• Korean Journal of Oriental Medicine
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• v.18 no.1
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• pp.75-84
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• 2012

Objective : The purpose of this study was to investigate the anti-cancer effects of Sophorae Radix and the effects of Doxorubicin (DOX) in human breast adenocarcinoma cells (MCF-7). Method : We used human breast adenocarcinoma cell line, MCF-7 cells. We examined cell death by MTT assay and caspase 3 assay with Sophorae Radix. To examine the inhibitory effects of Sophorae Radix, cell cycle analysis was done the MCF-7 cells after three days with Sophorae Radix. The reversibility of Sophorae Radix was examined on one day to five days treatment with 100 ${\mu}g/ml$ Sophorae Radix. Result : Sophorae Radix inhibited the growth of MCF-7 cells in a dose-dependent fashion. Also we showed that Sophorae Radix induced apoptosis in MCF-7 cells by MTT assay, caspase 3 assay and sub-G1 analysis. Sophorae Radix combined with DOX markedly inhibited the growth of MCF-7 cells compared to Sophorae Radix or DOX alone. After 3 days treatment of MCF-7 cells with Sophorae Radix, the fraction of cells in sub-G1 phase was much higher than that of the control group. Conclusion : Our findings provide insight into unraveling the effects of Sophorae Radix in human breast adenocarcinoma cells and developing therapeutic agents against breast cancer.

• Journal of the Korean Ceramic Society
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• v.47 no.6
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• pp.627-632
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• 2010

In this paper the effect of the structure, particle size, morphology of nanofibers and nanoparticles for the electrochemical characteristics of $Li_4Ti_5O_{12}$ was investigated. The $H_2Ti_2O_5{\cdot}H_2O$ synthesized in hydrothermal treatment from a NaOH treatment on $TiO_2$ by ion exchange processing with HCl solutions. After the $Li_4Ti_5O_{12}$ nanofibers synthesized in hydrothermal treatment of $H_2Ti_2O_5{\cdot}H_2O$ and $LiOH{\cdot}H_2O$. The hydrogen titanate precursor prepared by ion exchange processing with 0.1~0.3M HCl solutions and the final products calcined at $350^{\circ}C{\sim}400^{\circ}C$. The $Li_4Ti_5O_{12}$ nanofibers showed well reversibility during the insertion and extraction of Li, good cycle performance, high capacity and low electrochemical reaction resistance than nanoparticles. also c-rate exhibited a discharge capacity of 172 mAh/g at 0.2C and 115mAh/g at 5C, which is the 77%, 67% of that obtained in the process charged, discharged at 0.2C.

• Journal of Environmental Science International
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• v.17 no.3
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• pp.275-285
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• 2008

The floc formation, breakage and reformation of humic acid by inorganic (alum and PAC) and organic coagulants (cationic polyelectrolytes) at several conditions (pH, ionic strength and floc breakage time) were examined and compared among the coagulants at different conditions using a continuous optical monitoring method, with controlled mixing and stirring conditions. For alum, the shapes of formation, breakage and reformation curves at different pH (5 and 7) were different, but the shapes and the sizes of initial floc and reformed floc were nearly the same in the absence and presence of electrolytes at pH 7. For PAC, similar shapes of the curves were obtained at different pH and ionic strength, but the sizes were different, except for those of reformed flocs at different pH. However, for these coagulants, reformed flocs after floc breakage, occurred irreversibly for all the conditions used in this study. For organic coagulants, the time to attain the initial plateau floc size, the extent of floc strength at high shear rate and reversibility of reformed floes were different, depending floc formation mechanism. Especially, for the cationic polyelectrolyte forming humic flocs by charge neutralization or electrostatic patch effect mechanism, reformed flocs occurred reversibly, regardless of pH and floc breakage time, but occurred irreversibly in the presence of electrolytes.

• Journal of the Korean Society of Costume
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• v.63 no.7
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• pp.65-78
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• 2013

This study aims to suggest the methodology for conservation of excavated costumes especially repair and restoration process. Early excavated costumes had not attracted attention from the field of academia and the public. So not many scholars, organization and society participated in the excavations but as its value has gotten more recognition, there has been a reversal in trend. And so many organizations have taken part in it. Excavating includes conservation processes such as washing, repair and restoring, and then it is published by reports or books after the process is complete. However the method of conservation has varied depending on the institution. In particular, repair and restore methods do not include anything specific details, and often times, only has descriptions of the before and after state, and so a more unified method needs to be suggested and shared. This study defined 'Conservation', 'Repair' and 'Restoration' and then applied it to the short history of Korean excavated-costumes. Then it suggested ways to repair and restore excavated-costumes in terms of construction, textile, and damage by the unpublished cases of excavated-costumes of Noh Su-ham(1516~1573)'s Family. It was also referred to repair and restoration process such as shaping correction, dyeing, supporting, sewing and after treatment by texts and pictures. Other contents such as a list of relics and its details, will be published through a report or a book. The whole process of conservation was in progress based on the ethical guidelines of conservation, 'Minimum intervention' and 'Reversibility'.

