• 정보보호학회논문지
• /
• 제25권1호
• /
• pp.133-146
• /
• 2015

전자금융사기의 고도화와 함께 지능적인 수법들이 동원됨에 따라 전자금융 사용자들의 피해사례가 늘어나고 있다. 이에 대한 대응 방안으로 금융당국은 사용자 구간에 집중된 기존 보안 대책 외에 이의 한계성을 극복하기 위한 이상거래 탐지 시스템의 도입을 확대 권고하고 있다. 이상거래 탐지 시스템은 실시간으로 고객의 거래를 확인하고 이상거래 유무를 판별하여 전자금융 사고를 방지할 수 있도록 하는 시스템으로 거래 정보를 빠르게 분석하여 이상거래를 식별하는 것이 핵심이다. 본 논문에서는 사고 데이터분석을 통해 이상 징후 패턴을 파악하고 탐지 룰을 설정하고, 이렇게 설정된 룰을 기반으로 고객 개인별 거래 패턴과 고객 프로파일을 비교하여 이상거래 여부를 판단하고자 한다. 이때 의사결정나무를 사용하여 탐지 룰을 정규화 하여 효과적으로 이상거래를 탐지 할 수 있도록 하는 방법을 제안하고자 한다. 실증 분석을 위해 국내 모 은행의 전자금융 사고 데이터를 바탕으로 패턴 정보와 고객 프로파일 정보를 도출하였고 이를 통하여 탐지 룰을 설정하였다. 그리고 탐지된 룰을 의사결정나무를 사용하여 정규화 한 결과를 순차적인 탐지 방식과 비교하여 제시된 방안이 효과적임을 확인하였다.

• 대한물리치료과학회지
• /
• 제8권2호
• /
• pp.977-987
• /
• 2001

The purpose of this study was to examine the effects of sensory integration therapy (SIT) on sensory' motor development and adaptive behavior of cerebral palsy children. The design of this study was quasi experiments with a non-equivalent pre- and post-test control design. Subjects of the study were arbitrarily chosen based on predetermined selection criteria among the cerebral palsy children who were treated as out-patients at two rehabilitation hospitals one in Seoul, and the other in Kyunggi-do. The study was conducted between early April and late July in 2000. Fifteen children were in the experimental group and eleven in the control group. The allocation was done based on ease of experimental treatment. A five-step SIT program was devised from a combination of SIT programs suggested by Ayres(1985) and Finks(1989), and an author-designed SIT program for cerebral palsy children. The experimental group was subjected to 20 to 30 minutes of SIT per session. two sessions a week for ten -week period. The effects of SIT were measured with respect to 9 sub-areas that can be administered to cerebral palsy children out of a total of 17 sub-areas in the Southern California Sensory Integration Test (SCSIT) developed by Ayres (1980). In addition. the scale developed by Russell (1993) for Gross Motor Function Measure (GMFM). and Perception Motor Development Test developed by 中司利一 et al.(1987) were also applied. Adaptive behavior was analyzed using guidelines in two unpublished documents - School-Age Checklist for Occupational Therapy by the Wakefield Occupational Therapy Associates, and the OTA-Watertown Clinical Assessment by the Watertown Occupational Therapy Associates-, and an author-developed Adaptive Behavior Checklist. Collected data were statistically analyzed by SPSS PC for chi square test, Mann-Whitney test, Wilcoxon signed rank test, and paired t-test. The results were as follows: 1. In sensory development, the experimental group exhibited a score increase compared to the control group, but the difference was not statistically significant, Although the experimental group showed improvements in all. 9 sub-areas compared to the control group, only right-left discrimination exhibited statistically significant change. 2. In gross motor development, the experimental group showed improvements in score compared to the control group, but it was not statistically significant. In fine motor development, the experimental group exhibited statistically significant improvements compared to the control group. In sub-area analysis, figure synthesis showed positive change. 3. In adaptive behavior development, post-experimental adaptive behavior scores were higher compared to pre-experimental scores with statistical significance. Furthermore, sub-areas emotional behavior, perception behavior, gross-fine motor function, oral-respiration function, motor behavior, motor planning, and adaptive response exhibited higher scores after SIT. In conclusion SIT was found to be partially effective in sensory and fine motor development, effective in all adaptive behavior areas, and not effective in gross motor development. Thus, this study has shown that SIT is an effective intervention for sensory development, fine motor development, and adaptive behavior for cerebral palsy children. But, for the effectiveness of SIT on gross motor development, further studies employing longer-time experiments are recommended.

