• Title/Summary/Keyword: response assessments

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Uncertainties in Risk Assessment

  • Hattis Dale;Froines John
    • 대한예방의학회:학술대회논문집
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    • 1994.02a
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    • pp.440-449
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    • 1994
  • Current risk assessment practices largely reflect the need for a consistent set of relatively rapid, first-cut procedures to assess 'plausible upper limits' of various risks. These practices have important roles to play in 1) screening candidate hazards for initial attention and 2) directing attention to cases where moderate-cost measures to control exposures are likely to be warranted, in the absence of further extensive (and expensive) data gathering and analysis. A problem with the current practices, however, is that they have led assessors to do a generally poor job of analyzing and expressing uncertainties, fostering 'One-Number Disease' (in which everything from one's social policy position on risk acceptance to one's technical judgment on the likelihood of different cancer dose-response relationships is rolled into a single quantity). At least for analyses that involve relatively important decisions for society (both relatively large potential health risks and relatively large potential economic costs or other disruptions), we can and should at least go one further step - and that is to assess and convey both a central tendency estimate of exposure and risk as well as our more conventional 'conservative' upper-confidence-limit values. To accomplish this, more sophisticated efforts are needed to appropriately represent the likely effects of various sources of uncertainty along the casual chain from the release of toxicants to the production of adverse effects. When the effects of individual sources of uncertainty are assessed (and any important interactions included), Monte Carlo simulation procedures can be used to produce an overall analysis of uncertainties and to highlight areas where uncertainties might be appreciably reduced by further study. Beyond the information yielded by such analyses for decision-making in a few important cases, the value of doing several exemplary risk assessments in. this way is that a set of benchmarks can be defined that will help calibrate the assumptions used in the larger number of risk assessments that must be done by 'default' procedures.

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Effect of Nutritional Status on Cell-mediated and Humoral Immunity in Female College Students (인체의 영양상태가 세포매개성 및 체액성 면역 반응에 미치는 영향)

  • 김현미
    • Journal of Nutrition and Health
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    • v.27 no.5
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    • pp.483-494
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    • 1994
  • The purpose of this study was to investigate the effect of nutritional status on the cell-mediated and humoral immunity in female college students. The nutritional status of twenty subjects was determined by six-days food records, anthropometric measurements, and biochemical assessments of serum nutrients. Cell-mediated and humoral immunity of the subjects was analyzed by in vivo and in vitro assessments. The results were summerized as follows : First, The average daily energy intake was 1437Kcal(CHO : PRO : FAT = 61:13:26), which corresponds to 71.9% of RDA. Anthropometric measurements showed that 50% of the subjects was under-weight(BMI<20), only 5% was over-weight(25

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New ecological health assessment approaches of an urban stream using molecular and physiological level biomarkers and bioindicators

  • Kim, Ja-Hyun;Yeom, Dong-Hyuk;Kim, Joon-Ha;An, Kwang-Guk
    • Animal cells and systems
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    • v.16 no.4
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    • pp.329-336
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    • 2012
  • This study evaluated ecological health, using various biomarkers and bioindicators, of pale chub (Zacco platypus) as a sentinel species, in Daejeon Stream, South Korea, during AprilMay 2011. The biomarkers and bioindicators were compared among three sites of control: Reference ($C_z$), transition ($T_z$), and the urban zones ($U_z$); and the 7-Ethoxyresorufin-O-deethylase (EROD) activity, DNA damage, acetylcholinesterase (AChE) activity, and vitellogenin (VTG) concentrations were more significantly increased in the $U_z$ than in the $C_z$. Also, physiological markers such as condition factor, liver somatic index, visceral somatic index, and gonad somatic index were significantly increased in the $U_z$ than in the $C_z$. For the health assessments, three categorized parameters of blood chemistry, molecular biomarkers, and physiological bioindicators were standardized and calculated as a star-plot, representing values of Integrated Health Response (IHR). Values of IHR had more significant (P<0.05) increases in the $U_z$ than any other zones, indicating an impairment of ecological health by organic matter, nutrients (N, P), and toxic chemicals. This study is based on low levels of biological organization approach of molecular and physiological biomarkers and bioindicators, so further study of high-levels of biological organization approach such as community and population is required for overall range of health assessments. The approach of IHR values, however, may be useful in providing early warning of future impacts on ecological health.