• Journal of the Korean Chemical Society
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• v.51 no.1
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• pp.65-72
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• 2007

The purpose of this study was to examine the 7th national science curriculum (chemistry domain) regarding the meanings of ‘mulgil' (Korean), the particulate nature of matter, and the state of matter. It was found that the term of ‘mulgil' was being used vaguely as representing material, matter, or substance without clear definition. This was problematic by reason that it could hinder students from having the concept of substance. Regarding the particulate nature of matter, molecule was introduced as a basic unit of matter at grade 7, prior to atom and ion, which were introduced at grade 9 and 10, respectively. It is necessary to reconsider the sequence of each particle concept to provide students with more consistent and comprehensive understanding of structure of matter. In the case of change of state, key concepts such as conservation of matter or reversibility were omitted in the curriculum document, and explanations based on various aspects of particles were somewhat insufficient. The concept of matter is fundamental to chemistry, and we must recognize it as a concept that needs to be taught clearly. Implications for curriculum revision were discussed.

• Proceedings of the Optical Society of Korea Conference
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• 2007.07a
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• pp.223-224
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• 2007

광기록의 역사는 1980년대초 Sony와 Philips가 공동 개발한 CD (compact disc: 640MB)의 출현으로부터 시작하여 1996년의 DVD (digital versatile disc: 4.7GB)를 거쳐 최근의 BD (Blu-ray disc: >20GB)에까지 이르고 있다. Read-only memory, recordable, rewritable 등 다양한 저장 및 재생방식이 존재하는데, 이는 레이저 조사에 의한 기록매체의 특성변화의 가역성 (reversibility)에 의존하므로 저장 및 재생방식에 따라 저장매체 또한 다르게 된다. 기록용량의 증가는 레이저의 파장이 짧아지고 동시에 사용된 렌즈의 개구수 (NA: Numerical aperture)가 증가함에 따른 빔 spot size의 감소에 기인한다. 회절한계를 극복하여 빔의 spot size를 줄이고자 하는 연구는 현재도 전세계적으로 활발히 이루어지고 있고 이러한 노력의 일환으로 어느 정도의 추가적인 저장용량 증가는 가능할 수 있으나, 2차원 방식으로는 대용량 광정보기록 (수백 GB ${\sim}$ TB급)의 실현은 불가능하다는 것이 일반적인 예상이다. 한편 장기적으로 기존의 2차원 정보기록방식을 대체하고 저장용량을 획기적으로 증가시킬 수 있는 bit-type 3차원 광정보기록의 개념이 1990년을 전.후로 처음으로 제시되었다. 이는 2차원 bit 정보가 수십 내지 수백 개의 다층 (multi-layer) 형태로 기록되는 방식인데, 그동안 산업체의 관심이 상대적으로 높지 않았던 이유는 영화, 음악 등 엔터테인먼트 시장성 확대를 위해 Blu-ray disc나 HD-DVD에 대한 연구개발에 치중해왔기 때문이다. 하지만 최근 급변하는 정보시스템 서비스 환경 속에서 정보유통량이 기하급수적으로 증가하고 있고 개인이 취급하는 정보량도 2010년경에는 수백 GB 단위가 될 것으로 예상되고 있으며 디지털 방송, 네트워크를 기반으로 한 서비스 수요 뿐 만 아니라 전자도서관이나 VOD (Video on Demand) 서비스 사업에 필수적인 수 TB급의 대용량 저장장치에 대한 수요 또한 크게 증가할 것으로 전망된다. 이에 따라 점차 그 물리적 한계에 다다르고 있는 기존의2차원 정보저장방식을 대체하고 저장용량을 획기적으로 증가시킬 수 있는3차원 정보기록(> $10^{13}$ $bits/cm^3$)에 대한 필요성이 대두된다.

