• Physical Therapy Rehabilitation Science
• /
• v.9 no.4
• /
• pp.309-317
• /
• 2020

Objective: One of the treatment strategies for controlling chronic pain and preventing disability is patient education. Pain neuroscience education (PNE) has been proven to be effective in explaining the biological and physiological processes associated with pain experiences to patients. The purpose of this review is to investigate the effectiveness of PNE for kinesiophobia such as avoidance response in patients with chronic pain. Design: A systematic review and meta-analysis. Methods: MEDLINE, EMBASE, CINAHL, PEDro, and the Cochrane Central Register of controlled trials databases were searched through November 2020 and included a randomized controlled trials evaluating kinesiophobia in musculoskeletal patients with chronic pain. In 8 randomized controlled trial studies, 'Cochrane's risk of bias (RoB) tool was used for qualitative analysis, and results of post-intervention were analyzed through RevMan 5.4 for quantitative analysis. Results: For this review, 8 randomized controlled trials of 369 patients with chronic pain were selected for PNE. A systematic review and meta-analysis also included 8 randomized controlled trials. The effect on kinesiophobia was more effective than the control group (-0.86; 95% confidence interval [CI], -1.22 to -0.51; heterogeneity [χ²=21.18, df=7, I²=67%]; overall effect [Z=4.80]). In addition, the effect on pain was more effective than the control group (-0.53; 95% CI, -1.05 to -0.01; heterogeneity [χ²=47.42, df=7, I²=85%]; overall effect [Z=2.01]). Conclusions: The results of this review suggest that PNE and combined PNE have a positive effect on the improvement of pain and kinesiophobia in patients with chronic pain.

• Structural Engineering and Mechanics
• /
• v.81 no.5
• /
• pp.617-631
• /
• 2022

In this paper the viscoelastic responses of four experimental steel-concrete composite beams subjected to highly variable environmental conditions are investigated by means of a finite element (FE) model. Concrete specimens submitted to stepped stress changes are also evaluated to validate the current formulations. Here, two well-known approaches commonly used to solve the viscoelastic constitutive relationship for concrete are employed. The first approach directly solves the integral-type form of the constitutive equation at the macroscopic level, in which aging is included by updating material properties. The second approach is postulated from a rate-type law based on an age-independent Generalized Kelvin rheological model together with Solidification Theory, using a micromechanical based approach. Thus, conceptually both approaches include concrete hardening in two different manners. The aim of this work is to compare and analyze the numerical prediction in terms of long-term deflections of the studied specimens according to both approaches. To accomplish this goal, the performance of several well-known model codes for concrete creep and shrinkage such as ACI 209, CEB-MC90, CEB-MC99, B3, GL 2000 and FIB-2010 are evaluated by means of statistical bias indicators. It is shown that both approaches with minor differences acceptably match the long-term experimental deflection and are able to capture complex oscillatory responses due to variable temperature and relative humidity. Nevertheless, the use of an age-independent scheme as proposed by Solidification Theory may be computationally more advantageous.

• Journal of the Korea Institute of Information Security & Cryptology
• /
• v.32 no.2
• /
• pp.267-277
• /
• 2022

Due to the increasing proportion of cloud and remote working environments, various information security incidents are occurring. Insider threats have emerged as a major issue, with cases in which corporate insiders attempting to leak confidential data by accessing it remotely. In response, insider threat detection approaches based on machine learning have been developed. However, existing machine learning methods used to detect insider threats do not take biases and variances into account, which leads to limited performance. In this paper, boosting-type ensemble learning algorithms are applied to verify the performance of malicious insider detection, conduct a close analysis, and even consider the imbalance in datasets to determine the final result. Through experiments, we show that using ensemble learning achieves similar or higher accuracy to other existing malicious insider detection approaches while considering bias-variance tradeoff. The experimental results show that ensemble learning using bagging and boosting methods reached an accuracy of over 98%, which improves malicious insider detection performance by 5.62% compared to the average accuracy of single learning models used.

