• Journal of the Institute of Electronics Engineers of Korea TC
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• v.47 no.7
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• pp.128-134
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• 2010

In this paper, a high-power 20-way stripline power divider with low insertion loss and low side lobe level is successfully designed, fabricated and measured as a feed network for an S-band linear array antenna having Dolph-Chebyshev current distribution which has a narrow beam width and very low side lobe level (SLL). The 20-way stripline power divider consists of an 8-way power divider, three 4-way power dividers and three ring hybrids. It utilizes a T-junction structure as a basic element for power dividing. Notches and modified input/output N-to-stripline transitions are used for improving insertion loss and return loss. The fabricated power divider shows insertion loss less than 0.3 ㏈ and rms phase mismatch less than 8o in the full bandwidth. A final 40-way power divider is synthesized by combining symmetrically two 20-way power dividers and is expected to have SLL over 40 dB, based on the measured results of the 20-way power divider.

• The Journal of the Korea institute of electronic communication sciences
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• v.12 no.1
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• pp.25-30
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• 2017

In this paper, dual band patch antenna was designed using a CSRR structure with negative values permeability which inserted into the ground plane. We propose an antenna that can be used in dual band f1(1.53GHz) and f2(1.63GHz) for satellite communications by using the CSRR placed on the backside of feeding line, which is a negative shape of SRR. The proposed antenna can be arrayed using microstrip line and can be made smaller than conventional patch antenna. The fabricated antenna has the input reflection coefficient of -12.5dB and -14.5dB at f1 and f2, and the gain of 2dB and -0.8dB, respectively. and it was confirmed that the performance was sufficient in the dual-band.

• Journal of Mechanical Science and Technology
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• v.17 no.12
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• pp.1835-1843
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• 2003

This paper introduces the development of the caliper system for a geometry PIG (Pipeline Inspection Gauge). The objective of the caliper system is to detect and measure dents, wrinkles, and ovalities affect the pipe structural integrity. The developed caliper system consists of a finger arm, an anisotropic permanent magnet, a back yoke, pins, pinholes and a linear hall effect sensor. The angle displacement of the finger arm is measured by the change of the magnetic field in sensing module. Therefore the sensitivity of the caliper system mainly depends on the magnitude of the magnetic field inside the sensing module. In this research, the ring shaped anisotropic permanent magnet and linear hall effect sensors were used to produce and measure the magnetic field. The structure of the permanent magnet, the back yoke and pinhole positions were optimized that the magnitude of the magnetic field range between a high of 0.1020 Tesla and a low of zero by using three dimensional nonlinear finite element methods. A simulator was fabricated to prove the effectiveness of the developed caliper system and the computational scheme using the finite element method. The experimental results show that the developed caliper system is quite efficient for the geometry PIG with good performance.

• Proceedings of the Korea Society of Poultry Science Conference
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• 2005.11a
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• pp.31-43
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• 2005

Isoflavones are naturally occurring plant chemicals belonging to the 'phytoestrogen' class. The isoflavones are strikingly similar in chemical structure to natural estrogens. The phenolic ring is a key structural element of most compounds that bind to estrogen receptors. Dietary components that recently have received attention for their action as phytoestrogens are soy isoflavones. Soy products are the most significant dietary sources of isoflavones. Recently It is concerned clinical nutrition of isoflavone that is driven by reason of alternative sources of exogenous estrogen are constantly being needed. Estrogen therapy after the menopause offers protection from cardiovascular disease, reduces the extent of osteoporosis and relieves menopausal symptoms. Exogenous estrogen treatment is a fear of possible increased risk of developing breast cancer and because of side effects. Daily intake of soybean or soy food can affirmative effect to disease occurrence, that is based on mechanical investigation, experimental results of animals and human. Research into isoflavone is going on various field to relieve hormone - dependent disease such as cancer, menopausal symptom, cardiovascular disease and osteoporosis. Isoflavone is plenty in soybean meal, soy by-product, but only limited information is available on isoflavone efficacy into animal husbandry. Thus we conducted three experiments to investigate the effects of dietary isoflavone on productivities, antioxidative responses and bone metabolism in poultry. Dietary supplementation of isoflavone resulted in preventing the lipid oxidation of plasma and egg yolk. Dietary isoflavone improved bone development in egg-type growing chicks and broilers in terms of tibial strength. It was suggested that the proper use of feed additives such as isoflavone might provide means of improving antioxidative effect, skeletal strength, egg and eggshell quality.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.34 no.7
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• pp.805-811
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• 2010