• Journal of Korean Society of Water and Wastewater
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• v.32 no.4
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• pp.357-361
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• 2018

Forward osmosis (FO) process has been attracting attention for its potential applications such as industrial wastewater treatment, wastewater reclamation and seawater desalination. Particularly, in terms of fouling reversibility and operating energy consumption, the FO process is assumed to be preferable to the reverse osmosis (RO) process. Despite these advantages, there is a difficulty in the empirical step due to the lack of separation and recovery techniques of the draw solution. Therefore, rather than using FO alone, recent developments of the FO process have adapted a hybrid system without draw solution separation/recovery systems, such as the FO-RO osmotic dilution system. In this study, we investigated the performance of the hollow fiber FO module according to various operating conditions. The change of permeate flow rate according to the flow rates of the draw and feed solutions in the process operation is a factor that increases the permeate flow rate, one of the performance factors in the positive osmosis process. Our results reveal that flow rates of draw and feed solutions affect the membrane performance, such as the water flux and the reverse solute flux. Moreover, use of hydraulic pressure on the feed side was shown to yield slightly higher flux than the case without applied pressure. Thus, optimizing the operating conditions is important in the hollow fiber FO system.

• Journal of Electrochemical Science and Technology
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• v.3 no.1
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• pp.29-34
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• 2012

The structural changes of $Li_{1-x}Ni_{0.5}Co_{0.2}Mn_{0.3}O_2$ cathode material for lithium ion battery during the first charge was investigated in comparison with $Li_{1-x}Ni_{0.8}Co_{0.15}Al_{0.05}O_2$ using a synchrotron based in situ X-ray diffraction technique. The structural changes of these two cathode materials show similar trend during first charge: an expansion along the c-axis of the unit cell with contractions along the a- and b-axis during the early stage of charge and a major contraction along the c-axis with slight expansions along the a- and b-axis near the end of charge at high voltage limit. In $Li_{1-x}Ni_{0.5}Co_{0.2}Mn_{0.3}O_2$ cathode, however, the initial unit cell volume of H2 phase is bigger than that of H1 phase since the c-axis undergo large expansion while a- and b- axis shrink slightly. The change in the unit cell volume for $Li_{1-x}Ni_{0.5}Co_{0.2}Mn_{0.3}O_2$ during charge is smaller than that of $Li_{1-x}Ni_{0.8}Co_{0.15}Al_{0.05}O_2$. This smaller change in unit cell volume may give the $Li_{1-x}Ni_{0.5}Co_{0.2}Mn_{0.3}O_2$ cathode material a better structural reversibility for a long cycling life.

• Journal of the Korean Chemical Society
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• v.33 no.4
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• pp.399-405
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• 1989

The dependence of voltammetric parameters on the pressure for the reduction of Cu(II) in 0.5M KCl aqueous solution has been studied. In this system micro platinum electrode, standard calomel electrode and a helix type of platinum wire were used as the working, the reference and the auxilary electrode, respectively. With increasing the pressure from 1 to 1,800 bars, the half wave potentials of first reduction wave are shifted to the more negative potentials. And the diffusion currents of first and second reduction wave become considerably larger with increase in pressure from 1 to about 1,000 bars but are getting smaller beyond 1,000 bars. The good linear relationships between diffusion current and the concentrations of Cu(II) are established over all pressure range($1{\sim}1,800$ bars). The reversibility of the each reduction step is not changed with increasing pressure.

• 보존과학연구
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• s.30
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• pp.63-77
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• 2009

Scientific studies of conservation techniques and materials in Korea have experienced fast development since international practice and academic knowledge have been introduced to Korea from Japan, France, Germany, and etc from the late 1960s. In recent years, it has been observed that the academic standard of research and the level knowledge of the field in Korea at present are far advanced to compete with many countries. However, many Korean cases still have displayed that the standard and the quality of conservation practice need to be improved. This research examined several cases of derelict restoration of metal relics executed by non-conservators and the effects of their ignorant use of irreversible materials on the valuable objects. The purpose of the study is to display the problem of such treatments and to suggest a need of framework to prevent the loss of original form from them. Metal Buddha statue (Cosmic Buddha) in Borim Temple (National Treasure No. 117), which was conserved by an unexperienced non-conservator, has suffered from a serious problem of corrosion because of the use of destructive material, iron chloride. Another case for metal Buddha statue in Dopian Temple (National Treasure No. 63) displays a representative example of using irreversible materials, Cashew and such ignorant application made a later conservation treatment so difficult in removing the material from the surface of the statue. In conclusion, the research argued that the understanding of materials used in the objects, and the value of relics is important, and pre-experiments before applying conservation materials to a valuable heritage are essential in the conservation treatment.