. Result: There were 950 patients' admissions during the period. Among them, MRSA was isolated from twenty-three patients who were considered as hospital acquired. Artificial airway (p=.045), frequency of suction (p=.002), nasogastric tube (p=.004), wound drain (p=.045), and vancomycin (p=.019) were risk factors for MRSA acquisition in univariate analysis. Frequency of suction (p=.012, OR 3.5) was revealed as the only risk factor in multivariate conditional logistic regression. Conclusion: Our findings give support to recent studies that suggest that frequent physical contact maγ increase the nosocomial acquisition of MRSA in a neurosurgical ICU.

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An Evaluation Models for R&D Projects Selection (연구개발과제 선정을 위한 단계별 평가모형)

  • 이상철;하정진;김성희
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.17 no.31
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    • pp.73-80
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    • 1994
  • Sequentiality in decision making is an inherent characteristic of the R&D Process, Conceptual changes are noted during the Course of the Project which represent a continuous improvement in the quality of the data available during the various project stages. In this paper, Eight characteristic types of project evaluation models have been developed economic index models, portfolio models, decision theory models, risk analysis models, frontier models, scoring models, profile models and checklists. Each of these will be critically reviewed and appraised.

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-Reliability Assessment of Nuclear Power Plants Considering the Qualitative Factors under Uncertainty- (원자력발전소에서 정성적 요인을 고려한 신뢰성 평가)

  • 강영식
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.23 no.54
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    • pp.167-177
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    • 2000
  • The problem of system reliability is very important issue in the nuclear power plant, because the failure of its system brings about extravagant economic loss, environment destruction, and quality loss. This paper therefore proposes a normalized scoring model by the qualitative factors order to evaluate the robust reliability of nuclear power plants under uncertainty. Especially, the qualitative factors including risk, functional, human error, and quality function factors for the robust justification has been also introduced. Finally, the analytical reliability and safety assessment model developed in this paper can be used in the real nuclear power plant.

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Dynamic risk assessment of water inrush in tunnelling and software development

  • Li, L.P.;Lei, T.;Li, S.C.;Xu, Z.H.;Xue, Y.G.;Shi, S.S.
    • Geomechanics and Engineering
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    • v.9 no.1
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    • pp.57-81
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    • 2015
  • Water inrush and mud outburst always restricts the tunnel constructions in mountain area, which becomes a major geological barrier against the development of underground engineering. In view of the complex disaster-causing mechanism and difficult quantitative predictions of water inrush and mud outburst, several theoretical methods are adopted to realize dynamic assessment of water inrush in the progressive process of tunnel construction. Concerning both the geological condition and construction situation, eleven risk factors are quantitatively described and an assessment system is developed to evaluate the water inrush risk. In the static assessment, the weights of eight risk factors about the geological condition are determined using Analytic Hierarchy Process (AHP). Each factor is scored by experts and the synthesis scores are weighted. The risk level is ultimately determined based on the scoring outcome which is derived from the sum of products of weights and comprehensive scores. In the secondary assessment, the eight risk factors in static assessment and three factors about construction situation are quantitatively analyzed using fuzzy evaluation method. Subordinate levels and weight of factors are prepared and then used to calculate the comprehensive subordinate degree and risk level. In the dynamic assessment, the classical field of the eleven risk factors is normalized by using the extension evaluation method. From the input of the matter-element, weights of risk factors are determined and correlation analysis is carried out to determine the risk level. This system has been applied to the dynamic assessment of water inrush during construction of the Yuanliangshan tunnel of Yuhuai Railway. The assessment results are consistent with the actual excavation, which verifies the rationality and feasibility of the software. The developed system is believed capable to be back-up and applied for risk assessment of water inrush in the underground engineering construction.

Human Health Risk based Priority Ranking for Hazardous Air Pollutants (대기중 유해 화학 물질의 인체 위해도 우선순위 선정 연구)

  • Park Hoa-sung;Kim Ye-shin;Lee Dong-soo;Shin Dong-chun
    • Environmental Analysis Health and Toxicology
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    • v.19 no.1
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    • pp.81-91
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    • 2004
  • Although it is suggested that risk -based management plan is needed to manage air pollution effectively, we have no resources enough to evaluate all aspects of substances and set priorities. So we need to develop a logical and easy risk-based priority setting method. However, it if impossible that only one generic system that is consistent with all the use is developed. In this study, we proposed a human health risk based priority-setting method for hazardous air pollutants, and ranked priorities for this method. First of all, after investigating previous chemical ranking and scoring systems, we chose appropriate indicators and logics to goal of this study and made a chemical priority ranking method using these. As results, final scores in priority ranking method were derived for 25 substances, and ethylene oxide, acrylonitrile and vinyl chloride were included in high ranks. In addition, same substances were highly ranked when using default values like when using no default, but the scores of hydrofluoric acid and ryan and compounds were sensitive to default values. This study could be important that priorities were set including toxicity type and quality and local inherent exposure conditions and we can set area-specific management guidelines and survey plans as a screening tool.

