• Korean Journal of Clinical Pharmacy
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• v.21 no.4
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• pp.339-346
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• 2011

Over the past few decades, drug regulatory agencies in advanced countries have been emphasizing pharmacometrics as a tool for an effective and efficient drug evaluation. Despite this international movement, the value of pharmacometrics is still poorly recognized by the Korean drug evaluation system. This study aimed to analyze the current state of utilization of pharmacometrics by foreign drug regulatory agencies and develop a road map to guide the implementation pharmacometrics into the Korean drug evaluation system. MEDLINE and foreign drug regulatory agency database were extensively searched to obtain scientific research articles, guidance, regulations and pharmacometric review reports on foreign pharmacometric drug evaluation system. A systematic roadmap comprised of 3 stages to implement pharmacometrics in Korean drug evaluation system was formulated after analyzing the collected data in tune with the current evaluation system. Pharmacometrics is an urgently required tool to achieve an efficient drug evaluation and review in Korea. The road map developed by this study is expected to aid in setting up a policy to implement and utilize pharmacometrics in Korea.

• Quality Improvement in Health Care
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• v.25 no.1
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• pp.11-28
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• 2019

Purpose: The purpose of this paper is to derive implication on the adoption of PROMs (Patient-Reported Outcome Measures) to improve quality of care in South Korea. With this purpose, the paper examines the status of PROMs in South Korea and other countries including OECD's PaRIS (Patient Reported Indicators Survey) initiative, and reviews policy cases that have adopted PROMs to improve performance of healthcare system. Methods: We conducted literature review on OECD reports on PaRIS, peer-reviewed journals, and information from the websites of relevant institutions such as ICHOM, NQF and OECD. Results: To identify healthcare services of best values and support patient-centered health system, OECD has initiated PaRIS which develops, collects and analyzes patient-reported indicators for cross-countries comparison. PaRIS is implemented on two work streams: 1) collect, validate and standardize PROMs in the areas where patient-reported indicators already exist such as breast cancers, hip and knee replacement, and mental conditions, 2) develop a new international survey on multiple chronic conditions. Countries like England, U.S., Sweden and Netherlands use PROMs for measuring performance of hospitals and performance evaluation at the national level, and provide the financial incentives for reporting PROMs. Conclusions: The use of PROMs can support the current policy agenda that is the patient-centered healthcare system which has been emphasized to reinforce the primary and the community-based care. For the use of PROMs, it is recommended to actively participate in PaRIS initiative by OECD, select appropriate instruments for PROMs, and continue on standardization of them. This will assure patients' involvement in improving health system performance, systemize information generated in the process of adopting PROMs, and develop a system to evaluate performance.

• Neonatal Medicine
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• v.18 no.1
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• pp.1-5
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• 2011

Coagulation involves the regulated sequence of proteolytic activation of a series of proteins to achieve appropriate and timely hemostasis in an injured vessel. In the non-pathological state, the inciting event involves exposure of circulating factor VIIa to extravascularly expressed tissue factor, which brings into motion the series of steps which results in cell based model of coagulation. In the new concepts of coagulation system, initiation, amplification and propagation steps are involved to converse of fibrinogen to fibrin. The precisely synchronized cascade of events is counter-balanced by a system of anticoagulant mechanisms. Developmental hemostasis refers to the age-related changes in the coagulation system that are most marked during neonate and childhood. An understanding of these changes in crucial to the accurate diagnosis of hemostatic abnormalities in neonate and children. This review aims to elucidate the main events within the coagulation cascade as it is currently understood to operate in vivo, and also a short review of the anticoagulants as they relate to this model. Also this paper describes the common pitfalls observed in the clinical data related to the coagulation system in neonate to children.

• Hwankyungkyoyuk
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• v.14 no.1
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• pp.43-55
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• 2001

The purpose of this study was to review the current status and problems of the national qualification system in the Environmental field focusing on deficiencies of the regulatory system and qualities of environmental professional including the Environmental control Professional Engineer, Environmental Engineer, Environmental Industrial Engineer and Environmental field. An overview of the environmental field, its current status, domestic qualification items and training conditions in environment-related areas, laws of environmental field, and data of the job analysis were reviewed. The concrete and extensive development plans for the qualification system of the Environmental field are as follows: First of all, a job analysis should be made of on the introduction of new systems or policy modification to reflect technical changes and national policies about the environmental field in the qualification exam. Second, it is essential to prepare policies that are suitable for the qualification system in the Environmental field and that improve its effectiveness. Third, the appropriate policy measures should be taken in order to elevate the social standing of Environmental field qualification holders.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.12 no.1
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• pp.80-92
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• 2008

Background: The consequences of disordered breathing patterns are not only distressing to the patient but also expensive to our health care systems if they are not diagnosed and treated. So we performed this study to investigate clinical significants trough gigong, yoga and hyperventilation in oriental medicine and westen medicine Objective: To review the relationship of electrogastrography with autonomic nervous system and to study its clinical application. Method: We investigate the research results through internet search engine, Pubmed. Conclusion: Electrogastrography is a reliable, non-invasive method for recording gastric myoelectrical activity and is used for objectification of diagnosis related to gastric peristalsis. Gastric myoelectrical activity seem to involve autonomic nervous system, especially parasympathetic nervous system. The study should be continuing about relationship between electrogastrography and autonomic nervous system.

