• 제목/요약/키워드: right factor

검색결과 804건 처리시간 0.031초

The effect of sildenafil on right ventricular remodeling in a rat model of monocrotaline-induced right ventricular failure

  • Bae, Hyun Kyung;Lee, Hyeryon;Kim, Kwan Chang;Hong, Young Mi
    • Clinical and Experimental Pediatrics
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    • 제59권6호
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    • pp.262-270
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    • 2016
  • Purpose: Pulmonary arterial hypertension (PAH) leads to right ventricular failure (RVF) as well as an increase in pulmonary vascular resistance. Our purpose was to study the effect of sildenafil on right ventricular remodeling in a rat model of monocrotaline (MCT)-induced RVF. Methods: The rats were distributed randomly into 3 groups. The control (C) group, the monocrotaline (M) group (MCT 60 mg/kg) and the sildenafil (S) group (MCT 60 mg/kg+ sildenafil 30 mg/kg/day for 28 days). Masson Trichrome staining was used for heart tissues. Western blot analysis and immunohistochemical staining were performed. Results: The mean right ventricular pressure (RVP) was significantly lower in the S group at weeks 1, 2, and 4. The number of intra-acinar arteries and the medial wall thickness of the pulmonary arterioles significantly lessened in the S group at week 4. The collagen content also decreased in heart tissues in the S group at week 4. Protein expression levels of B-cell lymphoma-2 (Bcl-2)-associated X, caspase-3, Bcl-2, interleukin (IL)-6, matrix metalloproteinase (MMP)-2, endothelial nitric oxide synthase (eNOS), endothelin (ET)-1 and ET receptor A (ERA) in lung tissues greatly decreased in the S group at week 4 according to immunohistochemical staining. According to Western blotting, protein expression levels of troponin I, brain natriuretic peptide, caspase-3, Bcl-2, tumor necrosis factor-${\alpha}$, IL-6, MMP-2, eNOS, ET-1, and ERA in heart tissues greatly diminished in the S group at week 4. Conclusion: Sildenafil alleviated right ventricular hypertrophy and mean RVP. These data suggest that sildenafil improves right ventricular function.

서킷 웨이트트레이닝이 노인들의 등속성 근력과 신체구성에 미치는 영향 (Effects of Circuit Weight Training on Isokinetic Muscle Strength and Body Composition in elderly)

  • 장정훈;정동혁
    • The Journal of Korean Physical Therapy
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    • 제15권4호
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    • pp.398-411
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    • 2003
  • The purpose of this study was to investigate the effects of circuit weight training(CWT) on isokinetic muscle strength and body composition in elderly. The subjects who engaged in this experiment exercised at $40\%$ of 1-RM, 12 repetitions, followed by 15 sec as the subject moved to the each break training program which was consist of the circuit of 10 stations performed on 3 set a day, circuits 3 days a week during 10 weeks. The assessment of isokinetic factor was in concentric flexors and extensors of right and left knee joint. Tests were performed on the Cybex 770 Isokinetic Dynamometer and body composition were estimated the three parts of chest, abdomen and anterior thigh by using skinfold caliper, calculated the average and followed by Seri and Brozek way. Statistical analysis were performed using analysis of variance paired t-test, accepting level for all significant was above ${\alpha}=.05$ and ${\alpha}=.01$. Following is as a result of 10 weeks circuit weight training. 1. At the $60_{\circ}$ /sec, the right and left knee isokinetic concentric flexors and extensors peak torque increased significantly(p<.01). 2. At the $180_{\circ}$ /sec, the right and left knee isokinetic concentric flexors and extensors peak torque increased significantly(p<.01). 3. At the $60_{\circ}$ /sec, the right and left knee isokenetic concentric flexors and extensors average power increased significantly(p<.05, p<.01) and at the $180_{\circ}$ /sec, the right extensors didn't show any statistical significant. 4. At the $60_{\circ}$ /sec, the right and left knee Isokinetic concentric flexors and extensors total work increased significantly(p<.05, p<.01) but at the $180_{\circ}$ /sec right concentric flexors didn't show any statistical significant. 5. The body composition changed significantly(p<.01). These results suggest that 10 weeks circuit weight training increases the peak torque, average power, total work significantly and decreases the $\%$body fat significantly.

