• Journal of Oral Medicine and Pain
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• v.31 no.1
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• pp.79-89
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• 2006

The aim of this study is to know how the rat submandibular gland changes under various emotional stress condition, using molecular biological methods. Restraint and chronic unpredictable mild stress (CUMS) experiment is conducted on fifty one 7-week old Sprague-Dawley rats (restraint stress experiment: 21, CUMS: 30). The rats were sacrificed, the submandibular glands were excised immediately at certain time, and examined by the use of immunohistochemistry and western blotting. In CUMS experiment, sucrose preference test, water intake change, weight change were implemented at 1 week interval for the experimental period The results are as follows: 1. The number of clusterin-secreting cells of restraint stress group compared to control group showed significantly decreasing tendency in all experimental groups except for the 1st hour group (p<0.001 in the 9th, 24th, 72nd, 120th, and 168th hour group). 2. The number of clusterin-secreting cells of CUMS group compared to control group showed significantly increasing tendency in the 2nd week group (p<0.01), and significantly decreasing tendency in the 4th and 5th week group (p<0.001). 3. Sucrose preference test in CUMS experiment showed significant difference between the 5th week experimental group and control group (p<0.01). 4. Weight change in CUMS experiment showed significant difference between the 5th week experimental group and control group (p<0.01), but water intake change didn't show significant difference compared to control group. 5. In western blot analysis, clusterin expression was decreased on a gradual basis in due time compared to the control group in the restraint stress group. As for CUMS group (chronic unpredictable mild stress group), it was increased till the 2nd week and decreased till the 5th week after that, which is similar to immunohistochemical analysis result and the decreasing tendency of sucrose preference and weigh changes. Through the test, it was proved that expression of clusterin in saliva glands decreases after receiving either acute or chronic stress, indicating relation with depression caused by chronic stress. Unlike other data, however, apoptotic tendency was hardly found in tissues. Diverse possibilities could be suggested on that: first, the stress was not enough to expedite apoptosis; second, apoptosis-related protein was already being secreted though not detected with microscope; third, clusterin, a major secretion molecule of saliva, decreased with saliva's malfunction due to stress. In the respect, it will be necessary to examine proteins expressed in case of cell death or other heat-shock proteins at the same time, in order to see whether any cellular change or death is caused by decreasing clusterin under high stress, and whether the original state is restored as time goes by under mild stress, through longer-term tests using even higher acute stress.

• Journal of Nutrition and Health
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• v.55 no.3
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• pp.376-389
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• 2022

Purpose: Obesity can lead to several chronic diseases. With a continuous increase in the obesity rates, sustainable healthy weight management among growing adolescents has become essential. This study was conducted to examine the relationship between obesity-related factors and creative convergence ability. This could form the basis for convergence education for the sustainable healthy weight management of adolescents. Methods: Data were collected from 430 adolescents in Daegu, Gyeongbuk, and Gyeonggi regions using a self-administered 5-Likert questionnaire from November to December 2020. Results: The average score of the male students was higher than that of the female students in terms of healthy weight management convergence awareness, creativity, convergence thinking ability, self-efficacy, exercise, and dietary diversity. On the other hand, the dietary restraint score and the number of weight loss attempts were higher in the female students. Dietary restraint, disinhibition scores and weight loss attempts were higher in obese adolescents compared to underweight adolescents. It was found that dietary restraint, convergence thinking ability, problem-solving ability, exercise, and dietary diversity factors had a positive effect on healthy weight management convergence awareness. Healthy weight management convergence awareness, exercise, meal amount management, junk food management, weight loss belief, and weight loss trial experience had a positive effect on dietary restraint. Convergence thinking ability, weight loss experience, and obesity factors had a positive effect on dietary disinhibition. Conclusion: The sustainable healthy weight management education of adolescents is based on weight management knowledge and awareness of convergence, and must include gender differences. Thus, the problem-solving ability for healthy weight management can be creatively cultivated to enhance self-efficacy.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2007.05a
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• pp.431-433
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• 2007

The drawbeads, which is used for controlling the flow of the sheet by imposing the tension and for preventing the springback in the sheet metal forming process, affects a lot the formability because of the differences in the restraint and opening forces according to the drawbead shapes and dimensions. In this study, the experimental device enabling to measure the drawbead restraining and opening forces was manufactured and the drawing forces of circular, square, and step drawbeads are measured. The drawbead restraining and opening forces of a circular drawbead are increased as its drawbead height is increased. Similarly, those of a square drawbead are increased as its height is increased and shoulder radii decreased. Also, those of a step drawbead are increased as its height and difference in their heights are increased.

• Korean Institute of Interior Design Journal
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• no.28
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• pp.17-24
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• 2001

This study aims at the spatial analysis in semiotic architecture focusing on the early works of M. Graves and P. Eisenman, the representative architects of semiotic architecture. This study on the semiotics of architectural space can be started with literaeur's approaches which recognizes it as the language. Thus, to applicate semiotics in architectural space means a methodology reaching for essential architecture. The conclusions of the study as per the above mentioned aims and intentions are as follows: The viewpoint of spatial analysis in M. Graves's semiotic architecture is defined the semantic metaphorical space of denotative context : That of P. Eisenman's described the synthetic deep of connotative self-restraint.

