• Title/Summary/Keyword: resistance management

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Ginseng Cultural Management and Research Update in Atlantic Canada

  • Ju, H.Y.;Asiedu, S.K.;Hong, S.C.;Gray, B.;Sampson, G.;LeBlanc, P.
    • Proceedings of the Ginseng society Conference
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    • 1998.06a
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    • pp.103-108
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    • 1998
  • The Canadian production of American ginseng (Panax quinquefolius L.) occurs mainly in Ontario, British Columbia and the Atlantic provinces. Although ginseng is a profitable crop, its successful production is dependent on careful consideration of cultural management f include site selection, site preparation, seed selection and handling, shading actors which and mulching, pest and nutritional management, and handling of harvested crops. Diseases of particular concern in Atlantic Canada are root rots caused by Phytopkthora cactorum, Cylindrocarpon destructans and Fusarium sp. Recently two systemic fungicides (metalaxyl and fosetylal) were registered; however, growers in Atlantic Canada have experienced metalaxyl resistance resulting from the reliance on this single compound for the control of Phytophthora sap. Current research being conducted on alternative control of these diseases will be discussed. In weed control research, 2, 4-D, MCPA, clopyralid have continued to show promise for weed contro1 at low rates. In trials to evaluate non-selective herbicides as post-senescence or pre-emergence in ginseng, glyphosate (Round-up) provided control of perennials as well as willowherb and lambsquarters. In phytoxicity trials, ginseng significantly tolerated grass herbicides, including clethodim, rimsulfuron, trakloxydim, nicosulfuron and fenoxyprop. For broadleaf herbicides, significant tolerance was shown for bromoxynil, thifensulfuron methyl, flumetulam/clopyralid, thifensulfuro/tribenuron. Disease and weed management of ginseng in Atlantic Canada will be discussed.

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Finite Element Analysis of Carbon Fiber Composite Sandwich Panels Subjected to Wind Debris Impacts

  • Zhang, Bi;Shanker, Ajay
    • International conference on construction engineering and project management
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    • 2022.06a
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    • pp.436-442
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    • 2022
  • Hurricanes and tornadoes are the most destructive natural disasters in some central and southern states. Thus, storm shelters, which can provide emergency protections for low-rise building residents, are becoming popular nowadays. Both FEMA and ICC have published a series of manuals on storm shelter design. However, the authors found that the materials for related products in the market are heavyweight and hard to deliver and install; renovations are necessary. The authors' previous studies found that lightweight and high-performance composite materials can withstand extreme wind pressure, but some building codes are designated in wind-borne debris areas. In these areas, wind debris can reach greater than 100 mph speed. In addition, the impact damage on the composite materials is an increasing safety issue in many engineering fields; some can cause catastrophic results. Therefore, studying composite structures subjected to wind debris impact is essential. The finite element models are set up using the software Abaqus 2.0 to conduct the simulations to observe the impact resistance behavior of the carbon fiber composite sandwich panels. The selected wood debris models meet the FEMA requirements. The outcome of this study is then employed in future lab tests and compared with other material models.

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Therapeutic applications of ginseng for skeletal muscle-related disorder management

  • Syed Sayeed Ahmad;Hee Jin Chun;Khurshid Ahmad;Inho Choi
    • Journal of Ginseng Research
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    • v.48 no.1
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    • pp.12-19
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    • 2024
  • Skeletal muscle (SM) is the largest organ of the body and is largely responsible for the metabolism required to maintain body functions. Furthermore, the maintenance of SM is dependent on the activation of muscle satellite (stem) cells (MSCs) and the subsequent proliferation and fusion of differentiating myoblasts into mature myofibers (myogenesis). Natural compounds are being used as therapeutic options to promote SM regeneration during aging, muscle atrophy, sarcopenia, cachexia, or obesity. In particular, ginseng-derived compounds have been utilized in these contexts, though ginsenoside Rg1 is mostly used for SM mass management. These compounds primarily function by activating the Akt/mTOR signaling pathway, upregulating myogenin and MyoD to induce muscle hypertrophy, downregulating atrophic factors (atrogin1, muscle ring-finger protein-1, myostatin, and mitochondrial reactive oxygen species production), and suppressing the expressions of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in cachexia. Ginsenoside compounds are also used for obesity management, and their anti-obesity effects are attributed to peroxisome proliferator activated receptor gamma (PPARγ) inhibition, AMPK activation, glucose transporter type 4 (GLUT4) translocation, and increased phosphorylations of insulin resistance (IR), insulin receptor substrate-1 (IRS-1), and Akt. This review was undertaken to provide an overview of the use of ginseng-related compounds for the management of SM-related disorders.