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인터넷에 올라와 있는 개인정보의 자기결정권과 통제권에 관한 연구 (Study on Decision-making and Control of Personal Data Posted on the Internet)

  • 윤경배
    • 한국인터넷방송통신학회논문지
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    • 제14권4호
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    • pp.227-232
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    • 2014
  • 인터넷 기술이 발전되고, 보편화 되면서 상업과 자본의 대형화가 이루어져 대형 포털 사이트들이 등장하고 성장하게 되면서 인터넷상에서 시간이 흘러도 삭제되지 않는 개인정보 때문에 심각한 사생활 침해문제 등 새로운 위험요소가 제기되고 있다. 특히 마녀사냥 같은 개인의 신상 털기는 피해 당사자가 정상적인 생활이 불가능할 정도의 중대한 문제로 부각되고 있다. 따라서 본 논문에서는 국내외 사례분석을 통하여 개인이 온라인 사이트에 올라와 있는 자신과 관련된 정보 삭제를 요구할 수 있는 권리의 필요성과 국내 도입방안 및 적용에 관한 개선방안을 제안한다.

INJECTIVE PROPERTY RELATIVE TO NONSINGULAR EXACT SEQUENCES

  • Arabi-Kakavand, Marzieh;Asgari, Shadi;Tolooei, Yaser
    • 대한수학회보
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    • 제54권2호
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    • pp.559-571
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    • 2017
  • We investigate modules M having the injective property relative to nonsingular modules. Such modules are called "$\mathcal{N}$-injective modules". It is shown that M is an $\mathcal{N}$-injective R-module if and only if the annihilator of $Z_2(R_R)$ in M is equal to the annihilator of $Z_2(R_R)$ in E(M). Every $\mathcal{N}$-injective R-module is injective precisely when R is a right nonsingular ring. We prove that the endomorphism ring of an $\mathcal{N}$-injective module has a von Neumann regular factor ring. Every (finitely generated, cyclic, free) R-module is $\mathcal{N}$-injective, if and only if $R^{(\mathbb{N})}$ is $\mathcal{N}$-injective, if and only if R is right t-semisimple. The $\mathcal{N}$-injective property is characterized for right extending rings, semilocal rings and rings of finite reduced rank. Using the $\mathcal{N}$-injective property, we determine the rings whose all nonsingular cyclic modules are injective.

만성 염증성 폐질환의 전폐적축술 후 합병증에 영향을 미치는 요인 (Factors Affecting Postoperative Complication in Pneumonectomy for Chronic Complicated Inflammatory Lung Disease)

  • 최필조;우종수
    • Journal of Chest Surgery
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    • 제33권1호
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    • pp.73-78
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    • 2000
  • Background: this study was designed to estimate whether specific risk factors could increase the postoperative complication rate of pneumonectomy for chronic complicated inf-lammatory lung disease. Material and Method: Eighty-five patients underwent pneumon-ectomy for chronic complicated inflammatory lung disease(tuberculosis, 67 ; bronchiecasis 11; aspergio- losis, 4; others, 3) between January 1991 and August 1998. We performed a univariated statistical analysis to identify preoperative and intraoperative risk factors associated with postoperative complications, Result: There was no operative mortality. There were a total of 18 postoperative complications(22.2%) Bronchopleural fistula(BPF) and empyema occurred in 5(5.9%) and 2(2.4%) respectively. General complication rate was significantly higher in patients with right-sided pneumonectomy(p=.029) extrapleural pneu-monectomy(p=.009) and intraoperative pleural spillage due to cavity or lesion perforation (p=.004). The prevalence of BPF and empyema was higher in patients with right sided pneumonectomy(p=.007) extrapleural pneumonectomy(p=.015) and intraoperative pl- eural spillage due to cavity or lesion perforation(p=.003) which is as the same results as gen-eral complication rate. Conclusion: The postoperative complication rate of pneumone-ctomy for chronic complicated lung disease is accptably low. But it is increase in patients with right sided pneumonectomy extrapleural pneumonectomy and intraoperative pleural spillage due to cavity or lesion perforation. therefore more careful and meticulous intra-operatve management are needed in right sided extrapleural pneumonectomy without intra- pleural spillage.

