• Journal of Pharmaceutical Investigation
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• 제35권5호
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• pp.333-336
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• 2005

The objective of this study was to investigate the stability of tetracycline HCl on encapsulation into and inside reverse micelles. To do so, tetracycline HCl was first mixed with cetyltrimethylammonium bromide, water and ethyl formate to make reverse micelles. The degradation kinetics of tetracycline HCl inside the reverse micelles was then assessed by scrutinizing its stability data. Under our experimental conditions, the reverse micelles formed spontaneously in absence of any mixing devices. During the preparation of the reverse micelles, however, considerable portions of tetracycline HCl underwent a chemical reaction (e.g., epimerization). For instance, $51.4{\pm}0.6%$ of an initial concentration of tetracycline HCl was transformed into a degradation product. Once dissolved inside the reverse micelles, the degradation of tetracycline HCl followed an exponential decay pattern. The plot of log{the degradation rate of tetracycline HCl} versus log{tetracycline HCl concentration} made it possible to determine the order of degradation reaction and rate constant. It was proven that the degradation of tetracycline HCl inside the reverse micelles followed a first order kinetics with a rate constant of 0.0027 $hour^{-1}$. Meriting further investigation might be formulation studies to stabilize tetracycline HCl on encapsulation into and inside the reverse micelles.

• 대한산업공학회지
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• 제40권2호
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• pp.205-214
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• 2014

As a result of the rapid economic growth and birth control policy, China is experiencing low fertility rates and increasing life expectancy, which makes Chinese population aging very quickly and unprepared for their retired life. The reverse mortgage may be an attractive option for the elderly because it is a loan against a house that they do not have to pay back as long as they live there. In this paper, in order to introduce the reverse mortgage scheme in China the factors that could influence the demand of reverse mortgage are reviewed and the Chinese market environment is analyzed. Then the principal component analysis is performed in order to recommend the regions or cities that have higher potential for successful implementation of a reverse mortgage than any other ones in China.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2010년도 정기 학술대회
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• pp.268-271
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• 2010

In this paper, forward and reverse analysis is introduced in order to estimate the elastic-plastic properties from a power-law hardening bulk specimen materials with one simple spherical indentation impression test. In order to verify the reliability of the reverse analysis, we have simulated about a large range of materials that essentially cover all engineering materials, using ABAQUS(6.91) program. Then, we could obtained the fitting functions and plastic parameters from the numerical analysis results. Next, through the procedure of reverse analysis we can obtain the yield stress and power-law exponent. Finally, obtain good agreement between the result from reverse analysis and initial input data from experiment.

• Journal of the Korean Data and Information Science Society
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• 제10권1호
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• pp.243-250
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• 1999

We consider $Y=X{\lambda}Z,\;{\lambda}>0$, where X and Z are independent random variables, and Y is the length biased distribution or the equilibrium distribution of X. The purpose of this paper is to consider the distribution of X or Y when the distribution of Z is given and the distribution of Z when the distribution of X or Y is given, In particular, we obtain that the necessary and sufficient conditions for X to be $X^{2}({\upsilon})\;is\;Z{\sim}X^{2}(2)\;and\;for\;Z\;to\;be\;X^{2}(1)\;is\;X{\sim}IG({\mu},\;{\mu}^{2}/{\lambda})$, where $IG({\mu},\;{\mu}^{2}/{\lambda})$ is two-parameter inverse Gaussian distribution. Also we show that X is smaller than Y in the reverse Laplace transform ratio order if and only if $X_{e}$ is smaller than $Y_{e}$ in the Laplace transform ratio order. Finally, we can get the results that if X is smaller than Y in the Laplace transform ratio order, then $Y_{L}$ is smaller than $X_{L}$ in the Laplace transform order, and that if X is smaller than Y in the reverse Laplace transform ratio order, then $_{\mu}X_{L}$ is smaller than $_{\nu}Y_{L}$ in the Laplace transform order.

• Journal of Ginseng Research
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• 제19권2호
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• pp.101-107
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• 1995

The present study was undertaken to examine the effects of ginseng saponins [ginseng total saponin (GTS), protopanaxadiol saponin (PD) and protopanaxatriol saponin (PT)] on the hyperactivity, reverse tolerance and dopamine receptor super-sensitivity induced by cocaine. A single treatment with cocaine produced hyperactivity. Repeated administration of cocaine developed reverse tolerance and dopamine receptor super-sensitivity was also developed in reverse tolerant mice which had received the same cocaine. The hyperactivity and the developments of reverse tolerance and dopamine receptor super-sensitivity by cocaine were inhibited by ginseng saponins. From these results, it is proposed that ginseng saponins may be useful for the prevention and therapy of the adverse actions of cocaine. In addition, the rank order of inhibitory potential was observed as PT>GTS>PD. Key words Cocaine, hyperactivity, reverse tolerance, dopamine receptor super-sensitivity, ginseng saponins.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제8권11호
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• pp.3896-3915
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• 2014