• Nutrition Research and Practice
• /
• v.16 no.sup1
• /
• pp.70-88
• /
• 2022

Sodium is a physiologically essential nutrient, but excessive intake is linked to the increased risk of various chronic diseases, particularly cardiovascular. It is, therefore, necessary to accomplish an evidence-based approach and establish the Korean Dietary Reference Intakes (KDRIs) index, to identify both the nutritional adequacy and health effects of sodium. This review presents the rationale for and the process of revising the KDRIs for sodium and, more importantly, establishing the sodium Chronic Disease Risk Reduction Intake (CDRR) level, which is a new specific set of values for chronic disease risk reduction. To establish the 2020 KDRIs for dietary sodium, the committee conducted a systematic literature review of the intake-response relationships between the selected indicators for sodium levels and human chronic diseases. In this review, 43 studies published from January 2014 to December 2018, using databases of PubMed and Web of Science, were finally included for evaluating the risk of bias and strength of evidence (SoE). We determined that SoE of the relationship between dietary sodium and cardiovascular diseases, cerebrovascular disease, and hypertension, was moderate to strong. However, due to insufficient scientific evidence, we were unable to establish the estimated average requirement and the recommended nutrient intake for dietary sodium. Therefore, the adequate intake of sodium for adults was established to be 1,500 mg/day, whereas the CDRR for dietary sodium was established at 2,300 mg/day for adults. Intake goal for dietary sodium established in the 2015 KDRIs instead of the tolerable upper intake level was not presented in the 2020 KDRIs. For the next revision of the KDRIs, there is a requirement to pursue further studies on nutritional adequacy and toxicity of dietary sodium, and their associations with chronic disease endpoint in the Korean population.

• The Journal of Korean Medicine
• /
• v.44 no.2
• /
• pp.201-201
• /
• 2023

Objectives: Cupping therapy (CT) has been widely used in traditional medicine worldwide for various indications, including stroke. The aim of this study was to systematically review the clinical evidence of CT for stroke. Methods: To identify randomized controlled trials (RCTs) reporting the effectiveness and/or safety of CT, seven databases including PubMed, EMBASE, and Cochrane Library were searched for articles published from January 2000 to February 2021 without language restrictions. Meta-analysis was performed using Review Manager 5.4 software and the results were presented as mean difference (MD) or standard mean difference (SMD) for continuous variables and odds ratio (OR) for diverse variables with 95% confidence intervals (CIs). Assessment of the methodological quality of the eligible trials was conducted using the Cochrane Collaboration tool for risk of bias in RCTs. Results: Twenty-two RCTs with 1653 participants were included in the final analysis. CT provided additional benefit in improving upper limb motor function (Fugl-Meyer assessment for upper limb motor function, MD 6.91, 95% CI 4.64 to 1.67, P<0.00001) and spasticity (response rate, OR 3.28, 95% CI 1.31 to 8.22, P=0.08) in stroke survivors receiving conventional medical treatment. These findings were supported with a moderate level of evidence. CT did not significantly increase the occurrence of adverse events. Conclusions: This study demonstrated the potential of CT to be beneficial in managing a variety of complications in stroke survivors. However, to compensate for the shortcomings of the existing evidence, rigorously designed large-scale RCTs are warranted in the future.

• Nuclear Engineering and Technology
• /
• v.55 no.12
• /
• pp.4576-4582
• /
• 2023

The Korea retrospective dosimetry (KREDOS)-electron paramagnetic resonance (EPR) group undertook an intercomparison investigation utilizing hydroxyapatite. This analysis involved four institutions: the Korea Institute of Radiological and Medical Sciences, Dongnam Institute of Radiological and Medical Sciences, Korean Association for Radiation Application, and Radiation Health Institute of Korea Hydro & Nuclear Power. Following the irradiation of the hydroxyapatite sample, the recorded build-up was analyzed. To validate the reliability of the EPR dosimetry findings and enhance its operational performance, a hydroxyapatite dose-response curve was plotted and dosimetry was performed for a blind sample. The proficiency of each laboratory was assessed by employing an interlaboratory comparison methodology. This involved a comparative analysis of the measurement results by calculating the relative bias, z-score, and En value. The results submitted by the participating laboratories demonstrated satisfactory ratings for doses of 1.006, 3.999, and 6.993 Gy. Following the second intercomparison, efforts to optimize their hydroxyapatite-EPR dosimetry systems are underway in the participating laboratories. The current assessment of hydroxyapatite dose yielded the foundational data required to establish the parameters of dental dosimetry. In future, the third intercomparison experiment will be conducted for exploring other materials.

• Proceedings of the KSR Conference
• /
• 2011.10a
• /
• pp.1730-1738
• /
• 2011

Personal Rapid Transit (PRT) has emerged as a promising alternative transportation mode for transit-oriented sustainable communities by creating compact and walkable environments with competitive construction and operational costs. This study seeks to capture the changes in travel mode choice behavior in response to the introduction of PRT to travelers who have no previous experience of using it. A critical issue in modeling the PRT mode choice is how to capture travelers' perception and evaluation of the unexperienced travel mode. The data used come from questionnaire surveys, in which RP (Revealed Preference) and SP (Stated Preference) data were collected in relation to travel mode choices with and without PRT systems. The questionnaire was designed especially for mitigating the potential bias in favor of or against choosing PRT. In addition, an efficient approach was proposed to reduce the number of SP questions by avoiding the complex fractional factorial design which tends to make it difficult for respondents to keep their attention throughout the survey. The analysis results show that the proposed approach is able to realistically capture the effects of explanatory variables on the travel mode choice. Discrete choice models are developed to predict travelers' mode choices under different choice scenarios by varying PRT system specifications and operational characteristics. PRT patronages are projected for two different test sites using the developed PRT mode choice models.

