• The Plant Pathology Journal
• /
• 제21권1호
• /
• pp.7-12
• /
• 2005

Plant growth-promoting rhizobacteria (PGPR) are a wide range of root-colonizing bacteria with the capacity to enhance plant growth and control plant pathogens. Here we review recent progress that indicate some PGPR strains release a blend of volatile organic compounds (VOCs) that promote growth in Arabidopsis seedlings and induce resistance against Erwinia carotovora subsp. carotovora. In particular, the volatile components 2,3-butanediol and acetoin released exclusively from the PGPR strains triggered the greatest level of growth promotion and induced systemic resistance. Pharmacological applications of 2,3-butanediol promoted the plant growth and induced resistance, while bacterial mutants blocked in 2,3-butanediol and acetoin synthesis was devoid of growth-promotion and induced resistance capacities. The results suggested that the bacterial VOCs play a critical role in the plant growth promotion and induced resistance by PGPR. Using transgenic and mutant lines of Arabidopsis, we provide evidences that the signal pathway activated by volatiles from one PGPR strain is dependent on cyto-kinin activation for growth promotion and dependent on an ethylene-signaling pathway for induced pathogen resistance. This discovery provides new insight into the role of bacterial VOCs as initiators of both plant growth promotion and defense responses in plants.

• 대한기계학회논문집A
• /
• 제23권7호
• /
• pp.1139-1146
• /
• 1999

Reliability analysis of structures based on fracture mechanics requires knowledge on statistical characteristics of the parameter C and m in the fatigue crack growth law, $da/dN=C({\Delta}K)^m$. The purpose of the present study is to investigate if it is possible to predict fatigue crack growth rate by only the fluctuation of the parameter C. In this study, Paris-Erdogan law is adopted, where the author treat the parameter C as random and m as constant. The fluctuation of crack growth rate is assumed only due to the parameter C. The growth resistance coefficient of material to fatigue crack growth (Z=1/C) was treated as a spatial stochastic process, which varies randomly on the crack path. The theoretical crack growth rates at various stress intensity factor range are discussed. Constant ${\Delta}K$ fatigue crack growth tests were performed on the structural steel, SM45C. The experimental data were analyzed to determine the autocorrelation function and Weibull distributions of the fatigue crack growth resistance. And also, the effect of the parameter m of Paris' law due to variation of fatigue crack growth resistance was discussed.

• Journal of Mechanical Science and Technology
• /
• 제14권10호
• /
• pp.1041-1050
• /
• 2000

In this paper the effect of specimen thickness on fatigue crack growth with the spatial distribution of material properties is presented. Basically, the material resistance to fatigue crack growth is treated as a spatial stochastic process, which varies randomly on the crack surface. The theoretical autocorrelation functions of fatigue crack growth resistance with specimen thickness are discussed for several correlation lengths. Constant ${\Delta}K$ fatigue crack growth tests were also performed on CT type specimens with three different thicknesses of BS 4360 steel. Applying the proposed stochastic model and statistical analysis procedure, the experimental data were analyzed for different specimen thicknesses for determining the autocorrelation functions and probability distributions of the fatigue crack growth resistance.

• 한국식물병리학회지
• /
• 제10권4호
• /
• pp.270-276
• /
• 1994

Mycelial growth resistant isolates of Botryosphaeria dothidea to benomyl showed 99~79% spore germination on the PSA media supplemented with 200~2,100 $\mu\textrm{g}$/ml of carbendazim and thiophanate-methyl to manifest the high cross-resistance in spore germination. Mycelial growth, 23~9 mm in colony diameter, also manifested the high cross-resistance of mycelial growth together with similarity of spore forming cross-resistance. Benomyl resistant isolates BR1, BR2 and BR3, grew 23~10 mm in colony diameter at 330~3,000 $\mu\textrm{g}$/ml of captafol, captan and oxine-copper showing the high double resistance of mycelial growth and spore formation with minor difference. However, within concentration range of the 3 fungicides tested, germinations of all the tested isolates were completely suppressed to show no double-resistance in the fungal spore germination.

• 한국해양공학회지
• /
• 제8권2호
• /
• pp.47-55
• /
• 1994

The purpose of the present study is to investigate the effect of specimen thickness on statistical properties of crack growth resistance. In this study, the resistance S$\delta$$_h$(x) to fatigue crack growth was treated as a spatial stochastic process. which varies randomly on the crack surface. The theoretical autocorrelation functions of the resistance to fatigue crack growth considering specimen thickness are discussed for several correlation lengths. The main results obtained are : (1) The theoretical autocorrelation functions of S$\delta$$_h$(x) are almost independent of specimen of specimen thickness except for the origin. (2) The variance increases with decreasing specimen thickness.