• Proceedings of the Korean Geotechical Society Conference
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• 1999.03a
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• pp.177-184
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• 1999

In soft ground tunneling, shield method is very good for safety of neighboring structures. Although shield tunnel method has the merits to minimize the deformation of ground around tunnel, ground deformations occurred until the material grouted in tail void hardens are inevitable. In this study, the effects of micropile used as one method to restrain the settlement of neighboring structures by the tail void are studied by laboratory model tests. As a basic test result, the effective direction of micropile and the restraint rate of settlement by micropile reinforcement are known.

• Journal of the Speleological Society of Korea
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• no.77
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• pp.9-19
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• 2007

동굴 내에서 조명으로 인한 생태환경 변화를 억제할 수 있는 방안에 관하여 조사하였다. 어두운 동굴이 인간의 필요에 따라 개방되고, 개방된 동굴은 조명시설에 의해 내부가 밝혀진다. 이 과정에서 동굴생태 변화가 발생하고, 특히 녹색광합성에 의한 식물 개체가 생성된다. 따라서 본래의 동굴생태가 변화되는 환경이 만들어지는데, 이들 자연자원의 환경은 보존되어야 함으로 생태환경의 변화는 억제되어야 한다. 이를 위하여 발광다이오드의 냉광원을 사용하여 선택파장광원에 의한 광합성 억제작용 방안을 제시하였다. 식물의 녹색광합성을 위한 흡수광파장이 460nm와 680nm 부근임으로 이들 흡수파장을 제외한 밝은 빛 파장 즉, 550nm 근처의 황색 및 황록색 파장 빛을 써서 동굴조명을 하면, 녹색광합성 및 식물개체의 생성과 성장을 억제할 수 있다.

• Asian Journal of Innovation and Policy
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• v.4 no.1
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• pp.19-34
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• 2015

Silicon Valley's legal foundation in recent years has surfaced on the radar of policy planners who model Silicon Valley's information and communication technologies (ICT) industry. Precisely, the prohibition of covenants not to compete (CNCs) is linked to firm-to-firm knowledge spillovers by way of mobile workers positioned as nodes in a system of innovation. Meanwhile, traditional frameworks support enforcement of CNCs as a way to encourage R&D activities to the worker and to prevent the worker's tacit knowledge and know-how from fleeing. Amidst the battle for the restraint or release of human capital, we present an industrial approach to reconcile the ostensible strife between enforcement and prohibition frameworks. Theoretically, we contend an industrial approach can maximize the policy tools of discorded planners. Moreover, this article newly compares the ICT industries of Silicon Valley and Route 128 to argue that California's law is a unique factor in the greater success of Silicon Valley firms.

• Steel and Composite Structures
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• v.18 no.1
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• pp.135-148
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• 2015

The cutout hole locating at the place of rib-to-diaphragm welded connection is adopted to minimize the restraint, which is caused by the floor-beam web to rib rotation at the support due to the unsymmetrical loads in orthotropic deck. In practice, an inevitable problem is that there is a large number of welding joint's cracks formed at the edge of cutout hole. In this study, a comparative experiment is carried out with two types of cutout hole, the circular arc transition and the vertical transition. The fatigue life estimation of specimens is investigated with the application of the structural hot spot stress approach by finite element analyses. The results are compared with the ones of the fatigue tests which are carried out on these full-scale specimens. Factors affecting the stress range are also studied.

• Journal of the Society of Disaster Information
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• v.4 no.1
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• pp.138-152
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• 2008

The most important factor in the maintenance of chemical industry facilities is related with deterioration and corrosion. Leakage of hazardous materials is likely to occur because the confirmation and maintenance of bottom plates are very difficult while the bottom corrosion of the massive hazmat-storage facilities is most dangerous especially. As a result of the analysis of the corrosion locations, areas, usage condition of 287 hazmat-storage tanks on this syudy, it is concluded that the main external corrosion factors are the inflow of moisture and the materials inducing corrosion in the air such as sodium chloride and the main internal corrosion factors are corrosion react caused by stay of seawater, sulfur and moisture in hazmat for a long time without appropriate discharges. It is anticipated that the corrosion of bottom plates can be restrained effectively by establishing the proper measures for the each corrosion cause.

• Korean Journal of Veterinary Research
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• v.21 no.2
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• pp.145-150
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• 1981

This study was performed to evaluate the sedative effect of xylazine for restraint of deers such as sika deer (19 cases), red deer (19 cases), elk (19 cases), pere david deer (13 cases) and reindeer (8 cases), raised in the area of surburb of Seoul, Chungcheongnam-do and Gyungsangbug-do. provinces The results were as follows : 1. The more the dose of xylazine, the earlier the onset of sedation, and the s1ower the recovery time to normal state. 2. The optimal intramuscular dose of xylazine was found to be 0.8~1.4mg per Kg of body weight for sika deer, 0.6~1.0mg for red deer, 1.0~1.4mg for elk, 0.2~0.4mg for pere david deer, and 0.6~1.0mg for reindeer.