• Journal of Microbiology and Biotechnology
• /
• v.15 no.6
• /
• pp.1323-1329
• /
• 2005

A mathematical model was developed for predicting the growth kinetics of Listeria monocytogenes in tryptic soy broth (TSB) as a function of combined effects of temperature, pH, and NaCl. The TSB containing four different concentrations of NaCl (2, 4, 5, and $10\%$) was initially adjusted to six different pH levels (pH 5, 6, 7, 8, 9, and 10) and incubated at 4, 10, 25, or 37$^{circ}C$. In all experimental variables, the primary growth curves were well fitted ($r^{2}$=0.982 to 0.998) to a Gompertz equation to obtain the lag time (LT) and specific growth rate (SGR). Surface response models were identified as appropriate secondary models for LT and SGR on the basis of coefficient determination ($r^{2}$=0.907 for LT, 0.964 for SGR), mean square error (MSE=3.389 for LT, 0.018 for SGR), bias factor ($B_{1}$B,=0.706 for LT, 0.836 for SGR), and accuracy factor ($A_{f}$=1.567 for LT, 1.213 for SGR). Therefore, the developed secondary model proved reliable predictions of the combined effect of temperature, NaCl, and pH on both LT and SGR for L. monocytogenes in TSB.

• Journal of Gifted/Talented Education
• /
• v.25 no.4
• /
• pp.469-491
• /
• 2015

The present study investigated the inhibition mechanisms of gifted children, which is one of the main executive functions in human cognitive system. The inhibition process was subdivided into cognitive and emotion aspects in order to examine the interplay between these two aspects with respect to inhibition processing. In Experiment 1, word-color Stroop task was used to study the cognitive inhibition process of 100 gifted children(Gender: 62 males, 38 females; Academic grade: 46 Elementary school students, 54 Secondary school students). In addition, emotional Stroop task was utilized in Experiment 2 to examine the effect of emotional component during cognitive inhibition process. Results revealed a significant cognitive cost (i.e., word-color Stroop effect) when participants had to withhold automatic response during cognitive inhibition task in Experiment 1. Such cognitive cost was reduced as the chronological age of the participants increased, with no difference in gender. The results in Experiment 2 showed no significant emotional inhibition cost (i.e., emotional Stroop effect) during cognitive inhibition task, and there was no effect of gender nor age. This suggests that the emotional component conveyed in words did not lead to cognitive bias effects. This study proposes that the cognitive and emotional inhibition processes are seemingly independent mechanisms that engage in complex interactions during inhibition processing of behavioral response.

• Health Policy and Management
• /
• v.10 no.4
• /
• pp.57-74
• /
• 2000

This study is conducted to compare how the Western.Oriental medical practitioners and health professionals perceive reciprocal development strategies respectively of Western.Oriental Medicine in Korea. A total of 3,273 persons were questioned by direct distribution, e-mail, and mail with a self-developed questionnaire. Of those questioned, 362 responded (the response rate of 11.1%), and of them n persons (Western medical practitioners 206, Oriental medical practitioners 90, and health professionals 64) were analyzed with SPSS for Windows. The results were as follows： The need for legislation on the mutual development system for Western.Oriental Medicine was recognized by 66.9% (218 persons) of respondents. Among them, largest group who agreed with this need was the health professionals. Western medical practitioners chose the "the difference of approach methods on the diseases between Western.Oriental Medicine" as their response, and Oriental medical practitioners ＆ health professionals selected "the indifference or bias of Western medical practitioners"as the reasons for the inactivity in developing a mutual system of Western.Oriental Medicine. Therefore, Western medical practitioners and health professionals selected the category of "the reformation of educational system", while Oriental medical practitioners selected the category of "the activation of joint research on Western.Oriental medical care" as the most important condition for setting a precedent. Also, Western medical practitioners preferred "cooperative health care system for Western medical care supported by Oriental medical care", but Oriental medical practitioners and health professionals preferred “cooperative health care system of Western.Oriental medicine on equal terms" In conclusion, Western '||'&'||' Oriental medical practitioners have to make every effort to close the gap between differing views through mutual understanding and respect if joint research of Western.Oriental medical care is to become a reality. The government should continuously enforce the health policy on development of a legal and systematic infrastructure for mutual development strategy of Western.Oriental Medicine in Korea.strategy of Western.Oriental Medicine in Korea.