• 한국식품영양과학회지
• /
• 제23권2호
• /
• pp.293-297
• /
• 1994

The effect of organic acids on growth and heat resistance of Listeria monocytogenes Scott A were investigated. The growth of L. monocytogenes was inhibited in Tryptic Soy Broth(TSB) with 0.1 or 0.2% of acetic , tartic , propionic , citric and lactic acid at 35$^{\circ}C$, respectively. The growth of l. Monocytogenes did not occur in TSB with 0.2% of acetic acid or propionic acid during 48h of incubation. The heat resistance of L.monocytogenes was affected by kind of organic acid, ph and heating substrate. L.monocytogenes showed more heat resistant in TSB with various organic acids than in 0.1M sodium phosphate with the same organic acids. Heat resistance decreased as pH of heating substrate decreased . Surface-adherent microcolony was more heat resistant than planktonic cell of L. monocytogenes. Propionic and lactic acids more affected on heat resistance of L.monocytogenes than acetic , tartaric and citric acids.

• Tuberculosis and Respiratory Diseases
• /
• 제75권5호
• /
• pp.188-198
• /
• 2013

Over the past decade, several kinase inhibitors have been approved based on their clinical benefit in cancer patients. Unfortunately, in many cases, patients develop resistance to these agents via secondary mutations and alternative mechanisms. To date, several major mechanisms of acquired resistance, such as secondary mutation of the epidermal growth factor receptor (EGFR) gene, amplification of the MET gene and overexpression of hepatocyte growth factor, have been reported. This review describes the recent findings on the mechanisms of primary and acquired resistance to EGFR tyrosine kinase inhibitors and acquired resistance to anaplastic lymphoma kinase inhibitors, primarily focusing on non-small cell lung carcinoma.

• Journal of Mechanical Science and Technology
• /
• 제19권6호
• /
• pp.1338-1346
• /
• 2005

Effects of thermal contact resistance between heater and susceptor, susceptor and graphite board in a MOCVD reactor on temperature distribution and film growth rate were analyzed. One-dimensional thermal resistance model considering thermal contact resistance and heat transfer area was made up at first to find the temperature drop at the surface of graphite board. This one-dimensional model predicted the temperature drop of 18K at the board surface. Temperature distribution of a reactor wall from the three-dimensional computational fluid dynamics analysis including the gap at the wafer position showed the temperature drop of 20K. Film growth rates of InP and GaAs were predicted using computational fluid dynamics technique with chemical reaction model. Temperature distribution from the three-dimensional heat transfer calculation was used as a thermal boundary condition to the film growth rate simulations. Temperature drop due to the thermal contact resistance affected to the GaAs film growth a little but not to the InP film growth.

• 한국결정성장학회지
• /
• 제26권2호
• /
• pp.53-57
• /
• 2016

저항가열 방식으로 제작된 설비를 이용하여 SiC 단결정을 성장하였다. 성장 조건에 따라 결정의 성장 양상이 달랐으며, 원료부의 온도와 결정 성장부의 온도에 따라 각각 온도 설정이 필요함을 알았다. 본 논문에서는 SiC 결정의 성장 온도에 따른 성장 결과에 대하여 고찰해 보았으며, 이에 대한 결과를 보고하고자 한다.

• 한국환경과학회지
• /
• 제21권3호
• /
• pp.267-276
• /
• 2012

Spaceflights results in the reduction of immune status of human beings and increase in the virulence of microorganisms, especially gram negative bacteria. The growth of Klebsiella pneumoniae is enhanced by catecholamines and during spaceflight, elevation in the levels of cortisols occurs. So it is necessary to know the changes in physiology, virulence, antibiotic resistance and gene expression of K. pneumoniae under microgravity conditions. The present study was undertaken to study effect of simulated microgravity on growth, morphology, antibiotic resistance and cross stress resistance of K. pneumoniae to various stresses. The susceptibility of simulated microgravity grown K. pneumoniae to ampicillin, penicillin, streptomycin, kanamycin, hygromycin and rifampicin were evaluated. The growth of bacteria was found to be fast compared with normal gravity grown bacteria and no significant changes in the antibiotic resistance were found. The bacteria cultured under microgravity conferred cross stress resistance to acid, temperature and osmotic stress higher than the normal gravity cultured bacteria but the vice versa was found in case of oxidative stress.