• Reproductive and Developmental Biology
• /
• 제35권3호
• /
• pp.233-238
• /
• 2011

This study was performed to investigate the FSH levels for superovulation procedure in Korean Native Cattle (Hanwoo). The effectiveness of 200 mg and 400 mg of FSH to initiate superovulation was examined in Hanwoo. Donors, at random stages of the estrous cycle, received a CIDR 7 days later, 200 mg FSH group was treated with 40, 30, 20, 10 mg FSH levels in declining doses twice daily by intramuscular injection fur 4 days. Also, 400 mg FSH group was treated with 80, 60, 40, 20 mg FSH levels. On the 3rd day administration of FSH, 25 mg $PGF_2$ ${\alpha}$ was administered and CIDR was withdrawn. Donors were artificially inseminated twice at 12 hr intervals. The donor cattle received 250 ${\mu}g$ GnRH at time of 1st insemination and embryos were recovered 8 days after the 1st insemination. As a results, average number of CL treated with FSH 200 mg was higher as $20.9{\pm}1.20$ than $15.8{\pm}0.63$ for donors treated with FSH 400 mg, respectively(p<0.05). Treated group of 200 mg FSH level increased (p<0.05) the number of embryos recovered per procedure compared to 400 mg FSH level ($18.2{\pm}1.18$ vs. $12.38{\pm}0.52$, respectively). When treatment of 200 mg FSH was performed, average transferable embryos/ova increased (p<0.05) to $14.1{\pm}1.12$ from $6.8{\pm}0.33$ of treated of 400 mg FSH. Group of 200 mg FSH increased (p<0.05) to $8.3{\pm}0.76$ from $2.0{\pm}0.26$ in morula stage compare to 400 mg FSH group. Mean of total early blastocyst and expanded blastocyst stage embryos was similar (p<0.05) between the 200 mg and 400 mg FSH levels group ($4.7{\pm}1.19$ vs. $2.9{\pm}0.18$ and $1.2{\pm}0.40$ vs. $1.9{\pm}0.17$). These results suggest that 200 mg FSH level-based superovulation protocol with CIDR may be effectively used fur production of superior embryos in Hanwoo. In other words, the less level of FSH may be effectively applied for Hanwoo (Korean Native Cattle), because Hanwoo was smaller body size than beef or daily cow.

• Journal of Korean Neurosurgical Society
• /
• 제51권6호
• /
• pp.363-366
• /
• 2012

Objective : Meralgia paresthetica (MP) is a syndrome of pain and/or dysesthesia in the anterolateral thigh that is caused by an entrapment of the lateral femoral cutaneous nerve (LFCN) at its pelvic exit. Despite early accounts of MP, there is still no consensus concerning the effectiveness of neurolysis or transaction treatments in the long-term relief for medically refractory patients with MP. We retrospectively analyzed available long-term results of LFCN neurolysis for medically refractory MP in an effort to clarify this issue. Methods : During the last 7 years, 11 patients who had neurolysis for MP were enrolled in this study. Nerve entrapment was confirmed preoperatively by electrophysiological studies or a positive response to local anesthetic injection. Decompression of the LFCN was performed at the level of the iliac fascia, inguinal ligament, and fascia of the thigh distally. The outcome of surgery was assessed 8 weeks after the procedure followed at regular intervals if symptoms persisted. Results : Twelve decompression procedures were performed in 11 patients over a 7-year period. The average duration of symptoms was 8.5 months (range, 4-15 months). The average follow-up period was 33 months (range, 12-60 months). Complete and partial symptom improvement were noted in nine (81.8%) and two (18.2%) cases, respectively. No recurrence was reported. Conclusion : Neurolysis of the LFCN can provide adequate pain relief with minimal complications for medically refractory MP. To achieve a good outcome in neurolysis for MP, an accurate diagnosis with careful examination and repeated blocks of the LFCN, along with electrodiagnosis seems to be essential. Possible variation in the course of the LFCN and thorough decompression along the course of the LFCN should be kept in mind in planning decompression surgery for MP.