Streamlining ERP Deployment in Nepal's Oil and Gas Industry: A Case Analysis

  • Dipa Adhikari;Bhanu Shrestha;Surendra Shrestha;Rajan Nepal
    • International Journal of Advanced Culture Technology
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    • v.12 no.3
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    • pp.140-147
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    • 2024
  • Oil and gas industry is a unique sector with complex activities, long supply chains and strict rules for the business. It is important to use enterprise resource planning (ERP) systems to address these challenges as it helps in simplifying operations, improving efficiency and facilitating evidence-based decision making. Nonetheless, successful integration of ERP systems in this industry involves careful planning, customization and alignment with specific business processes including regulatory requirements. Several critical factors, such as strong change management, support of top managers and training that works have been identified in the study. Amongst the hurdles are employee resistance towards the changes, data migration complications and integration with existing systems. Nonetheless, NOCL's ERP implementation resulted in significant improvements in operating efficiency, better data visibility and compliance management. It also led to a decrease in financial reporting timeframes, more accurate inventory tracking and improved decision-making capabilities. The study provides useful insights on how to optimize oil and gas sector ERP implementations; key among them is practical advice including strengthening change management strategies, prioritizing data security and collaborating with ERP vendors. The research highlights the importance of tailoring ERP solutions to specific industry needs as well as emphasizes the strategic role of ongoing monitoring/feedback for future benefits sustainability.

Effect of Change Management Capability in Real-Time Environment: An Information Orientation Perspective in Supply Chain Management (실시간 환경에서 변화관리의 영향에 관한 연구: 공급사슬망상의 정보역량관점에서)

  • Park, Kwang-O
    • Management & Information Systems Review
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    • v.36 no.2
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    • pp.1-20
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    • 2017
  • SCM system is a strategic cooperative that organically integrates all supply chains to improve the performance of a company. For effective SCM system, emphasis is placed on securing long-term, mutual relationships and change management. The implementation of an SCM system is likely to introduce a wide range of changes in and across member organizations and these changes are likely to be met with scepticism and resistance by individuals and organizations in the chain. Thus, the success of an SCM system cannot be guaranteed without effective change management. And we adopted the concept of information orientation (IO) as our method to measure the performance of an SCM system through information quality and information sharing. Therefore, this study examined the influence of mutual, reciprocal relationships among change management on information capability through information quality and information Sharing. The results of this study can be summarized as follows. First, change management had a significant influence on information quality, information Sharing and information capability. Second, information quality had a significant influence on information Sharing and information capability. Third, information sharing had a significant influence on information capability.

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Attitude Confidence and User Resistance for Purchasing Wearable Devices on Virtual Reality: Based on Virtual Reality Headgears (가상현실 웨어러블 기기의 구매 촉진을 위한 태도 자신감과 사용자 저항 태도: 가상현실 헤드기어를 중심으로)