Study on the Subjective Responses of Loudness and Annoyance according to Exposed Time for the Traffic Noise (도심교통소음의 노출시간에 따른 라우드니스 및 어노이언스의 주관적 반응에 대한 연구)

  • Hur, Deog-Jae;Jo, Kyoung-Sook;Choe, Byong-Ho
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.17 no.3 s.120
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    • pp.241-248
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    • 2007
  • A study has been conducted to investigate the subjective responses of loudness and annoyance according to the exposed time of urban traffic noise in controlled laboratory environment. To make a closer inspection into psychological response relevant to noise characteristics while varying the time of exposure to noise, the subjects were presented a set of noises with different exposed time and requested to judge spontaneously on a 100-unipolar scale. To be concrete, the subjects were exposed to noises being varied in time from 15 sec up to max. 1,200 sec for the controlled traffic noise sources. So far achieved from laborious tests, it has an importance being on the logarithmic relations of perceived loudness and exposed time, say, it is more increased the perceived loudness in the sorter exposed time than in the longer exposed time. However, the trend is said to be not effective for the case of annoyance. On the other hand, the subjective impressions on relative annoyance of noise is shown to be correlated with the noise characteristics such as loudness (sones), tonality and time with logarithmic scale, the product correlation moment being calculated as $R^{2}=0.99$. The variances to be explained for annoyance assessments through varying the time of exposure were ranged between 30 % and 50% for the exposed time, $27{\sim}37%$ for tonality, and $34{\sim}20%$ for loudness, respectively With these results, hopefully, it can be helpful for those who want to work out an experimental design for evaluating an environmental noise or to quantify any psychological dimensions found in annoyance assessments.

A New Multivariate System Process Capability Index (다변량 시스템 공정능력지수(SCpsk))

  • 조남호;이용훈
    • Journal of the Korea Safety Management & Science
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    • v.5 no.3
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    • pp.145-156
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    • 2003
  • As we understand it, Process Capability indices are intended to provide single-number assessments of ability to meet specification limits on quality characteristics of interest. As a consequence of the varied ways in which PCIs are used, there have been two natural lines of research work: $\circled1$ studies on the properties of PCIs and their estimators in many different environments; $\circled2$ construction of new PCIs purporting to have better properties in certain circumstances. The most of existing process capability indices are concerned with the single variable. But, in many cases, a quality characteristic is composed with several factors. In that case, we want to know the integrated process capability of a quality characteristic not those of each factor. In this paper, we proposed a new multivariate system process capability index called $MSPCI:SC_{psk}$ which is the geometric mean of performance measure $C_{psk}$'S, and will be used as the criterion to assess multiple response process designs. Numerical illustration is done for $SC_{psk}$, $\overline{C_p}$(f), Cp, Cpk, Cpm, and Cpsk.

Performance of R/C Bridge Piers under Seismic Loads

  • Kang, Hong-Duk;Kang, Young-Jong;Yoon, Young-Soo
    • KCI Concrete Journal
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    • v.12 no.1
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    • pp.35-46
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    • 2000
  • A research program was initiated at the University of Colorado at Boulder to develop computational models that can be used for seismic risk assessments. To assess the overall performance of bridge structures including the nonlinear effects of bridge piers, the research focused on two levels of capabilities, i.e. global and local pier levels. A 3-D concrete model was used to evaluate the behavior of individual piers under combined axial, bending, and shear loadings using 3-D finite element analysis. Whereby the response curve reached the peak strength of the R/C column under the constant axial and monotonically increasing lateral loads. Experimental results on reinforced concrete bridge piers, which were obtained at the University of California at San Diego were used to validate the seismic performance of bridge piers at the two levels, globa1 and local.

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REACTIVITY OSCILLATION IN SOURCE-DRIVEN SYSTEMS

  • Dulla, S.;Nicolino, C.;Ravetto, P.
    • Nuclear Engineering and Technology
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    • v.38 no.7
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    • pp.657-664
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    • 2006
  • The problem of reactivity oscillations for a point reactor constitutes an interesting aspect of nuclear reactor physics and its solution may give important information for dynamic and safety assessments. The present paper considers the problem of a reactivity oscillation for a source-driven system which involves some specific aspects that introduce significant differences with respect to the source-free situation. Assuming a square-wave shape for the reactivity insertion, the solution is derived by a fully analytical approach. The conditions for stability and instability can be identified in a straightforward way by directly studying the stationarity of the power response. Numerical results presented allow to discuss the role of the system kinetic parameters and of the time-shape of the reactivity wave.