• 해양환경안전학회지
• /
• 제17권1호
• /
• pp.1-6
• /
• 2011

인간이 환경을 보전 복원하고자 하는 목적은 자연이 인간에게 제공하는 환경서비스를 지속적으로 공급받기 위함이다. 이러한 측면에서 유류오염에 대응하고 복원하는 근본적인 목적은 인간의 생활 및 생산환경의 지속성을 유지하기 위한 것이라 할 수 있다. 즉, 유류유출의 사회경제적 피해영향 및 복원정도 모니터링은 손상된 자연환경의 기능 회복에 중요한 요소이다. 하지만 사회경제적 영향평가는 직간접적 관련자들의 이해와 직결되어 있어 적절한 조사 및 평가 방법을 선택하는 것이 어렵고 결과를 해석하는 것도 어렵다. 본 연구에서는 허베이 스피리트호 유류유출 사고를 대상으로 생활 및 생산환경 피해 모니터링의 주요 지표인 수산, 관광부문의 영향평가를 위해 기존의 문헌 및 통계자료조사 외에 지역주민 체감조사를 병행하였다. 조사 결과, 복원의 수준은 40~50 % 수준이고, 복원정도는 둔화 혹은 감소하고 있는 것으로 나타났으며, 체감조사결과가 문헌 및 통계자료 조사결과 보다 2~10 점 정도 낮은 것으로 평가되었다. 결론적으로 기존의 사회경제적 영향평가를 위해 기본적으로 수행하여 왔던 문헌 및 통계자료를 통한 분석이 피해영향 복원의 지표로 삼기에는 한계가 있음을 보여주었고, 실제 피해지역 주민들이 체감하는 영향과 복원정도에 대한 분석의 필요성을 제기하였다.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권22호
• /
• pp.9823-9829
• /
• 2014

Background: High-dose methotrexate (HD-MTX) is recognized as an efficient component of therapy against pediatric osteosarcoma in combination with other drugs such as cisplatin (CDP), carboplatin (CBDCA), doxorubicin (ADM), etoposide (VP-16) and ifosfamide (IFO). Objectives: To demonstrate the feasibility and effectiveness of the HD-MTX/CDP/DOX/VP-16/IFO [MTX(+)] protocol comparable to CDP/ADM/CBDCA/IFO [MTX(-)] for treating childhood osteosarcoma at Ramathibodi Hospital (1999-2014). Materials and Methods: A retrospective analysis was conducted of osteosarcoma patients aged less than 18 years treated with two chemotherapeutic regimens between 1999 and 2014. A total of 45 patients received the MTX(-) and 21 the MTX(+) protocol. Results: Overall limb-salvage and amputation rate were 12.9% and 77.7%, respectively. Kaplan-Meier analysis results for 3-year disease free survival (DFS) and overall survival (OS) regardless of treatment regimens were $43.4{\pm}6.0%$ and $53.2{\pm}6.1%$ respectively. The 3-year DFS and OS were improved significantly with the MTX(+) protocol compared to MTX(-) protocol (p=0.010 and p=0.009, log rank test) [$69.8{\pm}10.5%$, $79.8{\pm}9.1%$ for MTX(+) and $31.1{\pm}6.9%$, $42.2{\pm}7.4%$ for MTX(-) protocol, respectively]. Patients with metastatic osteosarcoma treated with the MTX(+) protocol had statistically significant higher 3-year DFS and OS than those treated with the MTX(-) protocol ($66.7{\pm}13.6%$ and $15.0{\pm}8.0%$ for 3-year DFS, p=0.010, $73.3{\pm}13.2%$ and $20{\pm}8.9%$ for 3-year OS, p=0.006, respectively). The independent risk factors for having inferior 3-year DFS and OS were poor histological response (tumor necrosis <90%) and treatment with the MTX(-) protocol. The multivariate analysis identified only the treatment with the MTX(-) protocol as an independent predictor of inferior OS with a hazard ratio (HR) of 3.53 (95% confidence interval of 1.2-10.41, p=0.022). Conclusions: Our study demonstrated the tolerability, feasibility and efficacy of the HDMTX-based regimen improving the survival rate in pediatric osteosarcoma cases, in line with reports from developed countries.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권6호
• /
• pp.2483-2487
• /
• 2015