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Vergence Control of Binocular Stereoscopic Camera Using Disparity Information

  • Kwon, Ki-Chul;Lim, Young-Tae;Kim, Nam;Song, Young-Jun;Choi, Young-Soo
    • Journal of the Optical Society of Korea
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    • 제13권3호
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    • pp.379-385
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    • 2009
  • The vergence control of binocular stereoscopic camera is the most essential factor for acquiring high quality stereoscopic images. In this paper, we proposed a binocular stereoscopic camera vergence control method using disparity information by the simple image processing and estimate the quantity of vergence control using the Lagrange interpolation equation. The method of extracting disparity information through image processing is as follows: first the key-object in left & right images was extracted through labeling of the central area of the image, and then a simple method was used for calculating the disparity value of the same key-object in the labeled left and right images. The vergence control method uses disparity information and keeps the convergence distance of left & right cameras and the distance of the key-object the same. According to the proposed method, variance in the distance of the key-object and application of calculated disparity information of obtained left & right images to the quadratic Lagrange interpolation equation could estimate the quantity of vergence control, which confirmed that the method of stereoscopic camera vergence control can be simplified through experiments on various key-objects and other convergence distance.

비틀림 동작에서의 허리근육의 피로도 패턴 (Fatigue Patterns on Trunk Muscles at Various Asymmetric Twisting Conditions)

  • 조영진;김정룡
    • 대한인간공학회지
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    • 제20권2호
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    • pp.71-82
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    • 2001
  • Twisting posture in lifting tasks has been identified as a risk factor of low back pain. However, it has been usually estimated in terms of compressive stress or muscular activity. Thus, this study was conducted to predict the influence on muscular fatigue during lifting simulation. Fifteen young and healthy subjects were recruited and performed isometric trunk exertions during upright standing, two-level flexions and five-level asymmetric twisting conditions. EMG signals from five primary trunk muscles in right part of body were collected during 20sec for 45 different lifting conditions. RMS(root mean square) and MPF(mean power frequency) parameters were used to analyze the EMG signals. Twisting postures were significant in right erector spinae(ERSR), right latissimus dorsi(LATR), right internal oblique(INOR) for muscular activities. Especially, when trunk was $30^{\circ}$ CCW twisting posture. ERSR and INOR activities increased respectively by 11% and 3%. Regarding the trunk muscle fatigue, we found that MPF shifts in twisting posture increased 2.3 and 2.6 times for ERSR and INOR muscles respectively. Therefore, It is probable for workers to suffer from low back disorders when they were exposed to a extreme twisting posture during prolonged lifting. This study suggests NIOSH(National Institute for Occupational Safety and Health) lifting equation needs the time-duration multiplier in addition to asymmetric multiplier.

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시각정보의 인식도에 의한 자동차 Side Mirror의 최적 위치결정에 관한 연구 (A Study on the Optimal Position of Vehicle Side Mirrors according to the Perception of Visual Information)

  • 김도회;이근희
    • 산업경영시스템학회지
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    • 제14권24호
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    • pp.123-132
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    • 1991
  • This study deals with the experiment of perceiving visual information according to the positions of vehicle side mirrors. In the design of vehicle, the consideration of safety is very important. Therefore we consider the positions of side mirrors to use visual information effectively which is important factor to driver. This paper presents the position of side mirror to elevate the degree of visual perception for the circumstances of danger by experiments. To exhibit the circumstances of danger. 4 LED(Light Emitted Diode) art located at each side(right. left front. hack) of vehicle. A subject pushes the LED switch to see that if he perceives the circumstance of danger. To record the circumstance of randomly generated danger, computer interface card is used to control 4 LED and swithch on IBM PC/AT Experiments are divided into 2 parts. The 1st experiment present the independence of right & left side mirror. The 2nd experiment present optimal position of right & left side mirror. The vehicle used in experiment is model EL of H Co.. Statistical process of experimental data using SPSS(Statistical Package for Social Sciences)/PC package concludes that 1) the optimal position of right side mirror is 54cm forward of exist position. 2) for the left side mirror, the position of 120cm forward of exist position shows the worst degree of perception. and the optimal position does not exist in statistical meaning.