  • Sohn, Bong-Jin;Park, Da-Sul;Choi, Jaewon
    • Journal of Intelligence and Information Systems
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    • v.22 no.3
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    • pp.165-183
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    • 2016
  • Over the past decade, there has been a rapid diffusion of technological devices and a rising number of various devices, resulting in an escalation of virtual reality technology. Technological market has rapidly been changed from smartphone to wearable devices based on virtual reality. Virtual reality can make users feel real situation through sensing interaction, voice, motion capture and so on. Facebook.com, Google, Samsung, LG, Sony and so on have investigated developing platform of virtual reality. the pricing of virtual reality devices also had decreased into 30% from their launched period. Thus market infrastructure in virtual reality have rapidly been developed to crease marketplace. However, most consumers recognize that virtual reality is not ease to purchase or use. That could not lead consumers to positive attitude for devices and purchase the related devices in the early market. Through previous studies related to virtual reality, there are few studies focusing on why the devices for virtual reality stayed in early stage in adoption & diffusion context in the market. Almost previous studies considered the reasons of hard adoption for innovative products in the viewpoints of Typology of Innovation Resistance, MIR(Management of Innovation Resistant), UTAUT & UTAUT2. However, product-based antecedents also important to increase user intention to purchase and use products in the technological market. In this study, we focus on user acceptance and resistance for increasing purchase and usage promotions of wearable devices related to virtual reality based on headgear products like Galaxy Gear. Especially, we added a variables like attitude confidence as a dimension for user resistance. The research questions of this study are follows. First, how attitude confidence and innovativeness resistance affect user intention to use? Second, What factors related to content and brand contexts can affect user intention to use? This research collected data from the participants who have experiences using virtual rality headgears aged between 20s to 50s located in South Korea. In order to collect data, this study used a pilot test and through making face-to-face interviews on three specialists, face validity and content validity were evaluated for the questionnaire validity. Cleansing the data, we dropped some outliers and data of irrelevant papers. Totally, 156 responses were used for testing the suggested hypotheses. Through collecting data, demographics and the relationships among variables were analyzed through conducting structural equation modeling by PLS. The data showed that the sex of respondents who have experience using social commerce sites (male=86(55.1%), female=70(44.9%). The ages of respondents are mostly from 20s (74.4%) to 30s (16.7%). 126 respondents (80.8%) have used virtual reality devices. The results of our model estimation are as follows. With the exception of Hypothesis 1 and 7, which deals with the two relationships between brand awareness to attitude confidence, and quality of content to perceived enjoyment, all of our hypotheses were supported. In compliance with our hypotheses, perceived ease of use (H2) and use innovativeness (H3) were supported with its positively influence for the attitude confidence. This finding indicates that the more ease of use and innovativeness for devices increased, the more users' attitude confidence increased. Perceived price (H4), enjoyment (H5), Quantity of contents (H6) significantly increase user resistance. However, perceived price positively affect user innovativeness resistance meanwhile perceived enjoyment and quantity of contents negatively affect user innovativeness resistance. In addition, aesthetic exterior (H6) was also positively associated with perceived price (p<0.01). Also projection quality (H8) can increase perceived enjoyment (p<0.05). Finally, attitude confidence (H10) increased user intention to use virtual reality devices. however user resistance (H11) negatively affect user intention to use virtual reality devices. The findings of this study show that attitude confidence and user innovativeness resistance differently influence customer intention for using virtual reality devices. There are two distinct characteristic of attitude confidence: perceived ease of use and user innovativeness. This study identified the antecedents of different roles of perceived price (aesthetic exterior) and perceived enjoyment (quality of contents & projection quality). The findings indicated that brand awareness and quality of contents for virtual reality is not formed within virtual reality market yet. Therefore, firms should developed brand awareness for their product in the virtual market to increase market share.

Clinical Features and Management of Multidrug-Resistant Tuberculosis (다제 내성 폐결핵 환자의 임상상 및 치료에 대한 고찰)

  • Lee, Jae-Cheol;Lee, Seung-Jun;Kim, Gye-Soo;Yoo, Chul-Gyu;Cheong, Hee-Soon;Kim, Young-Whan;Han, Sung-Koo;Shim, Young-Soo
    • Tuberculosis and Respiratory Diseases
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    • v.43 no.1
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    • pp.14-21
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    • 1996
  • Objectives: Although outbreak of MDR Tb has been a recent problem in western countries, it has been a longstanding problem in Korea. The poor outcome of MDR Tb is mainly due to poor compliance, high rate of side reaction of secondary drugs, and limitation in number of available drugs. Thus, to improve the outcome of MDR Tb, it is crucial to make individualized adequate prescription based on the knowledge of the patterns of resistance to each drugs in the community as well as the natural history. The purpose of present study is to evaluate the clinical features of Korean MDR Tb patients including patterns of drug resistance and success rate of treatment which was prescribed according to the sensitivity tests. Methods: Retroscpective analysis of 71 Korean patients with MDR Tb was made. All strains isolated from patients showed resistence to at least two first line drugs. Patients profile, previous treatment history, patterns of drug resistance, outcome of treatment was analysed. Initial treatment regimen was selected according to the previous treatment history and was modified according to the sensitivity reports. The regimen was composed to include at least 4 sensitive drugs when possible. Results: The patients showed resistance to 4.1 drugs on average. 90% of them were resistant to INH and RFP. Among 71 patients, 35 patients(49%) had cavitary lesions in CXR. Treatment outcome was analysed in 55 patients. 35 patients(67%) were improved after treatment and 18 patients(33%) showed treatment failure. 5 patients showed primary resistance. Treatment outcome could be evaluated in 4 of them and all showed improvement after treatment. 14 patients(20%) had to change their regimens due to drug side effects. The most frequent side effect was elevation of liver enzymes(6 patients). Others included dizziness, hyperuricemia, tinnitus, skin rash, GI troubles. More than 50% of side effects developed within 3 months. In repeated drug sensitivity test, the concordance rate of resistance to INH was 100% and RFP 98%. EMB, PZA showed 80% concordance rate. But in the other drugs, the concordances were less than 50%. Operation was done in 5 patient - 1 patients as a adjunctive means of chemotherapy -. In that case, negative conversion of sputum AFB was done. Conclusion: 2/3 patients of multidrug-resistant tuberculosis were improved by appropriate prescription and regular medication suggesting that more aggressive management and monitoring is indicated in multidrug-resistant tuberculosis.

