• Title/Summary/Keyword: reverse profile

Search Result 139, Processing Time 0.028 seconds

A Study on Vortical Flow Patterns of a Heaving Foil (히빙익 후류의 유통패턴에 관한 연구)

  • Yang, Chang-Jo;Kim, You-Taek;Choi, Min-Seon;Lee, Young-Ho
    • Proceedings of the Korean Society of Marine Engineers Conference
    • /
    • 2005.11a
    • /
    • pp.31-32
    • /
    • 2005
  • It is known that an oscillating airfoil can produce a driving force through the generation of a reversed $K\acute{a}rm\acute{a}n$ vortex street, and this can be expected to be a new highly effective propulsion system. We have been examined various conditions such as frequency number, amplitude in NACA 0010. As Strouhal number is greater than 0.08, wake profile with velocity deficit can be transformed into the wake with velocity excess. We also presented the experimental results on the unsteady vortices structure of the heaving airfoil at various parameters.

  • PDF

An RNA Mapping Strategy to Identify Ribozyme-Accessible Sites on the Catalytic Subunit of Mouse Telomerase

  • Song, Min-Sun;Lee, Seong-Wook
    • Genomics & Informatics
    • /
    • v.5 no.1
    • /
    • pp.32-35
    • /
    • 2007
  • Telomerase reverse transcriptase (TERT) is an enzymatic ribonucleoprotein that prolongs the replicative life span of cells by maintaining protective structures at the ends of eukaryotic chromosomes. Telomerase activity is highly up-regulated in 85-90% of human cancers, and is predominately regulated by hTERT expression. In contrast, most normal somatic tissues in humans express low or undetectable levels of telomerase activity. This expression profile identifies TERT as a potential anticancer target. By using an RNA mapping strategy based on a trans-splicing ribozyme library, we identified the regions of mouse TERT (mTERT) RNA that were accessible to ribozymes. We found that particularly accessible sites were present downstream of the AUG start codon. This mTERTspecific ribozyme will be useful for validation of the RNA replacement as cancer gene therapy approach in mouse model with syngeneic tumors.

Plane Strain Analysis of Sheet Metal with Arbitrary Forming Conditions (임의의 성형조건을 갖는 박판의 평면변형율 해석)

  • Keum, Y.T.;Lee, S.Y.;Wagoner, R.H.
    • Transactions of Materials Processing
    • /
    • v.1 no.1
    • /
    • pp.95-103
    • /
    • 1992
  • The plane strain analysis for simulating the stretch/draw forming operation with an arbitrarily-shaped tool profile is introduced. An implicit, incremental, updated Lagrangian formulation with a rigid-viscoplastic constitutive equation is employed. Contact and friction are considered through the mesh-normal, which compatibly describes arbitrary tool surfaces and FEM meshes without depending on the explicit spatial derivatives of tool surfaces. The linear line elements are used for depicting the formed sheet, based on membrane approximation. The FEM formulation is tested in the sections of automotive inner panel and two-side draw-in. Not only the excellent agreement between measured and computed strains is obtained in the stretched section, but also the numerical stability of formulation is verified in the draw-in section.

  • PDF

Several Genes Expressed During Morphogenesis of Lentinus edodes(ImHyup-1)

  • Lee, Sang-Sun;Hong, Sung-Woon;Kim, Seung-Hae;Kim, Bong-Cheol
    • Mycobiology
    • /
    • v.29 no.3
    • /
    • pp.135-141
    • /
    • 2001
  • Differential display of reverse transcription(DDRT)-PCR was conducted to have a profile of the differentially expressed genes during the formation of fruiting body of Lentinus edodes. The lines of L. edodes(ImHyup-1) employed were cultivated in the artificial blocks of sawdust, and the fruiting body was induced from the mycelia or the mass protruded from the brown surface of the sawdust blocks. RNAs were prepared from the four different developmental stages; mycelial, primordial, and stipes and pileus of fruiting body. The fragments of cDNA were synthesized from the combinations of the arbitrary primers and 3' one anchored Oligo-dT primer. Twelve combinations using the primers have been tested, and among them nineteen bands were identified as differentially expressed. Those genes were further analyzed by DNA sequencing and followed by homology search. Characterization of one clone was conducted as a preliminary data and more are under investigation.

  • PDF

A Retrospection on Foundation Design of Taipei 101

  • Chin, Chung-Tien;Chao, Hsiao-Chou;Chang, Der-Wen
    • Proceedings of the Korean Geotechical Society Conference
    • /
    • 2009.09a
    • /
    • pp.145-156
    • /
    • 2009
  • Large diameter bored pile was selected as the foundation type for Taipei 101. The pile construction method and specific construction procedures were determined based on the results of trial installation and pile load tests. The baseline for foundation design was established using the friction versus depth characteristics of each ground layer obtained from the pile load tests. As the ground profile and depth to the top of rock formation varied significantly on this site, the pile length, bearing capacity and settlement for single pile were analyzed using the information interpreted from adjacent boreholes. The post grouting at pile tip was mandatory for pile construction. Nevertheless, it was treated as a measure reducing the influence of construction uncertainties and providing extra safety for the foundation system.