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장애인의 문화적 권리 보장에 대한 소고 (A View on the Guarantee of Cultural Right of the Disabled)

  • 이문화
    • 한국콘텐츠학회논문지
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    • 제14권9호
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    • pp.267-274
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    • 2014
  • 문화는 사회구성원의 삶의 질을 논함에 있어 필수적인 요소이며, 문화권은 국민의 기본적인 권리로서 인정받고 있다. 문화권이란 시민들이 문화향수를 위해 필요한 각종 문화적 생산수단을 공적으로 확보하고, 문화적 활동에 쉽게 접근할 수 있는 환경을 요구하는 것을 말한다. 그러나 우리사회에서 장애인의 문화권은 사회적 편견과 장벽으로 차별과 소외의 상태에 머물러 있으며 그것은 아직도 권리로서의 인식이 부족한 데서 기인한 것이라고 볼 수 있다. 본 연구의 목적은 장애인의 문화적 권리는 기본적인 인간의 권리라는 인식의 제고와 함께 그에 기반한 보편적 권리임을 분명히 하고, 장애인의 문화적 평등권 실현을 위한 적극적 조치(Affirmative Action)의 시행을 주장하는 데에 있다. 본 연구를 통해 도출된 장애인 문화권 보장과 실현을 위한 정책적 방안은 다음과 같다. 첫째, 기초생활보장수급자와 차상위 계층으로 한정된 문화바우처 사업의 대상을 모든 장애인으로 확대해야 한다. 둘째, 문화체육관광부 산하에 장애인 문화지원을 전담하는 독립된 장애인문화국의 설치가 필요하다. 셋째, 주기적으로 장애인의 문화 활동과 문화욕구에 관한 전국단위의 실태조사가 요구된다.

주시안과 눈꺼풀 올림근 기능의 상관관계 분석 (Correlation Analysis of Ocular Dominance and Levator Palpebrae Superioris Muscle Function)

  • 하기영;서현우;김부영;김태연;박성규
    • Archives of Plastic Surgery
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    • 제37권3호
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    • pp.265-270
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    • 2010
  • Purpose: Most of the bilateral structures in our body are not perfectly balanced, such that one side is preferred than the other or it has physiological superiority. Eyes also have an imbalance; the eye with sensory and motional superiority compared to the other is called dominant eye. Authors of this study focused on analyzing the correlation between the dominant eye and levator palpebrae superioris muscle. Methods: The subject of this study was 42 patients with no ptosis and with no past history of blepharoplasty. Hand dominance was identified through questionnaire and dominant eye was identified by hole-in-the-card dominance test (Dolman's test) in all patients. The function of levator palpebrae superioris muscle was measured by MLD (marginal limbal distance). During the measuring procedure, frontalis muscle was not inhibited to avoid the eyelid skin hooding. Results: Out of 42 patients, 27 patients (64.3%) were right ocular dominant, 15 patients (35.7%) were left ocular dominant, 36 patients (85.7%) were right hand dominant and 4 patients (9.5%) were left hand dominant. Out of 27 right ocular dominant patients, right MLD was larger than the left in 26 patients (96.3%). It was larger in average of 0.47 mm (p<0.001) in 27 right ocular dominant patients. Also, left MLD was larger than the right in 11 patients (73.3%) out of 15 left ocular dominant patients. It was larger in average of 0.57 mm (p=0.003) in 27 left ocular dominant patients. MLD on the side of the dominant eye was larger in average of 0.50 mm (p<0.001) than the MLD of non-dominant eye side. Right MLD was larger than the left in average of 0.28mm (p=0.010) in right hand dominant patients, and left MLD was larger than the right in average of 1.15 mm (p=0.025) in left hand dominant patients. Conclusion: The function of levator palpebrae muscle differs in right and left, and the difference correlates with the dominant eye. Also, the function of levator palpebrae muscle is stronger in the dominant eye. We were able to present statistical evidence regarding the difference of the function in right and left levator palpebrae muscle. This may be a factor worth consideration in terms of balancing the eyes during the blepharoplasty.