When we design a product, we spend a considerable amount of time in designing fasteners and their mating parts. Fasteners have special features because of which they are widely used and well standardized. Although we use some equations to design the fasteners, we should select these fasteners from the standardized table. In order to design them quickly using the CAD system, we proceeded as follows. First, we prepared some standardized shapes of fasteners to design them automatically. Next, we built a database of some fasteners such as a tension bolt, lock wire, thread, pin, and snap ring. Then, we used the design equations to quickly and precisely calculate the various parameters. Finally, we used a configuration design method to generate the shapes automatically using the results of the calculation and the values retrieved from the database. We applied this approach to the design of a propulsion structure, and demonstrated that this approach worked well and saved considerable time.

• Applied Chemistry for Engineering
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• v.18 no.2
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• pp.116-120
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• 2007

The synthesis of 1-[2-(3-{7-oxabicyclo[4.1.0]heptyl} 1,1,3,3-tetramethyl-disiloxane (Mono), which is a key intermediate for the synthesis of monomers applied for photopolymer systems based on the cationic ring opening polymerization, was studied. Mono was successfully synthesized by the hydrosilylation reaction of 4-vinyl-1-cyclohexene 1,2-epoxide (VCHO) with an excess amount of 1,1,3,3-tetramethyldisiloxane (TMDS) in the presence of a Speier catalyst. The structure and the purity of Mono were characterized by FT-IR, $^1H-NMR$, and $^{29}Si-NMR$. The optimum conditions for the hydrosilyation reaction were found to be 1:4 molar ratio of VCHO to TMDS and 5 ppm of the catalyst at the temperature of $55^{\circ}C$.

• Bulletin of the Korean Chemical Society
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• v.32 no.12
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• pp.4185-4190
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• 2011

The nucleophilic substitution reactions of ethylene phosphorochloridate (1c) with substituted anilines ($XC_6H_4NH_2$) and deuterated anilines ($XC_6H_4ND_2$) are investigated kinetically in acetonitrile at $5.0^{\circ}C$. The anilinolysis rate of 1c involving a cyclic five-membered ring is four thousand times faster than its acyclic counterpart (1a: diethyl chlorophosphate) because of great positive value of the entropy of activation of 1c (${\Delta}S^{\neq}=+30\;cal\;mol^{-1}K^{-1}$ compared to negative value of 1a (${\Delta}S^{\neq}=-45\;cal\;mol^{-1}K^{-1}$) over considerably unfavorable enthalpy of activation of 1c (${\Delta}H^{\neq}=27.7\;kcal\;mol^{-1}$) compared to 1a (${\Delta}H^{\neq}=8.3\;kcal\;mol^{-1}$). Great enthalpy and positive entropy of activation are ascribed to sterically congested transition state (TS) and solvent structure breaking in the TS. The free energy correlations exhibit biphasic concave upwards for substituent X variations in the X-anilines with a break point at X = 3-Me. The deuterium kinetic isotope effects are secondary inverse ($k_H/k_D$ < 1) with the strongly basic anilines and primary normal ($k_H/k_D$ > 1) with the weakly basic anilines and rationalized by the TS variation from a dominant backside attack to a dominant frontside attack, respectively. A concerted $S_N2$ mechanism is proposed and the primary normal deuterium kinetic isotope effects are substantiated by a hydrogen bonded, four-center-type TS.