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A Study on Lubrication Characteristics of Automotive Engine Oil Merchandised in Domestic (국내 판매되는 자동차용 엔진오일의 윤활특성 연구)

  • Kim, Shin;Kang, Hyung-Kyu;Lim, Tae-Yoon;Kwon, Jong-Soo;Kim, Jai-Gueon;Choi, Dae-Sung;Kim, Dong-Kil;Jung, Choong-Sub
    • Tribology and Lubricants
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    • v.25 no.6
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    • pp.432-437
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    • 2009
  • The effect of oxidation in SAE 5W30 engine oils on friction and wear characteristics was investigated using reciprocating bench tester and shell 4-ball tester. Commercial engine oils were collected and oxidized using the KS M 2021 method modifying the oxidation time. Kinematic viscosity, total acid number(TAN), FT-IR spectrum and total base number(TBN) also measured to examine the chemical change of oils with oxidation. The results showed that TAN was slightly changed and Kinematic viscosity was suddenly increased during the oxidation stage. however, TBN results keep a constant slope after TBN linearly decreased with oxidation time. Spectroscopy results showed that spectrums were orderly increased at $1710cm^{-1}$ during the oxidation time. Friction test results showed that oxidation of oils formed unstable friction layers causing higher fluctuating friction. however, the wear resistance was independent of oxidized time due to the different friction characteristics by oxidation. We found several factors in relation to lubrication properties with oxidation time. This factors were Viscosity, TBN, change of FT-IR spectrum, friction coefficient using reciprocating bench tester and wear scar.

The Effect of Fitness Management Class on Body Composition, Blood Pressure and Health-related Fitness in College Women (체력관리 수업이 여자 대학생의 신체구성, 혈압 및 건강관련 체력에 미치는 영향)

  • Kim, Myoung-Su;Kim, Sung-Hee;Lee, Shin-Ho
    • Journal of Digital Convergence
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    • v.14 no.12
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    • pp.607-614
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    • 2016
  • This study investigated the effect of fitness management class on body composition, blood pressure and health-related fitness in college women. The subjects were to target college women of the 317 people to take nine semesters 2012-2016 school fitness management class, group division were divided underweight, thin-obesity, normal, normal-obesity and obesity by body mass index(BMI) and body fat(%). Fitness management classes consist of combined exercise(resistance and aerobic exercise) was conducted to exercise twice a week 75 minutes a day. Four groups except for the obese group, Fitness management class have a positive improvement effect on body weight, BMI, BF(%), muscle mass and waist circumference. In addition, five groups were positive improvement on blood pressure and health-related fitness variables. In conclusions, except for improving body composition in obese college women, fitness management classes had a positive improvement effect on body composition, blood pressure and health-related fitness in college women.

The Development of an Optimal Management System for Industrial Batteries (산업용 축전지 최적 관리시스템 개발)

  • Min, Byoung-Gwon;Ryu, Seung-Pyo;Shin, Hyun-Joo
    • Proceedings of the KIEE Conference
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    • 2002.07b
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    • pp.1009-1011
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    • 2002
  • Some defective cells in the battery bank of power systems using batteries result in deterioration of the performance of the total battery bank. Consequently, the battery bank can't perfectly back up the system in occurrence of any power problems and the overcharge of defective cells may lead to their explosion or the occurrence of fire. The developed battery management system in this study enables operators to telemeter and analyze internal resistance, voltages, currents, and temperatures of batteries at remote sites through a PC, so they can detect defective cells before the occurrence of power problems. And adoption of this system ensures extension of battery life.

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