• Journal of Korean Society on Water Environment
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• v.34 no.3
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• pp.339-345
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• 2018

The integrated environmental permit system is currently in operation online. It carries out various functions of postmanagement such as the submission of annual reports containing operations management data onto integrated management workplaces, the operation and management of emission facilities and prevention facilities, and the disclosure of information on the integrated permission. On the other hand, the integrated environmental permit system needs to perform various roles in order to stably manage and smoothly perform the permitting work. It is necessary to utilize this system to establish policies by using diverse operations management data onto integrated management workplaces collected in the integrated environmental permit system. This system can also play a role in improving the post-management system and user convenience after the permission review and approval processes. The integrated environmental permit system can be effectively used to set up the BAT-AEL because it collects all of the cross-media data and identifies the overall status of the workplace. In order to establish a post management system after the approval, it is necessary to provide performance management and performance evaluation functions as conditions of the permit after approval. In addition, a variety of support functions should be provided to enable the permission authority and the environmental expert examination agency to facilitate the review of permits. It will be necessary to provide an evaluation system and a proactive diagnostic function to determine whether permission conditions and permit emission standards will change in the future. Also, it is important to adopt an information exchange platform that can be used to collect the status data onto the workplaces; the platform can also be used as an information exchange site for technical working groups (TWG), and for collecting field experts' opinions.

• Proceedings of the Society of Korea Industrial and System Engineering Conference
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• 2002.05a
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• pp.349-357
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• 2002

This research is basically deals with an inventory distribution system with several regional sales branches. Under the continuous review policy, each sales branch places an order to its supplier whenever on hand plus on order inventory falls on the order point, and the order quantity is received after elapsing a certain lead time. This research first shows the method how to apply the product with low lever of demand into the continuous review policy. For the application, we use an order level as the maximum level of inventory during an order cycle. Also we analyze the lost sales case as a customer behavior. Further we use variable demands and variable lead times for more realistic situation. Based on the above circumstances, the research mainly discusses those methods to decide the optimal order level, order point, and order quantity for each sales branch which guarantees the system wide goal level of service, while keeping the minimum level of the system wide total inventory.

• Journal of the Korea Society of Computer and Information
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• v.21 no.12
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• pp.173-178
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• 2016

In this paper many discussions are raised regarding the outside director system in order to establish the position of the outside director within institutional organizations and to review ways to activate the outside director system in for-Profit Hospital. it seems to be more desirable in Korea for each company to establish an efficient system by itself in accordance with suggested guidelines suitable for each for-Profit Hospital management circumstances rather than to apply a unilateral outside director system to for-Profit Hospital through legalization. In this regard, while keeping the current outside director system for the time being, it is necessary to review and improve the management status of companies and the usefulness of the system, and various recommendations from lawyer associations, Hospital business associations, and academia should be allowed rather than just for-Profit Hospital recommendation by the government.

• Journal of the Korea Society of Computer and Information
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• v.17 no.10
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• pp.203-216
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• 2012

For the successful operation of the current organization, the importance of the information system is further increasing, and audit for the information system construction is also spreading according to the mandatory of information system audit. However our country's information system audit still does not deal with various risks and the improvement plan of it is desperately needed since bad practices are often happened while performing audit for the various information system projects. Therefore, this paper proposed improved review items for the quality improvement of information system construction by analysing data of information system audit projects and risk occurrence projects that are performed by the domestic large SI company during four years. In addition, this paper verified the effectiveness of the improved review items proposed in this paper by applying them to actual information system project examples.

• Journal of Society of Preventive Korean Medicine
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• v.20 no.2
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• pp.27-38
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• 2016

Backgrounds : Taiwan has similar national health insurance (NHI) system for traditional medicine with South Korea. Recently, new quality improvement policies for traditional medicine is being attempted in Taiwan. Objectives : This study aimed to review the Taiwanese NHI system for Chinese Medicine (CM) and introduce quality improvement policies. Methods : Research articles, reports, government publications and year books which handled traditional medicine system and NHI system in Taiwan were searched and collected. The authors analyzed and summarized the contents in a qualitative manner. Results : In Taiwanese NHI system, CM procedures and medication for outpatients are reimbursed through a mix of fee-for-service and global budget payment system. CM shares 4% of total expenditure of NHI in Taiwan. Mostly, the expenses for procedures are reimbursed regardless of disease type, however, in the specialized program for quality improvement, CM doctors have to comply with standard operating procedures (SOPs). Conclusions : Taiwanese NHI system implemented SOP-based new reimbursement system for CM. Yet, the scientific evidences for SOPs are not sufficient, it can be useful references when we develope disease related reimbursement system for Korean Medicine in South Korea.