• Archives of Pharmacal Research
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• v.24 no.1
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• pp.44-50
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• 2001

To search for cytotoxic components from Allium victoriallis , MTT assays on each extract and an isolated component, gitogenin 3-O-lycotetroside, were performed against cancer cell lines. Cytotoxicities of most extract were shown to be comparatively weak, though $IC_50$ values of $CHCl_3$fraction was found to be <31.3-368.4 $\mu\textrm{g}/ml$. From the incubated methanol extract at $36^{\circ}C, eleven kinds of organosulfuric flavours were predictable by CG-MS performance. The most abundant peak was revealed to be 2-vinyl-4H-1,3-dithiin(1) by its mass spectrum. Further, this extract showed significant cytotoxicities toward cancer cell lies. Silica gel column chromatography of the n-butanol fraction led to the isolation of gitogenin 3-O-lycotetroside (3) along with astragalin (4) and kaempferol 3, 4'-di-O-$\beta$-D-glycoside (5). This steroidal saponin exhibited significant cytotoxic activities ($IC_50$, 6.51-36.5 $\mu\textrm{g}/ml$) over several cancer cell lines. When compound 3 was incubated for 24 h with human intestinal bacteria, a major metabolite was produced and then isolated by silica gel column chromatography. By examining parent and prominent ion peak in FAB-MS spectrum of the metabolite, the structure was speculated not to be any of prosapogenins of 3, suggesting that spiroketal ring were labile to the bacterial reaction. These suggest that disulfides produced secondarily are the antitumor principles.

• Korean Journal of Pharmacognosy
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• v.17 no.2
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• pp.153-160
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• 1986

We have isolated two new metabolites of territrem, designated as territrem $A'\;(TRA';\;C_{28}H_{30}O_{10})$ and $B'\;(TRB';\; C_{29}H_{34}O_{10})$ from chloroform extract of rice culture of Aspergillus terreus 23-1, using the same isolation procedure as that for territrem A, B and C(TRA, TRB, TRC). The present isolation procedure gave about 5 mg of TRA' and 10 mg of TRB' from 4 kg of rice culture per batch. Analysis of the high resolution mass spectrum showed that the molecular composition of TRA' and TRB' are $C_{28}H_{30}O_{10}$ and $C_{29}H_{34}O_{10}$ respectively, Some results of physicochemical properties were presented in this paper. Single crystal X-ray diffractometry of TRB' showed that the three dimensional structure of TRB' has not changed significantly from that of $TRB\;(C_{29}H_{34}O_9)$, except for the insertion of one oxygen atom into TRB to make additional pyran in the E-ring. It is also suggested that the aromatic moiety of TRA' is similar to that of $TRA\;(C_{28}H_{30}O_9)$ and the rest non-aromatic portions resemble to those of TRB'. The tremorgenic activity, lethality and inhibitory effect on acetylcholine esterase of TRA' and TRB' are greatly reduced comparing to that of TRA and TRB.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.517-535
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• 2014

Poly (lactic-co-glycolic acid) (PLGA) is one of the most effective biodegradable polymeric nanoparticles (NPs). It has been approved by the US FDA to use in drug delivery systems due to controlled and sustained-release properties, low toxicity, and biocompatibility with tissue and cells. In the present review, the structure and properties of PLGA copolymers synthesized by ring-opening polymerization of DL-lactide and glicolide were characterized using 1H nuclear magnetic resonance spectroscopy, gel permeation chromatography, Fourier transform infrared spectroscopy and differential scanning calorimetry. Methods of preparation and characterization, various surface modifications, encapsulation of diverse anticancer drugs, active or passive tumor targeting and different release mechanisms of PLGA nanoparticles are discussed. Increasing experience in the application of PLGA nanoparticles has provided a promising future for use of these nanoparticles in cancer treatment, with high efficacy and few side effects.