This study was conducted to evaluate the effectiveness of a combination of gemcitabine and nedaplatin therapy among patients with metastatic urothelial carcinoma previously treated with two lines of chemotherapy. Between February 2009 and August 2013, 30 patients were treated with gemcitabine and paclitaxel as a second-line chemotherapy. All had received a first-line chemotherapy consisting of methotrexate, vinblastine, doxorubicin and cisplatin. Ten patients who had measurable histologically proven advanced or metastatic urothelial carcinoma of the urinary bladder and upper urinary tract received gemcitabine $1,000mg/m^2$ on days 1, 8 and 15 and nedaplatin $70mg/m^2$ on day 2 as a third-line chemotherapy. Tumors were assessed by imaging every two cycles. The median number of treatment cycles was 3.5. One patient had partial response and three had stable disease. The disease-control rate was 40%, the median overall survival was 8.8 months and the median progression-free survival was 5.0 months. The median overall survival times for the first-line and second-line therapies were 29.1 and 13.9 months, respectively. Among disease-controlled patients (n=4), median overall survival was 14.2 months. Myelosuppression was the most common toxicity. There were no therapy-related deaths. Gemcitabine and nedaplatin chemotherapy is a favorable third-line chemotherapeutic option for patients with metastatic urothelial carcinoma. Given the safety and benefit profile seen in this study, further prospective trials are warranted given the implications of our results with regard to strategic chemotherapy for patients with advanced or metastatic urothelial carcinoma.

• 산경연구논집
• /
• 제11권6호
• /
• pp.29-39
• /
• 2020

Purpose: The purpose of this study is, in the situation where rapid response to the rapidly changing environment is required due to the development of the fourth industrial revolution such as artificial intelligence, virtual reality, and the internet of things, robotics, big data, additive manufacturing, bio-health, sharing economy and in the organizational culture aspiring toward the innovation of a major company, small business and a public institution, to analyze what influence a job-engagement and stress make, and what influence individual's self-efficacy as a moderator mediator makes, and to offer basic data for improving job-engagement and lowering job-stress. Research design, data, and methodology: For doing this, the literature and the empirical studies were combined. Deriving innovation-oriented organizational culture as factors affecting the job engagement and job stress through the literature, and have established hypotheses to verify them. We have collected data of 281 from ex,ecutives and staff-members working in areas including major company, small business and officials (the central government, a local public service, the prosecution, the police, and school). And these data were analyzed by SPSS 23 version. Results: Based on these data, the results of analysis were as follows; First, the innovation-oriented organizational culture which was recognized by organizational members had effect on job-stress. Second, the innovation-oriented organizational culture which was recognized by organizational members influenced job-stress. Third, in the relationship between the innovation-oriented organizational culture and job-engagement, self-efficacy did not influenced job-engagement. Finally, in the relationship between the innovation-oriented organizational culture and job-stress, self-efficacy influenced job-stress. Conclusions: Innovation-oriented organizational culture places importance on the organization's adaptability and flexibility in the external environment, so companies need to establish an innovation-oriented organizational culture favorable to achieving survival and successful innovation, and to develop and disseminate programs of positive and continuous organizations to improve task enthusiasm, reduce task stress, and enhance organizational performance. In the future, it will be necessary to verify the effectiveness of various organizational culture types through comparative analysis with companies that actively maintain an innovation-oriented organizational culture (Google, Kakao, etc.) and companies that prefer hierarchy-oriented organizational culture, relationship-oriented organizational culture, and market-oriented organizational culture.