  • PDF

A Random Amplified Polymorphic DNA (RAPD) primer to assist the Identification of Panax ginseng in Commercial Ginseng Granule Products

  • Shim, Young-Hoon;Choi, Jung-Ho;Park, Chan-Dong;Lim, Chul-Joo;Kim, Do-Hun;Cho, Jung-Hee;Kim, Hong-Jin
    • Proceedings of the PSK Conference
    • /
    • 2003.10b
    • /
    • pp.85.1-85.1
    • /
    • 2003
  • Previously, we found the operon random primer (OP-5A) that is characteristic the genus Panax by randomly amplified polymorphic DNA (RAPD) analysis. However, OP-5A primer is limited to apply on the differentiation of only crude herbal plants. To construct more sensitive and unique primers on the genus Panax, ginseng-specific DNA profile (350 bp) that was amplified by OP-5A primer were inserted in a plasmid vector in the TA cloning method and sequenced. We designed the PCR primers (Forward: 5"-AGGGGTCTTGCTAT AGCGGAAC-3", Reverse: 5"-AGTCTTAATTTCATATTTTCGTATG-3") and identified the unique ginseng band (350 bp) in commercial granule products including ginseng extracts as well as crude ginseng plants by nascent PCR.(omitted)

  • PDF

Bioavailability of Clonazepam in human plasma using a simple HPLC

  • Lee, Dong-Kyu;Jeong, Ji-Hoon;Park, Joon-Hong;You, Dae-Sik;Sohn, Uy-Dong
    • Proceedings of the PSK Conference
    • /
    • 2003.10b
    • /
    • pp.244.1-244.1
    • /
    • 2003
  • We aimed at determining bioavailability of clonazepam, an anxiolytic drug, and developing a simple analysis in human blood using HPLC. A rapid and sensitive HPLC method was developed and validated using reverse-phase C18 column with retension time and limit of quantification of clonazepam being 2.58 min and 5hg/ml, respectively. Quantification was performed at 235 nm with p-hydroxybenzoic acid ethyl ester as internal standard. The method involved a simple extraction. In order to study blood level profile in time, sight volunteers were enrolled and orally took 6 mg clonazepam once. (omitted)

  • PDF

Bioavailability of Procainamide HCl in human plasma using a simple HPLC

  • Park, Joon-Hong;Jeong, Ji-Hoon;Choi, Tae-Sik;Lee, Dong-Kyu;Shim, Jae-Ho;Sohn, Uy-Dong
    • Proceedings of the PSK Conference
    • /
    • 2003.10b
    • /
    • pp.240.2-240.2
    • /
    • 2003
  • We aimed at determining bioavailability of procainarnide HCl, an antiarrhythmic drug, and developing a simple analysis in human blood using HPLC. A rapid and sensitive HPLC method was developed and validated using reverse-phase C18 column with retension time and limit of quantification of procainamide HCl being 2.58 min and 50ng/ml, respectively. Quantification was performed at 275 nm with caffeine as internal standard. The method involved a simple extraction. In order to study blood level profile in time, eight volunteers were enrolled and orally took 250 mg procainamide HCl once. (omitted)

  • PDF

EFFECTS OF Si, Ge PRE-IMPLANT INDUCED DEFECTS ON ELECTRICAL PROPERTIES OF P+-N JUNCTIONS DURING RAPID THERMAL ANNEALING

  • Kim. K.I.;Kwon, Y.K.;Cho, W.J.;Kuwano, H.
    • Journal of the Korean Vacuum Society
    • /
    • v.4 no.S2
    • /
    • pp.90-94
    • /
    • 1995
  • Defects introduced by Si, Ge preamorphization and their effects on the dopant diffusion and electrical characteristics. Good crystalline quality are obtained after the annealing of Ge ion double implanted samples. The defect clusters under the a/c interface are expected to extend up to the deep in the Si ion implanted samples. The dislocation loops near the junction absorb the interstitial Si atoms resolving from the defect cluster and result in the prevention of enhanced boron diffusion near the tail region of boron profile and show good reverse current charactristics.

  • PDF

Capacity of synchronous DS-CDMA system on frequency selective multipath fading channels with imperfect power control (주파수 선택적 다중 경로 페이딩 채널에서 불완전 전력 제어를 고려한 동기식 DS-CDMA 시스템의 수용 용량)

  • 황승훈;김용석;김동희;황금찬
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.25 no.3A
    • /
    • pp.342-350
    • /
    • 2000
  • In this paper, the bit error performance for the reverse link of a synchronous direct sequence code division multiple access (DS-CDMA) system employing an imperfect power control scheme over a frequency selective Rayleigh fading channel is analyzed. The system capacity degradation due to power control error (PCE), which is approximated by a log-normally distributed random variable, is estimate as a function of a standard deviation of the PCE. In addition, the impact of the multipath intensity profile (MIP) shape and the number of resolvable paths on the performance of the synchronous transmission is investigated. To estimate the system capacity, the coded bit error performance is evaluated and compared with the conventional CDMA. It is found tat synchronous transmission has less sensitivity to imperfect power control and eases the power control requirements. In particular, as the decay constant $\delta$ of MIP increases, the synchronous transmission in the DS-CDMA reverse link results in a significant BER improvement over the asynchronous transmission even in the presence of imperfect power control. We further conclude that the capacity can be improved by employing the synchronous transmission.

  • PDF