Development of a Landslide Hazard Prediction Model using GIS (GIS를 이용한 산사태 위험지 판정 모델의 개발)

  • Lee, Seung-Kii;Lee, Byung-Doo;Chung, Joo-Sang
    • Journal of the Korean Association of Geographic Information Studies
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    • v.8 no.4
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    • pp.81-90
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    • 2005
  • Based on the landslide hazard scoring system of Korea Forest Research Institute, a GIS model for predicting landslide hazards was developed. The risk of landslide hazards was analyzed as the function of 7 environmental site factors for the terrain, vegetation, and geological characteristics of the corresponding forest stand sites. Among the environmental factors, slope distance, relative height and shapes of slopes were interpreted using the forestland slope interpretation module developed by Chung et al. (2002). The program consists of three modules for managing spatial data, analyzing landslide hazard and report-writing, A performance test of the model showed that 72% of the total landslides in Youngin-Ansung landslides area took place in the highly vulnerable zones of grade 1 or 2 of the landslide hazard scoring map.

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International Scoring System in Symptomatic Multiple Myeloma: Experience from a Tertiary Care Center

  • Sultan, Sadia;Irfan, Syed Mohammed;Parveen, Saira;Taufiq, Ufaq
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.4
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    • pp.2031-2033
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    • 2016
  • Background: Symptomatic multiple myeloma (MM) is an acquired B-cell malignant proliferation of antibody secreting plasma cells, characterized by end organ damage due to monoclonal immunoglobulin secretion. The aim of this study wa to determine the stage stratification according to an international scoring system in adult Pakistani MM patients at presentation. Materials and Methods: This single centre retrospective study extendedfrom January 2012 to December 2015. Data were retrieved from the departmental maintained records. Results: A total of 39 patients were diagnosed at our center with MM during the period of the study, 25 males and 14 females. Age ranged between 36 and 81 with a mean of $54.5{\pm}14.8$ and a median of 57 years. Common presenting complaints included fatigue (80.9%), backache (79.3%) and bone pain (66.2%). Overall, 9 patients were in ISS stage I (23%), 12 were in stage II (30.7%) and 18 were in stage III (46.1%). Out of the total, 29 (74.3%) had kappa immunoglobulin andthe remaining 10 (25.6%) had lambda type myelomas. IgG myeloma was commonest, seen in 26 (66.6%) followed by IgA in 11 (28.2%) with non secretory myeloma in one (2.5%) and light chain disease also in one patient (2.5%). Conclusions: MM in Pakistani patients is seen in a relatively young population with male predominance. Primarily patients are symptomatic and risk stratification revealed a predominance of advanced stage III disease in our setting.

Web browser secureness with respect to CVSS

  • Joh, HyunChul
    • Proceedings of the Korea Information Processing Society Conference
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    • 2014.11a
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    • pp.464-465
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    • 2014
  • Analysis of characteristics in software vulnerabilities can be used to assess security risks and to determine the resources needed to develop patches quickly to handle vulnerability discovered. Being a new research area, the quantitative aspects of software vulnerabilities and risk assessments have not been fully investigated. However, further detailed studies are required related to the security risk assessment, using rigorous analysis of actual data which can assist decision makers to maximize the returns on their security related efforts. In this paper, quantitative software vulnerability analysis has been presented for major Web browsers (Internet Explorer (IE), Firefox (FX), Chrome (CR) and Safari (SF)) with respect to the Common Vulnerability Scoring System (CVSS). The results show that, almost all the time, vulnerabilities are compromised from remote networks with no authentication required systems, and exploitation aftermath is getting worse.

Prediction of nonresponsiveness to mediumdose intravenous immunoglobulin (1 g/kg) treatment: an effective and safe schedule of acute treatment for Kawasaki disease

  • Moon, Kyung Pil;Kim, Beom Joon;Lee, Kyu Jin;Oh, Jin Hee;Han, Ji Whan;Lee, Kyung Yil;Lee, Soon Ju
    • Clinical and Experimental Pediatrics
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    • v.59 no.4
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    • pp.178-182
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    • 2016
  • Purpose: Medium-dose (1 g/kg) intravenous immunoglobulin (IVIG) is effective in the majority of patients with Kawasaki disease (KD) but some patients who do not respond to medium-dose IVIG are at high risk for the development of coronary artery lesions (CALs). The purpose of this study was to identify the clinical predictors associated with unresponsiveness to medium-dose IVIG and the development of CALs. Methods: A retrospective study was performed in 91 children with KD who were treated with mediumdose IVIG at our institution from January 2004 to December 2013. We classified the patients into responders (group 1; n=68) and nonresponders (group 2; n=23). We compared demographic, laboratory, and echocardiographic data between the 2 groups. Results: Multivariate logistic regression analysis identified 6 variables as predictors for resistance to medium-dose IVIG. We generated a predictive scoring system assigning 1 point each for percentage of neutrophils ${\geq}65%$, C-reactive protein ${\geq}100mg/L$, aspartate aminotransferase ${\geq}100IU/L$, and alanine aminotransferase ${\geq}100IU/L$, as well as 2 points for less than 5 days of illness, and serum sodium level ${\leq}136mmol/L$. Using a cutoff point of ${\geq}4$ with this scoring system, we could predict nonresponsiveness to medium-dose IVIG with 74% sensitivity and 71% specificity. Conclusion: If a patient has a low-risk score in this system, medium-dose IVIG can be recommended as the initial treatment. Through this process, we can minimize the adverse effects of high-dose IVIG and incidence of CALs.