The Reverse k Nearest Neighbor (RkNN) query is valuable for finding objects influenced by a specific object and is widely used in both scientific and commercial systems. However, the influence level of each object is unknown, information that is critical for some applications (e.g. target marketing). In this paper, we propose a new query type, Ordered Reverse k Nearest Neighbor (ORkNN), and make efforts to adapt it in an on-demand scenario. An Order-k Voronoi diagram based approach is used to answer ORkNN queries. In particular, for different values of k, we pre-construct only one Voronoi diagram. Algorithms on both the server and the clients are presented. We also present experimental results that suggest our proposed algorithms may have practical applications.

• Archives of Reconstructive Microsurgery
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• 제10권1호
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• pp.55-59
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• 2001

The hand is a frequently affected area in high voltage electrical burn injury as an input or output sites. Therefore, early debridement and synchronous flap coverage are generally accepted as a primary treatment of several electrical burns complicated by exposure of tendons, neurovascular structures, and bones. So, in order to establish convenient, promising methods for the reconstruction of hand defects in electrical burn patients, we performed various reverse forearm flaps. From March 1997 to February 2000, we reconstructed 12 cases of hand defects in high voltage electrical burn wounds with reverse forearm flaps. Reverse radial fasciocutaneous flap were 3 cases, reverse ulnar fasciocutaneous flap were 3 cases, reverse ulnar fasciocutaneous flap and STSG were 4 cases, reverse ulnar fascial flap and STSG were 2 cases. We successfully reconstructed hand defects in all 12 cases, and obtained following conclusions. 1 Various reverse forearm flaps provide well vascularized, profitable tissues and they require short operative time with relatively easy procedures. 2. Reverse fascial flap and STSG, reverse fasciocutaneous flap and STSG provide thin flaps with good aesthetics and minor donor site morbidity.

• 대한안전경영과학회지
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• 제10권1호
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• pp.129-137
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• 2008

The studies on the logistics has been mainly centered on the logistics information system and logistics performance on the supply chain for the enterprise's profit making. For sustainable development, it's being required the construction of recycling-oriented system, and it's also necessary to construct the efficient system not only in forward but in reverse channel. In addition, it's required to construct information system for supporting reverse logistics smoothly. In this study of manufacturing enterprises, recognition on the environmental problems is set as the adaptation degree to the national environmental regulations and enterprise's concern to the environmental logistics, and it presents the direction through analyzing the effects of such environmental logistics recognition on reverse logistics information system and performance. In order to achieve these aims, it was performed through combining philological and positive studies.

• Industrial Engineering and Management Systems
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• 제12권2호
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• pp.161-170
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• 2013

Deployment of green transportation in reverse logistics is a key issue for low carbon technologies. To cope with such logistic innovation, this paper proposes a hybrid approach to solve practical vehicle routing problem (VRP) of pickup type that is common when considering the reverse logistics. Noticing that transportation cost depends not only on distance traveled but also on weight loaded, we propose a hierarchical procedure that can design an economically efficient reverse logistics network even when the scale of the problem becomes very large. Since environmental concerns are of growing importance in the reverse logistics field, we need to reveal some prospects that can reduce $CO_2$ emissions from the economically optimized VRP in the same framework. In order to cope with manifold circumstances, the above idea has been deployed by extending the Weber model to the generalized Weber model and to the case with an intermediate destination. Numerical experiments are carried out to validate the effectiveness of the proposed approach and to explore the prospects for future green reverse logistics.

• 한국경영과학회:학술대회논문집
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• 한국경영과학회 2004년도 추계학술대회 및 정기총회
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• pp.565-565
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• 2004

Due to limitation of resources and increasing concerns about environment, reverse logistics has received growing attention in recent years. In this paper, we propose three types of reverse logistics networks based on reuse of returnable containers, materials recycling process and remanufacturing for parts reuse. First, the sender in the re-usable item network supplies containers for the recipient and orders either new containers from external supplier or returnable containers cleaned from the container depot. Second, the recycling center in the proposed recycling network collects either end of life products from customer or faulty goods from manufacturer, collected products are dismantled into materials and materials go into recycling process. Finally, the manufacturer in the proposed remanufacturing network has two alternatives for supplying parts: either ordering the required parts to external supplier or overhauling disassembled parts and bringing them back 'as new' conditions. In this product recovery environment, we build optimal order quantity models to minimize the total logistics costs related to reverse logistics network. The validity of the proposed model is investigated through comprehensive computational experiments.