Evaluation of local and global ductility relationships for seismic assessment of regular masonry-infilled reinforced concrete frames using a coefficient-based method

  • Su, R.K.L.;Tang, T.O.;Lee, C.L.
    • Earthquakes and Structures
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    • v.5 no.1
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    • pp.1-22
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    • 2013
  • Soft storey failure mechanism is a common collapse mode for masonry-infilled (MI) reinforced concrete (RC) buildings subjected to severe earthquakes. Simple analytical equations correlating global with local ductility demands are derived from pushover (PO) analyses for seismic assessments of regular MI RC frames, considering the critical interstorey drift ratio, number of storeys and lateral loading configurations. The reliability of the equations is investigated using incremental dynamic analyses for MI RC frames of up to 7 storeys. Using the analytical ductility relationship and a coefficient-based method (CBM), the response spectral accelerations and period shift factors of low-rise MI RC frames are computed. The results are verified through published shake table test results. In general applications, the analytical ductility relationships thus derived can be used to bypass the onerous PO analysis while accurately predicting the local ductility demands for seismic assessment of regular MI RC frames.

Evaluation of Regional Drought Vulnerability Assessment Based on Agricultural Water and Reservoirs (지역기반 농업용수의 가뭄재해 취약성 평가)

  • Mun, Young-Sik;Nam, Won-Ho;Jeon, Min-Gi;Kim, Han-Joong;Kang, Ku;Lee, Jung-Chul;Ha, Tae-Hyun;Lee, Kwangya
    • Journal of The Korean Society of Agricultural Engineers
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    • v.62 no.2
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    • pp.97-109
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    • 2020
  • Drought is one of the most influential disasters in sustainable agriculture and food security of nations. In order to preemptively respond to agricultural droughts, vulnerability assessments were conducted to predict the possibility of drought in the region, the degree of direct or indirect damage, and the ability to cope with the damage. Information on agricultural drought vulnerability status of different regions is extremely useful for implementation of long term drought management measures. The purpose of this study is to develop and implement a quantitative approach for measuring agricultural drought vulnerability at sub-district level based on agricultural water and reservoirs. To assess the vulnerability in a quantitative manner and also to deal with different physical and socioeconomic data on the occurrence of agricultural drought, we selected the appropriate factors for the assessment of agricultural drought vulnerability through preceding studies, and analyzed the meteorological and agricultural reservoir data from 2015 to 2018. Each item was weighted using AHP (Analytic Hierarchy Process) analysis and evaluated through the agricultural drought vulnerability estimation. The entire national vulnerability assessments showed that Ganghwa, Naju, and Damyang were the most vulnerable to agricultural droughts. As a result of analyzing spatial expression, Gyeongsang-do is relatively more vulnerable to drought than Gangwon-do and Gyeonggi-do. The results revealed that the methodology and evaluation items achieved good performance in drought response. In addition, vulnerability assessments based on agricultural reservoir are expected to contribute supporting effective drought decisions in the field of agricultural water management.

Characterization of Reinforcing Efficiency in Hybrid Fiber Reinforced Cementitous pastes (하이브리드 섬유보강 시멘트 페이스트의 보강효율에 대한 특성화)

  • Park, Tae-Hyo;Noh, Myung-Hyun;Park, Choon-Keun
    • Proceedings of the Korea Concrete Institute Conference
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    • 2004.05a
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    • pp.644-647
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    • 2004
  • Modulus of rupture (MOR) and flexural toughness in hybrid fiber reinforced cement pastes mixed with micro-fiber (carbon fiber) and macro-fiber (steel fiber) and replaced with silica fume according to the fixed ratio were researched. Reinforcing efficiency in specimens were estimated by two factors, such as strengthening factor $(F_s)$ and toughening factor $(F_t)$, which were calculated from the analysis of variance (ANOVA) of the response values, such as MOR and absorbtion energy $(W_0)$. According to the experimental design by the fractional orthogonal array, nine hybrid fibrous reinforced paste series and one non-reinforced control paste were manufactured. Specimens of each series were tested by the INSTRON Inc. 8502(model) equipment in three-points bending and then measured the load-deflection response relationships. Considerable strengthening of cement pastes resulted in' the case of other factors without carbon fiber and toughening of cement pastes about all factors showed high. Based on the significance of factors related to response values from ANOVA, following assessments were available; $F_s$ or MOR: silica fume $\gg$ steel fiber $\gg$ carbon fiber; $F_t\;or\;W_0$: steel fiber > carbon fiber > silica fume. Optimized composition condition was estimated by steel fiber of $1.5\%$, carbon fiber of $0.5\%$ and silica fume $7.5\%$ in side of strengthening and steel fiber of $1.5\%$, carbon fiber of $0.75\%$ and silica fume $7.5\%$ in side of toughening.

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