• 한국산학기술학회논문지
• /
• 제18권5호
• /
• pp.400-411
• /
• 2017

본 연구는 비만여성들의 모션비트 리듬운동의 실효성을 극대화하고 생활체육 현장에 적용을 기대하고자하며 그에 따른 건강증진행위의 향상과 지속적인 운동 참가의 조성방안을 제시하는데 그 목적이 있다. 리듬운동 구성은 리권운동을 기본으로 하여 모션비트를 적용한 모션비트 리듬운동 집단 18명, 모션비트를 적용하지 않은 일반비트 리듬운동 집단 18명, 통제 집단 18명으로 나누어 8주간의 중재 프로그램을 적용하였다. 비만여성들의 모션비트 리듬운동에 대한 효과는 다음과 같은 결론으로 요약할 수 있다. 뇌파 반응의 변화가 건강증진행위에 미치는 영향을 살펴보면, 모션비트 리듬운동 집단의 변화에서는 전전두엽 좌측 뇌파(알파파워)에서 스트레스관리에 대한 건강증진행위에 유의한 영향을 미쳤다. 일반비트 모션비트 집단의 변화에서는 전전두엽 양측 뇌파에서 자아실현에 대한 건강증진행위에 유의한 영향을 미쳤다. 이상의 연구결과를 종합해보면, 8주간의 모션비트를 적용한 운동을 통하여 전전두엽의 긍정적 변화가 스트레스와 관련한 건강관리행위에 재미와 흥미를 극대화시켜줌으로써 비만여성들을 위한 적절하고 효율적인 생활체육 프로그램으로 활용할 수 있을 것이다. 아울러 비만인들의 단순 신체효과를 나타낸 결과에서 벗어나 재미있고 여유로운 운동의 효과를 확보하여 지속적인 운동참가의 조성방안으로 제시될 것이라 기대해 본다.

• 한국산학기술학회논문지
• /
• 제19권4호
• /
• pp.578-585
• /
• 2018

본 논문은 고속철도차량에 전기기계제동장치(EMB : Electric Mechanical Brake)를 적용하기 위한 주요 구성품인 3상 매입형영구자석동기전동기(IPMSM : Interior Permanent Magnet Synchronous Motor)의 설계방법과 이를 이용한 인버터 제어시스템의 압부력제어 시뮬레이션 방법을 제안한다. 최근 자동차에서 주로 사용하는 유압식 제동장치는 유압을 발생시키기 위해 필요한 오일류와 유압 라인의 관리, 유지보수성 및 유압펌프의 동작으로 인한 효율성 등이 문제로 제기되면서 EMB에 대한 관심이 높아지고 있으나 비용증가 및 안전측면의 보완이 지속적으로 요구되고 있다. 공압식 제동장치를 주로 사용하는 철도차량은 EMB 시스템을 적용할 경우 차량 하부에 큰 공간을 차지하는 공기압축기, 제동공기통 및 연결 배관 등의 부품이 필요하지 않으므로 50% 이상의 소형화가 가능하며 인버터를 적용한 전동기 구동방식으로 인하여 상대적으로 빠른 응답속도와 정밀제어를 통해 공주거리를 단축시킬 수 있는 장점을 갖는다. 또한, 철도차량은 다수의 제동장치가 제동력을 분담하는 구조로 설계되어 자동차와 비교하여 EMB 적용이 안전측면에서 유리하다. 본 논문에서는 JMAG을 활용하여 고속철도의 제동 캘리퍼와 제동력 출력에 적합한 모터설계 및 전자계해석을 수행하였다. 제동 압부력 제어 시뮬레이션을 위해 기계구동부는 기존 EMB 시스템에 주로 적용된 볼스크류 형태의 동작방식과는 달리 고속철도차량에 적용된 편심축 회전을 이용한 구동방식으로 모델링하였다. IPMSM 제어를 통한 제동압부력 및 제동력 출력결과는 Matlab/Simulink를 활용하여 JMAG의 IPMSM 모델과 co-simulation을 통해 보였으며 결과의 타당성은 차세대고속철도(HEMU-430X)의 제동사양과의 비교를 통해 검증하였다.